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Volumn 6, Issue 3, 2011, Pages 203-212

TP receptor activation and inhibition in atherothrombosis: The paradigm of diabetes mellitus

Author keywords

Aspirin; Atherothrombosis; Diabetes mellitus; Oxidative stress; TP antagonism

Indexed keywords

ACETYLSALICYLIC ACID; ANTITHROMBOCYTIC AGENT; THROMBOXANE RECEPTOR;

EID: 79956302853     PISSN: 18280447     EISSN: 19709366     Source Type: Journal    
DOI: 10.1007/s11739-010-0440-3     Document Type: Review
Times cited : (26)

References (50)
  • 1
    • 42149084993 scopus 로고    scopus 로고
    • Diabetes patients requiring glucose-lowering therapy and nondiabetics with a prior myocardial infarction carry the same cardiovascular risk: a population study of 3.3 million people
    • Schramm TK, Gislason GH, Kober L et al (2008) Diabetes patients requiring glucose-lowering therapy and nondiabetics with a prior myocardial infarction carry the same cardiovascular risk: a population study of 3. 3 million people. Circulation 117: 1945-1954.
    • (2008) Circulation , vol.117 , pp. 1945-1954
    • Schramm, T.K.1    Gislason, G.H.2    Kober, L.3
  • 4
    • 33645678090 scopus 로고    scopus 로고
    • Blood platelet abnormalities and pharmacological modulation of platelet reactivity in patients with diabetes mellitus
    • Watala C, Boncler M, Gresner P (2005) Blood platelet abnormalities and pharmacological modulation of platelet reactivity in patients with diabetes mellitus. Pharmacol Rep 57(Suppl): S42-58.
    • (2005) Pharmacol Rep , vol.57 , Issue.SUPPL. , pp. 42-58
    • Watala, C.1    Boncler, M.2    Gresner, P.3
  • 5
    • 0037046196 scopus 로고    scopus 로고
    • Aspirin-resistant thromboxane biosynthesis and the risk of myocardial infarction, stroke, or cardiovascular death in patients at high risk for cardiovascular events
    • Eikelboom JW, Hirsh J, Weitz JI, Johnston M, Yi Q, Yusuf S (2002) Aspirin-resistant thromboxane biosynthesis and the risk of myocardial infarction, stroke, or cardiovascular death in patients at high risk for cardiovascular events. Circulation 105: 1650-1655.
    • (2002) Circulation , vol.105 , pp. 1650-1655
    • Eikelboom, J.W.1    Hirsh, J.2    Weitz, J.I.3    Johnston, M.4    Yi, Q.5    Yusuf, S.6
  • 8
    • 37249068049 scopus 로고    scopus 로고
    • Platelet activation and atherothrombosis
    • Davì G, Patrono C (2007) Platelet activation and atherothrombosis. N Engl J Med 357: 2482-2494.
    • (2007) N Engl J Med , vol.357 , pp. 2482-2494
    • Davì, G.1    Patrono, C.2
  • 10
    • 42649113385 scopus 로고    scopus 로고
    • 2: physiology/pathophysiology, cellular signal transduction and pharmacology
    • 2: physiology/pathophysiology, cellular signal transduction and pharmacology. Pharmacol Ther 118: 18-35.
    • (2008) Pharmacol Ther , vol.118 , pp. 18-35
    • Nakahata, N.1
  • 11
    • 9644272529 scopus 로고    scopus 로고
    • 2 and prostacyclin in the development of atherosclerosis in apoE-deficient mice
    • 2 and prostacyclin in the development of atherosclerosis in apoE-deficient mice. J Clin Invest 114: 784-794.
    • (2004) J Clin Invest , vol.114 , pp. 784-794
    • Kobayashi, T.1    Tahara, Y.2    Matsumoto, M.3
  • 12
    • 63849160095 scopus 로고    scopus 로고
    • 2 modulates migration, proliferation, and differentiation of adipose tissue-derived mesenchymal stem cells
    • 2 modulates migration, proliferation, and differentiation of adipose tissue-derived mesenchymal stem cells. Exp Mol Med 41: 17-24.
