1,25-Dihydroxyvitamin D3 increases striatal GDNF mRNA and protein expression in adult rats

Molecular Brain Research

Volumn 108, Issue 1-2, 2002, Pages 143-146

  Sanchez, Begoña ^a   Lopez Martin, Elena ^a   Segura, Carmen ^a   Labandeira Garcia, Jose L ^a   Perez Fernandez, Roman ^a  

^a UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

Author keywords

1,25 Dihydroxyvitamin D3; GDNF; Parkinson's disease; Rat; Striatum

Indexed keywords

BRAIN PROTEIN; CALCITRIOL; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; MESSENGER RNA; CALCIUM CHANNEL STIMULATING AGENT; GDNF PROTEIN, HUMAN; GDNF PROTEIN, RAT; NERVE GROWTH FACTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; DRUG EFFECT; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; ANIMAL; GENETIC TRANSCRIPTION; GENETICS; HUMAN; METABOLISM; PARKINSON DISEASE; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ANIMALS; CALCITRIOL; CALCIUM CHANNEL AGONISTS; CORPUS STRIATUM; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; HUMANS; NERVE GROWTH FACTORS; PARKINSON DISEASE; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; TRANSCRIPTION, GENETIC;

EID: 1842843362     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(02)00545-4     Document Type: Article

References (18)

1. Björklund A., Rosenblad C., Winkler C., Kirik D. Studies on neuroprotective and regenerative effects of GDNF in a partial lesion model of Parkinson's disease. Neurobiol. Dis. 4:1997;186-200.
2. Connor B., Dragunow M. The role of neuronal growth factors in neurodegenerative disorders of the human brain. Brain Res. Rev. 27:1998;1-39.
3. Gash D.M., Zhang Z., Ovadia A., Cass W.A., Yi A., Simmerman L., Russell D., Martin D., Lapchak P.A., Collins F., Hoffer B.J., Gerhardt G.A. Functional recovery in parkinsonian monkeys treated with GDNF. Nature. 380:1996;252-255.
4. Gil-Puig C., Blanco M., Garcia-Caballero T., Segura C., Perez-Fernandez R. Pit-1/GHF-1 and GH expression in the MCF-7 human breast adenocarcinoma cell line. J. Endocrinol. 173:2002;161-167.
5. Ibi M., Sawada H., Nakanishi M., Kume T., Katsuki H., Kaneko S., Shimohama S., Akaike A. Protective effects of 1alpha,25-(OH)2D3 against the neurotoxicity of glutamate and reactive oxygen species in mesencephalic culture. Neuropharmacology. 40:2001;761-771.
6. Kirik D., Rosenblad C., Björklund A. Preservation of a functional nigrostriatal dopamine pathway by GDNF in the intrastriatal 6-OHDA lesion model depends on the site of administration of the trophic factor. Eur. J. Neurosci. 12:2000;3871-3882.
7. Lin L.F.H., Doherty D.H., Lile J.D., Bektesh S., Collins F. GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons. Science. 260:1993;1130-1132.
8. Lopez-Martin E., Caruncho H., Rodriguez J., Guerra M.J., Labandeira-Garcia J.L. Striatal dopaminergic afferents concentrate in GDNF-positive patches during development and in developing intrastriatal striatal grafts. J. Comp. Neurol. 406:1999;199-206.
9. Nataf S., Garcion E., Darcy F., Chabannes D., Muller J.Y., Brachet P. 1,25-Dihydroxyvitamin D3 exerts regional effects in the central nervous system during experimental allergic encephalomyelitis. J. Neuropathol. Exp. Neurol. 55:1996;904-914.
10. Naveilhan P., Neveu I., Wion D., Brachet P. 1,25-Dihydroxyvitamin D3, an inducer of glial cell line-derived neurotrophic factor. NeuroReport. 7:1996;2171-2175.
11. Prüfer K., Veenstra T.D., Jirikowski G.F., Kumar R. Distribution of 1,25-dihydroxyvitamin D3 receptor immunoreactivity in the rat brain and spinal cord. J. Chem. Neuroanat. 16:1999;135-145.
12. Rachez C., Freedman L.P. Mechanisms of gene regulation by vitamin D3 receptor: a network of coactivator interactions. Gene. 246:2000;9-21.
13. Siegel G.J., Chauhan N.B. Neurotrophic factors in Alzheimer's and Parkinson's disease brain. Brain Res. Rev. 33:2000;199-227.
14. Stumpf W.E., Sar M., Reid F.A., Tanaka Y., DeLuca H.F. Target cells for 1,25-Dihydroxyvitamin D3 in intestinal tract, stomach, kidney, skin, pituitary, and parathyroid. Science. 206:1979;1188-1190.
15. Tomac A., Lindqvist E., Lin L.F.H., Ogren S.O., Young D., Hoffer B.J., Olson L. Protection and repair of the nigrostriatal dopaminergic system by GDNF in vivo. Nature. 373:1995;335-339.
16. Veenstra T.D., Prüfer K., Koenigsberger C., Brimijoin S.W., Grande J.P., Kumar R. 1,25-Dihydroxyvitamin D3 receptors in the central nervous system of the rat embryo. Brain Res. 804:1998;193-205.
17. Wang Y., Chiang Y.H., Su T.P., Hayashi T., Morales M., Hoffer B.J., Lin S.Z. Vitamin D3 attenuates cortical infarction induced by middle cerebral arterial ligation in rats. Neuropharmacology. 39:2000;873-880.
18. Wion D., MacGrogan D., Neveu I., Jehan F., Houlgatte R., Brachet P. 1,25-Dihydroxyvitamin D3 is a potent inducer of nerve growth factor synthesis. J. Neurosci. Res. 28:1991;110-114.