Rapid vascularization of starch-poly(caprolactone) in vivo by outgrowth endothelial cells in co-culture with primary osteoblasts

Journal of Tissue Engineering and Regenerative Medicine

Volumn 5, Issue 6, 2011, Pages

  Ghanaati, Shahram ^a,b   Fuchs, Sabine ^a   Webber, Matthew J ^c   Orth, Carina ^a   Barbeck, Mike ^a   Gomes, Manuela E ^d   Reis, Rui L ^d   James Kirkpatrick, C ^a  

^a UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

^b GOETHE UNIVERSITY   (Germany)

^c Northwestern University   (United States)

^d UNIVERSITY OF MINHO   (Portugal)

Author keywords

Angiogenesis; Co culture; In vivo; Osteoblast; Outgrowth endothelial cell; Pericyte

Indexed keywords

CYTOLOGY; OSTEOBLASTS; SCAFFOLDS (BIOLOGY); STARCH; TISSUE;

ANGIOGENESIS; CO-CULTURES; ENDOTHELIAL-CELLS; IN-VIVO; OUTGROWTH ENDOTHELIAL CELL; PERICYTES; POLY(-CAPROLACTONE); PRIMARY OSTEOBLASTS; VASCULAR STRUCTURES; VASCULARIZATION;

ENDOTHELIAL CELLS;

BIOMATERIAL; POLYCAPROLACTONE; TISSUE SCAFFOLD;

ANGIOGENESIS; ANIMAL CELL; ARTICLE; COCULTURE; CONTROLLED STUDY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IMPLANTATION; IN VIVO STUDY; MOUSE; NONHUMAN; OSTEOBLAST; PARACRINE SIGNALING; PRIORITY JOURNAL; TISSUE ENGINEERING; VASCULARIZATION;

EID: 79956276005     PISSN: 19326254     EISSN: 19327005     Source Type: Journal    
DOI: 10.1002/term.373     Document Type: Article

References (26)

1. Au P, Daheron LM, Duda DG, et al. 2008; Differential in vivo potential of endothelial progenitor cells from human umbilical cord blood and adult peripheral blood to form functional long-lasting vessels. Blood 111(3): 1302-1305.
2. Brighton CT, Lorich DG, Kupcha R, et al. 1992; The pericyte as a possible osteoblast progenitor cell. Clin Orthop Relat Res 275: 287-299.
3. Carmeliet P. 2005; Angiogenesis in life, disease and medicine. Nature 438(7070): 932-936.
4. Doherty MJ, Ashton BA, Walsh S, et al. 1998; Vascular pericytes express osteogenic potential in vitro and in vivo. J Bone Miner Res 13(5): 828-838.
5. Folkman J. 2003; Fundamental concepts of the angiogenic process. Curr Mol Med 3(7): 643-651.
6. Fuchs S, Dohle E, Kolbe M, et al. 2009a; Outgrowth endothelial cells: sources, characteristics and potential applications in tissue engineering and regenerative medicine. Adv Biochem Eng Biotechnol (in press) [DOI: 10.1007/10-2009-65].
7. Fuchs S, Ghanaati S, Orth C, et al. 2009c; Contribution of outgrowth endothelial cells from human peripheral blood on in vivo vascularization of bone tissue engineered constructs based on starch polycaprolactone scaffolds. Biomaterials 30(4): 526-534.
8. Fuchs S, Hermanns MI, Kirkpatrick CJ. 2006b; Retention of a differentiated endothelial phenotype by outgrowth endothelial cells isolated from human peripheral blood and expanded in long-term cultures. Cell Tissue Res 326(1): 79-92.
9. Fuchs S, Hofmann A, Kirkpatrick CJ. 2007; Microvessel-like structures from outgrowth endothelial cells from human peripheral blood in two-dimensional and three-dimensional co-cultures with osteoblastic lineage cells. Tissue Eng 13(10): 2577-2588.
10. Fuchs S, Jiang X, Schmidt H, et al. 2009b; Dynamic processes involved in the pre-vascularization of silk fibroin constructs for bone regeneration using outgrowth endothelial cells. Biomaterials 30(7): 1329-1338.
11. Fuchs S, Motta A, Migliaresi C, et al. 2006a; Outgrowth endothelial cells isolated and expanded from human peripheral blood progenitor cells as a potential source of autologous cells for endothelialization of silk fibroin biomaterials. Biomaterials 27(31): 5399-5408.
12. Gerhardt H, Betsholtz C. 2003; Endothelial-pericyte interactions in angiogenesis. Cell Tissue Res 314(1): 15-23.
13. Ghanaati S, Orth C, Unger RE, et al. 2010; Fine-tuning scaffolds for tissue regeneration: effects of formic acid processing on tissue reaction to silk fibroin. J Tissue Eng Regen Med (in press) [DOI: 10.1002/term.257].
14. Ghanaati S, Webber MJ, Unger RE, et al. 2009; Dynamic in vivo biocompatibility of angiogenic peptide amphiphile nanofibers. Biomaterials 30(31): 6202-6212.
15. Gomes ME, Sikavitsas VI, Behravesh E, et al. 2003; Effect of flow perfusion on the osteogenic differentiation of bone marrow stromal cells cultured on starch-based three-dimensional scaffolds. J Biomed Mater Res A 67(1): 87-95.
16. Hofmann A, Konrad L, Gotzen L, et al. 2003; Bioengineered human bone tissue using autogenous osteoblasts cultured on different biomatrices. J Biomed Mater Res A 67(1): 191-199.
17. Melero-Martin JM, Khan ZA, Picard A, et al. 2007; In vivo vasculogenic potential of human blood-derived endothelial progenitor cells. Blood 109(11): 4761-4768.
18. Reilly TM, Seldes R, Luchetti W, et al. 1998; Similarities in the phenotypic expression of pericytes and bone cells. Clin Orthop Relat Res 346: 95-103.).
19. Santos MI, Fuchs S, Gomes ME, et al. 2007; Response of micro- and macrovascular endothelial cells to starch-based fiber meshes for bone tissue engineering. Biomaterials 28(2): 240-248.
20. Santos MI, Unger RE, Sousa RA, et al. 2009; Crosstalk between osteoblasts and endothelial cells co-cultured on a poly-caprolactone-starch scaffold and the in vitro development of vascularization. Biomaterials 30(26): 4407-4415.
21. Shepro D, Morel NM. 1993; Pericyte physiology. FASEB J 7(11): 1031-1038.
22. Silva EA, Kim ES, Kong HJ, et al. 2008; Material-based deployment enhances efficacy of endothelial progenitor cells. Proc Natl Acad Sci USA 105(38): 14347-14352.
23. Unger RE, Ghanaati S, Orth C, et al. 2010; The rapid anastomosis between prevascularized networks on silk fibroin scaffold generated in vitro with co-cultures of human microvascular enothelial and osteoblast cells and the host vasculature. Biomaterials 31(27): 6959-6967.
24. Unger RE, Peters K, Huang Q, et al. 2005; Vascularization and gene regulation of human endothelial cells growing on porous polyethersulfone (PES) hollow fiber membranes. Biomaterials 26(17): 3461-3469.
25. Unger RE, Peters K, Wolf M, et al. 2004; Endothelialization of a non-woven silk fibroin net for use in tissue engineering: growth and gene regulation of human endothelial cells. Biomaterials 25(21): 5137-5146.
26. Unger RE, Sartoris A, Peters K, et al. 2007; Tissue-like self-assembly in co-cultures of endothelial cells and osteoblasts and the formation of microcapillary-like structures on three-dimensional porous biomaterials. Biomaterials 28(27): 3965-3976.