메뉴 건너뛰기




Volumn 13, Issue 3, 2011, Pages 225-232

Pathogenesis of dermatomyositis: Role of cytokines and interferon

Author keywords

Cytokine; Dermatomyositis; Interface dermatitis; Interferon

Indexed keywords

AUTOANTIBODY; B CELL ACTIVATING FACTOR; CYTOKINE; GAMMA INTERFERON; INTERFERON; INTERFERON 3; INTERLEUKIN 10; INTERLEUKIN 15; INTERLEUKIN 17; INTERLEUKIN 18; INTERLEUKIN 6; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 79957455821     PISSN: 15233774     EISSN: 15346307     Source Type: Journal    
DOI: 10.1007/s11926-011-0166-x     Document Type: Article
Times cited : (53)

References (50)
  • 1
    • 0141651951 scopus 로고    scopus 로고
    • Polymyositis and dermatomyositis
    • DOI 10.1016/S0140-6736(03)14368-1
    • MC Dalakas R Hohlfeld 2003 Polymyositis and dermatomyositis Lancet 362 9388 971 82 14511932 10.1016/S0140-6736(03)14368-1 1:CAS:528: DC%2BD3sXnsVWqu7g%3D (Pubitemid 37159295)
    • (2003) Lancet , vol.362 , Issue.9388 , pp. 971-982
    • Dalakas, M.C.1    Hohlfeld, R.2
  • 2
    • 8344282691 scopus 로고    scopus 로고
    • Infiltrating cells, related cytokines and chemokine receptors in lesional skin of patients with dermatomyositis
    • DOI 10.1111/j.1365-2133.2004.06144.x
    • M Caproni, et al. 2004 Infiltrating cells, related cytokines and chemokine receptors in lesional skin of patients with dermatomyositis Br J Dermatol 151 4 784 91 15491417 10.1111/j.1365-2133.2004.06144.x 1:CAS:528:DC%2BD2cXhtVKitr3F (Pubitemid 39482111)
    • (2004) British Journal of Dermatology , vol.151 , Issue.4 , pp. 784-791
    • Caproni, M.1    Torchia, D.2    Cardinali, C.3    Volpi, W.4    Del Bianco, E.5    D'Agata, A.6    Fabbri, P.7
  • 3
    • 58349103703 scopus 로고    scopus 로고
    • Similar topology of injury to keratinocytes and myofibres in dermatomyositis skin and muscle
    • 19077075 10.1111/j.1365-2133.2008.08967.x 1:STN:280: DC%2BD1M7htlajsg%3D%3D
    • SA Greenberg D Fiorentino 2009 Similar topology of injury to keratinocytes and myofibres in dermatomyositis skin and muscle Br J Dermatol 160 2 464 5 19077075 10.1111/j.1365-2133.2008.08967.x 1:STN:280: DC%2BD1M7htlajsg%3D%3D
    • (2009) Br J Dermatol , vol.160 , Issue.2 , pp. 464-5
    • Greenberg, S.A.1    Fiorentino, D.2
  • 4
    • 33745080281 scopus 로고    scopus 로고
    • Cytokines in idiopathic inflammatory myopathies
    • DOI 10.1080/08916930600622256, PII K73821762043157
    • S Salomonsson IE Lundberg 2006 Cytokines in idiopathic inflammatory myopathies Autoimmunity 39 3 177 90 16769651 10.1080/08916930600622256 1:CAS:528:DC%2BD28XnsFGltb4%3D (Pubitemid 43879030)
    • (2006) Autoimmunity , vol.39 , Issue.3 , pp. 177-190
    • Salomonsson, S.1    Lundberg, I.E.2
  • 5
    • 70349789681 scopus 로고    scopus 로고
    • Role of cytokines and chemokines in idiopathic inflammatory myopathies
    • 19726994 10.1097/BOR.0b013e3283317b31
    • B De Paepe KK Creus JL De Bleecker 2009 Role of cytokines and chemokines in idiopathic inflammatory myopathies Curr Opin Rheumatol 21 6 610 6 19726994 10.1097/BOR.0b013e3283317b31
    • (2009) Curr Opin Rheumatol , vol.21 , Issue.6 , pp. 610-6
    • De Paepe, B.1    Creus, K.K.2    De Bleecker, J.L.3
  • 6
    • 57349185973 scopus 로고    scopus 로고
    • Cytokine gene polymorphisms as risk and severity factors for juvenile dermatomyositis
