Effect of surfactants and pH on naltrexone (NTX) permeation across buccal mucosa

International Journal of Pharmaceutics

Volumn 411, Issue 1-2, 2011, Pages 92-97

  Rai, Vishwas ^a   Tan, Hock S ^b   Michniak Kohn, Bozena ^a,c  

^a RUTGERS UNIVERSITY   (United States)

^b Technology Centre of New Jersey   (United States)

^c Department of Pharmaceutics ^*  (United States)

Author keywords

Brij 58 ; Concentration effect; Enhancement ratio (ER); Naltrexone hydrochloride; Penetration enhancers; Permeability coefficients (K p); pH effect; Pre formulation study; Tween 80

Indexed keywords

ADENOSINE TRIPHOSPHATE; CETOMACROGOL; NALTREXONE; POLYSORBATE 80; SALIVA SUBSTITUTE;

ANIMAL TISSUE; ARTICLE; CHEEK MUCOSA; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG PENETRATION; DRUG TRANSPORT; EX VIVO STUDY; HISTOLOGY; HUMAN; HUMAN TISSUE; IN VITRO STUDY; NONHUMAN; PH; PRIORITY JOURNAL; SWINE; TISSUE ENGINEERING;

ADMINISTRATION, BUCCAL; CETOMACROGOL; DIFFUSION; DRUG DELIVERY SYSTEMS; HUMANS; HYDROGEN-ION CONCENTRATION; MOUTH MUCOSA; NALTREXONE; NARCOTIC ANTAGONISTS; PERMEABILITY; SOLUTIONS; SURFACE-ACTIVE AGENTS;

EID: 79955967924     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.03.046     Document Type: Article

References (40)

