Polygenic inheritance of sensorineural hearing loss (Snhl2, -3, and -4) and organ of Corti patterning defect in the ALR/LtJ mouse strain

Hearing Research

Volumn 275, Issue 1-2, 2011, Pages 150-159

  Latoche, Joseph R ^a   Neely, Harold R ^a   Noben Trauth, Konrad ^a  

^a NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUDITORY THRESHOLD; CELLULAR DISTRIBUTION; CHROMOSOME 1; CHROMOSOME 10; CHROMOSOME 6; COCHLEA POTENTIAL; CONTROLLED STUDY; CORTI ORGAN; EVOKED OTOACOUSTIC EMISSION; GENE; GENE EXPRESSION; GENE FUNCTION; GENE IDENTIFICATION; GENE LOCATION; HAIR CELL; LINKAGE ANALYSIS; MOUSE; NONHUMAN; PERCEPTION DEAFNESS; PHENOTYPIC VARIATION; PRIORITY JOURNAL; QUANTITATIVE TRAIT LOCUS; SNHL2 GENE; SNHL3 GENE; SNHL4 GENE;

ALLELES; ANIMALS; CHROMOSOME MAPPING; COCHLEAR DUCT; CROSSES, GENETIC; DISEASE MODELS, ANIMAL; GENOME-WIDE ASSOCIATION STUDY; HAIR CELLS, AUDITORY, OUTER; HEARING LOSS, SENSORINEURAL; HUMANS; LOD SCORE; MICE; MICE, INBRED C3H; MODELS, GENETIC; MULTIFACTORIAL INHERITANCE; ORGAN OF CORTI; PHENOTYPE; QUANTITATIVE TRAIT LOCI;

EID: 79955968283     PISSN: 03785955     EISSN: 18785891     Source Type: Journal    
DOI: 10.1016/j.heares.2010.12.017     Document Type: Article

References (31)

