Molecular and biochemical mining of heat-shock and 14-3-3 proteins in drug-induced protoscolices of Echinococcus granulosus and the detection of a candidate gene for anthelmintic resistance

Journal of Helminthology

Volumn 85, Issue 2, 2011, Pages 196-203

  Pan, D ^a   Das, S ^a   Bera, A K ^a   Bandyopadhyay, S ^a,b   De, S ^a   Rana, T ^a   Das, S K ^a   Suryanaryana, V V ^a   Deb, J ^c   Bhattacharya, D ^a  

^a INDIAN VETERINARY RESEARCH INSTITUTE   (India)

^b NATIONAL RESEARCH CENTRE ON YAK   (India)

^c R G KAR MEDICAL COLLEGE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ALBENDAZOLE; BENZIMIDAZOLE; BETA TUBULIN; HEAT SHOCK PROTEIN 60; PROTEIN 14 3 3; ANTHELMINTIC AGENT; CHAPERONIN 60; MUTANT PROTEIN; TUBULIN;

ARTICLE; CELL SURVIVAL; ECHINOCOCCOSIS; ECHINOCOCCUS GRANULOSUS; HOUSEKEEPING GENE; NONHUMAN; NUCLEOTIDE SEQUENCE; POINT MUTATION; SIGNAL TRANSDUCTION; AMINO ACID SEQUENCE; ANIMAL; BIOSYNTHESIS; DRUG EFFECTS; DRUG RESISTANCE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; MOLECULAR GENETICS;

ANIMALIA; ECHINOCOCCUS GRANULOSUS;

14-3-3 PROTEINS; AMINO ACID SEQUENCE; ANIMALS; ANTHELMINTICS; CHAPERONIN 60; DRUG RESISTANCE; ECHINOCOCCUS GRANULOSUS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; MOLECULAR SEQUENCE DATA; MUTANT PROTEINS; POINT MUTATION; TUBULIN;

EID: 79955987908     PISSN: 0022149X     EISSN: 14752697     Source Type: Journal    
DOI: 10.1017/S0022149X10000477     Document Type: Article

References (29)

