Biogenic amines and their metabolites are differentially affected in the Mecp2-deficient mouse brain

BMC Neuroscience

Volumn 12, Issue , 2011, Pages

  Panayotis, Nicolas ^a,b   Ghata, Adeline ^a,b   Villard, Laurent ^a,b   Roux, Jean Christophe ^a,b  

^a INSERM   (France)

^b AIX MARSEILLE UNIVERSITY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

5 HYDROXYINDOLEACETIC ACID; DIHYDROXYPHENYLACETIC ACID; DOPAMINE; HOMOVANILLIC ACID; METHYL CPG BINDING PROTEIN 2; NORADRENALIN; SEROTONIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; BRAIN CORTEX; BRAIN REGION; BRAIN STEM; CAUDATE NUCLEUS; CONTROLLED STUDY; DISEASE COURSE; DOPAMINE BRAIN LEVEL; DOPAMINE METABOLISM; DOPAMINERGIC SYSTEM; ELECTROCHEMICAL DETECTION; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYPOTHALAMUS; MESENCEPHALON; MOUSE; NONHUMAN; NORADRENALIN BRAIN LEVEL; PONS; PONTOBULBAR REGION; PROTEIN STABILITY; PUTAMEN; RETT SYNDROME; SEROTONIN BRAIN LEVEL; STRIATONIGRAL DEGENERATION; AGE; ANIMAL; GENETICS; MALE; METABOLISM; MOUSE MUTANT;

AGE FACTORS; ANIMALS; BRAIN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOPAMINE; MALE; METHYL-CPG-BINDING PROTEIN 2; MICE; MICE, KNOCKOUT; NOREPINEPHRINE; SEROTONIN;

EID: 79956280638     PISSN: None     EISSN: 14712202     Source Type: Journal    
DOI: 10.1186/1471-2202-12-47     Document Type: Article

References (40)

