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Volumn 47, Issue 2, 2011, Pages 79-92

Fluorophore assisted light inactivation (FALI) of recombinant 5-HT3A receptor constitutive internalization and function

Author keywords

5 Hydroxytryptamine type 3 (5 HT3) receptors; Constitutive internalization; Electrophysiology; Fluorophore assisted light inactivation

Indexed keywords

ALPHA BUNGAROTOXIN; FLUORINE DERIVATIVE; OXYGEN RADICAL; PROTEIN TAG; REACTIVE OXYGEN METABOLITE; RECEPTOR SUBUNIT; RECOMBINANT RECEPTOR; SEROTONIN 3A RECEPTOR;

EID: 79955976725     PISSN: 10447431     EISSN: 10959327     Source Type: Journal    
DOI: 10.1016/j.mcn.2011.02.007     Document Type: Article
Times cited : (7)

References (44)
  • 1
    • 0036203661 scopus 로고    scopus 로고
    • Fluorophore-assisted light inactivation: a high-throughput tool for direct target validation of proteins
    • Beck S., Sakurai T., Eustace B.K., Beste G., Schier R., Rudert F., Jay D.G. Fluorophore-assisted light inactivation: a high-throughput tool for direct target validation of proteins. Proteomics 2002, 2:247-255.
    • (2002) Proteomics , vol.2 , pp. 247-255
    • Beck, S.1    Sakurai, T.2    Eustace, B.K.3    Beste, G.4    Schier, R.5    Rudert, F.6    Jay, D.G.7
  • 4
    • 0037564169 scopus 로고    scopus 로고
    • Singlet oxygen-mediated damage to proteins and its consequences
    • Davies M.J. Singlet oxygen-mediated damage to proteins and its consequences. Biochem. Biophys. Res. Commun. 2003, 305:761-770.
    • (2003) Biochem. Biophys. Res. Commun. , vol.305 , pp. 761-770
    • Davies, M.J.1
  • 5
    • 0028988761 scopus 로고
    • The role of 5-HT3 receptors in drug dependence
    • Grant K.A. The role of 5-HT3 receptors in drug dependence. Drug Alcohol Depend. 1995, 38:155-171.
    • (1995) Drug Alcohol Depend. , vol.38 , pp. 155-171
    • Grant, K.A.1
  • 6
    • 0034513772 scopus 로고    scopus 로고
    • Green fluorescent protein photobleaching: a model for protein damage by endogenous and exogenous singlet oxygen
    • Greenbaum L., Rothmann C., Lavie R., Malik Z. Green fluorescent protein photobleaching: a model for protein damage by endogenous and exogenous singlet oxygen. Biol. Chem. 2000, 381:1251-1258.
    • (2000) Biol. Chem. , vol.381 , pp. 1251-1258
    • Greenbaum, L.1    Rothmann, C.2    Lavie, R.3    Malik, Z.4
  • 7
    • 33749345272 scopus 로고    scopus 로고
    • Fluorophore-assisted light inactivation produces both targeted and collateral effects on N-type calcium channel modulation in rat sympathetic neurons
    • Guo J., Chen H., Puhl H.L., Ikeda S.R. Fluorophore-assisted light inactivation produces both targeted and collateral effects on N-type calcium channel modulation in rat sympathetic neurons. J. Physiol. 2006, 576:477-492.
    • (2006) J. Physiol. , vol.576 , pp. 477-492
    • Guo, J.1    Chen, H.2    Puhl, H.L.3    Ikeda, S.R.4
  • 8
    • 0037929806 scopus 로고    scopus 로고
    • Constitutive GABAA receptor endocytosis is dynamin-mediated and dependent on a dileucine AP2 adaptin-binding motif within the beta 2 subunit of the receptor
    • Herring D., Huang R., Singh M., Robinson L.C., Dillon G.H., Leidenheimer N.J. Constitutive GABAA receptor endocytosis is dynamin-mediated and dependent on a dileucine AP2 adaptin-binding motif within the beta 2 subunit of the receptor. J. Biol. Chem. 2003, 278:24046-24052.