1. Ammann, R. & Eckert, J. (1995) Clinical diagnosis and treatment of echinococcosis in humans. pp. 411-463 in Thompson, R.C.A. & Lymbery, A.J. (Eds) Echinococcus and hydatid disease. Wallingford, UK, CAB International.
2. Brehm, K., Kronthaler, K., Jura, H. & Frosch, M. (2000) Cloning and characterization of beta-tubulin genes from Echinococcus multilocularis. Molecular and Biochemical Parasitology 107, 297-302. (Pubitemid 30211644)
3. Casado, N., Rodriguez-Caabeiro, F. & Fernandez, S. (1986) In vitro survival of Echinococcus granulosus protoscolices in several media, at +4 degrees C and +37 degrees C. Zeitschrift für Parasitenkunde 72, 273-278. (Pubitemid 16154390)
4. Del Razo, L.M., Quintanilla-Vega, B., Brambila- Colombres, E., Calderón-Aranda, E.S., Manno, M. & Albores, A. (2001) Stress proteins induced by arsenic. Toxicology and Applied Pharmacology 177, 132-148. (Pubitemid 34033047)
5. Driscoll, M., Dean, E., Reilly, E., Bergholz, E. & Chalfie, M. (1989) Genetic and molecular analysis of a Caenorhabditis elegans beta-tubulin that conveys benzimidazole sensitivity. Journal of Cell Biology 109, 2993-3003. (Pubitemid 20011924)
6. Elard, L., Comes, A.M. & Humbert, J.F. (1996) Sequences of beta-tubulin cDNA from benzimidazole-susceptible and -resistant strains of Teladorsagia circumcincta, a nematode parasite of small ruminants. Molecular and Biochemical Parasitology 79, 249-253. (Pubitemid 26241898)
7. Feder, M.E. & Hofmann, G.E. (1999) Heat-shock proteins, molecular chaperones, and the stress response: evolutionary and ecological physiology. Annual Review of Physiology 61, 243-282. (Pubitemid 29143171)
8. Fu, H., Subramanian, R.R. & Masters, S.C. (2000) 14-3-3 proteins: structure, function, and regulation. Annual Review of Pharmacology and Toxicology 40, 617-647. (Pubitemid 30340695)
9. Geerts, S. & Gryseels, B. (2000) Drug resistance in human helminths: current situation and lessons from livestock. Clinical Microbiology 13, 207-222. (Pubitemid 30205425)
10. Jung, M.K. & Oakley, B.R. (1990) Identification of an amino acid substitution in the benA, beta-tubulin gene of Aspergillus nidulans that confers thiabendazole resistance and benomyl supersensitivity. Cell Motility and Cytoskeleton 17, 87-94. (Pubitemid 20372176)
11. Kaufmann, S.H. (1992) The cellular immune response to heat shock proteins. Experientia 48, 640-643.
12. Kwa, M.S., Veenstra, J.G. & Roos, M.H. (1993a) Benzimidazole resistance in Haemonchus contortus is correlated with a conserved mutation at amino acid 200 in beta-tubulin isotype 1. Molecular and Biochemical Parasitology 63, 299-303. (Pubitemid 24073839)
13. Kwa, M.S., Veenstra, J.G. & Roos, M.H. (1993b) Molecular characterisation of beta-tubulin genes present in benzimidazole-resistant populations of Haemonchus contortus. Molecular and Biochemical Parasitology 60, 133-143. (Pubitemid 223040830)
14. Kwa, M.S., Veenstra, J.G., Van Dijk, M. & Roos, M.H. (1995) Beta-tubulin genes from the parasitic nematode Haemonchus contortus modulate drug resistance in Caenorhabditis elegans. Journal of Molecular Biology 246, 500-510.
15. Maresca, B. & Kobayashi, G.S. (1994) Hsp70 in parasites: as an inducible protective protein and as an antigen. Experientia 50, 1067-1074.
16. Martínez, J., Pérez-Serrano, J., Bernadina, W.E. & Rodriguez-Caabeiro, F. (1999a) Echinococcus granulosus: in vitro effects of ivermectin and praziquantel on hsp60 and hsp70 levels. Experimental Parasitology 93, 171-180.
17. Martínez, J., Pérez-Serrano, J., Bodega, G., Casado, N. & Rodríguez-Caabeiro, F. (1999b) Heat shock proteins HSP70 and HSP60 in Echinococcus granulosus protoscolices. Folia Parasitologica (Praha) 46, 76-78. (Pubitemid 29198639)
18. Matsumoto, J., Müller, N., Hemphill, A., Oku, Y., Kamiya, M. & Gottstein, B. (2006) 14-3-3 and II/ 3-10-gene expression as molecular markers to address viability and growth activity of Echinococcus multilocularis metacestodes. Parasitology 132, 83-94. (Pubitemid 43053664)
19. Polla, B.S. (1991) Heat shock proteins in host-parasite interactions. Immunology Today 12, 38-41.
20. Roos, M.H., Boersema, J.H., Borgsteede, F.H., Cornelissen, J., Taylor, M. & Ruitenberg, E.J. (1990) Molecular analysis of selection for benzimidazole resistance in the sheep parasite Haemonchus contortus. Molecular and Biochemical Parasitology 43, 77-88. (Pubitemid 20306270)
21. Roos, M.H., Kwa, M.S.G. & Grant, W.N. (1995) New genetic and practical implications of selection for anthelmintic resistance in parasitic nematodes. Parasitology Today 11, 148-150.
22. Siles-Lucas, M., Merli, M. & Gottstein, B. (2008) 14-3-3 proteins in Echinococcus: their role and potential as protective antigens. Experimental Parasitology 119, 516-523. (Pubitemid 351952239)
23. Sullivan, K.F. (1988) Structure and utilization of tubulin isotypes. Annual Review of Cell Biology 4, 687-716. (Pubitemid 19139269)
24. Tamura, K., Dudley, J., Nei, M. & Kumar, S. (2007) MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0. Molecular Biology and Evolution 24, 1596-1599. (Pubitemid 47236692)
25. Thomas, J.H., Neff, N.F. & Botstein, D. (1995) Isolation and characterization of mutations in the betatubulin gene of Saccharomyces cerevisiae. Genetics 111, 715-734.
26. Towbin, H., Staehelin, T. & Gordon, J. (1979) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proceedings of the National Academy of Science, USA 76, 4350-4354. (Pubitemid 9256559)
27. van Hemert, M.J., Steensma, H.Y. & van Heusden, G.P. (2001) 14-3-3 proteins: key regulators of cell division, signalling and apoptosis. Bioessays 23, 936-946. (Pubitemid 32972693)
28. van Heusden, G. & Steensma, H.Y. (2006) Yeast 14-3-3 proteins. Yeast 23, 159-171.
29. Xie, T., Ho, S.L. & Ma, O.C. (1997) High resolution single strand conformation polymorphism analysis using formamide and ethidium bromide staining. Molecular Pathology 50, 276-278. (Pubitemid 27475782)