1. Amir RE, Van den Veyver IB, Wan M, Tran CQ, Francke U, Zoghbi HY. Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2. Nat Genet 1999, 23(2):185-188. 10.1038/13810, 10508514.
2. Laurvick CL, de Klerk N, Bower C, Christodoulou J, Ravine D, Ellaway C, Williamson S, Leonard H. Rett syndrome in Australia: a review of the epidemiology. J Pediatr 2006, 148(3):347-352. 10.1016/j.jpeds.2005.10.037, 16615965.
3. Chahrour M, Zoghbi HY. The story of Rett syndrome: from clinic to neurobiology. Neuron 2007, 56(3):422-437. 10.1016/j.neuron.2007.10.001, 17988628.
4. Hagberg B, Hanefeld F, Percy A, Skjeldal O. An update on clinically applicable diagnostic criteria in Rett syndrome. Comments to Rett Syndrome Clinical Criteria Consensus Panel Satellite to European Paediatric Neurology Society Meeting, Baden Baden, Germany, 11 September 2001. Eur J Paediatr Neurol 2002, 6(5):293-297. 10.1053/ejpn.2002.0612, 12378695.
5. Neul JL, Kaufmann WE, Glaze DG, Christodoulou J, Clarke AJ, Bahi-Buisson N, Leonard H, Bailey ME, Schanen NC, Zappella M, Renieri A, Huppke P, Percy AK. Rett syndrome: revised diagnostic criteria and nomenclature. Ann Neurol 2010, 68(6):944-950. 10.1002/ana.22124, 21154482.
6. Ide S, Itoh M, Goto Y. Defect in normal developmental increase of the brain biogenic amine concentrations in the mecp2-null mouse. Neurosci Lett 2005, 386(1):14-17. 10.1016/j.neulet.2005.05.056, 15975715.
7. Samaco RC, Mandel-Brehm C, Chao HT, Ward CS, Fyffe-Maricich SL, Ren J, Hyland K, Thaller C, Maricich SM, Humphreys P, Greer J, Percy A, Glaze D, Zoghbi HY, Neul JL. Loss of MeCP2 in aminergic neurons causes cell-autonomous defects in neurotransmitter synthesis and specific behavioral abnormalities. Proc Natl Acad Sci USA 2009,
8. Roux JC, Villard L. Biogenic Amines in Rett Syndrome: The Usual Suspects. Behav Genet 2009, 40:59-75.
9. Taneja P, Ogier M, Brooks-Harris G, Schmid DA, Katz DM, Nelson SB. Pathophysiology of locus ceruleus neurons in a mouse model of Rett syndrome. J Neurosci 2009, 29(39):12187-12195. 10.1523/JNEUROSCI.3156-09.2009, 2846656, 19793977.
10. Isoda K, Morimoto M, Matsui F, Hasegawa T, Tozawa T, Morioka S, Chiyonobu T, Nishimura A, Yoshimoto K, Hosoi H. Postnatal changes in serotonergic innervation to the hippocampus of methyl-CpG-binding protein 2-null mice. Neuroscience 2010, 165(4):1254-1260. 10.1016/j.neuroscience.2009.11.036, 19932741.
11. Santos M, Summavielle T, Teixeira-Castro A, Silva-Fernandes A, Duarte-Silva S, Marques F, Martins L, Dierssen M, Oliveira P, Sousa N, Maciel P. Monoamine deficits in the brain of methyl-CpG binding protein 2 null mice suggest the involvement of the cerebral cortex in early stages of Rett syndrome. Neuroscience 2010, 170(2):453-467. 10.1016/j.neuroscience.2010.07.010, 20633611.
12. Panayotis N, Pratte M, Borges-Correia A, Ghata A, Villard L, Roux JC. Morphological and functional alterations in the substantia nigra pars compacta of the Mecp2-null mouse. Neurobiol Dis 2011, 41(2):385-397. 10.1016/j.nbd.2010.10.006, 20951208.
13. Fyffe SL, Neul JL, Samaco RC, Chao HT, Ben-Shachar S, Moretti P, McGill BE, Goulding EH, Sullivan E, Tecott LH, Zoghbi HY. Deletion of Mecp2 in Sim1-expressing neurons reveals a critical role for MeCP2 in feeding behavior, aggression, and the response to stress. Neuron 2008, 59(6):947-958. 10.1016/j.neuron.2008.07.030, 2597031, 18817733.
14. Berridge CW. Neural substrates of psychostimulant-induced arousal. Neuropsychopharmacology 2006, 31(11):2332-2340. 10.1038/sj.npp.1301159, 16855535.
15. Khan AM, Ponzio TA, Sanchez-Watts G, Stanley BG, Hatton GI, Watts AG. Catecholaminergic control of mitogen-activated protein kinase signaling in paraventricular neuroendocrine neurons in vivo and in vitro: a proposed role during glycemic challenges. J Neurosci 2007, 27(27):7344-7360. 10.1523/JNEUROSCI.0873-07.2007, 17611287.
16. Rodriguez Fermepin M, Trinchero M, Minetto J, Beltran A, Fernandez BE. Brain derived neurotrophic factor and neurotrophin-4 employ different intracellular pathways to modulate norepinephrine uptake and release in rat hypothalamus. Neuropeptides 2009, 43(4):275-282. 10.1016/j.npep.2009.06.001, 19576631.
17. Kutlu S, Aydin M, Alcin E, Ozcan M, Bakos J, Jezova D, Yilmaz B. Leptin modulates noradrenaline release in the paraventricular nucleus and plasma oxytocin levels in female rats: a microdialysis study. Brain Res 2010, 1317:87-91.
18. Dani VS, Chang Q, Maffei A, Turrigiano GG, Jaenisch R, Nelson SB. Reduced cortical activity due to a shift in the balance between excitation and inhibition in a mouse model of Rett syndrome. Proc Natl Acad Sci USA 2005, 102(35):12560-12565. 10.1073/pnas.0506071102, 1194957, 16116096.
