Investigation of association between TLR9 gene polymorphisms and VKH in Japanese patients

Ocular Immunology and Inflammation

Volumn 19, Issue 3, 2011, Pages 202-205

  Ito, Ryuta ^a   Ota, Masao ^b   Meguro, Akira ^a   Katsuyama, Yoshihiko ^b   Uemoto, Riyo ^a   Nomura, Eiichi ^a   Nishide, Tadayuki ^a   Kitaichi, Nobuyoshi ^c   Horie, Yukihiro ^d   Namba, Kenichi ^d   Ohno, Shigeaki ^d   Inoko, Hidetoshi ^e   Mizuki, Nobuhisa ^a  

^a YOKOHAMA CITY UNIVERSITY   (Japan)

^b SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c HEALTH SCIENCES UNIVERSITY OF HOKKAIDO   (Japan)

^d HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^e TOKAI UNIVERSITY   (Japan)

Author keywords

genetics; intraocular inflammation; TLR9 polymorphism; VKH Syndrome

Indexed keywords

TOLL LIKE RECEPTOR 9;

ALLELE; ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; GENE LINKAGE DISEQUILIBRIUM; GENE LOCATION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HUMAN; JAPANESE; MAJOR CLINICAL STUDY; PHENOTYPE; SINGLE NUCLEOTIDE POLYMORPHISM; VOGT KOYANAGI SYNDROME;

ASIAN CONTINENTAL ANCESTRY GROUP; GENE FREQUENCY; GENOTYPE; HAPLOTYPES; HUMANS; LINKAGE DISEQUILIBRIUM; POLYMORPHISM, SINGLE NUCLEOTIDE; TOLL-LIKE RECEPTOR 9; UVEOMENINGOENCEPHALITIC SYNDROME;

EID: 79957484729     PISSN: 09273948     EISSN: 17445078     Source Type: Journal    
DOI: 10.3109/09273948.2011.553981     Document Type: Article

References (28)

