Lipopolysaccharide regulation of toll-like receptor-4 and matrix metalloprotease-9 in human primary corneal fibroblasts

Investigative Ophthalmology and Visual Science

Volumn 52, Issue 5, 2011, Pages 2796-2803

  Wong, Yuk ^a   Sethu, Claire ^a   Louafi, Fethi ^a   Hossain, Parwez ^a,b  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^b SOUTHAMPTON GENERAL HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; CYTOKINE; GAMMA INTERFERON; GELATINASE A; GELATINASE B; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 10; INTERLEUKIN 12P70; INTERLEUKIN 2; INTERLEUKIN 8; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; BACTERIAL INFECTION; CONTROLLED STUDY; CORNEA CELL; CORNEA PERFORATION; CORNEA ULCER; FIBROBLAST; FIBROBLAST CULTURE; HUMAN; HUMAN CELL; KERATITIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

AGED; AGED, 80 AND OVER; BLOTTING, WESTERN; CELLS, CULTURED; CORNEA; CORNEAL ULCER; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; FIBROBLASTS; FLOW CYTOMETRY; HUMANS; LIPOPOLYSACCHARIDES; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MIDDLE AGED; PSEUDOMONAS AERUGINOSA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TOLL-LIKE RECEPTOR 4;

EID: 79955991516     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.10-5459     Document Type: Article

References (37)

