메뉴 건너뛰기




Volumn 118, Issue 4, 2011, Pages 531-538

Down regulation of trophic factors in neonatal rat spinal cord after administration of cerebrospinal fluid from sporadic amyotrophic lateral sclerosis patients

Author keywords

ALS CSF; BDNF; FGF2; IGF1; Rat spinal cord; Sporadic ALS

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; FIBROBLAST GROWTH FACTOR 2; MESSENGER RNA; SOMATOMEDIN C; VOLTAGE GATED SODIUM CHANNEL;

EID: 79956194152     PISSN: 03009564     EISSN: 14351463     Source Type: Journal    
DOI: 10.1007/s00702-010-0520-6     Document Type: Article
Times cited : (29)

References (43)
  • 1
    • 0344076149 scopus 로고    scopus 로고
    • A controlled trial of recombinant methionyl human BDNF in ALS: The BDNF Study Group (Phase III)
    • No authors listed
    • (No authors listed) (1999) A controlled trial of recombinant methionyl human BDNF in ALS: The BDNF Study Group (Phase III). Neurology 52:1427-1433
    • (1999) Neurology , vol.52 , pp. 1427-1433
  • 2
    • 0028181152 scopus 로고
    • Insulin-like growth factor-1 receptors in human spinal cord: Changes in amyotrophic lateral sclerosis
    • Adem A, Ekblom J (1994) Insulin-like growth factor-1 receptors in human spinal cord: changes in amyotrophic lateral sclerosis. J Neural Transm Gen Sect 97:73-84
    • (1994) J Neural Transm Gen Sect , vol.97 , pp. 73-84
    • Adem, A.1    Ekblom, J.2
  • 3
    • 77952546947 scopus 로고    scopus 로고
    • Expression of GDNF receptors GFRα1 and RET is preserved in substantia nigra pars compacta of aging Asian Indians
    • Alladi PA, Mahadevan A, Shankar SK, Raju TR, Muthane U (2010) Expression of GDNF receptors GFRα1 and RET is preserved in substantia nigra pars compacta of aging Asian Indians. J Chem Neuroanat 40(1):43-52
    • (2010) J Chem Neuroanat , vol.40 , Issue.1 , pp. 43-52
    • Alladi, P.A.1    Mahadevan, A.2    Shankar, S.K.3    Raju, T.R.4    Muthane, U.5
  • 4
    • 0028951044 scopus 로고
    • Regional changes of ciliary neurotrophic factor and nerve growth factor levels in post mortem spinal cord and cerebral cortex from patients with motor disease
    • Anand P, Parrett A (1995) Regional changes of ciliary neurotrophic factor and nerve growth factor levels in post mortem spinal cord and cerebral cortex from patients with motor disease. Nat Med 1(2):168-172
    • (1995) Nat Med , vol.1 , Issue.2 , pp. 168-172
    • Anand, P.1    Parrett, A.2
  • 5
    • 0032869840 scopus 로고    scopus 로고
    • Neurotrophic factors in the therapy of diabetic neuropathy
    • Apfel SC (1999) Neurotrophic factors in the therapy of diabetic neuropathy. Am J Med 107:34S-42S
    • (1999) Am J Med , vol.107
    • Apfel, S.C.1
  • 6
    • 0024677597 scopus 로고
    • Trophic factors and neuronal survival
    • Barde YA (1989) Trophic factors and neuronal survival. Neuron 6:1525-1534
    • (1989) Neuron , vol.6 , pp. 1525-1534
    • Barde, Y.A.1
  • 7
    • 0028262978 scopus 로고
    • Distinct neurotrophic responses of axotomized motor neurons to BDNF and CNTF in adult rats
    • Chiu AY, Chen EW, Lorea S (1994) Distinct neurotrophic responses of axotomized motor neurons to BDNF and CNTF in adult rats. Neuroreport 6:693-696 (Pubitemid 24110357)
    • (1994) NeuroReport , vol.5 , Issue.6 , pp. 693-696
    • Chiu, A.Y.1    Chen, E.W.2    Loera, S.3