1. Moorthy RS, Inomata H, Rao NA. Vogt-Koyanagi-Harada syndrome. Surv Ophthalmol. 1995;39(4): 265-292
2. Islam SM, Nugama J, Fujino Y, et al. Relation between the clinical course of Vogt-Koyanagi-Harada's disease and human leukocyte antigen (HLA)-DR4 subtypes. Nippon Ganka Gakkai Zasshi. 1994; 98: 797-801
3. Shindo Y, Inoko H, Yamamoto T, et al. HLA-DRB1 typing of VKH disease by PCR-RFLP and the strong association with DRB1*0405 and DRB1*0410 Br J Ophthalmol. 1994; 78: 223-226 (Pubitemid 24070634)
4. Damico FM, Cunha-Neto E, Goldberg AC, et al. T-cell recognition and cytokine profile induced by melanocyte epitopes in patients with HLA-DRB1*0405-positive and-negative Vogt-Koyanagi Harada uveitis. Invest Ophthalmol Vis Sci. 2005; 46;2465-2471 (Pubitemid 43119495)
5. Andreoli CM, Foster CS. Vogt-Koyanagi-Harada disease. Int Ophtalmol Clin. 2006; 46: 111-122 (Pubitemid 44084839)
6. Kim MH, Seong MC, Kwa NH, et al. Association of HLA with Vogt-Koyanagi-Harada syndrome in Koreans. Am J Ophtalmol. 2007; 15: 89-97
7. Norose K, Yano A. Melanoma specific Th1 cytotoxic T lymphocyte line in Vogt-Koyanagi-Harada disease. Br J Ophtalmol. 1996; 80: 10002-8
8. Sugita S, Takase H, Taguchi C, et al. Ocular infiltrating CD4+ T cells from patients with Vogt-Koyanagi-Harada disease recognize human melanocyte antigens. Invest Ophthalmol Vis Sci. 2006; 47: 2547-2554 (Pubitemid 351639840)
9. Chi W, Yang P, Li B, et al. IL-23 promotes CD4+ T cells to produce IL-17 in Vogt-Koyanagi-Harada disease. J Allergy Clin Immunol. 2007; 119: 1218-1224 (Pubitemid 46667160)
10. Chen L, Yang P, Zhou H, et al. Diminished frequency and function of CD4+D25 high regulatory T cells associated with active uveitis in Vogt-Koyanagi-Harada syndrome. Invest Ophthalmol Vis Sci. 2008; 49: 3475-3482
11. Maezawa N, Yano A, Taniguchi M, Kojima S. The role of cytotoxic T lymphocytes in the pathogenesis of Vogt-Koyanagi- Harada disease. Ophthalmologica. 1982;185(3): 179-186 (Pubitemid 12031627)
12. Minoda H, Sakai J, Sugiura M, Imai S, Osato T, Usui M. Nippon Ganka Gakkai Zasshi: high inducibility of Epstein-Barr virus replication in B lymphocytes in Vogt-Koyanagi-Harada disease. Nippon Ganka Gakkai Zasshi. 1999;103(4): 289-296 (Pubitemid 29220027)
13. Sugita S, Takase H, Kawaguchi T, Taguchi C, Mochizuki M. Cross-reaction between tyrosinase peptides and cytomegalovirus antigen by T cells from patients with Vogt-Koyanagi-Harada disease. Int Ophthalmol. 2007 Apr-Jun;27(2-3): 87-95 (Pubitemid 46909247)
14. Ito T, Wang YH, Liu YJ. Plasmacytoid dendritic cell precursors/ type I interferon-producing cells sense viral infection by Toll-like receptor (TLR 7) and TLR9 Springer Semin Immunopathol. 2005;26: 221-229
15. Sato A, Linehan MM, Iwasaki A. Dual recognition of herpes simplex viruses by TLR2 and TLR9 in dendritic cells. Proc Natl Acad Sci U S A. 2006; 103: 17343-17348 (Pubitemid 44788971)
16. Lazarus R, Klimecki WT, Raby BA, Vercelli D, et al. Singlenucleotide polymorphisms in the Toll-like receptor 9 gene (TLR): frequencies, pairwise linkage disequilibrium, and haplotypes in three US, ethnic groups and exploratory case-control disease association studies. Genomics. 2003; 81: 85-91 (Pubitemid 36263362)
17. Török HP, Glas J, Tonenchi L, Bruennler G, et al. Crohn's disease is associated with a toll-like receptor-9 polymorphism. Gastroenterology. 2004; 127: 365-366 (Pubitemid 38962306)
18. Hur JW, Shin HD, Park BL, Kim LH, et al. Association study of Toll-like receptor 9 gene polymorphism in Korean patients with systemic lupus erythematosus. Tissue Antigens. 2005; 65: 266-270 (Pubitemid 40342433)
19. Veltkamp M, van Moorsel CHM, Rijkers GT, et al. Toll-like receptor (TLR)-9 genetics and function in sarcoidosis. Clin Exp Immunol. 2010; 162: 68-74
20. Ito A, Ota M, Katsuyama Y, Inoko H, et al. Lack of association of Toll-like receptor 9 gene polymorphism with Behçet's disease in Japanese patients. Tissue Antigens. 2007; 70: 423-426 (Pubitemid 47537403)
21. Barrett JC, Fry B, Maller J, Daly MJ. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics. 2005; 21(2): 263-265 (Pubitemid 40202029)
22. Gabriel SB, Schaffner SF, Nguyen H, et al . The structure of haplotype blocks in the human genome. Science. 2002; 296(5576): 2225-2229 (Pubitemid 34680308)
23. Qin Z, Niu T, Liu J. Partition-ligation-expectationmaximization algorithm for haplotype inference with single-nucleotide polymorphisms. Am J Hum Genet. 2002; 71(5): 1242-1247 (Pubitemid 35305248)
24. Bauer S, Hacker KC, Redecke H, Hausmann S, et al. Human TLR9 confers responsiveness to bacterial DNA via speciesspecific CpG motif recognition. Proc Natl Acad Sci U S A. 2001; 98: 9237-9242 (Pubitemid 32743900)
25. Kindrachuk J, Potter JE, Brownlie R, et al. Nucleic acids exert a sequence-independent cooperative effect on sequence-dependent activation of toll-like receptor 9 J Biol Chem. 2007; 282: 13944-13953 (Pubitemid 47100464)
26. Minns LA, Menard LC, Foureau DM, et al. TLR9 is required for the gut-associated lymphoid tissue response following oral infection of toxoplasma gondii. J Immunol. 2006; 176: 7589-7597 (Pubitemid 43853053)
27. Takaoka A, Yanai H, Kondo S, et al. Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors. Nature. 2005;434: 243-249 (Pubitemid 40388058)
28. Bassili SS, Peyman GA, Gebhardt BM, et al. Detection of Epstein-Barr virus DNA by polymerase chain reaction in the vitreous from a patient with Vogt-Koyanagi-Harada syndrome. Retina. 1996; 16: 160-161 (Pubitemid 26120234)