1. Kernacki KA, Hobden JA, Hazlett LD, Fridman R, Berk RS. In vivo bacterial protease production during Pseudomonas aeruginosa corneal infection. Invest Ophthalmol Vis Sci. 1995;36:1371-1378.
2. Kernacki KA, Goebel DJ, Poosch MS, Hazlett LD. Early TIMP gene expression after corneal infection with Pseudomonas aeruginosa. Invest Ophthalmol Vis Sci. 1998;39:331-335.
3. Fleiszig SM, Efron N. Conjunctival flora in extended wear of rigid gas permeable contact lenses. Optom Vis Sci. 1992;69:354-357.
4. Fleiszig SM, Efron N, Pier GB. Extended contact lens wear enhances Pseudomonas aeruginosa adherence to human corneal epithelium. Invest Ophthalmol Vis Sci. 1992;33:2908-2916.
5. Willcox MD. Pseudomonas aeruginosa infection and inflammation during contact lens wear: a review. Optom Vis Sci. 2007;84: 273-278.
6. Takeda K, Akira S. Toll receptors and pathogen resistance. Cell Microbiol. 2003;5:143-153.
7. Miyajima S, Akaike T, Matsumoto K, et al. Matrix metalloproteinases induction by pseudomonal virulence factors and inflammatory cytokines in vitro. Microb Pathog. 2001;31:271-281.
8. Ikema K, Matsumoto K, Inomata Y, et al. Induction of matrix metalloproteinases (MMPs) and tissue inhibitors of MMPs correlates with outcome of acute experimental pseudomonal keratitis. Exp Eye Res. 2006;83:1396-1404.
9. Kumagai N, Fukuda K, Fujitsu Y, Lu Y, Chikamoto N, Nishida T. Lipopolysaccharide-induced expression of intercellular adhesion molecule-1 and chemokines in cultured human corneal fibroblasts. Invest Ophthalmol Vis Sci. 2005;46:114-120.
10. Fukuda K, Kumagai N, Yamamoto K, Fujitsu Y, Chikamoto N, Nishida T. Potentiation of lipopolysaccharide-induced chemokine and adhesion molecule expression in corneal fibroblasts by soluble CD14 or LPS-binding protein. Invest Ophthalmol Vis Sci. 2005;46: 3095-3101.
11. Jin X, Qin Q, Lin Z, Chen W, Qu J. Expression of toll-like receptors in the Fusarium solani infected cornea. Curr Eye Res. 2008;33: 319-324.
12. Zhang J, Kumar A, Wheater M, Yu FS. Lack of MD-2 expression in human corneal epithelial cells is an underlying mechanism of lipopolysaccharide (LPS) unresponsiveness. Immunol Cell Biol. 2009;87:141-148.
13. Hornef MW, Normark BH, Vandewalle A, Normark S. Intracellular recognition of lipopolysaccharide by toll-like receptor 4 in intestinal epithelial cells. J Exp Med. 2003;198:1225-1235.
14. Brough D, Rothwell NJ. Caspase-1-dependent processing of prointerleukin-1beta is cytosolic and precedes cell death. J Cell Sci. 2007;120:772-781.
15. Sun Y, Pearlman E. Inhibition of corneal inflammation by the TLR4 antagonist eritoran tetrasodium (E5564). Invest Ophthalmol Vis Sci. 2009;50:1247-1254.
16. Opdenakker G, Masure S, Grillet B, Van DJ. Cytokine-mediated regulation of human leukocyte gelatinases and role in arthritis. Lymphokine Cytokine Res. 1991;10:317-324.
17. Opdenakker G, Masure S, Proost P, Billiau A, Van DJ. Natural human monocyte gelatinase and its inhibitor. FEBS Lett. 1991;284: 73-78.
18. Van RM, Norga K, Masure S, et al. The cytokine-protease connection: identification of a 96-kD THP-1 gelatinase and regulation by interleukin-1 and cytokine inducers. Cytokine. 1991;3: 231-239.
19. Fini ME, Cui TY, Mouldovan A, Grobelny D, Galardy RE, Fisher SJ. An inhibitor of the matrix metalloproteinase synthesized by rabbit corneal epithelium. Invest Ophthalmol Vis Sci. 1991;32:2997-3001.
20. Matsubara M, Zieske JD, Fini ME. Mechanism of basement membrane dissolution preceding corneal ulceration. Invest Ophthalmol Vis Sci. 1991;32:3221-3237.
21. Matsubara M, Girard MT, Kublin CL, Cintron C, Fini ME. Differential roles for two gelatinolytic enzymes of the matrix metalloproteinase family in the remodelling cornea. Dev Biol. 1991;147:425-439.
22. Dong X, Shi W, Zeng Q, Xie L. Roles of adherence and matrix metalloproteinases in growth patterns of fungal pathogens in cornea. Curr Eye Res. 2005;30:613-620.
23. Yang YN, Bauer D, Wasmuth S, Steuhl KP, Heiligenhaus A. Matrix metalloproteinases (MMP-2 and 9) and tissue inhibitors of matrix metalloproteinases (TIMP-1 and 2) during the course of experi-mental necrotizing herpetic keratitis. Exp Eye Res. 2003;77:227-237.
24. Yamamoto K, Kumagai N, Fukuda K, Fujitsu Y, Nishida T. Activation of corneal fibroblast-derived matrix metalloproteinase-2 by tryptase. Curr Eye Res. 2006;31:313-317.
25. Raoust E, Balloy V, Garcia-Verdugo I, Touqui L, Ramphal R, Chignard M. Pseudomonas aeruginosa LPS or flagellin are sufficient to activate TLR-dependent signaling in murine alveolar macrophages and airway epithelial cells. PLoS One. 2009;4:e7259.
26. Berclaz PY, Carey B, Fillipi MD, et al. GM-CSF regulates a PU.1-dependent transcriptional program determining the pulmonary response to LPS. Am J Respir Cell Mol Biol. 2007;36:114-121.
27. Zhang Z, Louboutin JP, Weiner DJ, Goldberg JB, Wilson JM. Human airway epithelial cells sense Pseudomonas aeruginosa infection via recognition of flagellin by Toll-like receptor 5. Infect Immun. 2005;73:7151-7160.
28. Durum SK, Oppenheim JJ. Proinflammatory cytokines and immunity. In: Paul WE, ed. Fundamental Immunology. 3rd ed. New York: Raven Press; 1993:801-835.
29. Xue ML, Willcox MD, Lloyd A, Wakefield D, Thakur A. Regulatory role of IL-1beta in the expression of IL-6 and IL-8 in human corneal epithelial cells during Pseudomonas aeruginosa colonization. Clin Exp Ophthalmol. 2001;29:171-174.
30. Cole N, Krockenberger M, Bao S, Beagley KW, Husband AJ, Willcox M. Effects of exogenous interleukin-6 during Pseudomonas aeruginosa corneal infection. Infect Immun. 2001;69:4116-4119.
31. Kernacki KA, Barrett RP, Hobden JA, Hazlett LD. Macrophage inflammatory protein-2 is a mediator of polymorphonuclear neutrophil influx in ocular bacterial infection. J Immunol. 2000;164: 1037-1045.
32. Yan XT, Tumpey TM, Kunkel SL, Oakes JE, Lausch RN. Role of MIP-2 in neutrophil migration and tissue injury in the herpes simplex virus-1-infected cornea. Invest Ophthalmol Vis Sci. 1998; 39:1854-1862.
33. Thakur A, Barrett RP, McClellan S, Hazlett LD. Regulation of Pseudomonas aeruginosa corneal infection in IL-1 beta converting enzyme (ICE, caspase-1) deficient mice. Curr Eye Res. 2004;29: 225-233.
34. Huang X, McClellan SA, Barrett RP, Hazlett LD. IL-18 contributes to host resistance against infection with Pseudomonas aeruginosa through induction of IFN-gamma production. J Immunol. 2002; 168:5756-5763.
35. Hazlett LD, Rudner XL, McClellan SA, Barrett RP, Lighvani S. Role of IL-12 and IFN-gamma in Pseudomonas aeruginosa corneal infection. Invest Ophthalmol Vis Sci. 2002;43:419-424.
36. Cubitt CL, Lausch RN, Oakes JE. Differential regulation of granulocyte-macrophage colony-stimulating factor gene expression in human corneal cells by proinflammatory cytokines. J Immunol. 1994;153:232-240.
37. Duan R, Remeijer L, van Dun JM, Osterhaus AD, Verjans GM. Granulocyte macrophage colony-stimulating factor expression in human herpetic stromal keratitis: implications for the role of neutrophils in HSK. Invest Ophthalmol Vis Sci. 2007;48:277-284.