  • 8
    • 0029084287 scopus 로고
    • Acidic fibroblast growth factor prevents post-axotomy neuronal death of the newborn rat facial nerve
    • Cuevas P, Carceller F, Giménez-Gallego G (1995) Acidic fibroblast growth factor prevents post-axotomy neuronal death of the newborn rat facial nerve. Neurosci Lett 197:183-186
    • (1995) Neurosci Lett , vol.197 , pp. 183-186
    • Cuevas, P.1    Carceller, F.2    Giménez-Gallego, G.3
  • 9
    • 0032806529 scopus 로고    scopus 로고
    • Activation of phosphatidylinositol 3-kinase, but not extracellular- regulated kinases, is necessary to mediate brain-derived neurotrophic factor- induced motoneuron survival
    • DOI 10.1046/j.1471-4159.1999.0730521.x
    • Dolcet X, Egea J, Soler RM, Martin Zanca D, Comella JX (1999) Activation of phosphatidylinositol 3-kinase, but not extracellular-regulated kinases is necessary to mediate brain-derived neurotrophic factor-induced motoneuron survival. J Neurochem 73:521-531 (Pubitemid 29339824)
    • (1999) Journal of Neurochemistry , vol.73 , Issue.2 , pp. 521-531
    • Dolcet, X.1    Egea, J.2    Soler, R.M.3    Martin-Zanca, D.4    Comella, J.X.5
  • 10
    • 0343765729 scopus 로고    scopus 로고
    • Re-discovering an old friend, IGF-I: Potential use in the treatment of neurodegenerative diseases
    • Doré S, Kar S, Quirion R (1997) Re-discovering an old friend, IGF-I: potential use in the treatment of neurodegenerative diseases. Trends Neurosci 20:326-331
    • (1997) Trends Neurosci , vol.20 , pp. 326-331
    • Doré, S.1    Kar, S.2    Quirion, R.3
  • 11
    • 0021944296 scopus 로고
    • Motoneurone survival is induced by immature astrocytes from developing avian spinal cord
    • DOI 10.1016/0165-3806(85)90135-X
    • Eagleson KL, Raju TR, Bennet MR (1985) Motoneurone survival is induced by immature astrocytes from developing avian spinal cord. Brain Res 349(1-2):95-104 (Pubitemid 15133100)
    • (1985) Developmental Brain Research , vol.17 , Issue.1-2 , pp. 95-104
    • Eagleson, K.L.1    Raju, T.R.2    Bennett, M.R.3
  • 12
    • 5644229846 scopus 로고    scopus 로고
    • Neurotrophic factors and amyotrophic lateral sclerosis
    • Ekestern E (2004) Neurotrophic factors and amyotrophic lateral sclerosis. Neurodegener Dis 1:88-100
    • (2004) Neurodegener Dis , vol.1 , pp. 88-100
    • Ekestern, E.1
  • 13
    • 0028217132 scopus 로고
    • Requirement for BDNF in activity-dependent survival of cortical neurons
    • Ghosh A, Carnahan J, Greenberg ME (1994) Requirement for BDNF in activity-dependent survival of cortical neurons. Science 263:1618-1623 (Pubitemid 24128367)
    • (1994) Science , vol.263 , Issue.5153 , pp. 1618-1623
    • Ghosh, A.1    Carnahan, J.2    Greenberg, M.E.3
  • 14
    • 0025936214 scopus 로고
    • Effects of basic fibroblast growth factor on survival and choline acetyltransferase development of spinal cord neurons
    • Grothe C, Wewetzer K, Lagrange A, Unsicker K (1991) Effects of basic fibroblast growth factor on survival and choline acetyltransferase development of spinal cord neurons. Brain Res Dev Brain Res 62:257-261
    • (1991) Brain Res Dev Brain Res , vol.62 , pp. 257-261
    • Grothe, C.1    Wewetzer, K.2    Lagrange, A.3    Unsicker, K.4
  • 15
    • 59249109196 scopus 로고    scopus 로고
