메뉴 건너뛰기




Volumn 34, Issue 3, 2011, Pages 198-202

Thymosin alpha 1 is associated with improved cellular immunity and reduced infection rate in severe acute pancreatitis patients in a double-blind randomized control study

Author keywords

CD4 CD8 ratio; HLA DR; infection; severe acute pancreatitis; thymosin alpha 1

Indexed keywords

C REACTIVE PROTEIN; HLA DR ANTIGEN; THYMOSIN ALPHA1;

EID: 79956079157     PISSN: 03603997     EISSN: 15732576     Source Type: Journal    
DOI: 10.1007/s10753-010-9224-1     Document Type: Article
Times cited : (21)

References (21)
  • 1
    • 0029900166 scopus 로고    scopus 로고
    • Surgical strategy and management of infected pancreatic necrosis
    • DOI 10.1002/bjs.1800830714
    • Farkas, G., J. Marton, Y. Mandi, et al. 1996. Surgical strategy and management of infected pancreatic necrosis. The British Journal of Surgery 83: 930-933. (Pubitemid 26228206)
    • (1996) British Journal of Surgery , vol.83 , Issue.7 , pp. 930-933
    • Farkas, G.1    Marton, J.2    Mandi, Y.3    Szederkenyi, E.4
  • 2
    • 0032782449 scopus 로고    scopus 로고
    • Bacterial infection and extent of necrosis are determinants of organ failure in patients with acute necrotizing pancreatitis
    • DOI 10.1046/j.1365-2168.1999.01176.x
    • Isenmann, R., B. Rau, and H.G. Beger. 1999. Bacterial infection and extent of necrosis are determinants of organ failure in patients with acute necrotizing pancreatitis. The British Journal of Surgery 86: 1020-1024. (Pubitemid 29387067)
    • (1999) British Journal of Surgery , vol.86 , Issue.8 , pp. 1020-1024
    • Isenmann, R.1    Rau, B.2    Beger, H.G.3
  • 3
    • 0021952498 scopus 로고
    • Prognostic significance of the absolute lymphocyte count in acute pancreatitis
    • DOI 10.1016/0002-9610(85)90063-7
    • Christophi, C., F. McDermott, and E.S. Hughes. 1985. Prognostic significance of the absolute lymphocyte count in acute pancreatitis. American Journal of Surgery 150: 295-296. (Pubitemid 15242518)
    • (1985) American Journal of Surgery , vol.150 , Issue.3 , pp. 295-296
    • Christophi, C.1    McDermott, F.2    Hughes, E.S.R.3
  • 4
    • 0027455178 scopus 로고
    • Reduction in circulating levels of CD4-positive lymphocytes in acute pancreatitis: Relationship to endotoxin, interleukin 6 and disease severity
    • DOI 10.1002/bjs.1800801031
    • Curley, P.J., M.J. McMahon, F. Lancaster, et al. 1993. Reduction in circulating levels of CD4-positive lymphocytes in acute pancreatitis: relationship to endotoxin, interleukin 6 and disease severity. The British Journal of Surgery 80: 1312-1315. (Pubitemid 23313170)
    • (1993) British Journal of Surgery , vol.80 , Issue.10 , pp. 1312-1315
    • Curley, P.J.1    McMahon, M.J.2    Lancaster, F.3    Banks, R.E.4    Barclay, G.R.5    Shefta, J.6    Boylston, A.W.7    Whicher, J.T.8
  • 5
    • 0029034636 scopus 로고
    • Circulating lymphocyte subsets in human acute pancreatitis
    • Pezzilli, R., P. Billi, E. Beltrandi, et al. 1995. Circulating lymphocyte subsets in human acute pancreatitis. Pancreas 11: 95-100.
    • (1995) Pancreas , vol.11 , pp. 95-100
    • Pezzilli, R.1    Billi, P.2    Beltrandi, E.3
  • 6
    • 0030006542 scopus 로고    scopus 로고
    • Immune function early in acute pancreatitis
    • DOI 10.1002/bjs.1800830514
    • Widdison, A.L., and S. Cunningham. 1996. Immune function early in acute pancreatitis. The British Journal of Surgery 83: 633-636. (Pubitemid 26166174)
    • (1996) British Journal of Surgery , vol.83 , Issue.5 , pp. 633-636
    • Widdison, A.L.1    Cunningham, S.2
  • 8
    • 34948901873 scopus 로고    scopus 로고
    • Thymosin alpha 1 improves severe acute pancreatitis in rats via regulation of peripheral T cell number and cytokine serum level
    • DOI 10.1111/j.1440-1746.2006.04699.x
    • Yao, W., Q. Zhu, Y. Yuan, et al. 2007. Thymosin alpha 1 improves severe acute pancreatitis in rats via regulation of peripheral T cell number and cytokine serum level. Journal of Gastroenterology and Hepatology 22: 1866-1871. (Pubitemid 47525068)
    • (2007) Journal of Gastroenterology and Hepatology , vol.22 , Issue.11 , pp. 1866-1871
    • Yao, W.1    Zhu, Q.2    Yuan, Y.3    Qiao, M.4    Zhang, Y.5    Zhai, Z.6
  • 9
    • 0344906176 scopus 로고    scopus 로고
    • Thymic atrophy caused by thymocyte apoptosis in experimental severe acute pancreatitis
    • DOI 10.1006/jsre.1998.5360