    • (2003) J. Biol. Chem. , vol.278 , pp. 24046-24052
    • Herring, D.1    Huang, R.2    Singh, M.3    Robinson, L.C.4    Dillon, G.H.5    Leidenheimer, N.J.6
  • 9
    • 44849134443 scopus 로고    scopus 로고
    • Chemotherapy-induced nausea and vomiting
    • Hesketh P.J. Chemotherapy-induced nausea and vomiting. N. Engl. J. Med. 2008, 358:2482-2494.
    • (2008) N. Engl. J. Med. , vol.358 , pp. 2482-2494
    • Hesketh, P.J.1
  • 10
    • 0027251777 scopus 로고
    • Specific decreases in ethanol - but not water-reinforced responding produced by the 5-HT3 antagonist ICS 205-930
    • Hodge C.W., Samson H.H., Lewis R.S., Erickson H.L. Specific decreases in ethanol - but not water-reinforced responding produced by the 5-HT3 antagonist ICS 205-930. Alcohol 1993, 10:191-196.
    • (1993) Alcohol , vol.10 , pp. 191-196
    • Hodge, C.W.1    Samson, H.H.2    Lewis, R.S.3    Erickson, H.L.4
  • 11
    • 17444404900 scopus 로고    scopus 로고
    • Toward understanding the mechanism of chromophore-assisted laser inactivation-evidence for the primary photochemical steps
    • Horstkotte E., Schroder T., Niewohner J., Thiel E., Jay D.G., Henning S.W. Toward understanding the mechanism of chromophore-assisted laser inactivation-evidence for the primary photochemical steps. Photochem. Photobiol. 2005, 81:358-366.
    • (2005) Photochem. Photobiol. , vol.81 , pp. 358-366
    • Horstkotte, E.1    Schroder, T.2    Niewohner, J.3    Thiel, E.4    Jay, D.G.5    Henning, S.W.6
  • 12
    • 49849101836 scopus 로고    scopus 로고
    • Chromophore-assisted laser inactivation in cell biology
    • Jacobson K., Rajfur Z., Vitriol E., Hahn K. Chromophore-assisted laser inactivation in cell biology. Trends Cell Biol. 2008, 18:443-450.
    • (2008) Trends Cell Biol. , vol.18 , pp. 443-450
    • Jacobson, K.1    Rajfur, Z.2    Vitriol, E.3    Hahn, K.4
  • 13
    • 0000601644 scopus 로고
    • Selective destruction of protein function by chromophore-assisted laser inactivation
    • Jay D.G. Selective destruction of protein function by chromophore-assisted laser inactivation. Proc. Natl Acad. Sci. USA 1988, 85:5454-5458.
    • (1988) Proc. Natl Acad. Sci. USA , vol.85 , pp. 5454-5458
    • Jay, D.G.1
  • 15
    • 51649098809 scopus 로고    scopus 로고
    • Inactivation of clathrin heavy chain inhibits synaptic recycling but allows bulk membrane uptake
    • Kasprowicz J., Kuenen S., Miskiewicz K., Habets R.L., Smitz L., Verstreken P. Inactivation of clathrin heavy chain inhibits synaptic recycling but allows bulk membrane uptake. J. Cell Biol. 2008, 182:1007-1016.
    • (2008) J. Cell Biol. , vol.182 , pp. 1007-1016
    • Kasprowicz, J.1    Kuenen, S.2    Miskiewicz, K.3    Habets, R.L.4    Smitz, L.5    Verstreken, P.6
  • 16
    • 0034310719 scopus 로고    scopus 로고
    • Constitutive endocytosis of GABAA receptors by an association with the adaptin AP2 complex modulates inhibitory synaptic currents in hippocampal neurons
    • Kittler J.T., Delmas P., Jovanovic J.N., Brown D.A., Smart T.G., Moss S.J. Constitutive endocytosis of GABAA receptors by an association with the adaptin AP2 complex modulates inhibitory synaptic currents in hippocampal neurons. J. Neurosci. 2000, 20:7972-7977.
