Possible participation of nitric oxide/cyclic guanosine monophosphate/protein kinase C/ATP-sensitive K + channels pathway in the systemic antinociception of flavokawin B

Basic and Clinical Pharmacology and Toxicology

Volumn 108, Issue 6, 2011, Pages 400-405

  Mohamad, Azam Shah ^a   Akhtar, Muhammad Nadeem ^a   Khalivulla, Shaik Ibrahim ^a   Perimal, Enoch Kumar ^a   Khalid, Mohamed Hanief ^a   Ong, Hui Ming ^a   Zareen, Seema ^a   Akira, Ahmad ^a   Israf, Daud Ahmad ^a   Lajis, Nordin ^a   Sulaiman, Mohd Roslan ^a  

^a UNIVERSITY PUTRA MALAYSIA   (Malaysia)

Author keywords

[No Author keywords available]

Indexed keywords

ACETIC ACID; ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; ARGININE; CHALCONE DERIVATIVE; CYCLIC GMP; FLAVOKAWIN B; GLIBENCLAMIDE; METHYLENE BLUE; NITRIC OXIDE; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DRUG INHIBITION; DRUG MECHANISM; DRUG STRUCTURE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANALGESICS; ANIMALS; ARGININE; CYCLIC GMP; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; FLAVONOIDS; GLYBURIDE; HYPOGLYCEMIC AGENTS; MALE; METHYLENE BLUE; MICE; MICE, INBRED ICR; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PAIN; POTASSIUM CHANNELS; PROTEIN KINASE C; SIGNAL TRANSDUCTION;

MUS;

EID: 79955979409     PISSN: 17427835     EISSN: 17427843     Source Type: Journal    
DOI: 10.1111/j.1742-7843.2010.00670.x     Document Type: Article

References (37)