1. 2. Archives of Oral Biology 45, 1-12.
2. Benson, H.A.E., 2005. Transdermal drug delivery: penetration enhancement techniques. Current Drug Delivery 2, 23-33. (Pubitemid 40590918)
3. Buyukozturk, F., Benneyan, J., Carrier, R.L., 2009. Effect of emulsion based drug delivery systems on rate of drug release and intestinal permeability enhancement. In: Bioengineering Conference, 2009 IEEE 35th Annual Northeast 1-2.
4. Campisi, G., Giannola, L.I., Florena, A.M., De Caro, V., Schumacher, A., Göttsche, T., Paderni, C., Wolff, A., 2010. Bioavailability in vivo of naltrexone following transbuccal administration by an electronically-controlled intraoral device: a trial on pigs. Journal of Controlled Release 145, 214-220.
5. Comer, S., Collins, E., Kleber, H., Nuwayser, E., Kerrigan, J., Fischman, M., 2002. Depot naltrexone: long-lasting antagonism of the effects of heroin in humans. Psychopharmacology 159, 351-360. (Pubitemid 34143359)
6. Davis, W.W., Pfeiffer, R.R., Quay, J.F., 1970. Normal and promoted gastrointestinal absorption of water-soluble substances I: induced rapidly reversible hyperabsorptive state in the canine fundic stomach pouch. Journal of Pharmaceutical Sciences 59, 960-963.
7. Directive67/548/EEC, 2010. European Commission Environment-Dangerous Substances Directive.
8. Dos Santos, I., Fawaz, F., Lagueny, A.M., Bonini, F., 2003. Improvement of norfloxacin oral bioavailability by EDTA and sodium caprate. International Journal of Pharmaceutics 260, 1-4. (Pubitemid 36724856)
9. Egan, R.W., 1976. Hydrophile-lipophile balance and critical micelle concentration as key factors influencing surfactant disruption of mitochondrial membranes. The Journal of Biological Chemistry 251, 4442-4447.
10. Gal, J.-Y., Fovet, Y., Adib-Yadzi, M., 2001. About a synthetic saliva for in vitro studies. Talanta 53, 1103-1115. (Pubitemid 32231524)
11. Giannola, L.I., De Caro, V., Giandalia, G., Siragusa, M.G., Campisi, G., Florena, A.M., Ciach, T., 2007a. Diffusion of naltrexone across reconstituted human oral epithelium and histomorphological features. European Journal of Pharmaceutics and Biopharmaceutics 65, 238-246. (Pubitemid 46038078)
12. Giannola, L.I., De Caro, V., Giandalia, G., Siragusa, M.G., Tripodo, C., Florena, A.M., Campisi, G., 2007b. Release of naltrexone on buccal mucosa: permeation studies, histological aspects and matrix system design. European Journal of Pharmaceutics and Biopharmaceutics 67, 425-433. (Pubitemid 47211903)
13. Hait, S., Moulik, S., 2001. Determination of critical micelle concentration (CMC) of nonionic surfactants by donor-acceptor interaction with lodine and correlation of CMC with hydrophile-lipophile balance and other parameters of the surfactants. Journal of Surfactants and Detergents 4, 303-309. (Pubitemid 33685952)
14. Helenius, A., Simons, K., 1975. Solubilization of membranes by detergents. Biochimica et Biophysica Acta 415, 29-79.
15. Hussain, M., Aungst, B., Koval, C., Shefter, E., 1988. Improved buccal delivery of opioid analgesics and antagonists with bitterless prodrugs. Pharmaceutical Research 5, 615-618.
16. Hussain, M.A., Aungst, B.J., Kearney, A., Shefter, E., 1987. Buccal and oral bioavailability of naloxone and naltrexone in rats. International Journal of Pharmaceutics 36, 127-130. (Pubitemid 17070782)
17. Ihcworld, 2010. H&E Staining Method and Protocol-Harris.
18. Johansson, F., Olbe, M., Sommarin, M., Larsson, C., 1995. Brij 58, a polyoxyethylene acyl ether, creates membrane vesicles of uniform sidedness. A new tool to obtain inside-out (cytoplasmic side-out) plasmamembrane vesicles. The Plant Journal 7, 165-173.
19. Kaufer, D.I., DeKosky, S.T., 2005. Principal of the pharmacotherapy of substances abuse disorders. Neurobiology of Mental Illness, 1272.
20. a's and partition coefficients and their significance in clinical practice. Drug and Alcohol Dependence 1, 103-114.
21. a's and partition and drug distribution coefficients of narcotics and narcotic antagonists and their pH and temperature dependence. Journal of Medicinal Chemistry 18, 647-655.
22. Lairon, D., Nalbone, G., Lafont, H., Leonardi, J., Domingo, N., Hauton, J.C., Verger, R., 1978. Inhibition of lipase adsorption at interfaces. Role of bile salt micelles and colipase. Biochemistry 17, 205-208.
23. Lee, Y.K., Park, S.W., Kim, Y.K., Kim, D.J., Jeong, J., Myrick, H., Kim, Y.H., 2005. Effects of naltrexone on the ethanol-induced changes in the rat central dopaminergic system. Alcohol and Alcoholism 40, 297-301. (Pubitemid 40895426)
24. McBain, J.W., Wilder, A.G., Merrill, R.C., 1948. Solubilization of water-insoluble dye by colloidal electrolytes and non-ionizing detergents. The Journal of Physical and Colloid Chemistry 52, 12-22.
25. Metcalf, M.D., Coop, A., 2005. Kappa opioid antagonists: past successes and future prospects. AAPS Journal 7, E704-E722.
26. Milewski, M., Stinchcomb, A., 2011. Vehicle composition influence on the microneedle-enhanced transdermal flux of naltrexone hydrochloride. Pharmaceutical Research 28, 124-134.
27. Miraglia, D., Rodríguez, J., Minardi, R., Schulz, P., 2010. Critical micelle concentration and HLB of the sodium oleate- hexadecyltrimethylammonium bromide mixed system. Journal of Surfactants and Detergents, 1-8.
28. Oncken, C., Van Kirk, J., Kranzler, H.R., 2001. Adverse effects of oral naltrexone: analysis of data from two clinical trials. Psychopharmacology 154, 397-402. (Pubitemid 32260899)
29. Osborne, D.W., Henke, J.J., 1997. Skin permeation enhancers cited in technical literature. Pharmaceutical Technology (November), 58-66. (Pubitemid 27509149)
30. Palmgren, M.G., Sommarin, M., Ulvskov, P., Larsson, C., 1990. Effect of detergents on the H+-ATPase activity of inside-out and right-side-out plant plasmamembrane vesicles. Biochimica et Biophysica Acta (BBA)-Biomembranes 1021, 133-140. (Pubitemid 20037561)
31. Rama Prasad, Y.V., Minamimoto, T., Yoshikawa, Y., Shibata, N., Mori, S., Matsuura, A., Takada, K., 2004. In situ intestinal absorption studies on low molecular weight heparin in rats using Labrasol as absorption enhancer. International Journal of Pharmaceutics 271, 225-232.
32. Rathbone, M.J., Drummond, B.K., Tucker, I.G., 1994. The oral cavity as a site for systemic drug delivery. Advanced Drug Delivery Reviews 13, 1-22. (Pubitemid 24032039)
33. Shore, P.A., Brodie, B.B., Hogben, C.A.M., 1957. The gastric secretion of drugs: a pH partition hypothesis. Journal of Pharmacology and Experimental Therapeutics 119, 361-369.
34. Siegel, A., 1984. The structure and function of oral mucosa. In: Meyer, J., Squier, C.A., Gerson, S.J. (Eds.), Permeability of the Oral Mucosa. Pergamon Press, Oxford, pp. 98-104.
35. Sinclair, J.D., 2001. Evidence about the use of naltrexone and for different ways of using it in the treatment of alcoholism. Alcohol and Alcoholism 36, 2-10. (Pubitemid 32099659)
36. Squier, C.A., Hall, B.K., 1984. The permeability of mammalian nonkeratinized oral epithelia to horseradish peroxidase applied in vivo and in vitro. Archives of Oral Biology 29, 45-50.
37. Tambwekar, K.R., Kakariya, R.B., Garg, S., 2003. A validated high performance liquid chromatographic method for analysis of nicotine in pure form and from formulations. Journal of Pharmaceutical and Biomedical Analysis 32, 441-450. (Pubitemid 38021834)
38. Valiveti, S., Paudel, K.S., Hammell, D.C., Hamad, M.O., Chen, J., Crooks, P.A., Stinchcomb, A.L., 2005. In vitro in vivo correlation of transdermal naltrexone prodrugs in hairless guinea pigs. Pharmaceutical Research 22, 981-989.
39. Volkering, F., Breure, A.M., van Andel, J.G., Rulkens, W.H., 1995. Influence of non-ionic surfactants on bioavailability and biodegradation of polycyclic aromatic hydrocarbons. Applied and Environmental Microbiology 61, 1699-1705.
40. Williams, A.C., Barry, B.W., 2004. Penetration enhancers. Advanced Drug Delivery Reviews 56, 603-618. (Pubitemid 38326936)