    • Takeyama, Y., J. Nishikawa, T. Ueda, et al. 1998. Thymic atrophy caused by thymocyte apoptosis in experimental severe acute pancreatitis. The Journal of Surgical Research 78: 97-102. (Pubitemid 28419218)
    • (1998) Journal of Surgical Research , vol.78 , Issue.2 , pp. 97-102
    • Takeyama, Y.1    Nishikawa, J.2    Ueda, T.3    Hori, Y.4
  • 10
    • 0036233026 scopus 로고    scopus 로고
    • Splenic atrophy in experimental severe acute pancreatitis
    • DOI 10.1097/00006676-200205000-00007
    • Yasuda, T., Y. Takeyama, T. Ueda, et al. 2002. Splenic atrophy in experimental severe acute pancreatitis. Pancreas 24: 365-372. (Pubitemid 34441917)
    • (2002) Pancreas , vol.24 , Issue.4 , pp. 365-372
    • Yasuda, T.1    Takeyama, Y.2    Ueda, T.3    Takase, K.4    Nishikawa, J.5    Kuroda, Y.6
  • 11
    • 0034218107 scopus 로고    scopus 로고
    • Peripheral lymphocyte reduction in severe acute pancreatitis is caused by apoptotic cell death
    • Takeyama, Y., K. Takas, T. Ueda, et al. 2000. Peripheral lymphocyte reduction in severe acute pancreatitis is caused by apoptotic cell death. Journal of Gastrointestinal Surgery 4: 379-387.
    • (2000) Journal of Gastrointestinal Surgery , vol.4 , pp. 379-387
    • Takeyama, Y.1    Takas, K.2    Ueda, T.3
  • 12
    • 0027254390 scopus 로고
    • A clinically based classification system for acute pancreatitis
    • Summary of the International Symposium on Acute Pancreatitis, Atlanta, Ga, September 11 through 13, 1992
    • Bradley 3rd, E.L. 1993. A clinically based classification system for acute pancreatitis. Summary of the International Symposium on Acute Pancreatitis, Atlanta, Ga, September 11 through 13, 1992. Archives of Surgery 128: 586-590.
    • (1993) Archives of Surgery , vol.128 , pp. 586-590
    • Bradley III, E.L.1
  • 13
    • 58349089304 scopus 로고    scopus 로고
    • A new immunomodulatory therapy for severe sepsis: Ulinastatin Plus Thymosin alpha 1
    • Li, Y., H. Chen, X. Li, et al. 2009. A new immunomodulatory therapy for severe sepsis: Ulinastatin Plus Thymosin alpha 1. Journal of Intensive Care Medicine 24: 47-53.
    • (2009) Journal of Intensive Care Medicine , vol.24 , pp. 47-53
    • Li, Y.1    Chen, H.2    Li, X.3
  • 16
    • 0033837715 scopus 로고    scopus 로고
    • Severe acute pancreatitis causes alterations in HLA-DR and CD14 expression on peripheral blood monocytes independently of surgical treatment
    • Gotzinger, P., T. Sautner, A. Spittler, et al. 2000. Severe acute pancreatitis causes alterations in HLA-DR and CD14 expression on peripheral blood monocytes independently of surgical treatment. The European Journal of Surgery 166: 628-632. (Pubitemid 30663779)
    • (2000) European Journal of Surgery , vol.166 , Issue.8 , pp. 628-632
    • Gotzinger, P.1    Sautner, T.2    Spittler, A.3    Barlan, M.4    Wamser, P.5    Roth, E.6    Jakesz, R.7    Fugger, R.8
  • 19
    • 0141923125 scopus 로고    scopus 로고
    • Decreased HLA (human leucocyte antigen)-DR expression on peripheral blood monocytes predicts the development of organ failure in patients with acute pancreatitis
    • Mentula, P., M.L. Kylanpaa-Back, E. Kemppainen, et al. 2003. Decreased HLA (human leucocyte antigen)-DR expression on peripheral blood monocytes predicts the development of organ failure in patients with acute pancreatitis. Clin Sci (Lond) 105: 409-417.
    • (2003) Clin Sci (Lond) , vol.105 , pp. 409-417
    • Mentula, P.1    Kylanpaa-Back, M.L.2    Kemppainen, E.3
  • 20
    • 0032588116 scopus 로고    scopus 로고
    • Thymosinalpha1 stimulates maturation of CD34+ stem cells into CD3+4+ cells in an in vitro thymic epithelia organ coculture model
    • Knutsen, A.P., J.J. Freeman, K.R. Mueller, et al. 1999. Thymosinalpha1 stimulates maturation of CD34+ stem cells into CD3+4+ cells in an in vitro thymic epithelia organ coculture model. International Journal of Immunopharmacology 21: 15-26.
    • (1999) International Journal of Immunopharmacology , vol.21 , pp. 15-26
    • Knutsen, A.P.1    Freeman, J.J.2    Mueller, K.R.3
  • 21
    • 0036785196 scopus 로고    scopus 로고
    • Human leukocyte antigen-DR expression on peripheral monocytes as a predictive marker of sepsis during acute pancreatitis
    • Satoh, A., T. Miura, K. Satoh, et al. 2002. Human leukocyte antigen-DR expression on peripheral monocytes as a predictive marker of sepsis during acute pancreatitis. Pancreas 25: 245-250.
    • (2002) Pancreas , vol.25 , pp. 245-250
    • Satoh, A.1    Miura, T.2    Satoh, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.