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Volumn 117, Issue 17, 2011, Pages 4580-4589

Down-regulation of stathmin expression is required for megakaryocyte maturation and platelet production

Author keywords

[No Author keywords available]

Indexed keywords

LENTIVIRUS VECTOR; STATHMIN; THROMBIN RECEPTOR;

EID: 79955968327     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2010-09-305540     Document Type: Article
Times cited : (25)

References (48)
  • 1
    • 67849088732 scopus 로고    scopus 로고
    • Regulation of megakaryocyte maturation and platelet formation
    • Bluteau D, Lordier L, Di Stefano A, et al. Regulation of megakaryocyte maturation and platelet formation. J Thromb Haemost. 2009;7(suppl 1):227-234.
    • (2009) J Thromb Haemost , vol.7 , Issue.SUPPL. 1 , pp. 227-234
    • Bluteau, D.1    Lordier, L.2    Di Stefano, A.3
  • 2
    • 34648833029 scopus 로고    scopus 로고
    • Delivering new insight into the biology of megakaryopoiesis and thrombopoiesis
    • DOI 10.1097/MOH.0b013e3282bad151, PII 0006275220070900000002
    • Battinelli EM, Hartwig JH, Italiano JE Jr. Delivering new insight into the biology of megakaryopoiesis and thrombopoiesis. Curr Opin Hematol. 2007;14(5):419-426. (Pubitemid 47457630)
    • (2007) Current Opinion in Hematology , vol.14 , Issue.5 , pp. 419-426
    • Battinelli, E.M.1    Hartwig, J.H.2    Italiano Jr., J.E.3
  • 3
    • 0030727534 scopus 로고    scopus 로고
    • Thrombopoietin-induced polyploidization of bone marrow megakaryocytes is due to a unique regulatory mechanism in late mitosis
    • DOI 10.1083/jcb.139.2.449
    • Nagata Y, Muro Y, Todokoro K. Thrombopoietin-induced polyploidization of bone marrow megakaryocytes is due to a unique regulatory mechanism in late mitosis. J Cell Biol. 1997;139(2):449-457. (Pubitemid 27459316)
    • (1997) Journal of Cell Biology , vol.139 , Issue.2 , pp. 449-457
    • Nagata, Y.1    Muro, Y.2    Todokoro, K.3
  • 5
    • 54049128933 scopus 로고    scopus 로고
    • Megakaryocyte endomitosis is a failure of late cytokinesis related to defects in the contractile ring and Rho/Rock signaling
    • Lordier L, Jalil A, Aurade F, et al. Megakaryocyte endomitosis is a failure of late cytokinesis related to defects in the contractile ring and Rho/Rock signaling. Blood. 2008;112(8):3164-3174.
    • (2008) Blood , vol.112 , Issue.8 , pp. 3164-3174
    • Lordier, L.1    Jalil, A.2    Aurade, F.3
  • 6
    • 0035871861 scopus 로고    scopus 로고
    • Asymmetrical segregation of chromosomes with a normal metaphase/anaphase checkpoint in polyploid megakaryocytes
    • DOI 10.1182/blood.V97.8.2238
    • Roy L, Coullin P, Vitrat N, et al. Asymmetrical segregation of chromosomes with a normal metaphase/anaphase checkpoint in polyploid megakaryocytes. Blood. 2001;97(8):2238-2247. (Pubitemid 32291468)
    • (2001) Blood , vol.97 , Issue.8 , pp. 2238-2247
    • Roy, L.1    Coullin, P.2    Vitrat, N.3    Hellio, R.4    Debili, N.5    Weinstein, J.6    Bernheim, A.7    Vainchenker, W.8
  • 8
    • 0036468982 scopus 로고    scopus 로고