1. Ali G., Santos R.L., John P., Wambangco M.A., Lee K., Ahmad W., Leal S. The mapping of DFNB62, a new locus for autosomal recessive non-syndromic hearing impairment, to chromosome 12p13.2-p11.23. Clin. Genet. 2006, 69:429-433.
2. Chen Z., Montcouquiol M., Calderon R., Jenkins N.A., Copeland N.G., Kelley M.W., Noben-Trauth K. Jxc1/Sobp, encoding a nuclear zinc finger protein, is critical for cochlear growth, cell fate, and patterning of the organ of corti. J. Neurosci. 2008, 28:6633-6641.
3. Drayton M., Noben-Trauth K. Mapping quantitative trait loci for hearing loss in Black Swiss mice. Hear Res. 2006, 212:128-139.
4. Eichler E.E., Flint J., Gibson G., Kong A., Leal S.M., Moore J.H., Nadeau J.H. Missing heritability and strategies for finding the underlying causes of complex disease. Nat. Rev. Genet. 2010, 11:446-450.
5. Jimenez A.M., Stagner B.B., Martin G.K., Lonsbury-Martin B.L. Age-related loss of distortion product otoacoustic emissions in four mouse strains. Hear Res. 1999, 138:91-105.
6. Johnson K.R., Zheng Q.Y. Ahl2, a second locus affecting age-related hearing loss in mice. Genomics 2002, 80:461-464.
7. Johnson K.R., Zheng Q.Y., Erway L.C. A major gene affecting age-related hearing loss is common to at least ten inbred strains of mice. Genomics 2000, 70:171-180.
8. Johnson K.R., Zheng Q.Y., Noben-Trauth K. Strain background effects and genetic modifiers of hearing in mice. Mol. Brain Res. 2006, 1091:79-88.
9. frings mutation underlies early onset hearing impairment in BUB/BnJ mice, a model for the auditory pathology of usher syndrome IIC. Genomics 2005, 85:582-590.
10. Johnson K.R., Longo-Guess C., Gagnon L.H., Yu H., Zheng Q.Y. A locus on distal chromosome 11 (ahl8) and its interaction with Cdh23 ahl underlie the early onset, age-related hearing loss of DBA/2J mice. Genomics 2008, 92:219-225.
11. Kiernan A.E., Cordes R., Kopan R., Gossler A., Gridley T. The Notch ligands DLL1 and JAG2 act synergistically to regulate hair cell development in the mammalian inner ear. Development 2005, 132:4353-4362.
12. Konings A., Van Laer L., Van Camp G. Genetic studies on noise-induced hearing loss: a review. Ear Hear 2009, 30:151-159.
13. Lu X., Borchers A.G., Jolicoeur C., Rayburn H., Baker J.C., Tessier-Lavigne M. PTK7/CCK-4 is a novel regulator of planar cell polarity in vertebrates. Nature 2004, 430:93-98.
14. Manly K.F., Cudmore R.H., Meer J.M. Map manager QTX, cross-platform software for genetic mapping. Mamm. Genome 2001, 12:930-932.
15. Mansour S.L., Twigg S.R., Freeland R.M., Wall S.A., Li C., Wilkie A.O. Hearing loss in a mouse model of Muenke syndrome. Hum. Mol. Genet. 2009, 18:43-50.
16. Martin G.K., Vazquez A.E., Jimenez A.M., Stagner B.B., Howard M.A., Lonsbury-Martin B.L. Comparison of distortion product otoacoustic emissions in 28 inbred strains of mice. Hear Res. 2007, 234:59-72.
17. Mashimo T., Erven A.E., Spiden S.L., Guenet J.L., Steel K.P. Two quantitative trait loci affecting progressive hearing loss in 101/H mice. Mamm. Genome 2006, 17:841-850.
18. McClellan J., King M.C. Genetic heterogeneity in human disease. Cell 2010, 141:210-217.
19. Montcouquiol M., Rachel R.A., Lanford P.J., Copeland N.G., Jenkins N.A., Kelley M.W. Identification of Vangl2 and Scrb1 as planar polarity genes in mammals. Nature 2003, 423:173-177.
20. Statistics and Epidemiology 2010, NIDCD. http://www.nidcd.nih.gov.
21. Noben-Trauth K., Johnson K.R. Inheritance patterns of progressive hearing loss in laboratory strains of mice. Brain Res. 2009, 1277:42-51.
22. Noben-Trauth K., Zheng Q.Y., Johnson K.R. Association of cadherin 23 with polygenic inheritance and genetic modification of sensorineural hearing loss. Nat. Genet. 2003, 35:21-23.
23. Ohlemiller K.K., Lett J.M., Gagnon P.M. Cellular correlates of age-related endocochlear potential reduction in a mouse model. Hear Res. 2006, 220:10-26.
24. Pauley S., Lai E., Fritzsch B. Foxg1 is required for morphogenesis and histogenesis of the mammalian inner ear. Dev. Dyn. 2006, 235:2470-2482.
25. Petkov P.M., Graber J.H., Churchill G.A., DiPetrillo K., King B.L., Paigen K. Evidence of a large-scale functional organization of mammalian chromosomes. PLoS Genet. 2005, 1:e33.
26. Sage C., Huang M., Karimi K., Gutierrez G., Vollrath M.A., Zhang D.S., Garcia-Anoveros J., Hinds P.W., Corwin J.T., Corey D.P., Chen Z.Y. Proliferation of functional hair cells in vivo in the absence of the retinoblastoma protein. Science 2005, 307:1114-1118.
27. Shim K., Minowada G., Coling D.E., Martin G.R. Sprouty2, a mouse deafness gene, regulates cell fate decisions in the auditory sensory epithelium by antagonizing FGF signaling. Dev. Cell. 2005, 8:553-564.
28. Shin J.B., Longo-Guess C.M., Gagnon L.H., Saylor K.W., Dumont R.A., Spinelli K.J., Pagana J.M., Wilmarth P.A., David L.L., Gillespie P.G., Johnson K.R. The R109H variant of fascin-2, a developmentally regulated actin crosslinker in hair-cell stereocilia, underlies early-onset hearing loss of DBA/2J mice. J. Neurosci. 2010, 30:9683-9694.
29. Thys M., Van Camp G. Genetics of otosclerosis. Otol Neurotol 2009, 30:1021-1032.
30. Van Eyken E., Van Camp G., Van Laer L. The complexity of age-related hearing impairment: contributing environmental and genetic factors. Audiol. Neurootol. 2007, 12:345-358.
31. Zheng Q.Y., Johnson K.R., Erway L.C. Assessment of hearing in 80 inbred strains of mice by ABR threshold analyses. Hear Res. 1999, 130:94-107.