    • (2009) Exp Mol Med , vol.41 , pp. 17-24
    • Yun, D.H.1    Song, H.Y.2    Lee, M.J.3
  • 14
    • 0030825166 scopus 로고    scopus 로고
    • 2, and specific receptor antagonists on vascular smooth muscle cell proliferation
    • 2, and specific receptor antagonists on vascular smooth muscle cell proliferation. Circulation 96: 2280-2286.
    • (1997) Circulation , vol.96 , pp. 2280-2286
    • Pakala, R.1    Willerson, J.T.2    Benedict, C.R.3
  • 15
    • 0022602060 scopus 로고
    • Leukotrienes potentiate the effects of epinephrine and thrombin on human platelet aggregation
    • Mehta P, Mehta J, Lawson D, Krop I, Letts LG (1986) Leukotrienes potentiate the effects of epinephrine and thrombin on human platelet aggregation. Thromb Res 41: 731-738.
    • (1986) Thromb Res , vol.41 , pp. 731-738
    • Mehta, P.1    Mehta, J.2    Lawson, D.3    Krop, I.4    Letts, L.G.5
  • 18
    • 0033613968 scopus 로고    scopus 로고
    • Phosphorylation of the thromboxane receptor α, the predominant isoform expressed in human platelets
    • Habib A, FitzGerald GA, Maclouf J (1999) Phosphorylation of the thromboxane receptor α, the predominant isoform expressed in human platelets. J Biol Chem 274: 2645-2651.
    • (1999) J Biol Chem , vol.274 , pp. 2645-2651
    • Habib, A.1    Fitzgerald, G.A.2    Maclouf, J.3
  • 19
    • 0029664751 scopus 로고    scopus 로고
    • 2 receptor isoforms in human platelets. Opposite coupling to adenylcyclase with different sensitivity to Arg60 to Leu mutation
    • 2 receptor isoforms in human platelets. Opposite coupling to adenylcyclase with different sensitivity to Arg60 to Leu mutation. J Clin Invest 97: 949-956.
    • (1996) J Clin Invest , vol.97 , pp. 949-956
    • Hirata, T.1    Ushikubi, F.2    Kakizuka, A.3    Okuma, M.4    Narumiya, S.5
  • 20
    • 27744487524 scopus 로고    scopus 로고
    • 2 receptor antagonist S18886 prevents enhanced atherogenesis caused by diabetes mellitus
    • 2 receptor antagonist S18886 prevents enhanced atherogenesis caused by diabetes mellitus. Circulation 112: 3001-3008.
    • (2005) Circulation , vol.112 , pp. 3001-3008
    • Zuccollo, A.1    Shi, C.2    Mastroianni, R.3
  • 21
    • 25144437017 scopus 로고    scopus 로고
    • The specific thromboxane receptor antagonist S18886: pharmacokinetic and pharmacodynamic studies
    • Gaussem P, Reny JL, Thalamas C et al (2005) The specific thromboxane receptor antagonist S18886: pharmacokinetic and pharmacodynamic studies. J Thromb Haemost 3: 1437-1445.
    • (2005) J Thromb Haemost , vol.3 , pp. 1437-1445
    • Gaussem, P.1    Reny, J.L.2    Thalamas, C.3
  • 22
    • 65949110335 scopus 로고    scopus 로고
    • TP receptor antagonism: a new concept in atherothrombosis and stroke prevention
    • Chamorro A (2009) TP receptor antagonism: a new concept in atherothrombosis and stroke prevention. Cerebrovasc Dis 27(Suppl): 20-27.
    • (2009) Cerebrovasc Dis , vol.27 , Issue.SUPPL. , pp. 20-27
    • Chamorro, A.1
  • 23
    • 12844278633 scopus 로고    scopus 로고
    • Cyclooxygenases, thromboxane, and atherosclerosis: plaque destabilization by cyclooxygenase-2 inhibition combined with thromboxane receptor antagonism
    • Egan KM, Wang M, Lucitt MB et al (2005) Cyclooxygenases, thromboxane, and atherosclerosis: plaque destabilization by cyclooxygenase-2 inhibition combined with thromboxane receptor antagonism. Circulation 111: 334-342.
