Controversies in the treatment of the acutely wheezing infant

American Journal of Respiratory and Critical Care Medicine

Volumn 183, Issue 10, 2011, Pages 1284-1285

  Guilbert, Theresa W ^a   Bacharier, Leonard B ^b  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b ST LOUIS CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; BRONCHODILATING AGENT; CORTICOSTEROID; DEXAMETHASONE; MONTELUKAST; SODIUM CHLORIDE;

ACUTE DISEASE; ASTHMA; CLINICAL TRIAL (TOPIC); DISEASE COURSE; DISEASE SEVERITY; DRUG EFFICACY; DRUG TREATMENT FAILURE; EDITORIAL; HOSPITAL ADMISSION; HOSPITALIZATION; HUMAN; IMMUNITY; INFANT DISEASE; LOWER RESPIRATORY TRACT INFECTION; PATHOGENESIS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); RECURRENT DISEASE; RESPIRATORY TRACT INFECTION; RESPIRATORY TRACT INFLAMMATION; RESPIRATORY TRACT INJURY; RHINOVIRUS; RHINOVIRUS INFECTION; RISK FACTOR; TREATMENT DURATION; UNSPECIFIED SIDE EFFECT; VIRAL BRONCHIOLITIS; WHEEZING;

ACUTE DISEASE; ADRENAL CORTEX HORMONES; BRONCHIOLITIS; HUMANS; INFANT; RESPIRATORY SOUNDS;

EID: 79956195539     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201008-1331ED     Document Type: Editorial

References (18)

1. Akinbami L. The state of childhood asthma, United States, 1980-2005. Adv Data 2006;381:1-24.
2. Jackson DJ, Gangnon RE, Evans MD, Roberg KA, Anderson EL, Pappas TE, Printz MC, Lee WM, Shult PA, Reisdorf E, et al. Wheezing rhinovirus illnesses in early life predict asthma development in high risk children. Am J Respir Crit Care Med 2008;178:667-672.
3. Stein RT, Sherrill D, Morgan WJ, Holberg CJ, Halonen M, Taussig LM, Wright AL, Martinez FD. Respiratory syncytial virus in early life and risk of wheeze and allergy by age 13 years. Lancet 1999;354: 541-545. (Pubitemid 29381367)
4. Martinez FD, Wright AL, Taussig LM, Holberg CJ, Halonen M, Morgan WJ. Asthma and wheezing in the first six years of life: the group health medical associates. N Engl J Med 1995;332:133-138.
5. Kusel MM, de Klerk NH, Kebadze T, Vohma V, Holt PG, Johnston SL, Sly PD. Early-life respiratory viral infections, atopic sensitization, and risk of subsequent development of persistent asthma. J Allergy Clin Immunol 2007;119:1105-1110. (Pubitemid 46654175)
6. Sly PD, Kusel M, Holt PG. Do early-life viral infections cause asthma? J Allergy Clin Immunol 2010;125:1202-1205.
7. Holt PG, Upham JW, Sly PD. Contemporaneous maturation of immunologic and respiratory functions during early childhood: implications for development of asthma prevention strategies. J Allergy Clin Immunol 2005;116:16-24, quiz 25.
8. Wainwright C. Acute viral bronchiolitis in children: a very common condition with few therapeutic options. Paediatr Respir Rev 2010;11:39-45, quiz 45.
9. Lehtinen P, Ruohola A, Vanto T, Vuorinen T, Ruuskanen O, Jartti T. Prednisolone reduces recurrent wheezing after a first wheezing episode associated with rhinovirus infection or eczema. J Allergy Clin Immunol 2007;119:570-575.
10. Plint AC, Johnson DW, Patel H, Wiebe N, Correll R, Brant R, Mitton C, Gouin S, Bhatt M, Joubert G, et al. Epinephrine and dexamethasone in children with bronchiolitis. N Engl J Med 2009;360:2079-2089.
11. Zhang L, Mendoza-Sassi RA, Wainwright C, Klassen TP. Nebulized hypertonic saline solution for acute bronchiolitis in infants. Cochrane Database Syst Rev 2008;CD006458.
12. Ralston S, Hill V, Martinez M. Nebulized hypertonic saline without adjunctive bronchodilators for children with bronchiolitis. Pediatrics 2010;126:e520-e525.
13. Csonka P, Kaila M, Laippala P, Iso-Mustajarvi M, Vesikari T, Ashorn P. Oral prednisolone in the acute management of children age 6 to 35 months with viral respiratory infection-induced lower airway disease: a randomized, placebo-controlled trial. J Pediatr 2003;143:725-730. (Pubitemid 37510639)
14. Oommen A, Lambert PC, Grigg J. Efficacy of a short course of parent-initiated oral prednisolone for viral wheeze in children aged 1-5 years: randomised controlled trial. Lancet 2003;362:1433-1438. (Pubitemid 37352878)
15. Panickar J, Lakhanpaul M, Lambert PC, Kenia P, Stephenson T, Smyth A, Grigg J. Oral prednisolone for preschool children with acute virus-induced wheezing. N Engl J Med 2009;360:329-338.
16. Castro-Rodriguez JA, Holberg CJ, Wright AL, Martinez FD. A clinical index to define risk of asthma in young children with recurrent wheezing. Am J Respir Crit Care Med 2000;162:1403-1406.
17. Bush A. Practice imperfect-treatment for wheezing in preschoolers. N Engl J Med 2009;360:409-410.
18. Grigg J. Role of systemic steroids in acute preschool wheeze. Arch Dis Child 2010;95:491-492.