Differential expression of S6K2 dictates tissue-specific requirement for S6K1 in mediating aberrant mTORC1 signaling and tumorigenesis

Cancer Research

Volumn 71, Issue 10, 2011, Pages 3669-3675

  Nardella, Caterina ^a   Lunardi, Andrea ^a   Fedele, Giuseppe ^b   Clohessy, John G ^a   Alimonti, Andrea ^a   Kozma, Sara C ^d   Thomas, George ^d   Loda, Massimo ^b,c,e   Pandolfi, Pier Paolo ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b DANA FARBER CANCER INSTITUTE   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^e MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; S6 KINASE; S6 KINASE 1; S6 KINASE 2; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CONTROLLED STUDY; ENZYME INACTIVATION; GENE DELETION; HETEROZYGOSITY; HUMAN; HUMAN TISSUE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHEOCHROMOCYTOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TISSUE SPECIFICITY; TISSUE TYPES;

ANIMALS; CELL LINE, TUMOR; GENE DELETION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HETEROZYGOTE; HUMANS; MICE; MICE, TRANSGENIC; PHEOCHROMOCYTOMA; PROTEINS; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA;

EID: 79956072554     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-10-3962     Document Type: Article

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