    • The oncoprotein 18/stathmin family of microtubule destabilizers
    • DOI 10.1016/S0955-0674(01)00289-7
    • Cassimeris L. The oncoprotein 18/stathmin family of microtubule destabilizers. Curr Opin Cell Biol. 2002;14(1):18-24. (Pubitemid 34131652)
    • (2002) Current Opinion in Cell Biology , vol.14 , Issue.1 , pp. 18-24
    • Cassimeris, L.1
  • 10
    • 0031745447 scopus 로고    scopus 로고
    • The stathmin phosphoprotein family: Intracellular localization and effects on the microtubule network
    • Gavet O, Ozon S, Manceau V, Lawler S, Curmi P, Sobel A. The stathmin phosphoprotein family: intracellular localization and effects on the microtubule network. J Cell Sci. 1998;111(22):3333-3346. (Pubitemid 28563036)
    • (1998) Journal of Cell Science , vol.111 , Issue.22 , pp. 3333-3346
    • Gavet, O.1    Ozon, S.2    Manceau, V.3    Lawler, S.4    Curmi, P.5    Sobel, A.6
  • 11
    • 0035524266 scopus 로고    scopus 로고
    • Oncoprotein 18 levels and phosphorylation mediate megakaryocyte polyploidization in human erythroleukemia cells
    • Chang C, Hora N, Huberman N, Hinderer R, KuKuruga M, Hanash S. Oncoprotein 18 levels and phosphorylation mediate megakaryocyte polyploidization in human erythroleukemia cells. Proteomics. 2001;1:1415-1423. (Pubitemid 33587897)
    • (2001) Proteomics , vol.1 , Issue.11 , pp. 1415-1423
    • Chang, C.L.1    Hora, N.2    Huberman, N.3    Hinderer, R.4    KuKuruga, M.5    Hanash, S.M.6
  • 12
    • 0038577270 scopus 로고    scopus 로고
    • Stathmin expression and megakaryocyte differentiation: A potential role in polyploidy
    • DOI 10.1016/S0301-472X(03)00043-2
    • Iancu-Rubin C, French DL, Atweh GF. Stathmin expression and megakaryocyte differentiation: a potential role in polyploidy. Exp Hematol. 2003;31(5):389-397. (Pubitemid 36579364)
    • (2003) Experimental Hematology , vol.31 , Issue.5 , pp. 389-397
    • Rubin, C.I.1    French, D.L.2    Atweh, G.F.3
  • 13
    • 29244451434 scopus 로고    scopus 로고
    • Stathmin prevents the transition from a normal to an endomitotic cell cycle during megakaryocytic differentiation
    • Iancu-Rubin C, Nasrallah CA, Atweh GF. Stathmin prevents the transition from a normal to an endomitotic cell cycle during megakaryocytic differentiation. Cell Cycle. 2005;4(12):1774-1782. (Pubitemid 41827324)
    • (2005) Cell Cycle , vol.4 , Issue.12 , pp. 1774-1782
    • Iancu-Rubin, C.1    Nasrallah, C.A.2    Atweh, G.F.3
  • 14
    • 0035988781 scopus 로고    scopus 로고
    • Recombinant feline immunodeficiency virus vectors: Preparation and use
    • Curran MA, Nolan GP. Recombinant feline immunodeficiency virus vectors: preparation and use. Methods Mol Med. 2002;69:335-350.
    • (2002) Methods Mol Med , vol.69 , pp. 335-350
    • Curran, M.A.1    Nolan, G.P.2
  • 18
    • 0033642822 scopus 로고    scopus 로고
    • Efficient transduction of nondividing cells by optimized feline immunodeficiency virus vectors
    • Curran MA, Kaiser SM, Achacoso PL, Nolan GP. Efficient transduction of nondividing cells by optimized feline immunodeficiency virus vectors. Mol Ther. 2000;1(1):31-38.