    • 19035492 10.1002/art.24039 1:CAS:528:DC%2BD1MXmt1ylug%3D%3D This was a large study of JDM patients showing that multiple TNF-α and IL-1 polymorphisms are risk and protective factors for JDM and that the TNF-α-308A allele has a much higher relative importance compared with all detected risk and other TNF-α and IL-1 cytokine polymorphisms
    • G Mamyrova, et al. 2008 Cytokine gene polymorphisms as risk and severity factors for juvenile dermatomyositis Arthritis Rheum 58 12 3941 50 19035492 10.1002/art.24039 1:CAS:528:DC%2BD1MXmt1ylug%3D%3D This was a large study of JDM patients showing that multiple TNF-α and IL-1 polymorphisms are risk and protective factors for JDM and that the TNF-α-308A allele has a much higher relative importance compared with all detected risk and other TNF-α and IL-1 cytokine polymorphisms
    • (2008) Arthritis Rheum , vol.58 , Issue.12 , pp. 3941-50
    • Mamyrova, G.1
  • 7
    • 77956392253 scopus 로고    scopus 로고
    • Gene-gene-sex interaction in cytokine gene polymorphisms revealed by serum interferon alpha phenotype in juvenile dermatomyositis
    • 20605164 10.1016/j.jpeds.2010.04.034 1:CAS:528:DC%2BC3cXhtFWqtb7F
    • TB Niewold, et al. 2010 Gene-gene-sex interaction in cytokine gene polymorphisms revealed by serum interferon alpha phenotype in juvenile dermatomyositis J Pediatr 157 4 653 7 20605164 10.1016/j.jpeds.2010.04.034 1:CAS:528:DC%2BC3cXhtFWqtb7F
    • (2010) J Pediatr , vol.157 , Issue.4 , pp. 653-7
    • Niewold, T.B.1
  • 8
    • 54549124536 scopus 로고    scopus 로고
    • A high incidence of disease flares in an open pilot study of infliximab in patients with refractory inflammatory myopathies
    • 18272672 10.1136/ard.2007.077974 1:CAS:528:DC%2BD1MXjs1OitA%3D%3D This study combined clinical, serologic, and histopathologic data from muscle to document that flares in DM (and other inflammatory myopathies) are seen following infliximab therapy, and provides some molecular evidence that these flares are associated with increased IFN activity in the blood and muscle
    • M Dastmalchi, et al. 2008 A high incidence of disease flares in an open pilot study of infliximab in patients with refractory inflammatory myopathies Ann Rheum Dis 67 12 1670 7 18272672 10.1136/ard.2007.077974 1:CAS:528: DC%2BD1MXjs1OitA%3D%3D This study combined clinical, serologic, and histopathologic data from muscle to document that flares in DM (and other inflammatory myopathies) are seen following infliximab therapy, and provides some molecular evidence that these flares are associated with increased IFN activity in the blood and muscle
    • (2008) Ann Rheum Dis , vol.67 , Issue.12 , pp. 1670-7
    • Dastmalchi, M.1
  • 9
    • 77950857508 scopus 로고    scopus 로고
    • Etanercept-induced anti-Jo-1-antibody-positive polymyositis in a patient with rheumatoid arthritis: A case report and review of the literature
    • 20143116 10.1007/s10067-009-1370-1
    • Y Ishikawa, et al. 2010 Etanercept-induced anti-Jo-1-antibody-positive polymyositis in a patient with rheumatoid arthritis: a case report and review of the literature Clin Rheumatol 29 5 563 6 20143116 10.1007/s10067-009-1370-1
    • (2010) Clin Rheumatol , vol.29 , Issue.5 , pp. 563-6
    • Ishikawa, Y.1
  • 10
    • 44349086922 scopus 로고    scopus 로고
    • IL-6 regulates MCP-1, ICAM-1 and IL-6 expression in human myoblasts
    • 18400310 10.1016/j.jneuroim.2008.02.005 1:CAS:528:DC%2BD1cXmsFKms7w%3D
    • M Marino, et al. 2008 IL-6 regulates MCP-1, ICAM-1 and IL-6 expression in human myoblasts J Neuroimmunol 196 1-2 41 8 18400310 10.1016/j.jneuroim.2008. 02.005 1:CAS:528:DC%2BD1cXmsFKms7w%3D
