메뉴 건너뛰기




Volumn 116, Issue 1, 2011, Pages 25-29

Novel situations of endothelial injury in stroke - Mechanisms of stroke and strategy of drug development: Intracranial bleeding associated with the treatment of ischemic stroke: Thrombolytic treatment of ischemia-affected endothelial cells with tissue-type plasminogen activator

Author keywords

Cerebral ischemia; Endothelial injury; Intracranial hemorrhage; Low density lipoprotein receptor related protein; Matrix metalloproteinase; Tissue type plasminogen activator

Indexed keywords

DISUFENTON SODIUM; FREE RADICAL; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; MATRIX METALLOPROTEINASE; NEUROPROTECTIVE AGENT; NORPHENAZONE; PLASMIN; RECEPTOR ASSOCIATED PROTEIN; STROMELYSIN; TISSUE PLASMINOGEN ACTIVATOR; UNCLASSIFIED DRUG;

EID: 79956198341     PISSN: 13478613     EISSN: 13478648     Source Type: Journal    
DOI: 10.1254/jphs.10R27FM     Document Type: Short Survey
Times cited : (23)

References (34)
  • 1
    • 0033933641 scopus 로고    scopus 로고
    • Thienopyridines or aspirin to prevent stroke and other serious vascular events in patients at high risk of vascular disease? A systematic review of the evidence from randomized trials
    • Hankey G, Sudlow C, David W. Thienopyridines or aspirin to prevent stroke and other serious vascular events in patients at high risk of vascular disease? A systematic review of the evidence from randomized trials. Stroke. 2000;31:1779-1784. (Pubitemid 30437537)
    • (2000) Stroke , vol.31 , Issue.7 , pp. 1779-1784
    • Hankey, G.J.1    Sudlow, C.L.M.2    Dunbabin, D.W.3
  • 2
    • 1642453780 scopus 로고    scopus 로고
    • Clinical impact of bleeding in patients taking oral anticoagulant therapy for venous thromboembolism: A meta-analysis
    • Linkins L, Choi P, Douketis J. Clinical impact of bleeding in patients taking oral anticoagulant therapy for venous thromboembolism: a meta-analysis. Ann Intern Med. 2003;139:893-900.
    • (2003) Ann Intern Med , vol.139 , pp. 893-900
    • Linkins, L.1    Choi, P.2    Douketis, J.3
  • 3
    • 0027505093 scopus 로고
    • Secondary prevention in non-rheumatic atrial fibrillation after transient ischaemic attack or minor stroke
    • European Atrial Fibrillation Trial (EAFT) Study Group
    • European Atrial Fibrillation Trial (EAFT) Study Group. Secondary prevention in non-rheumatic atrial fibrillation after transient ischaemic attack or minor stroke. Lancet. 1993;342:1255-1262.
    • (1993) Lancet , vol.342 , pp. 1255-1262
  • 4
    • 0021141996 scopus 로고
    • Immediate anticoagulation of embolic stroke: Brain hemorrhage and management options
    • Cerebral Embolism Study Group
    • Cerebral Embolism Study Group. Immediate anticoagulation of embolic stroke: brain hemorrhage and management options. Stroke. 1984;15:779-789.
    • (1984) Stroke , vol.15 , pp. 779-789
  • 5
    • 0030911057 scopus 로고    scopus 로고
    • The International Stroke Trial (IST): A randomized trial of aspirin, subcutaneous heparin, both, or neither among 19435 patients with acute ischaemic stroke
    • International Stroke Trial Collaborative Group
    • International Stroke Trial Collaborative Group. The International Stroke Trial (IST): a randomized trial of aspirin, subcutaneous heparin, both, or neither among 19435 patients with acute ischaemic stroke. Lancet. 1997;349:1569-1581.
    • (1997) Lancet , vol.349 , pp. 1569-1581
  • 6
    • 0034621003 scopus 로고    scopus 로고
    • Low molecular-weight heparin versus aspirin in patients with acute ischaemic stroke and atrial fibrillation: A double-blind randomised study
    • HAEST Study Group. Heparin in Acute Embolic Stroke Trial
    • Berge E, Abdelnoor M, Nakstad PH, Sandset PM. Low molecular-weight heparin versus aspirin in patients with acute ischaemic stroke and atrial fibrillation: a double-blind randomised study. HAEST Study Group. Heparin in Acute Embolic Stroke Trial. Lancet. 2000;355:1205-1210.
