Dopamine inhibits proliferation, induces differentiation and apoptosis of K562 leukaemia cells

Chinese Medical Journal

Volumn 120, Issue 11, 2007, Pages 970-974

  He, Qun ^a   Yuan, Lin Bo ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Apoptosis; Differentiation; Dopamine; Proliferation

Indexed keywords

BENZIDINE; CD71 ANTIGEN; DOPAMINE;

ANTIGEN EXPRESSION; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL ASSAY; CELL COUNT; CELL CYCLE G1 PHASE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL STRAIN K 562; CELL STRUCTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; LEUKEMIA CELL; LIQUID CULTURE;

EID: 34250204535     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: 10.1097/00029330-200706010-00006     Document Type: Article

References (21)

1. Smythies J. Section II. The dopamine system. Int Rev Neurobiol 2005; 64: 123-172.
2. Seutin V. Dopaminergic neurones: much more than dopamine? Br J Pharmacol 2005; 146: 167-169.
3. Chinta SJ, Andersen JK. Dopaminergic neurons. Int J Biochem Cell Biol 2005; 37: 942-946.
4. Thompson MD, Burnham WM, Cole DE. The G protein-coupled receptors: pharmacogenetics and disease. Crit Rev Clin Lab Sci 2005; 42: 311-392.
5. Metaye T, Gibelin H, Perdrisot R, Kraimps JL. Pathophysiological roles of G-protein-coupled receptor kinases. Cell Signal 2005; 17: 917-928.
6. Soudijn W, van Wijngaarden I, Ijzerman AP. Structure-activity relationships of inverse agonists for G-protein-coupled receptors. Med Res Rev 2005; 25: 398-426.
7. Ozono R. Dopamine. Nippon Rinsho 2005; 63 Suppl 8: s388-s390.
8. Waddington JL, O'Tuathaigh C, O'Sullivan G, Tomiyama K, Koshikawa N, Croke DT. Phenotypic studies on dopamine receptor subtype and associated signal transduction mutants: insights and challenges from 10 years at the psychopharmacology-molecular biology interface. Psychopharmacology 2005; 181: 611-638.
9. Bannon MJ. The dopamine transporter: role in neurotoxicity and human disease. Toxicol Appl Pharmacol 2005; 204: 355-360.
10. Klein E, Ben-Bassat H, Neumann H, Ralph P, Zeuthen J, Polliack A, et al. Properties of the K562 cell line, derived from a patient with chronic myeloid leukemia. Int J Cancer 1976; 18: 421-431.
11. Carmichael J, DeGraff WG, Gazdar AF, Minna JD, Mitchell JB. Evaluation of a tetrazolium-based semiantomated colorimetric assay: assessment of chemosensitivity testing. Cancer Res 1987; 47: 936-942.
12. Wanda PE, Lee LT, Howe C. A spectrophotometric method for measuring hemoglobin in erythroleukemic cells (K562). J Histochem Cytochem 1981; 29: 1442-1444.
13. Grusch M, Fritzer-Szekeres M, Fuhrmann G, Rosenberger G, Luxbacher C, Elford HL, et al. Activation of caspases and induction of apoptosis by novel ribonucleotide reductase inhibitors amidox and didox. Exp Hematol 2001; 29: 623-632.
14. Nakatani N, Ichimaru, M, Moriyasu M, Kato A. Induction of apoptosis in human promyelocytic leukemia cell line HL-60 by C-benzylated dihydrochalcones, uvaretin, isouvaretin and diuvaretin. Biol Pharm Bull 2005; 28: 83-86.
15. Wick MM. Levodopa and dopamine analogs: melanin precursors as antitumor agents in experimental human and murine leukemia. Cancer Treat Rep 1979; 63: 991-997.
16. Kawase M, Motohashi N, Kurihara T, Inagaki M, Satoh K, Sakagami H. Relationship between radical intensity and cytotoxic activity of dopamine-related compounds. Anticancer Res 1998; 18: 1069-1074.
17. Levay G, Bodell WJ. Detection of dopamine - DNA adducts: potential role in Parkinson's disease. Carcinogenesis 1993; 14: 1241-1245.
18. Terasaka H, Tamura A, Takayama F, Kashimata M, Ohtomo K, Machino M, et al. Induction of apoptosis by dopamine in human oral tumor cell lines. Anticancer Res 2000; 20: 243-250.
19. An JJ, Cho SR, Jeong DW, Park KW, Ahm YS, Baik JH, et al. Anti-proliferative effects and cell death mediated by two isoforms of dopamine D2 receptors in pituitary tumor cells. Mol Cell Endocrinol 2003; 206: 49-62.
20. Chen J, Wersinger C, Sidhu A. Chronic stimulation of D1 dopamine receptors in human SK-N-MC neuroblastoma cells induces nitric-oxide synthase activation and cytotoxicity. J Biol Chem 2003; 278: 28089-28100.
21. Sokoloff P, Riou JF, Martres MP, Schwartz JC. Presence of dopamine D-2 receptors in human tumoral cell lines. Biochem Biophys Res Commun 1989; 162: 575-582.