    • (2008) J Neuroimmunol , vol.196 , Issue.12 , pp. 41-8
    • Marino, M.1
  • 11
    • 77954222258 scopus 로고    scopus 로고
    • Expression of Toll-like receptor 3 and Toll-like receptor 7 in muscle is characteristic of inflammatory myopathy and is differentially regulated by Th1 and Th17 cytokines
    • 20309865 1:CAS:528:DC%2BC3cXht1aqsL3I This was the first demonstration of TLR3 and TLR7 expression by inflammatory cells and myoblasts in DM, demonstrating preferential expression in regenerating myoblasts that is stimulated by dying myoblasts or nucleic acids, which might provide a mechanism for feed-forward acceleration of IFN production and inflammation
    • A Tournadre V Lenief P Miossec 2010 Expression of Toll-like receptor 3 and Toll-like receptor 7 in muscle is characteristic of inflammatory myopathy and is differentially regulated by Th1 and Th17 cytokines Arthritis Rheum 62 7 2144 51 20309865 1:CAS:528:DC%2BC3cXht1aqsL3I This was the first demonstration of TLR3 and TLR7 expression by inflammatory cells and myoblasts in DM, demonstrating preferential expression in regenerating myoblasts that is stimulated by dying myoblasts or nucleic acids, which might provide a mechanism for feed-forward acceleration of IFN production and inflammation
    • (2010) Arthritis Rheum , vol.62 , Issue.7 , pp. 2144-51
    • Tournadre, A.1    Lenief, V.2    Miossec, P.3
  • 12
    • 70350523961 scopus 로고    scopus 로고
    • Interleukin-6 and type i interferon-regulated genes and chemokines mark disease activity in dermatomyositis
    • 19877033 10.1002/art.24936 1:CAS:528:DC%2BD1MXhsFentLzK Investigators showed a positive correlation between blood levels of three IFN-induced chemokines, IL-6, and disease activity in DM. It is the largest study to date to correlate validated clinical activity measures with levels of circulating candidate biomarker proteins in adult patients with DM
    • H Bilgic, et al. 2009 Interleukin-6 and type I interferon-regulated genes and chemokines mark disease activity in dermatomyositis Arthritis Rheum 60 11 3436 46 19877033 10.1002/art.24936 1:CAS:528:DC%2BD1MXhsFentLzK Investigators showed a positive correlation between blood levels of three IFN-induced chemokines, IL-6, and disease activity in DM. It is the largest study to date to correlate validated clinical activity measures with levels of circulating candidate biomarker proteins in adult patients with DM
    • (2009) Arthritis Rheum , vol.60 , Issue.11 , pp. 3436-46
    • Bilgic, H.1
  • 13
    • 0035993995 scopus 로고    scopus 로고
    • Increased IL-15 production of muscle cells in polymyositis and dermatomyositis
    • 12147628 10.1093/intimm/dxf062 1:CAS:528:DC%2BD38XmsVKjtbk%3D
    • T Sugiura, et al. 2002 Increased IL-15 production of muscle cells in polymyositis and dermatomyositis Int Immunol 14 8 917 24 12147628 10.1093/intimm/dxf062 1:CAS:528:DC%2BD38XmsVKjtbk%3D
    • (2002) Int Immunol , vol.14 , Issue.8 , pp. 917-24
    • Sugiura, T.1
  • 15
    • 84863515135 scopus 로고    scopus 로고
    • Serum concentration of interleukin 15, interleukin 2 receptor and TNF receptor in patients with polymyositis and dermatomyositis: Correlation to disease activity
    • Mielnik P, et al. Serum concentration of interleukin 15, interleukin 2 receptor and TNF receptor in patients with polymyositis and dermatomyositis: correlation to disease activity. Rheumatol Int. 2010.
    • (2010) Rheumatol Int.