    • Exposure to cerebrospinal fluid of sporadic amyotrophic lateral sclerosis patients alters Nav1.6 and Kv1.6 channel expression in rat spinal motor neurons
    • Gunasekaran R, Narayani RS, Vijayalakshmi K, Alladi PA, Shobha K, Nalini A, Sathyaprabha TN, Raju TR (2009) Exposure to cerebrospinal fluid of sporadic amyotrophic lateral sclerosis patients alters Nav1.6 and Kv1.6 channel expression in rat spinal motor neurons. Brain Res 1255:170-179
    • (2009) Brain Res , vol.1255 , pp. 170-179
    • Gunasekaran, R.1    Narayani, R.S.2    Vijayalakshmi, K.3    Alladi, P.A.4    Shobha, K.5    Nalini, A.6    Sathyaprabha, T.N.7    Raju, T.R.8
  • 16
    • 0034175688 scopus 로고    scopus 로고
    • Role of glycogen synthase kinase-3beta in neuronal apoptosis induced by trophic withdrawal
    • Hetman M, Cavanaugh JE, Kimelman D, Xia Z (2000) Role of glycogen synthase kinase-3 beta in neuronal apoptosis induced by trophic withdrawal. J Neurosci 20:2567-2574 (Pubitemid 30220344)
    • (2000) Journal of Neuroscience , vol.20 , Issue.7 , pp. 2567-2574
    • Hetman, M.1    Cavanaugh, J.E.2    Kimelman, D.3    Zhengui, X.4
  • 17
    • 0027414519 scopus 로고
    • Evidence that fibroblast growth factor 5 is a major muscle-derived survival factor for cultured spinal motoneurons
    • DOI 10.1016/0896-6273(93)90327-N
    • Hughes RA, Sendtner M, Goldfarb M, Lindholm D, Thoenen H (1993) Evidence that fibroblast growth factor 5 is a major muscle-derived survival factor for cultured spinal motoneurons. Neuron 10:369-377 (Pubitemid 23111730)
    • (1993) Neuron , vol.10 , Issue.3 , pp. 369-377
    • Hughes, R.A.1    Sendtner, M.2    Goldfarb, M.3    Lindholm, D.4    Thoenen, H.5
  • 18
    • 0028868845 scopus 로고
    • Neuroprotective effect of basic fibroblast growth factor on wobbler mouse motor neuron disease
    • Ikeda K, Iwasaki Y, Tagaya N, Shiojima T, Kobayashi T, Kinoshita M (1995) Neuroprotective effect of basic fibroblast growth factor on wobbler mouse motor neuron disease. Neurol Res 17:445-448
    • (1995) Neurol Res , vol.17 , pp. 445-448
    • Ikeda, K.1    Iwasaki, Y.2    Tagaya, N.3    Shiojima, T.4    Kobayashi, T.5    Kinoshita, M.6
  • 19
    • 0037135166 scopus 로고    scopus 로고
    • Methionine-free brain-derived neurotrophic factor in wobbler mouse motor neuron disease: Dose-related effects and comparison with the methionyl form
    • DOI 10.1016/S0006-8993(02)02881-0, PII S0006899302028810
    • Ishiyama T, Ogo H, Wongc V, Klinkosza B, Noguchib H, Nakayamab C, Mitsumoto H (2002) Methionine-free brain-derived neurotrophic factor in wobbler mouse motor neuron disease: dose-related effects and comparison with the methionyl form. Brain Res 944:195-199 (Pubitemid 34775022)
    • (2002) Brain Research , vol.944 , Issue.1-2 , pp. 195-199
    • Ishiyama, T.1    Ogo, H.2    Wong, V.3    Klinkosz, B.4    Noguchi, H.5    Nakayama, C.6    Mitsumoto, H.7
  • 20
    • 0035807925 scopus 로고    scopus 로고
    • Acidic fibroblast growth factor (FGF-I) in the anterior horn cells of ALS and control cases
    • Kage M, Yang Q, Yang Q, Sato H, Matsumoto S, Kaji R, Akiguchi I, Kimura H, Tooyama I (2001) Acidic fibroblast growth factor (FGF-1) in the anterior horn cells of ALS and control cases. Neuroreport 12:3799-3803 (Pubitemid 33105175)
