Thrombin generation test: Establishment of reference values according to age and tissue factor concentration is essential before implementation into the laboratory;Test de génération de thrombine: Importance d'établir les valeurs de référence en fonction de l'âge et des concentrations en facteur tissulaire avant l'implémentation au laboratoire

Revue Medicale de Bruxelles

Volumn 32, Issue 2, 2011, Pages 69-73

  Filippin, L ^a   Debaugnies, F ^a   Noubouossie D ^a   Le P Q ^b   Ferster, A ^b   Demulder, A ^a  

^a BRUGMANN UNIVERSITY HOSPITAL   (Belgium)

^b HOP UNIV DES ENFANTS REINE FABIOLA   (Belgium)

Author keywords

Calibrated and automated thrombinography (CAT); Coagulation laboratory; Coagulation tests; Haemostasis reference values; Thrombin generation

Indexed keywords

THROMBIN; THROMBOPLASTIN;

AGE; ARTICLE; BLEEDING; BLOOD CLOTTING; CALIBRATION; HEMOSTASIS; HUMAN; LABORATORY TEST; PLASMA; REFERENCE VALUE; THROMBIN TIME; THROMBOCYTE; THROMBOSIS;

ADOLESCENT; ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; BLOOD COAGULATION TESTS; CHILD; CHILD, PRESCHOOL; HUMANS; INFANT; LABORATORIES; MIDDLE AGED; REFERENCE VALUES; THROMBIN; THROMBOPLASTIN; YOUNG ADULT;

EID: 79956295880     PISSN: 00353639     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Hemker HC, Giesen P, Al Dieri R et al. : The calibrated automated thrombogram (CAT) : a universal routine test for hyper- and hypocoagulability. Pathophysiol Haemost Thromb 2002 ; 32 : 249-53 (Pubitemid 37490547)
2. Lecompte T, Wahl D, Régnault V : Thrombinographie. Hématologie 2006 ; 12 : 115-27 (Pubitemid 43835439)
3. Gerotziafas GT : Le test de génération de thrombine. Un test utile pour la recherche et nécessaire pour une exploration moderne de l'hémostase. Bio Tribune Magazine 2007 ; 24 : 37-43
4. Haidl H, Cimenti C, Leschnik B, Zach D, Muntean W : Age-dependency of thrombin generation measured by means of calibrated automated thrombography (CAT). Thromb Haemost 2006 ; 95 : 772-5
5. Devreese K, Wijns W, Combes I, Van Kerckhoven S, Hoylaerts MF : Thrombin generation in plasma of healthy adults and children : Chromogenic versus fluorogenic thrombogram analysis. Thromb Haemost 2007 ; 98 : 600-13
6. Chantarangkul V, Clerici M, Bressi C, Giesen PL, Tripodi A : Thrombin generation assessed as endogenous thrombin potential in patients with hyper- or hypo-coagulability. Haematologica 2003 ; 88 : 547-54 (Pubitemid 36648444)
7. Andrew M, Vegh P, Johnston M : Maturation of the hemostatic system during childhood. Blood 1992 ; 80 : 1998-2005
8. Butenas S, van't Veer C, Mann KG : " Normal " thrombin generation. Blood 1999 ; 94 : 2169-78
9. Mann KG, Brummel K, Butenas S : What is all that thrombin for ? Thromb Haemost 2003 ; 1 : 1504-14
10. Spronk H, Dielis A, Panova-Noeva M et al. : Monitoring thrombin generation : Is addition of corn trypsin inhibitor needed ? Thromb Haemost 2009 ; 101 : 1156-62
11. Berntorp E, Salvagno GL : Standardization and clinical utility of thrombin-generation assays. Semin Thromb Hemost 2008 ; 34 : 670-82
12. Gerotziafas GT, Depasse F, Busson J, Leflem L, Elalamy L, Samama M : Towards a standardization of thrombin generation assessment : the influence of tissue factor, platelets and phospholipids concentration on the normal values of Thrombogram-Thrombinoscope assay. Thrombosis J 2005 ; 3 : 16