    • (2005) Circulation , vol.111 , pp. 334-342
    • Egan, K.M.1    Wang, M.2    Lucitt, M.B.3
  • 25
    • 0036098197 scopus 로고    scopus 로고
    • High glucose via peroxynitrite causes tyrosine nitration and inactivation of prostacyclin synthase that is associated with thromboxane/prostaglandin H2 receptor-mediated apoptosis and adhesion molecule expression in cultured human aortic endothelial cells
    • Zou MH, Shi C, Cohen RA (2002) High glucose via peroxynitrite causes tyrosine nitration and inactivation of prostacyclin synthase that is associated with thromboxane/prostaglandin H2 receptor-mediated apoptosis and adhesion molecule expression in cultured human aortic endothelial cells. Diabetes 51: 198-203.
    • (2002) Diabetes , vol.51 , pp. 198-203
    • Zou, M.H.1    Shi, C.2    Cohen, R.A.3
  • 26
    • 4944241267 scopus 로고    scopus 로고
    • 2 synthase and receptor, reduces 2-year mortality in diabetics with peripheral arterial disease: the DAVID study
    • 2 synthase and receptor, reduces 2-year mortality in diabetics with peripheral arterial disease: the DAVID study. Eur Heart J 25: 1845-1852.
    • (2004) Eur Heart J , vol.25 , pp. 1845-1852
    • Neri Serneri, G.G.1    Coccheri, S.2    Marubini, E.3    Violi, F.4
  • 27
    • 34547332061 scopus 로고    scopus 로고
    • A critical review of antiplatelet treatment in peripheral arterial disease
    • Violi F, Hiatt W (2007) A critical review of antiplatelet treatment in peripheral arterial disease. Intern Emerg Med 2: 84-87.
    • (2007) Intern Emerg Med , vol.2 , pp. 84-87
    • Violi, F.1    Hiatt, W.2
  • 28
    • 0030754003 scopus 로고    scopus 로고
    • Diabetes mellitus, hypercholesterolemia, and hypertension but not vascular disease per se are associated with persistent platelet activation in vivo. Evidence derived from the study of peripheral arterial disease
    • Davì G, Gresele P, Violi F et al (1997) Diabetes mellitus, hypercholesterolemia, and hypertension but not vascular disease per se are associated with persistent platelet activation in vivo. Evidence derived from the study of peripheral arterial disease. Circulation 96: 69-75.
    • (1997) Circulation , vol.96 , pp. 69-75
    • Davì, G.1    Gresele, P.2    Violi, F.3
  • 29
    • 0037454139 scopus 로고    scopus 로고
    • Acute, short-term hyperglycemia enhances shear stress-induced platelet activation in patients with type II diabetes mellitus
    • Gresele P, Guglielmini G, De Angelis M et al (2003) Acute, short-term hyperglycemia enhances shear stress-induced platelet activation in patients with type II diabetes mellitus. J Am Coll Cardiol 41: 1013-1020.
    • (2003) J Am Coll Cardiol , vol.41 , pp. 1013-1020
    • Gresele, P.1    Guglielmini, G.2    de Angelis, M.3
  • 31
    • 15044352193 scopus 로고    scopus 로고
    • Isoprostane formation and inhibition in atherothrombosis
    • Patrono C, Falco A, Davì G (2005) Isoprostane formation and inhibition in atherothrombosis. Curr Opin Pharmacol 5: 198-203.
    • (2005) Curr Opin Pharmacol , vol.5 , pp. 198-203
    • Patrono, C.1    Falco, A.2    Davì, G.3
  • 32
    • 26244441533 scopus 로고    scopus 로고
    • Oxidant stress, inflammation and atherogenesis
    • Davì G, Falco A (2005) Oxidant stress, inflammation and atherogenesis. Lupus 14: 760-764.