    • (2001) NeuroReport , vol.12 , Issue.17 , pp. 3799-3803
    • Kage, M.1    Yang, Q.2    Sato, H.3    Matsumoto, S.4    Kaji, R.5    Akiguchi, I.6    Kimura, H.7    Tooyama, I.8
  • 21
    • 0042528664 scopus 로고    scopus 로고
    • Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model
    • DOI 10.1126/science.1086137
    • Kaspar B, Llado KJ, Sherkat N, Rothstein JD, Gage FH (2003) Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model. Science 301:839-842 (Pubitemid 36962626)
    • (2003) Science , vol.301 , Issue.5634 , pp. 839-842
    • Kaspar, B.K.1    Llado, J.2    Sherkat, N.3    Rothstein, J.D.4    Gage, F.H.5
  • 22
    • 0031128211 scopus 로고    scopus 로고
    • BDNF prevents and reverses adult rat motor neuron degeneration and induces axonal outgrowth
    • DOI 10.1006/exnr.1996.6367
    • Kishino A, Ishige Y, Tatsuno T, Nakayama C, Noguchi H (1997) BDNF prevents and reverses adult rat motor neuron degeneration and induces axonal outgrowth. Exp Neurol 144:273-286 (Pubitemid 27224556)
    • (1997) Experimental Neurology , vol.144 , Issue.2 , pp. 273-286
    • Kishino, A.1    Ishige, Y.2    Tatsuno, T.3    Nakayama, C.4    Noguchi, H.5
  • 24
    • 0035710746 scopus 로고    scopus 로고
    • -DeltaDeltaCT method
    • DOI 10.1006/meth.2001.1262
    • Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25:402-408 (Pubitemid 34164012)
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 26
    • 0032586402 scopus 로고    scopus 로고
    • Neurotrophic factors and neuromuscular disease: II. GDNF, other neurotrophic factors, and future directions
    • Mitsumoto H, Tsuzaka K (1999) Neurotrophic factors and neuromuscular disease: II. GDNF, other neurotrophic factors, and future directions. Muscle Nerve 22:1000-1021
    • (1999) Muscle Nerve , vol.22 , pp. 1000-1021
    • Mitsumoto, H.1    Tsuzaka, K.2
  • 27
    • 0032507658 scopus 로고    scopus 로고
    • Neutrophin switching in spinal motoneurons of amyotrophic lateral sclerosis
    • Nishio T, Sunohara N, Furukawa S (1998) Neutrophin switching in spinal motoneurons of amyotrophic lateral sclerosis. Neuroreport 9:1661-1665 (Pubitemid 28264305)
    • (1998) NeuroReport , vol.9 , Issue.7 , pp. 1661-1665
    • Nishio, T.1    Sunohara, N.2    Furukawa, S.3
  • 28
    • 0027094145 scopus 로고
    • Brain-derived neurotrophic factor rescues developing avian motoneurons from cell death
    • DOI 10.1038/360755a0
    • Oppenheim RW, Yin QW, Prevette D, Yan Q (1992) Brain-derived neurotrophic factor rescues developing avian motoneurons from cell death. Nature 360:755-757 (Pubitemid 23012275)
    • (1992) Nature , vol.360 , Issue.6406 , pp. 755-757
    • Oppenheim, R.W.1    Qin-Wei, Y.2    Prevette, D.3    Yan, Q.4
  • 29
    • 0029610566 scopus 로고
    • Neurofilament phosphorylation is increased in ventral horn neurons of neonatal rat spinal cord exposed to cerebrospinal fluid from patients with amyotrophic lateral sclerosis
    • DOI 10.1006/neur.1995.0048
    • Rao MS, Devi MG, Nalini A, Shahani N, Raju TR (1995) Neurofilament phosphorylation is increased in ventral horn neurons of neonatal rat spinal cord exposed to cerebrospinal fluid from patients with amyotrophic lateral sclerosis. Neurodegeneration 4:397-401 (Pubitemid 26016585)
    • (1995) Neurodegeneration , vol.4 , Issue.4 , pp. 397-401