    • (2000) Lancet , vol.355 , pp. 1205-1210
    • Berge, E.1    Abdelnoor, M.2    Nakstad, P.H.3    Sandset, P.M.4
  • 7
    • 77956884231 scopus 로고    scopus 로고
    • Cilostazol for prevention of secondary stroke (CSPS 2): An aspirin-controlled, double-blind, randomised noninferiority trial
    • Shinohara Y, Katayama Y, Uchiyama S, Yamaguchi T, Handa S, Matsuoka K, et al. Cilostazol for prevention of secondary stroke (CSPS 2): an aspirin-controlled, double-blind, randomised noninferiority trial. Lancet Neurol. 2010;9:959-968.
    • (2010) Lancet Neurol , vol.9 , pp. 959-968
    • Shinohara, Y.1    Katayama, Y.2    Uchiyama, S.3    Yamaguchi, T.4    Handa, S.5    Matsuoka, K.6
  • 9
    • 0033486107 scopus 로고    scopus 로고
    • Intra-arterial prourokinase for acute ischemic stroke. The PROACT II study: A randomized controlled trial. Prolyse in Acute Cerebral Thromboembolism
    • Furlan A, Higashida R, Wechsler L, Gent M, Rowley H, Kase C, et al. Intra-arterial prourokinase for acute ischemic stroke. The PROACT II study: a randomized controlled trial. Prolyse in Acute Cerebral Thromboembolism. JAMA. 1999;282:2003-2011.
    • (1999) JAMA , vol.282 , pp. 2003-2011
    • Furlan, A.1    Higashida, R.2    Wechsler, L.3    Gent, M.4    Rowley, H.5    Kase, C.6
  • 10
    • 34848883164 scopus 로고    scopus 로고
    • Randomized trial of intraarterial infusion of urokinase within 6 hours of middle cerebral artery stroke: The middle cerebral artery embolism local fibrinolytic intervention trial (MELT) Japan
    • MELT Japan Study Group
    • Ogawa A, Mori E, Minematsu K, Taki W, Takahashi A, Nemoto S, et al. MELT Japan Study Group. Randomized trial of intraarterial infusion of urokinase within 6 hours of middle cerebral artery stroke: the middle cerebral artery embolism local fibrinolytic intervention trial (MELT) Japan. Stroke. 2007;38:2633-2639.
    • (2007) Stroke , vol.38 , pp. 2633-2639
    • Ogawa, A.1    Mori, E.2    Minematsu, K.3    Taki, W.4    Takahashi, A.5    Nemoto, S.6
  • 11
    • 1542315556 scopus 로고    scopus 로고
    • Association of outcome with early stroke treatment: Pooled analysis of ATLANTIS, ECASS, and NINDS rt-PA stroke trials
    • Hacke W, Donnan G, Fieschi C, Kaste M, von Kummer R, Broderick J, et al. Association of outcome with early stroke treatment: pooled analysis of ATLANTIS, ECASS, and NINDS rt-PA stroke trials. Lancet. 2004;363:768-774.
    • (2004) Lancet , vol.363 , pp. 768-774
    • Hacke, W.1    Donnan, G.2    Fieschi, C.3    Kaste, M.4    Von Kummer, R.5    Broderick, J.6
  • 13
    • 71849095831 scopus 로고    scopus 로고
    • Stroke treatment with alteplase given 3.0-4.5 h after onset of acute ischaemic stroke (ECASS III): Additional outcomes and subgroup analysis of a randomised controlled trial
    • Bluhmki E, Chamorro A, Dávalos A, Machnig T, Sauce C, Wahlgren N, et al. Stroke treatment with alteplase given 3.0-4.5 h after onset of acute ischaemic stroke (ECASS III): additional outcomes and subgroup analysis of a randomised controlled trial. Lancet Neurol. 2009;8:1095-1102.
    • (2009) Lancet Neurol , vol.8 , pp. 1095-1102
    • Bluhmki, E.1    Chamorro, A.2    Dávalos, A.3    Machnig, T.4    Sauce, C.5    Wahlgren, N.6
  • 14
  • 15
    • 13244271945 scopus 로고    scopus 로고
    • Comparative effects of microplasmin and tissue-type plasminogen activator (tPA) on cerebral hemorrhage in a middle cerebral artery occlusion model in mice
    • DOI 10.1111/j.1538-7836.2004.00889.x
    • Suzuki Y, Nagai N, Collen D. Comparative effects of microplasmin and tissue-type plasminogen activator (tPA) on cerebral hemorrhage in a middle cerebral artery occlusion model in mice. J Thromb Haemost. 2004;2:1617-1621. (Pubitemid 40186179)
    • (2004) Journal of Thrombosis and Haemostasis , vol.2 , Issue.9 , pp. 1617-1621
    • Suzuki, Y.1    Nagai, N.2    Collen, D.3
  • 18
    • 0034927107 scopus 로고    scopus 로고
    • Plasmin and matrix metalloproteinases in vascular remodeling
