Imipramine activates glial cell line-derived neurotrophic factor via early growth response gene 1 in astrocytes

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Volumn 35, Issue 4, 2011, Pages 1026-1032

  Kim, Yeni ^a   Kim, Se Hyun ^b   Kim, Yong Sik ^a,b   Lee, Young Han ^c   Ha, Kyooseob ^a,d   Shin, Soon Young ^c  

^a Seoul National University Hospital   (South Korea)

^b Seoul National University College of Medicine   (South Korea)

^c Konkuk University   (South Korea)

^d Seoul National University Bundang Hospital   (South Korea)

Author keywords

Antidepressants; Astrocytes; Early growth response 1; Glial cell line derived neurotrophic factor; Imipramine

Indexed keywords

EARLY GROWTH RESPONSE FACTOR 1; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; GLIAL FIBRILLARY ACIDIC PROTEIN; IMIPRAMINE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ARTICLE; ASTROCYTE; BINDING SITE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; EARLY GROWTH RESPONSE 1 GENE; ENZYME PHOSPHORYLATION; GENE; GENE ACTIVATION; GENE OVEREXPRESSION; GENE SILENCING; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR GENE; IMMUNOREACTIVITY; NONHUMAN; PROMOTER REGION; PROTEIN EXPRESSION; RAT; TRANSCRIPTION REGULATION; UPREGULATION;

ANIMALS; ANTIDEPRESSIVE AGENTS, TRICYCLIC; ASTROCYTES; BLOTTING, WESTERN; CELLS, CULTURED; EARLY GROWTH RESPONSE PROTEIN 1; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; IMIPRAMINE; LUCIFERASES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, CONFOCAL; MITOGEN-ACTIVATED PROTEIN KINASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC; UP-REGULATION;

EID: 79956018806     PISSN: 02785846     EISSN: 18784216     Source Type: Journal    
DOI: 10.1016/j.pnpbp.2011.02.012     Document Type: Article

References (36)

