Downregulation of matrix metalloproteinase-2 in corneal fibroblasts by interleukin-1 receptor antagonist released from corneal epithelial cells

Investigative Ophthalmology and Visual Science

Volumn 51, Issue 12, 2010, Pages 6286-6293

  Ko, Ji Ae ^a   Yanai, Ryoji ^a   Chikama, Tai ichiro ^a   Nishida, Teruo ^a  

^a YAMAGUCHI UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; COLLAGEN; GELATINASE A; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38; STRESS ACTIVATED PROTEIN KINASE;

ARTICLE; ARTIFICIAL MEMBRANE; CELL TRANSFORMATION; COLLAGEN VITRIGEL MEMBRANE; CONTROLLED STUDY; CORNEA; CORNEA EPITHELIUM; CORNEA FIBROBLAST; DOWN REGULATION; EPITHELIUM CELL; FIBROBLAST; FIBROBLAST CULTURE; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SIMIAN VIRUS 40;

CELL LINE; CELL LINE, TRANSFORMED; COCULTURE TECHNIQUES; CORNEA; DOWN-REGULATION; EPITHELIUM, CORNEAL; FIBROBLASTS; HUMANS; IMMUNOBLOTTING; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; MATRIX METALLOPROTEINASE 2; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; RECEPTORS, INTERLEUKIN-1; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; TRANSFECTION;

EID: 79955948149     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.09-4753     Document Type: Article

References (43)

