Expansion of CD4+CD25+ regulatory T cells from cord blood CD4+ cells using the common γ-chain cytokines (IL-2 and IL-15) and rapamycin

Annals of Hematology

Volumn 90, Issue 6, 2011, Pages 617-624

  Asanuma, Shinsuke ^a   Tanaka, Junji ^a   Sugita, Junichi ^a   Kosugi, Mizuha ^a   Shiratori, Souichi ^a   Wakasa, Kentarou ^a   Shono, Yusuke ^a   Shigematsu, Akio ^a   Kondo, Takeshi ^a   Kobayashi, Takahiko ^a   Asaka, Masahiro ^a   Imamura, Masahiro ^a  

^a HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Cord blood; IL 15; IL 2; Rapamycin; Regulatory T cells

Indexed keywords

CD4 ANTIGEN; INTERLEUKIN 15; INTERLEUKIN 2; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN PIM2; PROTEIN SERINE THREONINE KINASE; RAPAMYCIN; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR; UNCLASSIFIED DRUG;

ARTICLE; CD4+ CD25+ T LYMPHOCYTE; CELL EXPANSION; CONTROLLED STUDY; DRUG MECHANISM; GENE EXPRESSION; HUMAN; HUMAN CELL; MIXED LYMPHOCYTE CULTURE; PRIORITY JOURNAL; PROTEIN FUNCTION; REGULATORY T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; UMBILICAL CORD BLOOD;

ANTIGENS, CD4; CD4-POSITIVE T-LYMPHOCYTES; CELL CULTURE TECHNIQUES; CELL PROLIFERATION; CELLS, CULTURED; DRUG COMBINATIONS; FETAL BLOOD; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; HUMANS; INTERLEUKIN RECEPTOR COMMON GAMMA SUBUNIT; INTERLEUKIN-15; INTERLEUKIN-2; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; SIROLIMUS; T-LYMPHOCYTES, REGULATORY;

EID: 79956097598     PISSN: 09395555     EISSN: 14320584     Source Type: Journal    
DOI: 10.1007/s00277-010-1121-z     Document Type: Article

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