    • Lijnen H. Plasmin and matrix metalloproteinases in vascular remodeling. Thromb Haemost. 2001;86:324-333. (Pubitemid 32663963)
    • (2001) Thrombosis and Haemostasis , vol.86 , Issue.1 , pp. 324-333
    • Lijnen, H.R.1
  • 19
    • 0033666754 scopus 로고    scopus 로고
    • Metalloproteinase inhibition reduces thrombolytic (tissue plasminogen activator)-induced hemorrhage after thromboembolic stroke
    • Lapchak P, Chapman D, Zivin J. Metalloproteinase inhibition reduces thrombolytic (tissue plasminogen activator)-induced hemorrhage after thromboembolic stroke. Stroke. 2000;31:3034-3040.
    • (2000) Stroke , vol.31 , pp. 3034-3040
    • Lapchak, P.1    Chapman, D.2    Zivin, J.3
  • 20
    • 0036195260 scopus 로고    scopus 로고
    • Involvement of matrix metalloproteinase in thrombolysis-associated hemorrhagic transformation after embolic focal ischemia in rats
    • DOI 10.1161/hs0302.104542
    • Sumii T, Lo E. Involvement of matrix metalloproteinase in thrombolysis-associated hemorrhagic transformation after embolic focal ischemia in rats. Stroke. 2002;33:831-836. (Pubitemid 34204013)
    • (2002) Stroke , vol.33 , Issue.3 , pp. 831-836
    • Sumii, T.1    Lo, E.H.2
  • 21
    • 34447633015 scopus 로고    scopus 로고
    • Stromelysin-1 (MMP-3) is critical for intracranial bleeding after t-PA treatment of stroke in mice
    • DOI 10.1111/j.1538-7836.2007.02628.x
    • Suzuki Y, Nagai N, Umemura K, Collen D, Lijnen H. Stromelysin-1 (MMP-3) is critical for intracranial bleeding after t-PA treatment of stroke in mice. J Thromb Haemost. 2007;5:1732-1739. (Pubitemid 47091418)
    • (2007) Journal of Thrombosis and Haemostasis , vol.5 , Issue.8 , pp. 1732-1739
    • Suzuki, Y.1    Nagai, N.2    Umemura, K.3    Collen, D.4    Lijnen, H.R.5
  • 22
    • 0142137232 scopus 로고    scopus 로고
    • Lipoprotein receptor-mediated induction of matrix metalloproteinase by tissue plasminogen activator
    • DOI 10.1038/nm926
    • Wang X, Lee S, Arai K, Lee S, Tsuji K, Rebeck G, et al. Lipoprotein receptor-mediated induction of matrix metalloproteinase by tissue plasminogen activator. Nat Med. 2003;9:1313-1317. (Pubitemid 37279856)
    • (2003) Nature Medicine , vol.9 , Issue.10 , pp. 1313-1317
    • Wang, X.1    Lee, S.-R.2    Arai, K.3    Lee, S.-R.4    Tsuji, K.5    Rebeck, G.W.6    Lo, E.H.7
  • 24
    • 70350462242 scopus 로고    scopus 로고
    • Tissue-type plasminogen activator (t-PA) induces stromelysin-1 (MMP-3) in endothelial cells through activation of lipoprotein receptor-related protein
    • Suzuki Y, Nagai N, Yamakawa K, Kawakami J, Umemura K. Tissue-type plasminogen activator (t-PA) induces stromelysin-1 (MMP-3) in endothelial cells through activation of lipoprotein receptor-related protein. Blood. 2009;114:3352-3358.
    • (2009) Blood , vol.114 , pp. 3352-3358
    • Suzuki, Y.1    Nagai, N.2    Yamakawa, K.3    Kawakami, J.4    Umemura, K.5
  • 25
    • 36849007621 scopus 로고    scopus 로고
    • Tissue-type plasminogen activator promotes murine myofibroblast activation through LDL receptor-related protein 1-mediated integrin signaling
    • DOI 10.1172/JCI32301
    • Hu K, Wu C, Mars W, Liu Y. Tissue-type plasminogen activator promotes murine myofibroblast activation through LDL receptor-related protein 1-mediated integrin signaling. J Clin Invest. 2007;117:3821-3832. (Pubitemid 350224092)
    • (2007) Journal of Clinical Investigation , vol.117 , Issue.12 , pp. 3821-3832
    • Hu, K.1    Wu, C.2    Mars, W.M.3    Liu, Y.4
  • 26
    • 0001665337 scopus 로고
    • Surface location and high affinity for calcium of a 500-kd liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein receptor
    • Herz J, Hamann U, Rogne S, Myklebost O, Gausepohl H, Stanley K. Surface location and high affinity for calcium of a 500-kd liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein receptor. EMBO J. 1988;7:4119-4127.
    • (1988) EMBO J , vol.7 , pp. 4119-4127
    • Herz, J.1    Hamann, U.2    Rogne, S.3    Myklebost, O.4    Gausepohl, H.5    Stanley, K.6