    • (2000) Mol Ther , vol.1 , Issue.1 , pp. 31-38
    • Curran, M.A.1    Kaiser, S.M.2    Achacoso, P.L.3    Nolan, G.P.4
  • 19
    • 0030750560 scopus 로고    scopus 로고
    • Control of microtubule dynamics by oncoprotein 18: Dissection of the regulatory role of multisite phosphorylation during mitosis
    • Larsson N, Marklund U, Gradin HM, Brattsand G, Gullberg M. Control of microtubule dynamics by oncoprotein 18: dissection of the regulatory role of multisite phosphorylation during mitosis. Mol Cell Biol. 1997;17(9):5530-5539. (Pubitemid 27357649)
    • (1997) Molecular and Cellular Biology , vol.17 , Issue.9 , pp. 5530-5539
    • Larsson, N.1    Marklund, U.2    Gradin, H.M.3    Brattsand, G.4    Gullberg, M.5
  • 20
    • 0032472211 scopus 로고    scopus 로고
    • Stathmin overexpression in 293 cells affects signal transduction and cell growth
    • DOI 10.1016/S0014-5793(97)01519-6, PII S0014579397015196
    • Lawler S, Gavet O, Rich T, Sobel A. Stathmin overexpression in 293 cells affects signal transduction and cell growth. FEBS Lett. 1998;421(1):55-60. (Pubitemid 28068818)
    • (1998) FEBS Letters , vol.421 , Issue.1 , pp. 55-60
    • Lawler, S.1    Gavet, O.2    Rich, T.3    Sobel, A.4
  • 21
    • 16544382801 scopus 로고    scopus 로고
    • The role of stathmin in the regulation of the cell cycle
    • DOI 10.1002/jcb.20187
    • Iancu-Rubin C, Atweh GF. The role of stathmin in the regulation of the cell cycle. J Cell Biochem. 2004;93(2):242-250. (Pubitemid 44264202)
    • (2004) Journal of Cellular Biochemistry , vol.93 , Issue.2 , pp. 242-250
    • Rubin, C.I.1    Atweh, G.F.2
  • 22
    • 34250727187 scopus 로고    scopus 로고
    • From hematopoietic stem cells to platelets
    • DOI 10.1111/j.1538-7836.2007.02472.x, State of the Art 2007: XXI Congress of the International Society on Thrombosis and Haemostasis
    • Chang Y, Bluteau D, Debili N, Vainchenker W. From hematopoietic stem cells to platelets. J Thromb Haemost. 2007;5(suppl 1):318-327. (Pubitemid 46958849)
    • (2007) Journal of Thrombosis and Haemostasis , vol.5 , Issue.SUPPL. 1 , pp. 318-327
    • Chang, Y.1    Bluteau, D.2    Debili, N.3    Vainchenker, W.4
  • 24
    • 60849089339 scopus 로고    scopus 로고
    • Megakaryocyte-derived microparticles: Direct visualization and distinction from platelet-derived microparticles
    • Flaumenhaft R, Dilks JR, Richardson J, et al. Megakaryocyte-derived microparticles: direct visualization and distinction from platelet-derived microparticles. Blood. 2009;113(5):1112-1121.
    • (2009) Blood , vol.113 , Issue.5 , pp. 1112-1121
    • Flaumenhaft, R.1    Dilks, J.R.2    Richardson, J.3
  • 25
    • 0032055178 scopus 로고    scopus 로고
    • Multivesicular bodies are an intermediate stage in the formation of platelet α-granules
    • Heijnen HF, Debili N, Vainchencker W, Breton-Gorius J, Geuze HJ, Sixma JJ. Multivesicular bodies are an intermediate stage in the formation of platelet alpha-granules. Blood. 1998;91(7):2313-2325. (Pubitemid 28155504)
    • (1998) Blood , vol.91 , Issue.7 , pp. 2313-2325
    • Heijnen, H.F.G.1    Debili, N.2    Vainchencker, W.3    Breton-Gorius, J.4    Geuze, H.J.5    Sixma, J.J.6
  • 26
    • 0034659852 scopus 로고    scopus 로고
    • Megakaryocyte dense granule components are sorted in multivesicular bodies
    • Youssefian T, Cramer EM. Megakaryocyte dense granule components are sorted in multivesicular bodies. Blood. 2000;95(12):4004-4007. (Pubitemid 30412881)
    • (2000) Blood , vol.95 , Issue.12 , pp. 4004-4007
    • Youssefian, T.1    Cramer, E.M.2
  • 28
    • 0028171913 scopus 로고
    • The phenotype of a "Cdc2 kinase target site-deficient" mutant of oncoprotein 18 reveals a role of this protein in cell cycle control
    • Marklund U, Osterman O, Melander H, Bergh A, Gullberg M. The phenotype of a "Cdc2 kinase target site-deficient" mutant of oncoprotein 18 reveals a role of this protein in cell cycle control. J Biol Chem. 1994;269(48):30626-30635.