1. Beckmann A.M., Wilce P.A. Egr transcription factors in the nervous system. Neurochem Int 1997, 31:477-510. discussion 7-6.
2. Carnicella S., Ron D. GDNF-a potential target to treat addiction. Pharmacol Ther 2009, 122:9-18.
3. Choi B.H., Kim C.G., Bae Y.S., Lim Y., Lee Y.H., Shin S.Y. p21 Waf1/Cip1 expression by curcumin in U-87MG human glioma cells: role of early growth response-1 expression. Cancer Res 2008, 68:1369-1377.
4. Chung E.Y., Shin S.Y., Lee Y.H. Amitriptyline induces early growth response-1 gene expression via ERK and JNK mitogen-activated protein kinase pathways in rat C6 glial cells. Neurosci Lett 2007, 422:43-48.
5. Conti B., Maier R., Barr A.M., Morale M.C., Lu X., Sanna P.P., et al. Region-specific transcriptional changes following the three antidepressant treatments electro convulsive therapy, sleep deprivation and fluoxetine. Mol Psychiatry 2007, 12:167-189.
6. Dahmen N., Fehr C., Reuss S., Hiemke C. Stimulation of immediate early gene expression by desipramine in rat brain. Biol Psychiatry 1997, 42:317-323.
7. Eslamboli A., Georgievska B., Ridley R.M., Baker H.F., Muzyczka N., Burger C., et al. Continuous low-level glial cell line-derived neurotrophic factor delivery using recombinant adeno-associated viral vectors provides neuroprotection and induces behavioral recovery in a primate model of Parkinson's disease. J Neurosci 2005, 25:769-777.
8. Georgievska B., Kirik D., Bjorklund A. Overexpression of glial cell line-derived neurotrophic factor using a lentiviral vector induces time- and dose-dependent downregulation of tyrosine hydroxylase in the intact nigrostriatal dopamine system. J Neurosci 2004, 24:6437-6445.
9. Georgievska B., Kirik D., Rosenblad C., Lundberg C., Bjorklund A. Neuroprotection in the rat Parkinson model by intrastriatal GDNF gene transfer using a lentiviral vector. NeuroReport 2002, 13:75-82.
10. Gerlai R., McNamara A., Choi-Lundberg D.L., Armanini M., Ross J., Powell-Braxton L., et al. Impaired water maze learning performance without altered dopaminergic function in mice heterozygous for the GDNF mutation. Eur J Neurosci 2001, 14:1153-1163.
11. Golan M., Schreiber G., Avissar S. Antidepressants elevate GDNF expression and release from C6 glioma cells in a beta-arrestin1-dependent, CREB interactive pathway. Int J Neuropsychopharmacol 2011, 1-12.
12. Hisaoka K., Maeda N., Tsuchioka M., Takebayashi M. Antidepressants induce acute CREB phosphorylation and CRE-mediated gene expression in glial cells: a possible contribution to GDNF production. Brain Res 2008, 1196:53-58.
13. Hisaoka K., Nishida A., Koda T., Miyata M., Zensho H., Morinobu S., et al. Antidepressant drug treatments induce glial cell line-derived neurotrophic factor (GDNF) synthesis and release in rat C6 glioblastoma cells. J Neurochem 2001, 79:25-34.
14. Johansson I.M., Bjartmar L., Marcusson J., Ross S.B., Seckl J.R., Olsson T. Chronic amitriptyline treatment induces hippocampal NGFI-A, glucocorticoid receptor and mineralocorticoid receptor mRNA expression in rats. Brain Res Mol Brain Res 1998, 62:92-95.
15. Jung H.Y., Kang U.G., Ahn Y.M., Joo Y.H., Park J.B., Kim Y.S. Induction of tetradecanoyl phorbol acetate-inducible sequence (TIS) genes by electroconvulsive shock in rat brain. Biol Psychiatry 1996, 40:503-507.
16. Klawitter J., Gottschalk S., Hainz C., Leibfritz D., Christians U., Serkova N.J. Immunosuppressant neurotoxicity in rat brain models: oxidative stress and cellular metabolism. Chem Res Toxicol 2010, 23:608-619.
17. Laganiere J., Kells A.P., Lai J.T., Guschin D., Paschon D.E., Meng X., et al. An engineered zinc finger protein activator of the endogenous glial cell line-derived neurotrophic factor gene provides functional neuroprotection in a rat model of Parkinson's disease. J Neurosci 2010, 30:16469-16474.
18. Lee S.L., Wang Y., Milbrandt J. Unimpaired macrophage differentiation and activation in mice lacking the zinc finger transplantation factor NGFI-A (EGR1). Mol Cell Biol 1996, 16:4566-4572.
19. Lin L.F., Doherty D.H., Lile J.D., Bektesh S., Collins F. GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons. Science 1993, 260:1130-1132.
20. Lorains F.K., Cowlishaw S., Thomas S.A. Prevalence of comorbid disorders in problem and pathological gambling: systematic review and meta-analysis of population surveys. Addiction 2011, 106:490-498.
21. Lyne J.P., O'Donoghue B., Clancy M., O'Gara C. Comorbid psychiatric diagnoses among individuals presenting to an addiction treatment program for alcohol dependence. Subst Use Misuse 2011, 46:351-358.
22. Messer C.J., Eisch A.J., Carlezon W.A., Whisler K., Shen L., Wolf D.H., et al. Role for GDNF in biochemical and behavioral adaptations to drugs of abuse. Neuron 2000, 26:247-257.
23. Niwa M., Nitta A., Yamada Y., Nakajima A., Saito K., Seishima M., et al. An inducer for glial cell line-derived neurotrophic factor and tumor necrosis factor-alpha protects against methamphetamine-induced rewarding effects and sensitization. Biol Psychiatry 2007, 61:890-901.
24. O'Donovan K.J., Wilkens E.P., Baraban J.M. Sequential expression of Egr-1 and Egr-3 in hippocampal granule cells following electroconvulsive stimulation. J Neurochem 1998, 70:1241-1248.
25. Otsuki K., Uchida S., Watanuki T., Wakabayashi Y., Fujimoto M., Matsubara T., et al. Altered expression of neurotrophic factors in patients with major depression. J Psychiatr Res 2008, 42:1145-1153.
26. Sanchez B., Lopez-Martin E., Segura C., Labandeira-Garcia J.L., Perez-Fernandez R. 1, 25-Dihydroxyvitamin D(3) increases striatal GDNF mRNA and protein expression in adult rats. Brain Res Mol Brain Res 2002, 108:143-146.
27. Schreiber G., Golan M., Avissar S. Beta-arrestin signaling complex as a target for antidepressants and as a depression marker. Drug News Perspect 2009, 22:467-480.
28. Shin S.Y., Bahk Y.Y., Ko J., Chung I.Y., Lee Y.S., Downward J., et al. Suppression of Egr-1 transcription through targeting of the serum response factor by oncogenic H-Ras. EMBO J 2006, 25:1093-1103.
29. Shin S.Y., Song H., Kim C.G., Choi Y.K., Lee K.S., Lee S.J., et al. Egr-1 is necessary for fibroblast growth factor-2-induced transcriptional activation of the glial cell line-derived neurotrophic factor in murine astrocytes. J Biol Chem 2009, 284:30583-30593.
30. Slattery D.A., Morrow J.A., Hudson A.L., Hill D.R., Nutt D.J., Henry B. Comparison of alterations in c-fos and Egr-1 (zif268) expression throughout the rat brain following acute administration of different classes of antidepressant compounds. Neuropsychopharmacology 2005, 30:1278-1287.
31. Takebayashi M., Hisaoka K., Nishida A., Tsuchioka M., Miyoshi I., Kozuru T., et al. Decreased levels of whole blood glial cell line-derived neurotrophic factor (GDNF) in remitted patients with mood disorders. Int J Neuropsychopharmacol 2006, 9:607-612.
32. Tan S.K., Hartung H., Sharp T., Temel Y. Serotonin-dependent depression in Parkinson's disease: a role for the subthalamic nucleus?. Neuropharmacology 2011.
33. Visanji N.P., Orsi A., Johnston T.H., Howson P.A., Dixon K., Callizot N., et al. PYM50028, a novel, orally active, nonpeptide neurotrophic factor inducer, prevents and reverses neuronal damage induced by MPP+in mesencephalic neurons and by MPTP in a mouse model of Parkinson's disease. FASEB J 2008, 22:2488-2497.
34. Weinreb O., Amit T., Bar-Am O., Youdim M.B. Induction of neurotrophic factors GDNF and BDNF associated with the mechanism of neurorescue action of rasagiline and ladostigil: new insights and implications for therapy. Ann NY Acad Sci 2007, 1122:155-168.
35. Zhang X., Zhang Z., Sha W., Xie C., Xi G., Zhou H., et al. Electroconvulsive therapy increases glial cell-line derived neurotrophic factor (GDNF) serum levels in patients with drug-resistant depression. Psychiatry Res 2009, 170:273-275.
36. Zhang X., Zhang Z., Xie C., Xi G., Zhou H., Zhang Y., et al. Effect of treatment on serum glial cell line-derived neurotrophic factor in depressed patients. Prog Neuropsychopharmacol Biol Psychiatry 2008, 32:886-890.