1. Correa R, Pereira MA, Buffon D, dos Santos L, Cechinell Filho V, Santos AR et al. Antinociceptive properties of chalcones. Structure-activity relationships. Arch Pharm (Weinheim) 2001;334:332-4.
2. Joseph CC, Magadula JJ, Nkunya MH. A novel antiplasmodial 3', 5'-diformylchalcone and other constituents of Friesodielsia obovata. Nat Prod Res 2007;21:1009-15.
3. Tsukiyama R, Katsura H, Tokuriki N, Kobayashi M. Antibacterial activity of licochalcone A against spore-forming bacteria. Antimicrob Agents Chemother 2002;46:1226-30.
4. Panda SS, Chowdary PV, Jayashree BS. Synthesis, antiinflammatory and antibacterial activity of novel indolyl-isoxazoles. Indian J Pharm Sci 2009;71:684-7.
5. Boumendjel A, Ronot X, Boutonnat J. Chalcones derivatives acting as cell cycle blockers: potential anti cancer drugs? Curr Drug Targets 2009;10:363-71.
6. Zhao LM, Jin HS, Sun LP, Piao HR, Quan ZS. Synthesis and evaluation of antiplatelet activity of trihydroxychalcone derivatives. Bioorg Med Chem Lett 2005;15:5027-9.
7. Rao YK, Fang SH, Tzeng YM. Synthesis and biological evaluation of 3', 4', 5'-trimethoxychalcone analogues as inhibitors of nitric oxide production and tumor cell proliferation. Bioorg Med Chem 2009;17:7909-14.
8. Kim JY, Park SJ, Yun KJ, Cho YW, Park HJ, Lee KT. Isoliquiritigenin isolated from the roots of Glycyrrhiza uralensis inhibits LPS-induced iNOS and COX-2 expression via the attenuation of NF-kappaB in RAW 264.7 macrophages. Eur J Pharmacol 2008;584:175-84.
9. Israf DA, Khaizurin TA, Syahida A, Lajis NH, Khozirah S. Cardamonin inhibits COX and iNOS expression via inhibition of p65NF-kappaB nuclear translocation and Ikappa-B phosphorylation in RAW 264.7 macrophage cells. Mol Immunol 2007;44:673-9.
10. Ahmad S, Israf DA, Lajis NH, Shaari K, Mohamed H, Wahab AA et al. Cardamonin, inhibits pro-inflammatory mediators in activated RAW 264.7 cells and whole blood. Eur J Pharmacol 2006;538:188-94.
11. Habsah M, Lajis NH, Ali AM, Sukari MA, Hin YY, Kikuzaki H et al. The Antioxidative components from Alpinia nutans. Pharm Biol 2003;41:7-9.
12. Mohamad AS, Akhtar MN, Zakaria ZA, Perimal EK, Khalid S, Mohd PA et al. Antinociceptive activity of a synthetic chalcone, flavokawin B on chemical and thermal models of nociception in mice. Eur J Pharmacol 2010;647:103-9.
13. Abacioglu N, Tunctan B, Akbulut E, Cakici I. Participation of the components of L-arginine/nitric oxide/cGMP cascade by chemically-induced abdominal constriction in the mouse. Life Sci 2000;67:1127-37.
14. Durate ID, Lorenzetti BB, Ferreira SH. Peripheral analgesia and activation of the nitric oxide-cyclic GMP pathway. Eur J Pharmacol 1990;186:289-93.
15. Jain NK, Patil CS, Singh A, Kulkarni SK. Sildenafil-induced peripheral analgesia and activation of the nitric oxide-cyclic GMP pathway. Brain Res 2001;909:170-8.
16. Jesse CR, Savegnago L, Nogueira CW. Role of nitric oxide/cyclic GMP/K(+) channel pathways in the antinociceptive effect caused by 2, 3-bis(mesitylseleno)propenol. Life Sci 2007;81:1694-702.
17. Syahida A, Israf DA, Lajis NH, Khozirah S, Habsah M, Jasril et al. Effect of compounds isolated from natural products on IFN-γ/LPS-induced nitric oxide production in RAW 264.7 macrophages. Pharm Biol 2006;445:50-9.
18. Lin CT, Senthil Kumar KJ, Tseng YH, Wang ZJ, Pan MY, Xiao JH et al. Anti-inflammatory activity of Flavokawain B from Alpinia pricei Hayata. J Agric Food Chem 2009;57:6060-5.
19. Sulaiman MR, Somchit MN, Israf DA, Ahmad Z, Moin S. Antinociceptive effect of Melastoma malabathricum ethanolic extract in mice. Fitoterapia 2004;75:667-72.
20. Santos ARS, Gadotti VM, Oliveira GL, Tibola D, Paszcuk AF, Neto A et al. Mechanisms involved in the antinociception caused by agmatine in mice. Neuropharmacology 2005;48:1021-34.
21. Ferreira J, Triches KM, Medeiros R, Cabrini DA, Mori MA, Pesquero JB et al. The role of kinin B1 receptors in the nociception produced by peripheral protein kinase C activation in mice. Neuropharmacology 2008;54:597-604.
22. Savegnago L, Pinto LG, Jesse CR, Alves D, Rocha JB, Nogueira CW et al. Antinociceptive properties of diphenyl diselenide: evidences for the mechanism of action. Eur J Pharmacol 2007;555:129-38.
23. Julius D, Basbaum AI. Molecular mechanisms of nociception. Nature 2001;413:203-10.
24. Deraedt R, Jouquey S, Delevallee F, Flahaut M. Release of prostaglandins E and F in an algogenic reaction and its inhibition. Eur J Pharmacol 1980;61:17-24.
25. Rivot JP, Montagne-Clavel J, Besson JM. Subcutaneous formalin and intraplantar carrageenan increase nitric oxide release as measured by in vivo voltammetry in the spinal cord. Eur J Pain 2002;6:25-34.
26. Jesse CR, Rocha JB, Nogueira CW, Savegnago L. Further analysis of the antinociceptive action caused by p-methoxyl-diphenyl diselenide in mice. Pharmacol Biochem Behav 2009;91:573-80.
27. Soares de Moura R, Rios AAS, Santos EJA, Amorim Nascimento AB, de Castro Resende Â, Lemos Neto M et al. Role of the NO-cGMP pathway in the systemic antinociceptive effect of clonidine in rats and mice. Pharmacol Biochem Behav 2004;78:247-53.
28. Pyne NJ, Arshavsky V, Lochhead A. cGMP signal termination. Biochem Soc Trans 1996;24:1019-22.
29. Maruna P, Masek Z, Schreiber V. Methylene blue inhibition of oestradiol-induced increase of ceruloplasmin serum levels in rats. Physiol Res 1994;43:219-21.
30. Holthusen H. Involvement of the NO/cyclic GMP pathway in bradykinin-evoked pain from veins in humans. Pain 1997;69:87-92.
31. Souza AL, Moreira FA, Almeida KR, Bertollo CM, Costa KA, Coelho MM. In vivo evidence for a role of protein kinase C in peripheral nociceptive processing. Br J Pharmacol 2002;135:239-47.
32. Tsuchiya M, Sakakibara A, Yamamoto M. A tachykinin NK1 receptor antagonist attenuates the 4 beta-phorbol-12-myristate-13-acetate-induced nociceptive behaviour in the rat. Eur J Pharmacol 2005;507:29-34.
33. Hucho T, Levine JD. Signaling pathways in sensitization: toward a nociceptor cell biology. Neuron 2007;55:365-76.
34. Mizumura K, Koda H, Kumazawa T. Possible contribution of protein kinase C in the effects of histamine on the visceral nociceptor activities in vitro. Neurosci Res 2000;37:183-90.
35. Ferreira J, Triches KM, Medeiros R, Calixto JB. Mechanisms involved in the nociception produced by peripheral protein kinase c activation in mice. Pain 2005;117:171-81.
36. Lazaro-Ibanez GG, Torres-Lopez JE, Granados-Soto V. Participation of the nitric oxide-cyclic GMP-ATP-sensitive K(+) channel pathway in the antinociceptive action of ketorolac. Eur J Pharmacol 2001;426:39-44.
37. + channels pathway by gabapentin on the formalin test. Pharmacol Biochem Behav 2006;83:420-7.