    • Rao, M.S.1    Devi, M.G.2    Nalini, A.3    Shahani, N.4    Raju, T.R.5
  • 30
    • 0029847118 scopus 로고    scopus 로고
    • Excitotoxicity hypothesis
    • discussion S26
    • Rothstein JD (1996) Excitotoxicity hypothesis. Neurology 47:S19-S25 (discussion S26)
    • (1996) Neurology , vol.47
    • Rothstein, J.D.1
  • 31
    • 0034326790 scopus 로고    scopus 로고
    • Six important themes in amyotrophic lateral sclerosis (ALS) research
    • Rowland LP (2000) Six important themes in amyotrophic lateral sclerosis (ALS) research. J Neurol Sci 180:2-6
    • (2000) J Neurol Sci , vol.180 , pp. 2-6
    • Rowland, L.P.1
  • 32
    • 0026787533 scopus 로고
    • Novel roles for neurotrophins are suggested by BDNF and NT-3 mRNA expression in developing neurons
    • Schecterson LC, Bothwell M (1992) Novel roles for neurotrophins are suggested by BDNF and NT-3 mRNA expression in developing neurons. Neuron 9:449-463
    • (1992) Neuron , vol.9 , pp. 449-463
    • Schecterson, L.C.1    Bothwell, M.2
  • 33
    • 77953078946 scopus 로고    scopus 로고
    • Counteracting muscle wasting in aging and neuromuscular diseases: The critical role of IGF-1
    • Albany NY
    • Scicchitano BM, Rizzuto E, Musarò A (2009) Counteracting muscle wasting in aging and neuromuscular diseases: the critical role of IGF-1. Aging (Albany NY) 1:451-457
    • (2009) Aging , vol.1 , pp. 451-457
    • Scicchitano, B.M.1    Rizzuto, E.2    Musarò, A.3
  • 34
    • 0029925683 scopus 로고    scopus 로고
    • Intracellular signaling pathways activated by neurotrophic factors
    • Segal RA, Greenberg ME (1996) Intracellular signaling pathways activated by neurotrophic factors. Annu Rev Neurosci 19:463-489 (Pubitemid 26080836)
    • (1996) Annual Review of Neuroscience , vol.19 , pp. 463-489
    • Segal, R.A.1    Greenberg, M.E.2
  • 35
    • 0027070473 scopus 로고
    • Brain-derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section
    • DOI 10.1038/360757a0
    • Sendtner M, Holtmann B (1992) Brain-derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section. Nature 360:757-759 (Pubitemid 23012276)
    • (1992) Nature , vol.360 , Issue.6406 , pp. 757-759
    • Sendtner, M.1    Holtmann, B.2    Kolbeck, R.3    Thoenen, H.4    Barde, Y.-A.5
  • 36
    • 0031913675 scopus 로고    scopus 로고
    • Reactive astrogliosis in neonatal rat spinal cord after exposure to cerebrospinal fluid from patients with amyotrophic lateral sclerosis
    • DOI 10.1006/exnr.1997.6651
    • Shahani N, Nalini A, Gourie-Devi M, Raju TR (1998) Reactive astrogliosis in neonatal rat spinal cord after exposure to cerebrospinal fluid from patients with amyotrophic lateral sclerosis. Exp Neurol 149:295-298 (Pubitemid 28091039)
    • (1998) Experimental Neurology , vol.149 , Issue.1 , pp. 295-298
    • Shahani, N.1    Nalini, A.2    Gourie-Devi, M.3    Raju, T.R.4
  • 37
    • 33847330077 scopus 로고    scopus 로고
    • Altered in-vitro and in-vivo expression of glial glutamate transporter-1 following exposure to cerebrospinal fluid of amyotrophic lateral sclerosis patients
    • DOI 10.1016/j.jns.2006.12.004, PII S0022510X06005624
    • Shobha K, Vijayalakshmi K, Alladi PA, Nalini A, Sathyaprabha TN, Raju TR (2007) Altered in vitro and in vivo expression of glial glutamate transporter-1 following exposure to cerebrospinal fluid of amyotrophic lateral sclerosis patients. J Neurol Sci 254:9-16 (Pubitemid 46330401)