    • (2000) J. Neurosci. , vol.20 , pp. 7972-7977
    • Kittler, J.T.1    Delmas, P.2    Jovanovic, J.N.3    Brown, D.A.4    Smart, T.G.5    Moss, S.J.6
  • 17
    • 37149032225 scopus 로고    scopus 로고
    • A general system for evaluating the efficiency of chromophore-assisted light inactivation (CALI) of proteins reveals Ru(II) tris-bipyridyl as an unusually efficient "warhead"
    • Lee J., Yu P., Xiao X., Kodadek T. A general system for evaluating the efficiency of chromophore-assisted light inactivation (CALI) of proteins reveals Ru(II) tris-bipyridyl as an unusually efficient "warhead". Mol. Biosyst. 2008, 4:59-65.
    • (2008) Mol. Biosyst. , vol.4 , pp. 59-65
    • Lee, J.1    Yu, P.2    Xiao, X.3    Kodadek, T.4
  • 18
    • 0026589934 scopus 로고
    • Spatial specificity of chromophore assisted laser inactivation of protein function
    • Linden K.G., Liao J.C., Jay D.G. Spatial specificity of chromophore assisted laser inactivation of protein function. Biophys. J. 1992, 61:956-962.
    • (1992) Biophys. J. , vol.61 , pp. 956-962
    • Linden, K.G.1    Liao, J.C.2    Jay, D.G.3
  • 19
    • 0037028010 scopus 로고    scopus 로고
    • Transgenically encoded protein photoinactivation (FlAsH-FALI): acute inactivation of synaptotagmin I
    • Marek K.W., Davis G.W. Transgenically encoded protein photoinactivation (FlAsH-FALI): acute inactivation of synaptotagmin I. Neuron 2002, 36:805-813.
    • (2002) Neuron , vol.36 , pp. 805-813
    • Marek, K.W.1    Davis, G.W.2
  • 20
    • 0025997336 scopus 로고
    • Primary structure and functional expression of the 5HT3 receptor, a serotonin-gated ion channel
    • Maricq A.V., Peterson A.S., Brake A.J., Myers R.M., Julius D. Primary structure and functional expression of the 5HT3 receptor, a serotonin-gated ion channel. Science 1991, 254:432-437.
    • (1991) Science , vol.254 , pp. 432-437
    • Maricq, A.V.1    Peterson, A.S.2    Brake, A.J.3    Myers, R.M.4    Julius, D.5
  • 21
    • 27744503306 scopus 로고    scopus 로고
    • Peptide tags for labeling membrane proteins in live cells with multiple fluorophores
    • McCann C.M., Bareyre F.M., Lichtman J.W., Sanes J.R. Peptide tags for labeling membrane proteins in live cells with multiple fluorophores. Biotechniques 2005, 38:945-952.
    • (2005) Biotechniques , vol.38 , pp. 945-952
    • McCann, C.M.1    Bareyre, F.M.2    Lichtman, J.W.3    Sanes, J.R.4
  • 22
    • 0033780316 scopus 로고    scopus 로고
    • Effects of MDL 72222, a serotonin3 antagonist, on operant responding for ethanol by alcohol-preferring P rats
    • McKinzie D.L., McBride W.J., Murphy J.M., Lumeng L., Li T.K. Effects of MDL 72222, a serotonin3 antagonist, on operant responding for ethanol by alcohol-preferring P rats. Alcohol. Clin. Exp. Res. 2000, 24:1500-1504.
    • (2000) Alcohol. Clin. Exp. Res. , vol.24 , pp. 1500-1504
    • McKinzie, D.L.1    McBride, W.J.2    Murphy, J.M.3    Lumeng, L.4    Li, T.K.5
  • 25
    • 0037835606 scopus 로고    scopus 로고
    • Cloning, physical mapping and expression analysis of the human 5-HT3 serotonin receptor-like genes HTR3C, HTR3D and HTR3E
    • Niesler B., Frank B., Kapeller J., Rappold G.A. Cloning, physical mapping and expression analysis of the human 5-HT3 serotonin receptor-like genes HTR3C, HTR3D and HTR3E. Gene 2003, 310:101-111.
