Synthesis of nicotinamide derivatives having a hydroxy-substituted benzene ring and the influence of their structures on the apoptosis-inducing activity against leukemia cells

Drug Development Research

Volumn 72, Issue 3, 2011, Pages 289-297

  Yamaguchi, Tomoko ^a   Matsumura, Yuriko ^a   Ishii, Takuya ^b   Tokuoka, Yoshikazu ^b   Kurita, Keisuke ^a  

^a SEIKEI UNIVERSITY   (Japan)

^b TOIN UNIVERSITY OF YOKOHAMA   (Japan)

Author keywords

anticancer agent; apoptosis inducing activity; leukemia cells; nicotinamide derivatives

Indexed keywords

ANTINEOPLASTIC AGENT; BENZENE; EPIGALLOCATECHIN GALLATE; N NICOTINOYL O (2 HYDROXY 4 METHXYBENZOYL) TYROSINE METHYL ESTER; N NICOTINOYL O (2 HYDROXY 5 METHOXYBENZOYL) TYROSINE METHYL ESTER; N NICOTINOYL O (2 HYDROXYBENZOYL) TYROSINE METHYL ESTER; N NICOTINOYL O (2 METHOXYBENZOYL) TYROSINE METHYL ESTER; N NICOTINOYL O (2,3 DIHYDROXYBENZOYL) TYROSINE METHYL ESTER; N NICOTINOYL O (2,3 DIMETHOXYBENZOYL) TYROSINE METHYL ESTER; N NICOTINOYL O (2,4 DIMETHOXYBENZOYL) TYROSINE METHYL ESTER; N NICOTINOYL O (2,5 DIHYDROXYBENZOYL) TYROSINE METHYL ESTER; N NICOTINOYL O (2,5 DIMETHOXYBENZOYL) TYROSINE METHYL ESTER; N NICOTINOYL O (3 HYDROXYBENZOYL) TYROSINE METHYL ESTER; N NICOTINOYL O (3 METHOXYBENZOYL) TYROSINE METHYL ESTER; N NICOTINOYL O (4 ACETOXYBENZOYL) TYROSINE METHYL ESTER; N NICOTINOYL O (4 HYDROXYBENZOYL) TYROSINE METHYL ESTER; N NICOTINOYL O (4 METHOXYBENZOYL) TYROSINE METHYL ESTER; N NICOTINOYLDOPAMINE; N NICOTINOYLNOREPINEPHRINE; NICOTINAMIDE DERIVATIVE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL STRAIN U937; DRUG STRUCTURE; DRUG SYNTHESIS; IC 50;

EID: 79956146811     PISSN: 02724391     EISSN: 10982299     Source Type: Journal    
DOI: 10.1002/ddr.20426     Document Type: Article

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