An activity-based probe for high-throughput measurements of triacylglycerol lipases

Analytical Biochemistry

Volumn 414, Issue 2, 2011, Pages 254-260

  Tam, John ^a   Henault, Martin ^a   Li, Lianhai ^a   Wang, Zhaoyin ^a   Partridge, Anthony W ^a   Melnyk, Roman A ^a  

^a MERCK FROSST CENTRE FOR THERAPEUTIC RESEARCH   (Canada)

Author keywords

Active site ELISA; Activity based probe; Cholesterol; HDL; Occupancy; Reversibility

Indexed keywords

AMINO ACIDS; ANTIBODIES; CHEMICAL DETECTION; CHOLESTEROL; DIAGNOSIS; DISEASE CONTROL; ENZYME INHIBITION; GLYCEROL; LIPOPROTEINS;

ACTIVE SITE; ACTIVITY-BASED PROBE; CARDIO-VASCULAR DISEASE; HIGH THROUGHPUT SCREENING; HIGH-THROUGHPUT MEASUREMENTS; OCCUPANCY; REVERSIBILITY; SMALL MOLECULE INHIBITOR;

PROBES;

ENDOTHELIAL LIPASE; LIPOPROTEIN LIPASE; LIVER TRIACYLGLYCEROL LIPASE; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG;

ANTIBODY AFFINITY; ARTICLE; BIOTINYLATION; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME LINKED IMMUNOSORBENT ASSAY; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; MECHANICAL PROBE; PRIORITY JOURNAL; TITRIMETRY;

EID: 79956110770     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2011.03.008     Document Type: Article

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