    • (2003) Gene , vol.310 , pp. 101-111
    • Niesler, B.1    Frank, B.2    Kapeller, J.3    Rappold, G.A.4
  • 27
    • 0033994306 scopus 로고    scopus 로고
    • 5-HT(3) receptor antagonists and anxiety; a preclinical and clinical review
    • Olivier B., van Wijngaarden I., Soudijn W. 5-HT(3) receptor antagonists and anxiety; a preclinical and clinical review. Eur. Neuropsychopharmacol. 2000, 10:77-95.
    • (2000) Eur. Neuropsychopharmacol. , vol.10 , pp. 77-95
    • Olivier, B.1    van Wijngaarden, I.2    Soudijn, W.3
  • 28
    • 0024472716 scopus 로고
    • Electrophysiology of 5-HT3 receptors in neuronal cell lines
    • Peters J.A., Lambert J.J. Electrophysiology of 5-HT3 receptors in neuronal cell lines. Trends Pharmacol. Sci. 1989, 10:172-175.
    • (1989) Trends Pharmacol. Sci. , vol.10 , pp. 172-175
    • Peters, J.A.1    Lambert, J.J.2
  • 29
    • 34249025106 scopus 로고    scopus 로고
    • Chromophore-assisted light inactivation of pKi-67 leads to inhibition of ribosomal RNA synthesis
    • Rahmanzadeh R., Huttmann G., Gerdes J., Scholzen T. Chromophore-assisted light inactivation of pKi-67 leads to inhibition of ribosomal RNA synthesis. Cell Prolif. 2007, 40:422-430.
    • (2007) Cell Prolif. , vol.40 , pp. 422-430
    • Rahmanzadeh, R.1    Huttmann, G.2    Gerdes, J.3    Scholzen, T.4
  • 30
    • 0036228954 scopus 로고    scopus 로고
    • Dissecting the link between stress fibres and focal adhesions by CALI with EGFP fusion proteins
    • Rajfur Z., Roy P., Otey C., Romer L., Jacobson K. Dissecting the link between stress fibres and focal adhesions by CALI with EGFP fusion proteins. Nat. Cell Biol. 2002, 4:286-293.
    • (2002) Nat. Cell Biol. , vol.4 , pp. 286-293
    • Rajfur, Z.1    Roy, P.2    Otey, C.3    Romer, L.4    Jacobson, K.5
  • 31
    • 10944248345 scopus 로고    scopus 로고
    • A novel pharmatope tag inserted into the beta4 subunit confers allosteric modulation to neuronal nicotinic receptors
    • Sanders T., Hawrot E. A novel pharmatope tag inserted into the beta4 subunit confers allosteric modulation to neuronal nicotinic receptors. J. Biol. Chem. 2004, 279:51460-51465.
    • (2004) J. Biol. Chem. , vol.279 , pp. 51460-51465
    • Sanders, T.1    Hawrot, E.2
  • 33
    • 33750690583 scopus 로고    scopus 로고
    • Photosensitized generation of singlet oxygen
    • Schmidt R. Photosensitized generation of singlet oxygen. Photochem. Photobiol. 2006, 82:1161-1177.
    • (2006) Photochem. Photobiol. , vol.82 , pp. 1161-1177
    • Schmidt, R.1
  • 34
    • 10344223003 scopus 로고    scopus 로고
    • Imaging of receptor trafficking by using alpha-bungarotoxin-binding-site-tagged receptors
    • Sekine-Aizawa Y., Huganir R.L. Imaging of receptor trafficking by using alpha-bungarotoxin-binding-site-tagged receptors. Proc. Natl Acad. Sci. USA 2004, 101:17114-17119.
