SSH-BM-I, a tryptamine derivative, stimulates mineralization in terminal osteoblast differentiation but inhibits osteogenesis of pre-committed progenitor cells

Journal of Pharmacological Sciences

Volumn 116, Issue 1, 2011, Pages 63-72

  Mikami, Yoshikazu ^a   Somei, Masanori ^b   Tsuda, Hiromasa ^a  

^a NIHON UNIVERSITY   (Japan)

^b KANAZAWA UNIVERSITY   (Japan)

Author keywords

Mineralization; Osteoblast; SSH BM I; Tryptamine

Indexed keywords

1 BENZYL 2,4,6 TRIBROMOMELATONIN; ALKALINE PHOSPHATASE; BONE MORPHOGENETIC PROTEIN 2; BONE SIALOPROTEIN; CALCIUM ION; DEXAMETHASONE; MESSENGER RNA; OSTEOCALCIN; SMAD1 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; TRANSCRIPTION FACTOR OSTERIX; TRANSCRIPTION FACTOR RUNX2; TRYPTAMINE DERIVATIVE; UNCLASSIFIED DRUG;

ADIPOCYTE; ANIMAL CELL; ARTICLE; BONE DEVELOPMENT; BONE MINERALIZATION; CALCIUM TRANSPORT; CELL DIFFERENTIATION; CONTROLLED STUDY; DRUG MECHANISM; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; MARKER GENE; MESENCHYMAL STEM CELL; NONHUMAN; OSTEOBLAST; PROTEIN PHOSPHORYLATION; RAT; UPREGULATION;

EID: 79956222623     PISSN: 13478613     EISSN: 13478648     Source Type: Journal    
DOI: 10.1254/jphs.10329FP     Document Type: Article

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