    • (1994) J Biol Chem , vol.269 , Issue.48 , pp. 30626-30635
    • Marklund, U.1    Osterman, O.2    Melander, H.3    Bergh, A.4    Gullberg, M.5
  • 29
    • 33846208700 scopus 로고    scopus 로고
    • Therapeutic interactions between stathmin inhibition and chemotherapeutic agents in prostate cancer
    • DOI 10.1158/1535-7163.MCT-06-0227
    • Mistry SJ, Atweh GF. Therapeutic interactions between stathmin inhibition and chemotherapeutic agents in prostate cancer. Mol Cancer Ther. 2006;5(12):3248-3257. (Pubitemid 46092068)
    • (2006) Molecular Cancer Therapeutics , vol.5 , Issue.12 , pp. 3248-3257
    • Mistry, S.J.1    Atweh, G.F.2
  • 30
    • 36849019596 scopus 로고    scopus 로고
    • Inhibiting proliferation and enhancing chemosensitivity to taxanes in osteosarcoma cells by RNA interference-mediated downregulation of stathmin expression
    • DOI 10.2119/2007-00046.Wang
    • Wang R, Dong K, Lin F, et al. Inhibiting proliferation and enhancing chemosensitivity to taxanes in osteosarcoma cells by RNA interference-mediated downregulation of stathmin expression. Mol Med. 2007;13(11):567-575. (Pubitemid 350228717)
    • (2007) Molecular Medicine , vol.13 , Issue.11-12 , pp. 567-575
    • Wang, R.1    Dong, K.2    Lin, F.3    Wang, X.4    Gao, P.5    Wei, S.-H.6    Cheng, S.-Y.7    Zhang, H.-Z.8
  • 31
    • 0027253551 scopus 로고
    • Quantitative analysis of the expression and regulation of an activation-regulated phosphoprotein (oncoprotein 18) in normal and neoplastic cells
    • Brattsand G, Roos G, Marklund U, et al. Quantitative analysis of the expression and regulation of an activation-regulated phosphoprotein (oncoprotein 18) in normal and neoplastic cells. Leukemia. 1993;7(4):569-579. (Pubitemid 23139861)
    • (1993) Leukemia , vol.7 , Issue.4 , pp. 569-579
    • Brattsand, G.1    Roos, G.2    Marklund, U.3    Ueda, H.4    Landberg, G.5    Nanberg, E.6    Sideras, P.7    Gullberg, M.8
  • 32
    • 33846921020 scopus 로고    scopus 로고
    • Expression analysis of primary mouse megakaryocyte differentiation and its application in identifying stage-specific molecular markers and a novel transcriptional target of NF-E2
    • DOI 10.1182/blood-2006-08-038901
    • Chen Z, Hu M, Shivdasani RA. Expression analysis of primary mouse megakaryocyte differentiation and its application in identifying stage-specific molecular markers and a novel transcriptional target of NF-E2. Blood. 2007;109(4):1451-1459. (Pubitemid 46239576)
    • (2007) Blood , vol.109 , Issue.4 , pp. 1451-1459
    • Chen, Z.1    Hu, M.2    Shivdasani, R.A.3
  • 34
    • 23044499360 scopus 로고    scopus 로고
    • Differential requirements for the activation domain and FOG-interaction surface of GATA-1 in megakaryocyte gene expression and development
    • DOI 10.1182/blood-2005-02-0551
    • Muntean AG, Crispino JD. Differential requirements for the activation domain and FOG-interaction surface of GATA-1 in megakaryocyte gene expression and development. Blood. 2005;106(4):1223-1231. (Pubitemid 41129583)
    • (2005) Blood , vol.106 , Issue.4 , pp. 1223-1231
    • Muntean, A.G.1    Crispino, J.D.2
  • 35
    • 1242271991 scopus 로고    scopus 로고
