Natural product-based 6-hydroxy-2,3,4,6-tetrahydropyrrolo[1,2-a] pyrimidinium scaffold as a new antifungal template

ACS Medicinal Chemistry Letters

Volumn 2, Issue 5, 2011, Pages 391-395

  Li, Xing Cong ^a,b   Babu, K Suresh ^a   Jacob, Melissa R ^a   Khan, Shabana I ^a,b   Agarwal, Ameeta K ^a   Clark, Alice M ^a,b  

^a UNIVERSITY OF MISSISSIPPI   (United States)

^b UNIVERSITY OF MISSISSIPPI   (United States)

Author keywords

antifungal template; fungicidal; mycosis; Phloeodictines

Indexed keywords

6 DECYL 6 HYDROXY 1 METHYL 2,3,4,6 TETRAHYDROPYRROLO[1,2-A]PYRIMIDINIUM IODIDE; 6 DODECYL 6 HYDROXY 1 METHYL 2,3,4,6 TETRAHYDROPYRROLO[1,2-A]PYRIMIDINIUM IODIDE; 6 HEXADECYL 6 HYDROXY 1 METHYL 2,3,4,6 TETRAHYDROPYRROLO[1,2-A]PYRIMIDINIUM IODIDE; 6 HEXYL 6 HYDROXY 1 METHYL 2,3,4,6 TETRAHYDROPYRROLO[1,2-A]PYRIMIDINIUM IODIDE; 6 HYDROXY 1 METHYL 6 OCTADECYL 2,3,4,6 TETRAHYDROPYRROLO[1,2-A]PYRIMIDINIUM IODIDE; 6 HYDROXY 1 METHYL 6 TETRADECYL 2,3,4,6 TETRAHYDROPYRROLO[1,2-A]PYRIMIDINIUM IODIDE; 6 HYDROXY 2,3,4,6 TETRAHYDROPYRROLO[1,2-A]PYRIMIDINIUM; ANTIFUNGAL AGENT; NATURAL PRODUCT; UNCLASSIFIED DRUG;

ARTICLE; ASPERGILLUS FUMIGATUS; CANDIDA ALBICANS; CONTROLLED STUDY; CRYPTOCOCCUS NEOFORMANS; CYTOTOXICITY; FUNGAL VIRULENCE; FUNGICIDAL ACTIVITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PHARMACOPHORE; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

EID: 79956145677     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/ml200020h     Document Type: Article

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