    • (2005) Lupus , vol.14 , pp. 760-764
    • Davì, G.1    Falco, A.2
  • 33
    • 0032905015 scopus 로고    scopus 로고
    • In vivo formation of 8-iso-prostaglandinF2alpha and platelet activation in diabetes mellitus: effects of improved metabolic control and vitamin E supplementation
    • Davì G, Ciabattoni G, Consoli A et al (1999) In vivo formation of 8-iso-prostaglandinF2alpha and platelet activation in diabetes mellitus: effects of improved metabolic control and vitamin E supplementation. Circulation 99: 224-229.
    • (1999) Circulation , vol.99 , pp. 224-229
    • Davì, G.1    Ciabattoni, G.2    Consoli, A.3
  • 35
    • 34447331279 scopus 로고    scopus 로고
    • Soluble RAGE in type 2 diabetes: association with oxidative stress
    • Devangelio E, Santilli F, Formoso G et al (2007) Soluble RAGE in type 2 diabetes: association with oxidative stress. Free Radic Biol Med 43: 511-518.
    • (2007) Free Radic Biol Med , vol.43 , pp. 511-518
    • Devangelio, E.1    Santilli, F.2    Formoso, G.3
  • 36
    • 30344483664 scopus 로고    scopus 로고
    • Thromboxane-dependent CD40 ligand release in type 2 diabetes mellitus
    • Santilli F, Davì G, Consoli A et al (2006) Thromboxane-dependent CD40 ligand release in type 2 diabetes mellitus. J Am Coll Cardiol 47: 391-397.
    • (2006) J Am Coll Cardiol , vol.47 , pp. 391-397
    • Santilli, F.1    Davì, G.2    Consoli, A.3
  • 37
    • 0022970057 scopus 로고
    • Trial of repeated low-dose aspirin in diabetic angiopathy
    • Di Minno G, Silver MJ, Cerbone AM, Murphy S (1986) Trial of repeated low-dose aspirin in diabetic angiopathy. Blood 68: 886-891.
    • (1986) Blood , vol.68 , pp. 886-891
    • Di Minno, G.1    Silver, M.J.2    Cerbone, A.M.3    Murphy, S.4
  • 38
    • 0035833502 scopus 로고    scopus 로고
    • The coxibs, selective inhibitors of cyclooxygenase-2
    • FitzGerald GA, Patrono C (2001) The coxibs, selective inhibitors of cyclooxygenase-2. N Engl J Med 345: 433-442.
    • (2001) N Engl J Med , vol.345 , pp. 433-442
    • Fitzgerald, G.A.1    Patrono, C.2
  • 39
    • 15044348667 scopus 로고    scopus 로고
    • Increased protein glycation in diabetes mellitus is associated with decreased aspirin-mediated protein acetylation and reduced sensitivity of blood platelets to aspirin
    • Watala C, Pluta J, Golanski J et al (2005) Increased protein glycation in diabetes mellitus is associated with decreased aspirin-mediated protein acetylation and reduced sensitivity of blood platelets to aspirin. J Mol Med 83: 148-158.
    • (2005) J Mol Med , vol.83 , pp. 148-158
    • Watala, C.1    Pluta, J.2    Golanski, J.3
  • 40
    • 75149180515 scopus 로고    scopus 로고
    • Standards of medical care in diabetes
    • American Diabetes Association
    • American Diabetes Association (2010) Standards of medical care in diabetes. Diabetes Care 33(Suppl): S11-61.
    • (2010) Diabetes Care , vol.33 , Issue.SUPPL. , pp. 11-61
  • 41
    • 0037065502 scopus 로고    scopus 로고
    • Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients
    • Antithrombotic Trialists' Collaboration
    • Antithrombotic Trialists' Collaboration (2002) Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients. BMJ 324: 71-86.
    • (2002) BMJ , vol.324 , pp. 71-86
  • 42
    • 71749088596 scopus 로고    scopus 로고
    • Aspirin for primary prevention of vascular disease in people with diabetes
    • Haynes R, Bowman L, Armitage J (2009) Aspirin for primary prevention of vascular disease in people with diabetes. BMJ 339: 1210-1211.