    • Regulation of Microtubule Destabilizing Activity of Op18/Stathmin Downstream of Rac1
    • DOI 10.1074/jbc.M307261200
    • Wittmann T, Bokoch GM, Waterman-Storer CM. Regulation of microtubule destabilizing activity of Op18/stathmin downstream of Rac1. J Biol Chem. 2004;279(7):6196-6203. (Pubitemid 38220653)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.7 , pp. 6196-6203
    • Wittmann, T.1    Bokoch, G.M.2    Waterman-Storer, C.M.3
  • 36
    • 0035910554 scopus 로고    scopus 로고
    • Rac/Cdc42 and p65PAK regulate the microtubule-destabilizing protein stathmin through phosphorylation at serine 16
    • DOI 10.1074/jbc.C000635200
    • Daub H, Gevaert K, Vandekerckhove J, Sobel A, Hall A. Rac/Cdc42 and p65PAK regulate the microtubule-destabilizing protein stathmin through phosphorylation at serine 16. J Biol Chem. 2001;276(3):1677-1680. (Pubitemid 32109635)
    • (2001) Journal of Biological Chemistry , vol.276 , Issue.3 , pp. 1677-1680
    • Daub, H.1    Gevaert, K.2    Vandekerckhove, J.3    Sobel, A.4    Hall, A.5
  • 37
    • 33645231284 scopus 로고    scopus 로고
    • Aurora B is required for mitotic chromatin-induced phosphorylation of Op18/Stathmin
    • Gadea BB, Ruderman JV. Aurora B is required for mitotic chromatin-induced phosphorylation of Op18/Stathmin. Proc Natl Acad Sci U S A. 2006;103(12):4493-4498.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , Issue.12 , pp. 4493-4498
    • Gadea, B.B.1    Ruderman, J.V.2
  • 38
    • 77957702911 scopus 로고    scopus 로고
    • Aurora B is dispensable for megakaryocyte polyploidization, but contributes to the endomitotic process
    • Lordier L, Chang Y, Jalil A, et al. Aurora B is dispensable for megakaryocyte polyploidization, but contributes to the endomitotic process. Blood. 2010;116(13):2345-2355.
    • (2010) Blood , vol.116 , Issue.13 , pp. 2345-2355
    • Lordier, L.1    Chang, Y.2    Jalil, A.3
  • 39
    • 0030916345 scopus 로고    scopus 로고
    • Polyploidization and functional maturation are two distinct processes during megakaryocytic differentiation: Involvement of cyclin-dependent kinase inhibitor p21 in polyploidization
    • Kikuchi J, Furukawa Y, Iwase S, et al. Polyploidization and functional maturation are two distinct processes during megakaryocytic differentiation: involvement of cyclin-dependent kinase inhibitor p21 in polyploidization. Blood. 1997;89(11):3980-3990. (Pubitemid 27220942)
    • (1997) Blood , vol.89 , Issue.11 , pp. 3980-3990
    • Kikuchi, J.1    Furukawa, Y.2    Lwase, S.3    Terui, Y.4    Nakamura, M.5    Kitagawa, S.6    Kitagawa, M.7    Komatsu, N.8    Miura, Y.9
  • 40
    • 0028961460 scopus 로고
    • Disruption of microtubules in vivo by vincristine induces large membrane complexes and other cytoplasmic abnormalities in megakaryocytes and platelets of normal rats like those in human and Wistar Furth rat hereditary macrothrombocytopenias
    • Stenberg PE, McDonald TP, Jackson CW. Disruption of microtubules in vivo by vincristine induces large membrane complexes and other cytoplasmic abnormalities in megakaryocytes and platelets of normal rats like those in human and Wistar Furth rat hereditary macrothrombocytopenias. J Cell Physiol. 1995;162(1):86-102.