    • Mielnik, P.1
  • 16
    • 0347719268 scopus 로고    scopus 로고
    • Anatomic localization of immature and mature dendritic cell subsets in dermatomyositis and polymyositis: Interaction with chemokines and Th1 cytokine-producing cells
    • DOI 10.1002/art.11428
    • G Page G Chevrel P Miossec 2004 Anatomic localization of immature and mature dendritic cell subsets in dermatomyositis and polymyositis: Interaction with chemokines and Th1 cytokine-producing cells Arthritis Rheum 50 1 199 208 14730617 10.1002/art.11428 1:CAS:528:DC%2BD2cXht1Kru7k%3D (Pubitemid 38084305)
    • (2004) Arthritis and Rheumatism , vol.50 , Issue.1 , pp. 199-208
    • Page, G.1    Chevrel, G.2    Miossec, P.3
  • 17
    • 77956857329 scopus 로고    scopus 로고
    • Idiopathic inflammatory myopathies, signified by distinctive peripheral cytokines, chemokines and the TNF family members B-cell activating factor and a proliferation inducing ligand
    • 10.1093/rheumatology/keq151 1:CAS:528:DC%2BC3cXhtFGhtLfE
    • P Szodoray, et al. 2010 Idiopathic inflammatory myopathies, signified by distinctive peripheral cytokines, chemokines and the TNF family members B-cell activating factor and a proliferation inducing ligand Rheumatology (Oxford) 49 10 1867 77 10.1093/rheumatology/keq151 1:CAS:528:DC%2BC3cXhtFGhtLfE
    • (2010) Rheumatology (Oxford) , vol.49 , Issue.10 , pp. 1867-77
    • Szodoray, P.1
  • 18
    • 34648840848 scopus 로고    scopus 로고
    • Increased IL-18 production by dendritic cells in active inflammatory myopathies
    • DOI 10.1196/annals.1381.020, Autoimmunity, Part C The Mosaic of Autoimmunity
    • M Tucci, et al. 2007 Increased IL-18 production by dendritic cells in active inflammatory myopathies Ann NY Acad Sci 1107 184 92 17804546 10.1196/annals.1381.020 1:CAS:528:DC%2BD2sXhtVShs7jK (Pubitemid 47528795)
    • (2007) Annals of the New York Academy of Sciences , vol.1107 , pp. 184-192
    • Tucci, M.1    Quatraro, C.2    Dammacco, F.3    Silvestris, F.4
  • 19
    • 77956861432 scopus 로고    scopus 로고
    • Interleukin-18 is a key mediator in dermatomyositis: Potential contribution to development of interstitial lung disease
    • 10.1093/rheumatology/keq196 1:CAS:528:DC%2BC3cXhtFGhtb7O
    • T Gono, et al. 2010 Interleukin-18 is a key mediator in dermatomyositis: potential contribution to development of interstitial lung disease Rheumatology (Oxford) 49 10 1878 81 10.1093/rheumatology/keq196 1:CAS:528:DC%2BC3cXhtFGhtb7O
    • (2010) Rheumatology (Oxford) , vol.49 , Issue.10 , pp. 1878-81
    • Gono, T.1
  • 20
    • 67449132637 scopus 로고    scopus 로고
    • Increased serum levels of B cell activating factor (BAFF) in subsets of patients with idiopathic inflammatory myopathies
    • 18628284 10.1136/ard.2008.091405 1:CAS:528:DC%2BD1MXotVCjtLY%3D
    • O Krystufkova, et al. 2009 Increased serum levels of B cell activating factor (BAFF) in subsets of patients with idiopathic inflammatory myopathies Ann Rheum Dis 68 6 836 43 18628284 10.1136/ard.2008.091405 1:CAS:528: DC%2BD1MXotVCjtLY%3D
    • (2009) Ann Rheum Dis , vol.68 , Issue.6 , pp. 836-43
    • Krystufkova, O.1
  • 21
    • 77958151436 scopus 로고    scopus 로고
    • Characterization of regulatory T cells in patients with dermatomyositis
    • 20843660 10.1016/j.jaut.2010.07.006 1:CAS:528:DC%2BC3cXhtlCgtrjN
    • E Antiga, et al. 2010 Characterization of regulatory T cells in patients with dermatomyositis J Autoimmun 35 4 342 50 20843660 10.1016/j.jaut.2010.07.006 1:CAS:528:DC%2BC3cXhtlCgtrjN
    • (2010) J Autoimmun , vol.35 , Issue.4 , pp. 342-50
    • Antiga, E.1
  • 22
    • 0029812789 scopus 로고    scopus 로고
    • Abnormal numbers of cytokine producing cells in patients with polymyositis and dermatomyositis