    • (2009) Bmj , vol.339 , pp. 1210-1211
    • Haynes, R.1    Bowman, L.2    Armitage, J.3
  • 43
    • 28244447830 scopus 로고    scopus 로고
    • Determinants of the interindividual variability in response to antiplatelet drugs
    • Rocca B, Patrono C (2005) Determinants of the interindividual variability in response to antiplatelet drugs. J Thromb Haemost 3: 1597-1602.
    • (2005) J Thromb Haemost , vol.3 , pp. 1597-1602
    • Rocca, B.1    Patrono, C.2
  • 44
    • 29244467682 scopus 로고    scopus 로고
    • Insulin therapy is associated with platelet dysfunction in patients with type 2 diabetes mellitus on dual oral antiplatelet treatment
    • Angiolillo DJ, Bernardo E, Ramírez C et al (2006) Insulin therapy is associated with platelet dysfunction in patients with type 2 diabetes mellitus on dual oral antiplatelet treatment. Am J Cardiol 97: 38-43.
    • (2006) Am J Cardiol , vol.97 , pp. 38-43
    • Angiolillo, D.J.1    Bernardo, E.2    Ramírez, C.3
  • 45
    • 70350056868 scopus 로고    scopus 로고
    • The relation between platelet reactivity and glycemic control in diabetic patients with cardiovascular disease on maintenance aspirin and clopidogrel therapy
    • Singla A, Antonino MJ, Bliden KP, Tantry US, Gurbel PA (2009) The relation between platelet reactivity and glycemic control in diabetic patients with cardiovascular disease on maintenance aspirin and clopidogrel therapy. Am Heart J 158: 784. e1-784. e6.
    • (2009) Am Heart J , vol.158 , pp. 1-6
    • Singla, A.1    Antonino, M.J.2    Bliden, K.P.3    Tantry, U.S.4    Gurbel, P.A.5
  • 46
    • 36849082996 scopus 로고    scopus 로고
    • The effect of aspirin dosing on platelet function in diabetic and nondiabetic patients: an analysis from the aspirin-induced platelet effect (ASPECT) study
    • Di Chiara J, Bliden KP, Tantry US et al (2007) The effect of aspirin dosing on platelet function in diabetic and nondiabetic patients: an analysis from the aspirin-induced platelet effect (ASPECT) study. Diabetes 56: 3014-3019.
    • (2007) Diabetes , vol.56 , pp. 3014-3019
    • Di Chiara, J.1    Bliden, K.P.2    Tantry, U.S.3
  • 47
    • 60049093774 scopus 로고    scopus 로고
    • Platelet cyclooxygenase inhibition by low-dose aspirin is not reflected consistently by platelet function assays: implications for aspirin, resistance
    • Santilli F, Rocca B, De Cristofaro R et al (2009) Platelet cyclooxygenase inhibition by low-dose aspirin is not reflected consistently by platelet function assays: implications for aspirin "resistance". J Am Coll Cardiol 53: 667-677.
    • (2009) J Am Coll Cardiol , vol.53 , pp. 667-677
    • Santilli, F.1    Rocca, B.2    de Cristofaro, R.3
  • 48
    • 0031940450 scopus 로고    scopus 로고
    • Long-term treatment with the dual antithromboxane agent picotamide decreases microalbuminuria in normotensive type 2 diabetic patients
    • Giustina A, Perini P, Desenzani P et al (1998) Long-term treatment with the dual antithromboxane agent picotamide decreases microalbuminuria in normotensive type 2 diabetic patients. Diabetes 47: 423-430.
    • (1998) Diabetes , vol.47 , pp. 423-430
    • Giustina, A.1    Perini, P.2    Desenzani, P.3
  • 50
    • 34247574729 scopus 로고    scopus 로고
    • Reticulated platelets and uninhibited COX-1 and COX-2 decrease the antiplatelet effects of aspirin
    • Guthikonda S, Lev EI, Patel R et al (2007) Reticulated platelets and uninhibited COX-1 and COX-2 decrease the antiplatelet effects of aspirin. J Thromb Haemost 5: 490-496.
    • (2007) J Thromb Haemost , vol.5 , pp. 490-496
    • Guthikonda, S.1    Lev, E.I.2    Patel, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.