Research progress on myofibroblasts: Their sources and roles in liver fibrogensis

Chinese Pharmacological Bulletin

Volumn 27, Issue 3, 2011, Pages 297-300

  Kong, De Song ^a   Zheng, Shi Zhong ^a,b   Lu, Yin ^a,b   Wang, Ai Yun ^a,b  

^a NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

^b Key Laboratory for Modern Research of Traditional Chinese Medical Formulae of Jiangsu   (China)

Author keywords

Bone marrow stem cells; Epithelial mesenchymal transition; Hepatic stellate cell; Liver fibrosis; Myofibroblasts; Pe; Ripheral blood cell

Indexed keywords

ARTICLE; BONE MARROW; CELL ACTIVATION; CELL TRANSFORMATION; DISEASE COURSE; EPITHELIUM CELL; FIBROGENESIS; LIVER CELL; LIVER FIBROSIS; MESENCHYME CELL; MYOFIBROBLAST; PATHOGENESIS; STELLATE CELL;

EID: 79956277944     PISSN: 10011978     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Anthony B, Allen J T, Li Y S, McManus D P. Hepatic stellate cells and parasite-induced liver fibrosis[J]. Parasi Vectors, 2010,3(1):60.
2. Pilling D, Fan T, Huang D, et al. Identification of markers that distinguish monocyte-derived fibrocytes from monocytes, macrophages, and fibroblasts[J]. PLoS One, 2009,4(10):e7475.
3. Yang Y, Yang S, Chen M, et al. Compound Astragalus and Salvia miltiorrhiza extract exerts anti-fibrosis by mediating TGF-beta/Smad signaling in myofibroblasts[J]. Ethnopharmacol, 2008,118(2):264-70.
4. Borkham-Kamphorst E, Herrmann J, Stoll D, et al. Dominant-negative soluble PDGF-beta receptor inhibits hepatic stellate cell activation and attenuates liver fibrosis[J]. Lab Invest, 2004,84(6):766-77.
5. Varela-Rey M, Fontan-Gabas L, Blanco P, et al. Glutathione depletion is involved in the inhibition of procollagen alpha1 (I) mRNA levels caused by TNF-alpha on hepatic stellate cells[J]. Cytokine, 2007,37(3):212-7.
6. Niu L W, Cao Q, Li J, et al. JAK/STAT pathway mediates leptin-induced I collagen mRNA expression in human hepatic stellate cells[J]. Chin Pharmacol Bull, 2007,23(10):1280-5.
7. Wang B B, Cheng J Y, Gao H H, et al. Hepatic stellate cells in inflammation-fibrosis-carcinoma axis[J]. Anal Rec (Hoboken), 2010,293(9):1492-6.
8. Huang Y, Huang C, Li J. Effect of cytokines secreted from Kupffer cell on HSC proliferation, apoptosis in hepatic fibrosis process[J]. Chin Pharmacol Bull, 2010,26(1):9-13.
9. He W Y, Liu S X, Jiang H Q. Rat bone marrow mesenchymal stem cells differentiate into hepatocyte-like cells in vitro[J]. World Chin J Digestol, 2008,16(22):2464-9.
10. Asawa S, Saito T, Satoh A, et al. Participation of bone marrow cells in biliary fibrosis after bile duct ligation[J]. Gastroenterol Hepatol, 2007,22(11):2001-8. (Pubitemid 47525070)
11. Russo F P, Alison M R, Bigger B W, et al. The bone marrow functionally contributes to liver fibrosis[J]. Gastroenterology, 2006,130(6):1807-21. (Pubitemid 43668827)
12. Baba S, Fujii H, Hirose T, et al. Commitment of bone marrow cells to hepatic stellate cells in mouse[J]. Hepatol, 2004,40(2):255-60.
13. Kisseleva T, Uchinami H, Feirt N, et al. Bone marrow-derived fibrocytes participate in pathogenesis of liver fibrosis[J]. Hepatol, 2006,45(3):429-38. (Pubitemid 44142115)
14. Wu X Z, Chen D. Origin of hepatocellular carcinoma: role of stem cells[J]. Gastroenterol Hepatol, 2006,21(7):1093-8.
15. Xu S Y, Li J, Geng M Y. The signal transduction and drug development of epithelial-mesenchymal transition[J]. Chin Pharmacol Bull, 2008,24(9):1131-4.
16. Neil J R, Johnson K M, Nemenoff R A, et al. Cox-2 inactivates Smad signaling and enhances EMT stimulated by TGF-beta through a PGE2-dependent mechanisms[J]. Carcinogenesis, 2008,29(11):2227-35.
17. Yamashita M, Fatyol K, Jin C, et al. TRAF6 mediates Smad-independent activation of JNK and p38 by TGF-beta[J]. Mol Cell, 2008,31(6):918-24.
18. Peinado H, Quintanilla M, Cano A. Transforming growth factor beta-1 induces snail transcription factor in epithelial cell lines: mechanisms for epithelial mesenchymal transitions[J]. Biol Chem, 2003,278(23):21113-23. (Pubitemid 36806424)
19. Kinoshita K, Iimuro Y, Otogawa K, et al. Adenovirus-mediated expression of BMP-7 suppresses the development of liver fibrosis in rats[J]. Gut, 2007,56(5):706-14. (Pubitemid 46662939)
20. Zhou Y, Jia X, Wang G, et al. PI-3 K/AKT and ERK signaling pathways mediate leptin-induced inhibition of PPAR gamma gene expression in primary rat hepatic stellate cells[J]. Mol Cell Biochem, 2009,325(1-2):131-9.
21. Radisky D C, Kenny P A, Bissell M J. Fibrosis and cancer: do myofibroblasts come also from epithelial cells via EMT[J]? Cell Biochem, 2007,101(4):830-9. (Pubitemid 47040865)
22. Kuroda N, Guo L, Miyazaki E, et al. The appearance of myofibroblasts and the disappearance of CD34-positive stromal cells in the area adjacent to xanthogranulomatous foci of chronic cholecystitis [J]. Histol Histopathol, 2005,20(1):127-33. (Pubitemid 40028991)
23. Bucala R, Spiegel L A, Chesney J, et al. Circulating fibrocytes define a new leukocyte subpopulation that mediates tissue repair [J]. Mol Med, 1994,1(1):71-81.
24. Abe R, Donnelly S C, Peng T, et al. Peripheral blood fibrocytes: differentiation pathway and migration to wound sites[J]. Immunol, 2001,166(12):7556-62. (Pubitemid 32525636)
25. Shao D D, Suresh R, Vakil V, Gomer R H, et al. Pivotal advance: Th-1 cytokines inhibit, and Th-2 cytokines promote fibrocyte differentiation[J]. Leukoc Biol, 2008,83(6):1323-33. (Pubitemid 351960310)
26. Ruhnke M, Nussler A K, Ungefroren H, et al. Human monocyte-derived neohepatocytes: a promising alternative to primary human hepatocytes for autologous cell therapy[J]. Transplantation, 2005,79(9):1097-103. (Pubitemid 40664004)