    • (2007) Journal of the Neurological Sciences , vol.254 , Issue.1-2 , pp. 9-16
    • Shobha, K.1    Vijayalakshmi, K.2    Alladi, P.A.3    Nalini, A.4    Sathyaprabha, T.N.5    Raju, T.R.6
  • 38
    • 77950629099 scopus 로고    scopus 로고
    • Exposure to CSF from sporadic amyotrophic lateral sclerosis patients induces morphological transformation of astroglia and enhances GFAP and S100beta expression
    • Shobha K, Alladi PA, Nalini A, Raju TR, Sathyaprabha TN (2010) Exposure to CSF from sporadic amyotrophic lateral sclerosis patients induces morphological transformation of astroglia and enhances GFAP and S100beta expression. Neurosci Lett 473:56-61
    • (2010) Neurosci Lett , vol.473 , pp. 56-61
    • Shobha, K.1    Alladi, P.A.2    Nalini, A.3    Raju, T.R.4    Sathyaprabha, T.N.5
  • 39
    • 0038693216 scopus 로고    scopus 로고
    • The basic aspects of therapeutics in amyotrophic lateral sclerosis
    • Strong MJ (2003) The basic aspects of therapeutics in amyotrophic lateral sclerosis. Pharmacol Ther 98:379-414
    • (2003) Pharmacol Ther , vol.98 , pp. 379-414
    • Strong, M.J.1
  • 40
    • 62249189611 scopus 로고    scopus 로고
    • Cerebrospinal fluid from sporadic amyotrophic lateral sclerosis patients induces degeneration of a cultured motor neuron cell line
    • Vijayalakshmi K, Alladi PA, Sathyaprabha TN, Subramaniam JR, Nalini A, Raju TR (2009) Cerebrospinal fluid from sporadic amyotrophic lateral sclerosis patients induces degeneration of a cultured motor neuron cell line. Brain Res 1263:122-133
    • (2009) Brain Res , vol.1263 , pp. 122-133
    • Vijayalakshmi, K.1    Alladi, P.A.2    Sathyaprabha, T.N.3    Subramaniam, J.R.4    Nalini, A.5    Raju, T.R.6
  • 41
    • 2942695980 scopus 로고    scopus 로고
    • IGF-I prevents glutamate-induced motor neuron programmed cell death
    • DOI 10.1016/j.nbd.2004.03.001, PII S0969996104000658
    • Vincent AM, Mobley BC (2004) IGF-I prevents glutamate-induced motor neuron programmed cell death. Neurobiol Dis 16:407-416 (Pubitemid 38765100)
    • (2004) Neurobiology of Disease , vol.16 , Issue.2 , pp. 407-416
    • Vincent, A.M.1    Mobley, B.C.2    Hiller, A.3    Feldman, E.L.4
  • 42
    • 0027316366 scopus 로고
    • The neurotrophins BDNF, NT-3 and NT-4/5, but not NGF, up-regulate the cholinergic phenotype of developing motor neurons
    • Wong V, Arriaga R, Ip NY, Lindsay RM (1993) The neurotrophins BDNF, NT-3 and NT-4/5, but not NGF, up-regulate the cholinergic phenotype of developing motor neurons. Eur J Neurosci 5:466-474 (Pubitemid 23168293)
    • (1993) European Journal of Neuroscience , vol.5 , Issue.5 , pp. 466-474
    • Wong, V.1    Arriaga, R.2    Ip, N.Y.3    Lindsay, R.M.4
  • 43
    • 0027067035 scopus 로고
    • Brain-derived neurotrophic factor rescues spinal motor neurons from axotomy-induced cell death
    • DOI 10.1038/360753a0
    • Yan Q, Elliott J (1992) Brain-derived neurotrophic factor rescues spinal motor neurons from axotomy-induced cell death. Nature 360:753-755 (Pubitemid 23012274)
    • (1992) Nature , vol.360 , Issue.6406 , pp. 753-755
    • Yan, Q.1    Elliott, J.2    Snider, W.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.