    • E Hagiwara, et al. 1996 Abnormal numbers of cytokine producing cells in patients with polymyositis and dermatomyositis Clin Exp Rheumatol 14 5 485 91 8913649 1:STN:280:DyaK2s%2FntVOhsQ%3D%3D (Pubitemid 26335471)
    • (1996) Clinical and Experimental Rheumatology , vol.14 , Issue.5 , pp. 485-491
    • Hagiwara, E.1    Adams, E.M.2    Plotz, P.H.3    Klinman, D.M.4
  • 23
    • 33748030441 scopus 로고    scopus 로고
    • Genetically determined imbalance between serum levels of tumour necrosis factor (TNF) and interleukin (IL)-10 is associated with anti-Jo-1 and anti-Ro52 autoantibodies in patients with poly- and dermatomyositis
    • DOI 10.1016/j.jaut.2006.06.003, PII S0896841106000473
    • AB Hassan, et al. 2006 Genetically determined imbalance between serum levels of tumour necrosis factor (TNF) and interleukin (IL)-10 is associated with anti-Jo-1 and anti-Ro52 autoantibodies in patients with poly- and dermatomyositis J Autoimmun 27 1 62 8 16895750 10.1016/j.jaut.2006.06.003 1:CAS:528:DC%2BD28Xosl2qsL8%3D (Pubitemid 44294854)
    • (2006) Journal of Autoimmunity , vol.27 , Issue.1 , pp. 62-68
    • Hassan, A.B.1    Fathi, M.2    Dastmalchi, M.3    Lundberg, I.E.4    Padyukov, L.5
  • 24
    • 75149189005 scopus 로고    scopus 로고
    • Type i interferons: Crucial participants in disease amplification in autoimmunity
    • 20046205 10.1038/nrrheum.2009.237 1:CAS:528:DC%2BC3cXotlSh This is an outstanding review of IFN and its relationship to autoimmunity
    • JC Hall A Rosen 2010 Type I interferons: crucial participants in disease amplification in autoimmunity Nat Rev Rheumatol 6 1 40 9 20046205 10.1038/nrrheum.2009.237 1:CAS:528:DC%2BC3cXotlSh This is an outstanding review of IFN and its relationship to autoimmunity
    • (2010) Nat Rev Rheumatol , vol.6 , Issue.1 , pp. 40-9
    • Hall, J.C.1    Rosen, A.2
  • 25
    • 77953479308 scopus 로고    scopus 로고
    • Type 1 interferons and myositis
    • 20392291
    • SA Greenberg 2010 Type 1 interferons and myositis Arthritis Res Ther 12 Suppl 1 S4 20392291
    • (2010) Arthritis Res Ther , vol.12 , Issue.SUPPL. 1 , pp. 4
    • Greenberg, S.A.1
  • 27
    • 77950826805 scopus 로고    scopus 로고
    • The phenotypic profile of dermatomyositis and lupus erythematosus: A comparative analysis
    • Magro CM, et al. The phenotypic profile of dermatomyositis and lupus erythematosus: a comparative analysis. J Cutan Pathol. 2010;37(6):659-71.
    • (2010) J Cutan Pathol. , vol.37 , Issue.6 , pp. 659-671
    • Magro, C.M.1
  • 28
    • 34848898509 scopus 로고    scopus 로고
    • A possible mechanism for endogenous activation of the type I interferon system in myositis patients with anti-Jo-1 or anti-Ro 52/anti-Ro 60 autoantibodies
    • DOI 10.1002/art.22860
    • ML Eloranta, et al. 2007 A possible mechanism for endogenous activation of the type I interferon system in myositis patients with anti-Jo-1 or anti-Ro 52/anti-Ro 60 autoantibodies Arthritis Rheum 56 9 3112 24 17763410 10.1002/art.22860 1:CAS:528:DC%2BD2sXht1GgtbrO (Pubitemid 47502759)
    • (2007) Arthritis and Rheumatism , vol.56 , Issue.9 , pp. 3112-3124
    • Eloranta, M.-L.1    Helmers, S.B.2    Ulfgren, A.-K.3    Ronnblom, L.4    Alm, G.V.5    Lundberg, I.E.6
  • 29
    • 54349093937 scopus 로고    scopus 로고
    • Fiorentino D, Genomic analyses identify abnormalities in lipid metabolism in dermatomyositis patients
    • B Kea R Pesich L Chung P Brown D Fiorentino 2007 Fiorentino D, Genomic analyses identify abnormalities in lipid metabolism in dermatomyositis patients J Invest Dermatol 127 S1 12
    • (2007) J Invest Dermatol , vol.127 , Issue.S1 , pp. 12
    • Kea, B.1    Pesich, R.2    Chung, L.3    Brown, P.4    Fiorentino, D.5
  • 30
    • 51749123985 scopus 로고    scopus 로고
    • An IFN-associated cytotoxic cellular immune response against viral, self-, or tumor antigens is a common pathogenetic feature in "interface dermatitis."
