Poly(ethylene oxide/propylene oxide) copolymer thermo-reversible gelling system for the enhancement of intranasal zidovudine delivery to the brain

International Journal of Pharmaceutics

Volumn 411, Issue 1-2, 2011, Pages 1-9

  Ved, Parag M ^a   Kim, Kwonho ^a  

^a ST JOHN'S UNIVERSITY   (United States)

Author keywords

Brain uptake; Nasal drug delivery; Olfactory pathway; Thermoreversible gel; Zidovudine

Indexed keywords

N TRIDECYL BETA DEXTRO MALTOSID; NOSE SPRAY; PENETRATION ENHANCING AGENT; POLOXAMER; UNCLASSIFIED DRUG; ZIDOVUDINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; CEREBELLUM; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG CEREBROSPINAL FLUID LEVEL; DRUG CONCENTRATION; DRUG DELIVERY SYSTEM; DRUG DOSAGE FORM COMPARISON; DRUG FORMULATION; DRUG PENETRATION; DRUG STABILITY; EXPERIMENTAL RABBIT; GELATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; NONHUMAN; NOSE MUCOSA; OLFACTORY BULB; OLFACTORY TRACT; PRIORITY JOURNAL;

ADMINISTRATION, INTRANASAL; ANIMALS; ANTI-HIV AGENTS; BIOLOGICAL TRANSPORT; BRAIN; COLD TEMPERATURE; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; EPOXY COMPOUNDS; ETHYLENE OXIDE; EXCIPIENTS; GELS; HOT TEMPERATURE; MALE; NOSE; OLFACTORY PATHWAYS; POLOXAMER; POLYETHYLENE GLYCOLS; POLYMERS; RABBITS; ZIDOVUDINE;

EID: 79955945541     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.02.040     Document Type: Article

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