    • (1995) J Cell Physiol , vol.162 , Issue.1 , pp. 86-102
    • Stenberg, P.E.1    McDonald, T.P.2    Jackson, C.W.3
  • 41
    • 0025541116 scopus 로고
    • Blood platelet formation in vitro. The role of the cytoskeleton in megakaryocyte fragmentation
    • Tablin F, Castro M, Leven RM. Blood platelet formation in vitro: the role of the cytoskeleton in megakaryocyte fragmentation. J Cell Sci. 1990;97(1):59-70. (Pubitemid 120023246)
    • (1990) Journal of Cell Science , vol.97 , Issue.1 , pp. 59-70
    • Tablin, F.1    Castro, M.2    Leven, R.M.3
  • 42
    • 0035901615 scopus 로고    scopus 로고
    • A lineage-restricted and divergent β-tubulin isoform is essential for the biogenesis, structure and function of blood platelets
    • DOI 10.1016/S0960-9822(01)00153-1
    • Schwer HD, Lecine P, Tiwari S, Italiano JE Jr, Hartwig JH, Shivdasani RA. A lineage-restricted and divergent beta-tubulin isoform is essential for the biogenesis, structure and function of blood platelets. Curr Biol. 2001;11(8):579-586. (Pubitemid 32324760)
    • (2001) Current Biology , vol.11 , Issue.8 , pp. 579-586
    • Schwer, H.D.1    Lecine, P.2    Tiwari, S.3    Italiano Jr., J.E.4    Hartwig, J.H.5    Shivdasani, R.A.6
  • 43
    • 0026001739 scopus 로고
    • Characterization of the gene for a proliferation-related phosphoprotein (oncoprotein 18) expressed in high amounts in acute leukemia
    • Melhem RF, Zhu XX, Hailat N, Strahler JR, Hanash SM. Characterization of the gene for a proliferation-related phosphoprotein (oncoprotein 18) expressed in high amounts in acute leukemia. J Biol Chem. 1991;266(27):17747-17753. (Pubitemid 21908004)
    • (1991) Journal of Biological Chemistry , vol.266 , Issue.27 , pp. 17747-17753
    • Melhem, R.F.1    Zhu, X.-X.2    Hailat, N.3    Strahler, J.R.4    Hanash, S.M.5
  • 44
    • 49649090009 scopus 로고    scopus 로고
    • Proteins induced by telomere dysfunction and DNA damage represent biomarkers of human aging and disease
    • Jiang H, Schiffer E, Song Z, et al. Proteins induced by telomere dysfunction and DNA damage represent biomarkers of human aging and disease. Proc Natl Acad Sci U S A. 2008;105(32):11299-11304.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , Issue.32 , pp. 11299-11304
    • Jiang, H.1    Schiffer, E.2    Song, Z.3
  • 45
    • 77953907494 scopus 로고    scopus 로고
    • Thrombocytopenia in patients with myelodysplastic syndromes
    • Bryan J, Jabbour E, Prescott H, Kantarjian H. Thrombocytopenia in patients with myelodysplastic syndromes. Semin Hematol. 2010;47(3):274-280.
    • (2010) Semin Hematol , vol.47 , Issue.3 , pp. 274-280
    • Bryan, J.1    Jabbour, E.2    Prescott, H.3    Kantarjian, H.4
  • 47
    • 30344457028 scopus 로고    scopus 로고
    • Targeting stathmin in prostate cancer
    • DOI 10.1158/1535-7163.MCT-05-0215
    • Mistry SJ, Bank A, Atweh GF. Targeting stathmin in prostate cancer. Mol Cancer Ther. 2005;4(12):1821-1829. (Pubitemid 43056965)
    • (2005) Molecular Cancer Therapeutics , vol.4 , Issue.12 , pp. 1821-1829
    • Mistry, S.J.1    Bank, A.2    Atweh, G.F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.