19. Tropea D, Giacometti E, Wilson NR, Beard C, McCurry C, Fu DD, Flannery R, Jaenisch R, Sur M. Partial reversal of Rett Syndrome-like symptoms in MeCP2 mutant mice. Proc Natl Acad Sci USA 2009, 106(6):2029-2034. 10.1073/pnas.0812394106, 2644158, 19208815.
20. Chang Q, Khare G, Dani V, Nelson S, Jaenisch R. The disease progression of Mecp2 mutant mice is affected by the level of BDNF expression. Neuron 2006, 49(3):341-348. 10.1016/j.neuron.2005.12.027, 16446138.
21. Poo MM. Neurotrophins as synaptic modulators. Nat Rev Neurosci 2001, 2(1):24-32. 10.1038/35049004, 11253356.
22. Balkowiec A, Katz DM. Brain-derived neurotrophic factor is required for normal development of the central respiratory rhythm in mice. J Physiol 1998, 510(Pt 2):527-533. 2231051, 9706001.
23. Erickson JT, Conover JC, Borday V, Champagnat J, Barbacid M, Yancopoulos G, Katz DM. Mice lacking brain-derived neurotrophic factor exhibit visceral sensory neuron losses distinct from mice lacking NT4 and display a severe developmental deficit in control of breathing. J Neurosci 1996, 16:5361-71.
24. Viemari JC, Roux JC, Tryba AK, Saywell V, Burnet H, Pena F, Zanella S, Bevengut M, Barthelemy-Requin M, Herzing LB, Moncla A, Mancini J, Ramirez JM, Villard L, Hilaire G. Mecp2 deficiency disrupts norepinephrine and respiratory systems in mice. J Neurosci 2005, 25(50):11521-11530. 10.1523/JNEUROSCI.4373-05.2005, 16354910.
25. Oo TF, Marchionini DM, Yarygina O, O'Leary PD, Hughes RA, Kholodilov N, Burke RE. Brain-derived neurotrophic factor regulates early postnatal developmental cell death of dopamine neurons of the substantia nigra in vivo. Mol Cell Neurosci 2009, 41(4):440-447. 10.1016/j.mcn.2009.04.009, 2743455, 19409492.
26. Gu Q. Neuromodulatory transmitter systems in the cortex and their role in cortical plasticity. Neuroscience 2002, 111(4):815-835. 10.1016/S0306-4522(02)00026-X, 12031406.
27. Calfa G, Percy AK, Pozzo-Miller L. Experimental models of Rett syndrome based on Mecp2 dysfunction. Exp Biol Med (Maywood) 2011, 236(1):3-19.
28. Yadav VK, Oury F, Suda N, Liu ZW, Gao XB, Confavreux C, Klemenhagen KC, Tanaka KF, Gingrich JA, Guo XE, Tecott LH, Mann JJ, Hen R, Horvath TL, Karsenty G. A serotonin-dependent mechanism explains the leptin regulation of bone mass, appetite, and energy expenditure. Cell 2009, 138(5):976-989. 10.1016/j.cell.2009.06.051, 2768582, 19737523.
29. Guy J, Hendrich B, Holmes M, Martin JE, Bird A. A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome. Nat Genet 2001, 27(3):322-326. 10.1038/85899, 11242117.
30. Chen RZ, Akbarian S, Tudor M, Jaenisch R. Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice. Nat Genet 2001, 27(3):327-331. 10.1038/85906, 11242118.
31. Katz DM, Dutschmann M, Ramirez JM, Hilaire G. Breathing disorders in Rett syndrome: progressive neurochemical dysfunction in the respiratory network after birth. Respir Physiol Neurobiol 2009, 168(1-2):101-108. 10.1016/j.resp.2009.04.017, 2758855, 19394452.
32. Lioy DT, Wu WW, Bissonnette JM. Autonomic dysfunction with mutations in the gene that encodes methyl-CpG-binding protein 2: Insights into Rett syndrome. Auton Neurosci 2011,
33. Bonham AC. Neurotransmitters in the CNS control of breathing. Respir Physiol 1995, 101(3):219-230. 10.1016/0034-5687(95)00045-F, 8606995.
34. Pratte M, Panayotis N, Gatha A, Villard L, Roux JC. Progressive motor and respiratory metabolism deficits in post-weaning Mecp2-null male mice. Behav Brain Res 2011, 216(1):313-20. 10.1016/j.bbr.2010.08.011, 20713094.
35. Tassin JP. Uncoupling between noradrenergic and serotonergic neurons as a molecular basis of stable changes in behavior induced by repeated drugs of abuse. Biochem Pharmacol 2008, 75(1):85-97. 10.1016/j.bcp.2007.06.038, 17686465.
36. Sara SJ. The locus coeruleus and noradrenergic modulation of cognition. Nat Rev Neurosci 2009, 10(3):211-223. 10.1038/nrn2573, 19190638.
37. Guevara BH, Torrico F, Hoffmann IS, Cubeddu LX. Lesion of caudate-putamen interneurons with kainic acid alters dopamine and serotonin metabolism in the olfactory tubercle of the rat. Cell Mol Neurobiol 2002, 22(5-6):835-844.
38. Youdim MB, Arraf Z. Prevention of MPTP (N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) dopaminergic neurotoxicity in mice by chronic lithium: involvements of Bcl-2 and Bax. Neuropharmacology 2004, 46(8):1130-1140. 10.1016/j.neuropharm.2004.02.005, 15111020.
39. Paxinos G, Franklin K. The Mouse Brain in Stereotaxic Coordinates. 2001, Academic, San Diego.
40. Roux JC, Mamet J, Perrin D, Peyronnet J, Royer C, Cottet-Emard JM, Pequignot JM, Dalmaz Y. Neurochemical development of the brainstem catecholaminergic cell groups in rat. J Neural Transm 2003, 110(1):51-65.