    • 18418411 10.1038/jid.2008.96 1:CAS:528:DC%2BD1cXhtFSltbzO This is an excellent review of the relationship between IFN signature and interface dermatitis in the skin
    • J Wenzel T Tuting 2008 An IFN-associated cytotoxic cellular immune response against viral, self-, or tumor antigens is a common pathogenetic feature in "interface dermatitis." J Invest Dermatol 128 10 2392 402 18418411 10.1038/jid.2008.96 1:CAS:528:DC%2BD1cXhtFSltbzO This is an excellent review of the relationship between IFN signature and interface dermatitis in the skin
    • (2008) J Invest Dermatol , vol.128 , Issue.10 , pp. 2392-402
    • Wenzel, J.1    Tuting, T.2
  • 33
    • 77649298737 scopus 로고    scopus 로고
    • Interferon-stimulated gene 15 (ISG15) conjugates proteins in dermatomyositis muscle with perifascicular atrophy
    • 20186858 10.1002/ana.21805 1:CAS:528:DC%2BC3cXksVGgu7s%3D This was the first report to indicate that the ubiquitin conjugating system is activated in the muscle of DM patients and that abnormal protein conjugates with ISG-15 protein are present in tissue and inducible by type 1 IFN. It correlates expression of these proteins involved in conjugation with perifascicular atrophy of muscle fibers
    • M Salajegheh, et al. 2010 Interferon-stimulated gene 15 (ISG15) conjugates proteins in dermatomyositis muscle with perifascicular atrophy Ann Neurol 67 1 53 63 20186858 10.1002/ana.21805 1:CAS:528:DC%2BC3cXksVGgu7s%3D This was the first report to indicate that the ubiquitin conjugating system is activated in the muscle of DM patients and that abnormal protein conjugates with ISG-15 protein are present in tissue and inducible by type 1 IFN. It correlates expression of these proteins involved in conjugation with perifascicular atrophy of muscle fibers
    • (2010) Ann Neurol , vol.67 , Issue.1 , pp. 53-63
    • Salajegheh, M.1
  • 34
    • 26844496787 scopus 로고    scopus 로고
    • Association between lack of angiogenic response in muscle tissue and high expression of angiostatic ELR-negative CXC chemokines in patients with juvenile dermatomyositis: Possible link to vasculopathy
    • DOI 10.1002/art.21303
    • N Fall, et al. 2005 Association between lack of angiogenic response in muscle tissue and high expression of angiostatic ELR-negative CXC chemokines in patients with juvenile dermatomyositis: possible link to vasculopathy Arthritis Rheum 52 10 3175 80 16200621 10.1002/art.21303 1:CAS:528:DC%2BD2MXhtF2msrvO (Pubitemid 41447100)
    • (2005) Arthritis and Rheumatism , vol.52 , Issue.10 , pp. 3175-3180
    • Fall, N.1    Bove, K.E.2    Stringer, K.3    Lovell, D.J.4    Brunner, H.I.5    Weiss, J.6    Higgins, G.C.7    Bowyer, S.L.8    Graham, T.B.9    Thornton, S.10    Grom, A.A.11
  • 35
    • 33744475615 scopus 로고    scopus 로고
    • Type I interferon-associated skin recruitment of CXCR3+ lymphocytes in dermatomyositis
    • DOI 10.1111/j.1365-2230.2006.02150.x
    • J Wenzel, et al. 2006 Type I interferon-associated skin recruitment of CXCR3+ lymphocytes in dermatomyositis Clin Exp Dermatol 31 4 576 82 16716166 10.1111/j.1365-2230.2006.02150.x 1:STN:280:DC%2BD283oslSluw%3D%3D (Pubitemid 43806596)
    • (2006) Clinical and Experimental Dermatology , vol.31 , Issue.4 , pp. 576-582
    • Wenzel, J.1    Schmidt, R.2    Proelss, J.3    Zahn, S.4    Bieber, T.5    Tuting, T.6
  • 36
    • 33746797290 scopus 로고    scopus 로고
    • MxA gene expression in juvenile dermatomyositis peripheral blood mononuclear cells: Association with muscle involvement