1. Hart GW. Biosynthesis of glycosaminoglycans during corneal development. J Biol Chem. 1976;251:6513-6521.
2. Wilson SE, Liu JJ, Mohan RR. Stromal-epithelial interactions in the cornea. Prog Retin Eye Res. 1999;18:293-309.
3. Jester JV, Barry-Lane PA, Lind GJ, Petroll WM, Garana R, Cavanagh HD. Corneal keratocytes: in situ and in vitro organization of cytoskeletal contractile proteins. Invest Ophthalmol Vis Sci. 1994; 35:730-743.
4. Jester JV, Barry-Lane PA, Cavanagh HD, Petroll WM. Induction of alpha-smooth muscle actin expression and myofibroblast transformation in cultured corneal keratocytes. Cornea. 1996; 15:505-516.
5. Jain M, He Q, Lee WS, et al. Role of CD44 in the reaction of vascular smooth muscle cells to arterial wall injury. J Clin Invest. 1996;97:596-603.
6. Arthur MJ. Fibrosis and altered matrix degradation. Digestion. 1998;59:376-380.
7. Ramadori G, Knittel T, Saile B. Fibrosis and altered matrix synthesis. Digestion. 1998;59:372-375.
8. Fini ME, Stramer BM. How the cornea heals: cornea-specific repair mechanism affecting surgical outcomes. Cornea. 2005;24:S2-S11.
9. Fini M, Girard M. Expression of collagenolytic/gelatinolytic metalloproteinases by normal cornea. Invest Ophthalmol Vis Sci. 1990; 31:779-788.
10. Girard M, Matsubara M, Fini M. Transforming growth factor- and interleukin-1 modulate metalloproteinase expression by corneal stromal cells. Invest Ophthalmol Vis Sci. 1991;32:2441-2454.
11. Lu P, Ye H, Maeda M, Azar D. Immunolocalization and gene expression of matrilysin during corneal wound healing. Invest Ophthalmol Vis Sci. 1999;40:20-27.
12. Azar D, Hahn T, Jain S, Yeh Y, Stelter-Stevenson W. Matrix metalloproteases are expressed during wound healing after excimer laser keratectomy. Cornea. 1996;15:18-24.
13. Ye H, Azar D. Expression of gelatinases A and B, and TIMPS 1 and 2 during corneal wound healing. Invest Ophthalmol Vis Sci. 1998; 39:913-921.
14. Paul R, Tarlton J, Purslow P, et al. Biomechanical and biochemical study of a standardized wound healing model. Int J Biochem Cell Biol. 1997;29:211-220.
15. Fini M, Girard M, Matsubara M. Collagenolytic/gelatinolytic enzymes in corneal wound healing. Acta Ophthalmol. 1992;202: 26-33.
16. Smith V, Hoh B, Littleton M, Easty D. Over-expression of a gelatinase A activity in keratoconus. Eye. 1995;9:429-433.
17. Ko JA, Liu Y, Yanai R, Chikama T, Takezawa T, Nishida T. Upregulation of tight-junctional proteins in corneal epithelial cells by corneal fibroblasts in collagen vitrigel cultures. Invest Ophthalmol Vis Sci. 2008;49:113-119.
18. Ko JA, Yanai R, Morishige N, Takezawa T, Nishida T. Upregulation of connexin43 expression in corneal fibroblasts by corneal epithelial cells. Invest Ophthalmol Vis Sci. 2009;50:2054-2060.
19. Ko JA, Yanai R, Nishida T. IGF-1 released by corneal epithelial cells induces up-regulation of N-cadherin in corneal fibroblasts. J Cell Physiol. 2009;221:254-261.
20. Li DQ, Tseng SC. Three patterns of cytokine expression potentially involved in epithelial-fibroblast interactions of human ocular surface. J Cell Physiol. 1995;163:61-79.
21. Rosenbaum JT, Samples JR, Hefeneider SH, Howes EL. Ocular inflammatory effects of intravitreal interleukin 1. Arch Ophthalmol. 1987;105:1117-1120.
22. Ferrick MR, Thurau SR, Oppenheim MH, et al. Ocular inflammation stimulated by intravitreal interleukin-8 and interleukin-1. Invest Ophthalmol Vis Sci. 1991;32:1534-1539.
23. Fleisher LN, Ferrell JB, McGahan MC. Synergistic uveitic effects of tumor necrosis factor- and interleukin-1. Invest Ophthalmol Vis Sci. 1992;33:2120-2127.
24. Hoekzema R, Murray PI, Van Haren MAC, Helle M, Kijilstra A. Analysis of interleukin-6 in endotoxin-induced uveitis. Invest Ophthalmol Vis Sci. 1991;32:88-95.
25. Rosenbaum JR, Howes EL Jr, Rubin RM, Samples JR. Ocular inflammatory effect of intravitreally-injected tumor necrosis factor. Am J Pathol. 1988;133:47-53.
26. Fleisher LN, Ferrell JB, McGahan MC. Ocular inflammatory effects of intravitreally injected tumor necrosis factor- and endotoxin. Inflammation. 1990;14:325-335.
27. Alexander CM, Werb Z. Extracellular matrix degradation. In: Hay ED, ed. Cell Biology of Extracellular Matrix. New York: Plenum Press; 1991:255-302.
28. Dayer JM, Passwell JH, Schneeberger EE, Krane SM. Interactions among rheumatoid synovial cells and monocyte-macrophages: production of collagenase-stimulating factor by human monocytes exposed to concavalin A or immunoglobulin Fc fragments. J Clin Invest. 1980;124:1712-1720.
29. Arend WP, Welgus HG, Thompson RC, Eisenberg SP. Biological properties of recombinant human monocyte-derived interleukin 1 receptor antagonist. J Clin Invest. 1990;85:1694-1697.
30. Lu Y, Liu Y, Fukuda K, Nakamura Y, Kumagai N, Nishida T. Inhibition by triptolide of chemokine, proinflammatory cytokine, and adhesion molecule expression induced by lipopolysaccharide in corneal fibroblasts. Invest Ophthalmol Vis Sci. 2006;47:3796-3800.
31. Araki-Sasaki K, Ohashi Y, Sasabe T, et al. An SV40-immortalized human corneal epithelial cell line and its characterization. Invest Ophthalmol Vis Sci. 1995;36:614-621.
32. Takezawa T, Ozaki K, Nitani A, Takabayashi C, Shimo-Oka T. Collagen vitrigel: a novel scaffold that can facilitate a three-dimensional culture for reconstructing organoids. Cell Transplant. 2004; 13:463-473.
33. Matsubara M, Girard MT, Kublin CL, Cintron C, Fini ME. Differential roles for two gelatinolytic enzymes of the matrix metalloproteinase family in the remodeling cornea. Dev Biol. 1991;147:425-439.
34. Kenney MC, Chwa M, Alba A, Saghizadeh M, Huang ZS, Brown DJ. Localisation of TIMP-1, TIMP-2, TIMP-3, gelatinase A and gelatinase B in pathological human corneas. Curr Eye Res. 1998;1998:238-246.
35. Ottino P, Taheri F, Bazen HE. Platelet-activating factor induces the gene expression of TIMP-1, -2, and PAI-1: imbalance between the gene expression of MMP-9 and TIMP-1 and -2. Exp Eye Res. 2002; 74:393-402.
36. Kjeldsen L, Sengelov H, Lollike K, Nielsen MH, Borregaard N. Isolation and characterization of gelatinase granules from human neutrophils. Blood. 1994;83:1640-1649.
37. Girard MT, Matsubara M, Kublin C, Tessier MJ, Cintron C, Fini ME. Stromal fibroblasts synthesize collagenase and stromelysin during long-term tissue remodeling. J Cell Sci. 1993;104:1001-1011.
38. Daniels JT, Limb GA, Saarialho-Kere U, Murphy G, Khaw PT. Human corneal epithelial cells require MMP-1 for HGF-mediatedmigration on collagen I. Invest Ophthalmol Vis Sci. 2003;44:1048-1055.
39. Matsubara M, Zieske JD, Fini ME. Mechanism of basement membrane dissolution preceding corneal ulceration. Invest Ophthalmol Vis Sci. 1991;32:3221-3237.
40. Fini ME, Parks WC, Rinehart WB, et al. Role of matrix metalloproteinases in failure to re-epithelialize after corneal injury. Am J Pathol. 1996;149:1287-1302.
41. Sun CC, Pang JHS, Cheng CY, et al. Interleukin-1 receptor antagonist (IL-1RA) prevents apoptosis in ex vivo expansion of human limbal epithelial cells cultivated on human amniotic membrane. Stem Cells. 2006;24:2130-2139.
42. Dripps DJ, Brandhuber BJ, Thompson RC, et al. Interleukin (IL-1) receptor antagonist binds to the 80-kDa IL-1 receptor but does not initiate IL-1 signal transduction. J Biol Chem. 1991;266:10331-10336.
43. Granowitz EV, Clark BD, Mancilla J, et al. Interleukin-1 receptor antagonist competitively inhibits the binding of interleukin-1 to the type II interleukin-1 receptor. J Biol Chem. 1991;266:14147-14150.