Electroacupuncture at ST-36 relieves visceral hypersensitivity and decreases 5-HT3 receptor level in the colon in chronic visceral hypersensitivity rats

International Journal of Colorectal Disease

Volumn 26, Issue 5, 2011, Pages 569-574

  Chu, Dan ^a   Cheng, Pengfei ^a   Xiong, Huiling ^a   Zhang, Junjun ^a   Liu, Shi ^a   Hou, Xiaohua ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

5 HT3 receptor; Colorectal distension; Electroacupuncture; ST 36; Visceral hypersensitivity

Indexed keywords

MESSENGER RNA; SEROTONIN 3 RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHRONIC DISEASE; COLON DILATATION; COLON DISEASE; COLORECTAL DISEASE; CONTROLLED STUDY; ELECTROACUPUNCTURE; ELECTROMYOGRAM; HYPERSENSITIVITY; MALE; NEWBORN; NONHUMAN; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ACUPUNCTURE POINTS; ANIMALS; CHRONIC DISEASE; COLON; ELECTROACUPUNCTURE; ELECTROMYOGRAPHY; GENE EXPRESSION REGULATION; HYPERSENSITIVITY; MALE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, SEROTONIN, 5-HT3; RNA, MESSENGER; VISCERA;

EID: 79956089669     PISSN: 01791958     EISSN: 14321262     Source Type: Journal    
DOI: 10.1007/s00384-010-1087-2     Document Type: Article

References (22)

1. Kuiken SD, Tytgat GN, Boeckxstaens GE (2005) Review article: drugs interfering with visceral sensitivity for the treatment of functional gastrointestinal disorders - the clinical evidence. Aliment Pharmacol Ther 21:633-651 (Pubitemid 40468992)
2. Cui KM, Li WM, Gao X, Chung K, Chung JM, Wu JC (2005) Electro-acupuncture relieves chronic visceral hyperalgesia in rats. Neurosci Lett 376:20-23 (Pubitemid 40202930)
3. Tian XY, Bian ZX, Hu XG, Zhang XJ, Liu L, Zhang HQ (2006) Electro-acupuncture attenuates stress-induced defecation in rats with chronic visceral hypersensitivity via serotonergic pathway. Brain Res 1088:101-108 (Pubitemid 43729413)
4. Ulett GA, Han S, Han JS (1998) Electroacupuncture: mechanisms and clinical application. Biol Psychiatry 44:129-138 (Pubitemid 28305532)
5. Lux G, Hagel J, Bäcker P, Bäcker G, Vogl R, Ruppin H, Domschke S, Domschke W (1994) Acupuncture inhibits vagal gastric acid secretion stimulated by sham feeding in healthy subjects. Gut 35:1026-1029 (Pubitemid 24244252)
6. Espejo EF, Gil E (1998) Antagonism of perpheral 5-HT4 receptors reduces visceral and cutaneous pain in mice and induces visceral an algesia after simultaneous inactivation of 5-HT3 receptors. Brain Res 788:20-24 (Pubitemid 28202139)
7. Koziowski CM, Green A, Grundy D, Boissonade FM, Bountra C (2000) The 5-HT(3) receptor antagonist alosetron inhibits the colorectal distention induced depressor response and spinal c-fos expression in the anesthetised rat. Gut 46:474-480 (Pubitemid 30305810)
8. Winston J, Shenoy M, Medley D, Naniwadekar A, Pasricha PJ (2007) The vanilloid receptor initiates and maintains colonic hypersensitivity induced by neonatal colon irritation in rats. Gastroenterology 132:615-627 (Pubitemid 46274656)
9. Mayer EA, Collins SM (2002) Evolving pathophysiologic models of functional gastrointestinal disorders. Gastroenterology 122:2032-2048 (Pubitemid 34651445)
10. Al-chaer ED, Kawasaki M, Pasricha PJ (2000) A new model of chronic visceral hypersensitivity in adult rats induced by colon irritation during postnatal development. Gastroenterology 119:1276-1285
11. La JH, Kim TW, Sung TS, Kang JW, Kim HJ, Yang IS (2003) Visceral hypersensitivity and altered colonic motility after subsidence of inflammation in a rat model of colitis. World J Gastroenterol 9:2791-2795
12. Xu GY, Winston JH, Chen JD (2009) Electroacupuncture attenuates visceral hyperalgesia and inhibits the enhanced excitability of colon specific sensory neurons in a rat model of IBS. Neurogastroenterol Motil 21:1302-e125
13. Ezzo J, Berman B, Hadhazy VA, Jadad AR, Lao L, Singh BB (2000) Is acupuncture effective for the treatment of chronic pain? A systematic review. Pain 86:217-225 (Pubitemid 30254262)
14. Tian SL, Wang XY, Ding GH (2008) Repeated electroacupuncture attenuates chronic visceral hypersensitivity and spinal cord NMDA receptor phosphorylation in a rat irritable bowel syndrome model. Life Sci 83:356-363
15. Iwa M, Strickland C, Nakade Y, Pappas TN, Takahashi T (2005) Electroacupuncture reduces rectal distension-induced blood pressure changes in conscious dogs. Dig Dis Sci 50:1264-1270 (Pubitemid 41184753)
16. McLean PG, Borman RA, Lee K (2007) 5-HT in the enteric nervous system: gut function and neuropharmacology. Trends Neurosci 30:9-13 (Pubitemid 46001679)
17. Liu HR, Wang XM, Zhou EH, Shi Y, Li N, Yuan LS, Wu HG (2009) Acupuncture at both ST 25 and ST37 improves the pain threshold of chronic visceral hypersensitivity rats. Neurochem Res 34(11):1914-1918
18. Zhou EH, Liu HR, Wu HG, Shi Y, Wang XM, Tan LY, Yao LQ, Zhong YS, Jiang Y, Zhang LL (2009) Suspended moxibustion relieves chronic visceral hyperalgesia via serotonin pathway in the colon. Neurosci Lett 451(2):144-147
19. Crowell MD (2004) Role of serotonin in the pathophysiology of the irritable bowel syndrome. Br J Pharmacol 141:1285-1293
20. Prior A, Read NW (1993) Reduction of rectal sensitivity and postprandial motility by granisetron, a 5HT3-receptor antagonist, in patients with irritable bowel syndrome. Aliment Pharmacol Ther 7:175-180 (Pubitemid 23109464)
21. Delvaux M, Louvel D, Marmet JP, Campos-Oriola R, Frexinos J (1998) Effect of alosetron on responses to colonic distension in patients with irritable bowel syndrome. Aliment Pharmacol Ther 12:849-855 (Pubitemid 28428949)
22. Ma XP, Tan LY, Yang Y, Wu HG, Jiang B, Liu HR, Yang L (2009) Effect of electro-acupuncture on substance P, its receptor and corticotropin-releasing hormone in rats with irritable bowel syndrome. World J Gastroenterol 15(41):5211-5217