    • DOI 10.1016/j.clim.2006.05.011, PII S1521661606007492
    • KA O'Connor, et al. 2006 MxA gene expression in juvenile dermatomyositis peripheral blood mononuclear cells: association with muscle involvement Clin Immunol 120 3 319 25 16859997 10.1016/j.clim.2006.05.011 (Pubitemid 44175902)
    • (2006) Clinical Immunology , vol.120 , Issue.3 , pp. 319-325
    • O'Connor, K.A.1    Abbott, K.A.2    Sabin, B.3    Kuroda, M.4    Pachman, L.M.5
  • 37
    • 2642528779 scopus 로고    scopus 로고
    • Induction of interferon-α production in plasmacytoid dendritic cells by immune complexes containing nucleic acid released by necrotic or late apoptotic cells and lupus IgG
    • DOI 10.1002/art.20254
    • T Lovgren, et al. 2004 Induction of interferon-alpha production in plasmacytoid dendritic cells by immune complexes containing nucleic acid released by necrotic or late apoptotic cells and lupus IgG Arthritis Rheum 50 6 1861 72 15188363 10.1002/art.20254 (Pubitemid 38725099)
    • (2004) Arthritis and Rheumatism , vol.50 , Issue.6 , pp. 1861-1872
    • Lovgren, T.1    Eloranta, M.-L.2    Bave, U.3    Alm, G.V.4    Ronnblom, L.5
  • 38
    • 79957484832 scopus 로고    scopus 로고
    • Serum levels of interferon {alpha} do not correlate with disease activity in patients with dermatomyositis/polymyositis
    • Krol P, et al. Serum levels of interferon {alpha} do not correlate with disease activity in patients with dermatomyositis/polymyositis. Ann Rheum Dis. 2010. This study failed to find a positive correlation with circulating IFN-α levels and muscle disease activity in patients with DM as measured by MRI of muscles. It suggests that the relationship between IFN-α levels, the IFN signature in blood, and disease activity in DM is complex.
    • (2010) Ann Rheum Dis.
    • Krol, P.1
  • 40
    • 33745034931 scopus 로고    scopus 로고
    • Functional assay of type I interferon in systemic lupus erythematosus plasma and association with anti-RNA binding protein autoantibodies
    • DOI 10.1002/art.21890
    • J Hua, et al. 2006 Functional assay of type I interferon in systemic lupus erythematosus plasma and association with anti-RNA binding protein autoantibodies Arthritis Rheum 54 6 1906 16 16736505 10.1002/art.21890 1:CAS:528:DC%2BD28Xms1Sisr8%3D (Pubitemid 43877940)
    • (2006) Arthritis and Rheumatism , vol.54 , Issue.6 , pp. 1906-1916
    • Hua, J.1    Kirou, K.2    Lee, C.3    Crow, M.K.4
  • 41
    • 66449121844 scopus 로고    scopus 로고
    • Elevated serum interferon-alpha activity in juvenile dermatomyositis: Associations with disease activity at diagnosis and after thirty-six months of therapy
    • 19479879 10.1002/art.24555 1:CAS:528:DC%2BD1MXotVeqt70%3D
    • TB Niewold, et al. 2009 Elevated serum interferon-alpha activity in juvenile dermatomyositis: associations with disease activity at diagnosis and after thirty-six months of therapy Arthritis Rheum 60 6 1815 24 19479879 10.1002/art.24555 1:CAS:528:DC%2BD1MXotVeqt70%3D
    • (2009) Arthritis Rheum , vol.60 , Issue.6 , pp. 1815-24
    • Niewold, T.B.1
  • 42
    • 0034659757 scopus 로고    scopus 로고
    • Increased CD40 expression on muscle cells of polymyositis and dermatomyositis: Role of CD40-CD40 ligand interaction in IL-6, IL-8, IL-15, and monocyte chemoattractant protein-1 production