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 17114-17119
    • Sekine-Aizawa, Y.1    Huganir, R.L.2
  • 36
    • 23644433309 scopus 로고    scopus 로고
    • Multiphoton excitation-evoked chromophore-assisted laser inactivation using green fluorescent protein
    • Tanabe T., Oyamada M., Fujita K., Dai P., Tanaka H., Takamatsu T. Multiphoton excitation-evoked chromophore-assisted laser inactivation using green fluorescent protein. Nat. Methods. 2005, 2:503-505.
    • (2005) Nat. Methods. , vol.2 , pp. 503-505
    • Tanabe, T.1    Oyamada, M.2    Fujita, K.3    Dai, P.4    Tanaka, H.5    Takamatsu, T.6
  • 37
    • 0027409041 scopus 로고
    • Nervous system distribution of the serotonin 5-HT3 receptor mRNA
    • Tecott L.H., Maricq A.V., Julius D. Nervous system distribution of the serotonin 5-HT3 receptor mRNA. Proc. Natl Acad. Sci. USA 1993, 90:1430-1434.
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 1430-1434
    • Tecott, L.H.1    Maricq, A.V.2    Julius, D.3
  • 39
    • 34249847071 scopus 로고    scopus 로고
    • Enhanced EGFP-chromophore-assisted laser inactivation using deficient cells rescued with functional EGFP-fusion proteins
    • Vitriol E.A., Uetrecht A.C., Shen F., Jacobson K., Bear J.E. Enhanced EGFP-chromophore-assisted laser inactivation using deficient cells rescued with functional EGFP-fusion proteins. Proc. Natl Acad. Sci. USA 2007, 104:6702-6707.
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , pp. 6702-6707
    • Vitriol, E.A.1    Uetrecht, A.C.2    Shen, F.3    Jacobson, K.4    Bear, J.E.5
  • 41
    • 58049206253 scopus 로고    scopus 로고
    • Tracking cell surface GABAB receptors using an alpha-bungarotoxin tag
    • Wilkins M.E., Li X., Smart T.G. Tracking cell surface GABAB receptors using an alpha-bungarotoxin tag. J. Biol. Chem. 2008, 283:34745-34752.
    • (2008) J. Biol. Chem. , vol.283 , pp. 34745-34752
    • Wilkins, M.E.1    Li, X.2    Smart, T.G.3
  • 42
    • 77949522347 scopus 로고    scopus 로고
    • A conserved cysteine residue in the third transmembrane domain is essential for homomeric 5-HT3 receptor function
    • Wu D.F., Othman N.A., Sharp D., Mahendra A., Deeb T.Z., Hales T.G. A conserved cysteine residue in the third transmembrane domain is essential for homomeric 5-HT3 receptor function. J. Physiol. 2009, 588:603-616.
    • (2009) J. Physiol. , vol.588 , pp. 603-616
    • Wu, D.F.1    Othman, N.A.2    Sharp, D.3    Mahendra, A.4    Deeb, T.Z.5    Hales, T.G.6
  • 43
    • 38549146611 scopus 로고    scopus 로고
    • Anandamide inhibition of 5-HT3A receptors varies with receptor density and desensitization
    • Xiong W., Hosoi M., Koo B.N., Zhang L. Anandamide inhibition of 5-HT3A receptors varies with receptor density and desensitization. Mol. Pharmacol. 2008, 73:314-322.
    • (2008) Mol. Pharmacol. , vol.73 , pp. 314-322
    • Xiong, W.1    Hosoi, M.2    Koo, B.N.3    Zhang, L.4
  • 44
    • 33645921635 scopus 로고    scopus 로고
    • Fluorophore-assisted light inactivation of calmodulin involves singlet-oxygen mediated cross-linking and methionine oxidation
    • Yan P., Xiong Y., Chen B., Negash S., Squier T.C., Mayer M.U. Fluorophore-assisted light inactivation of calmodulin involves singlet-oxygen mediated cross-linking and methionine oxidation. Biochemistry 2006, 45:4736-4748.
    • (2006) Biochemistry , vol.45 , pp. 4736-4748
    • Yan, P.1    Xiong, Y.2    Chen, B.3    Negash, S.4    Squier, T.C.5    Mayer, M.U.6


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