  • 27
    • 0026756089 scopus 로고
    • Low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor is an hepatic receptor for tissue-type plasminogen activator
    • Bu G, Williams S, Strickland D, Schwartz A. Low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor is an hepatic receptor for tissue-type plasminogen activator. Proc Natl Acad Sci U S A. 1992;89:7427-7431.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 7427-7431
    • Bu, G.1    Williams, S.2    Strickland, D.3    Schwartz, A.4
  • 28
    • 50349092250 scopus 로고    scopus 로고
    • LDL receptor-related protein 1: Unique tissue-specific functions revealed by selective gene knockout studies
    • Lillis A, Van Duyn L, Murphy-Ullrich J, Strickland D. LDL receptor-related protein 1: unique tissue-specific functions revealed by selective gene knockout studies. Physiol Rev. 2008;88:887-918.
    • (2008) Physiol Rev , vol.88 , pp. 887-918
    • Lillis, A.1    Van Duyn, L.2    Murphy-Ullrich, J.3    Strickland, D.4
  • 30
    • 34548076607 scopus 로고    scopus 로고
    • Interferon-gamma regulation of TNFalpha-induced matrix metalloproteinase 3 expression and migration of human glioma T98G cells
    • DOI 10.1002/ijc.22729
    • Cheng S, Xing B, Li J, Cheung B, Lau A. Interferon-gamma regulation of TNFalpha-induced matrix metalloproteinase 3 expression and migration of human glioma T98G cells. Int J Cancer. 2007;121:1190-1196. (Pubitemid 47293784)
    • (2007) International Journal of Cancer , vol.121 , Issue.6 , pp. 1190-1196
    • Cheng, S.M.1    Xing, B.2    Li, J.C.B.3    Cheung, B.K.W.4    Lau, A.S.Y.5
  • 31
    • 0033545863 scopus 로고    scopus 로고
    • Defining therapeutic targets by using adenovirus: Blocking NF-kappaB inhibits both inflammatory and destructive mechanisms in rheumatoid synovium but spares anti-inflammatory mediators
    • DOI 10.1073/pnas.96.10.5668
    • Bondeson J, Foxwell B, Brennan F, Feldmann M. Defining therapeutic targets by using adenovirus: blocking NF-kappaB inhibits both inflammatory and destructive mechanisms in rheumatoid synovium but spares anti-inflammatory mediators. Proc Natl Acad Sci U S A. 1999;96:5668-5673. (Pubitemid 29234676)
    • (1999) Proceedings of the National Academy of Sciences of the United States of America , vol.96 , Issue.10 , pp. 5668-5673
    • Bondeson, J.1    Foxwell, B.2    Brennan, F.3    Feldmann, M.4
  • 32
    • 0345643514 scopus 로고    scopus 로고
    • Regulation of matrix metalloproteinase expression in tumor invasion
    • Westermarck J, Kahari VM. Regulation of matrix metalloproteinase expression in tumor invasion. FASEB J. 1999;13:781-792. (Pubitemid 29220691)
    • (1999) FASEB Journal , vol.13 , Issue.8 , pp. 781-792
    • Westermarck, J.1    Kahari, V.-M.2
  • 33
    • 35348892539 scopus 로고    scopus 로고
    • Tissue-type plasminogen activator and the low-density lipoprotein receptor-related protein mediate cerebral ischemia-induced nuclear factor-kappaB pathway activation
    • DOI 10.2353/ajpath.2007.070472
    • Zhang X, Polavarapu R, She H, Mao Z, Yepes M. Tissue-type plasminogen activator and the low-density lipoprotein receptorrelated protein mediate cerebral ischemia-induced nuclear factorkappaB pathway activation. Am J Pathol. 2007;171:1281-1290. (Pubitemid 47582901)
    • (2007) American Journal of Pathology , vol.171 , Issue.4 , pp. 1281-1290
    • Zhang, X.1    Polavarapu, R.2    She, H.3    Mao, Z.4    Yepes, M.5
  • 34
    • 0037192458 scopus 로고    scopus 로고
    • Matrix metalloproteinase inhibitors and cancer: Trials and tribulations
    • DOI 10.1126/science.1067100
    • Coussens L, Fingleton B, Matrisian L. Matrix metalloproteinase inhibitors and cancer: trials and tribulations. Science. 2002;295:2387-2392. (Pubitemid 34270240)
    • (2002) Science , vol.295 , Issue.5564 , pp. 2387-2392
    • Coussens, L.M.1    Fingleton, B.2    Matrisian, L.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.