    • T Sugiura, et al. 2000 Increased CD40 expression on muscle cells of polymyositis and dermatomyositis: role of CD40-CD40 ligand interaction in IL-6, IL-8, IL-15, and monocyte chemoattractant protein-1 production J Immunol 164 12 6593 600 10843719 1:CAS:528:DC%2BD3cXktFWlurs%3D (Pubitemid 30408846)
    • (2000) Journal of Immunology , vol.164 , Issue.12 , pp. 6593-6600
    • Sugiura, T.1    Kawaguchi, Y.2    Harigai, M.3    Takagi, K.4    Ohta, S.5    Fukasawa, C.6    Hara, M.7    Kamatani, N.8
  • 43
    • 0030904859 scopus 로고    scopus 로고
    • Cytokine production in muscle tissue of patients with idiopathic inflammatory myopathies
    • I Lundberg, et al. 1997 Cytokine production in muscle tissue of patients with idiopathic inflammatory myopathies Arthritis Rheum 40 5 865 74 9153548 10.1002/art.1780400514 1:CAS:528:DyaK2sXjsV2hsLw%3D (Pubitemid 27200003)
    • (1997) Arthritis and Rheumatism , vol.40 , Issue.5 , pp. 865-874
    • Lundberg, I.1    Ulfgren, A.-K.2    Nyberg, P.3    Andersson, U.4    Klareskog, L.5
  • 45
    • 77349088003 scopus 로고    scopus 로고
    • Unraveling the functions of plasmacytoid dendritic cells during viral infections, autoimmunity, and tolerance
    • 20193017 10.1111/j.0105-2896.2009.00881.x 1:CAS:528:DC%2BC3cXjslart74%3D
    • M Swiecki M Colonna 2010 Unraveling the functions of plasmacytoid dendritic cells during viral infections, autoimmunity, and tolerance Immunol Rev 234 1 142 62 20193017 10.1111/j.0105-2896.2009.00881.x 1:CAS:528: DC%2BC3cXjslart74%3D
    • (2010) Immunol Rev , vol.234 , Issue.1 , pp. 142-62
    • Swiecki, M.1    Colonna, M.2
  • 46
    • 42049093255 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells are present in cutaneous dermatomyositis lesions in a pattern distinct from lupus erythematosus
    • DOI 10.1111/j.1600-0560.2007.00848.x
    • JM McNiff DH Kaplan 2008 Plasmacytoid dendritic cells are present in cutaneous dermatomyositis lesions in a pattern distinct from lupus erythematosus J Cutan Pathol 35 5 452 6 18005168 10.1111/j.1600-0560.2007.00848.x This is a comparison of the histologic location of pDCs in the skin of DM patients versus lupus patients. This paper provides evidence suggesting that pDCs might have different functions in different autoimmune skin diseases due to their different locations (Pubitemid 351519413)
    • (2008) Journal of Cutaneous Pathology , vol.35 , Issue.5 , pp. 452-456
    • McNiff, J.M.1    Kaplan, D.H.2
  • 48
    • 77956371046 scopus 로고    scopus 로고
    • Lesional and nonlesional skin from patients with untreated juvenile dermatomyositis displays increased numbers of mast cells and mature plasmacytoid dendritic cells
    • 20506305 10.1002/art.27529
    • S Shrestha, et al. 2010 Lesional and nonlesional skin from patients with untreated juvenile dermatomyositis displays increased numbers of mast cells and mature plasmacytoid dendritic cells Arthritis Rheum 62 9 2813 22 20506305 10.1002/art.27529
    • (2010) Arthritis Rheum , vol.62 , Issue.9 , pp. 2813-22
    • Shrestha, S.1
  • 49
    • 78650261558 scopus 로고    scopus 로고
    • Evidence for a pathophysiological role of keratinocyte-derived type III interferon (IFNlambda) in cutaneous lupus erythematosus
    • Zahn S, et al. Evidence for a pathophysiological role of keratinocyte-derived type III interferon (IFNlambda) in cutaneous lupus erythematosus. J Invest Dermatol. 2011;131(1):133-40.
    • (2011) J Invest Dermatol. , vol.131 , Issue.1 , pp. 133-140
    • Zahn, S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.