Diamine oxidase, a plasma biomarker in rats to GI tract toxicity of oral fluorouracil anti-cancer drugs

Toxicology

Volumn 217, Issue 2-3, 2006, Pages 233-239

  Moriyama, Kenji ^a   Kouchi, Yasuhide ^a   Morinaga, Hidenobu ^a   Irimura, Kenji ^a   Hayashi, Taiji ^a   Ohuchida, Akinobu ^a   Goto, Tetsuhiro ^b   Yoshizawa, Yasuo ^b  

^a TAIHO PHARMACEUTICAL CO LTD   (Japan)

^b SHOWA UNIVERSITY FUJIGAOKA HOSPITAL   (Japan)

Author keywords

5 FU; Diamine oxidase; GI tract toxicity; Rat

Indexed keywords

5 CHLORO 2,4 DIHYDROXYPYRIDINE; 5 CHLORO 2,4 DIHYDROXYPYRIDINE PLUS OXONATE POTASSIUM PLUS TEGAFUR; AMINE OXIDASE (COPPER CONTAINING); ANTINEOPLASTIC AGENT; BIOLOGICAL MARKER; TEGAFUR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; ENZYME LOCALIZATION; GASTROINTESTINAL TOXICITY; HISTOPATHOLOGY; INTESTINE VILLUS ATROPHY; JEJUNUM MUCOSA; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ADMINISTRATION, ORAL; AMINE OXIDASE (COPPER-CONTAINING); ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; APOPTOSIS; BIOLOGICAL MARKERS; BODY WEIGHT; DIHYDROURACIL DEHYDROGENASE (NADP); FLUOROURACIL; INTESTINAL MUCOSA; JEJUNAL DISEASES; MALE; OROTATE PHOSPHORIBOSYLTRANSFERASE; OXONIC ACID; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; TEGAFUR;

ANIMALIA;

EID: 28844501982     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2005.09.017     Document Type: Article

References (14)

1. L. D'Agostino, C. Ciacci, B. Daniel, M.V. Barone, R. Sollazzo, and G. Mazzacca Postheparin plasma diamine oxidase in subjects with small bowel mucosal atrophy Dig. Dis. Sci. 32 1987 313 317
2. L. D'Agostino, B. Daniele, S. Pignata, G. D'Argenio, and G. Mazzacca Modifications in enterocyte diamine oxidase distribution induced by heparin in the rat Biochem. Pharmacol. 38 1989 47 49
3. L. D'Agostino, S. Pignata, B. Daniele, R. Ventriglia, G. Ferrari, C. Ferraro, S. Spagnuolo, P.E. Lucchelli, and G. Mazzacca Release of diamine oxidase into plasma by glycosaminoglycans in rats Biochim. Biophys. Acta 993 1989 228 232
4. N. Horikoshi, Y. Mitachi, Y. Sakata, K. Sugimachi, and T. Taguchi S-1, a new oral fluoropyridine, is very active in patients with advanced gastric cancer (early Phase II study) Proc. Am. Soc. Clin. Oncol. 15 1996 466
5. G.D. Luk, T.M. Bayless, and S.B. Baylin Diamine oxidase (Histaminase). A circulating marker for rat intestinal mucosal maturation and integrity J. Clin. Invest. 66 1980 66 70
6. G.D. Luk, T.M. Bayless, and S.B. Baylin Plasma post heparin diamine oxidase. Sensitive provocative test for quantitating length of acute intestinal mucosal injury in the rat J. Clin. Invest. 71 1983 1308 1315
7. G.D. Luk, W.P. Vaughan, P.J. Burke, and S.B. Baylin Diamine oxidase as a plasma marker of rat intestinal mucosal injury and regeneration after administration of 1-β-d-arabinofuranosylcytosine Cancer Res. 41 1981 2334 2337
8. T. Mayumi, J. Takezawa, H. Takahashi, N. Kuwayama, T. Fukuoka, K. Yamada, M. Nkao, and K. Takagi Evaluation of intestinal mucosal integrity using serum diamine oxidase Dig. Absorp. 20 1997 143 148
9. T. Shirasaka, S. Shimamoto, and M. Fukushima Inhibition by oxonic acid of gastrointestinal toxicity of 5-fluorouracil without loss by its antitumor activity in rats Cancer Res. 53 1993 4004 4009
10. T. Shirasaka, S. Shimamoto, H. Ohsimo, M. Yamaguchi, T. Kato, K. Yonekura, and M. Fukushima Development of a novel form of an oral 5-fluorouracil derivative (S-1) directed to the potentiation of the tumor selective cytotoxicity of 5-fluorouracil by two biochemical modulators Anticancer Drugs 7 1996 548 557
11. K. Takagi, M. Nakao, Y. Ogura, T. Nabeshima, and A. Kunii Sensitive colorimetric assay of serum diamine oxidase Clin. Chim. Acta 226 1994 67 75
12. T. Takechi, K. Nakao, J. Uchida, A. Mita, K. Toko, S. Yakeda, N. Unemi, and T. Shirasaka Antitumor activity and low intestinal toxicity of S-1, a new formulation of oral tegafur, in experimental tumor models in rats Cancer Chemother. Pharmacol. 39 1997 205 211
13. T. Tsujikawa, K. Uda, T. Ihara, T. Inoue, A. Andoh, Y. Fujiyama, and T. Bamba Changes in serum diamine oxidase activity during chemotherapy in patients with hematological malignancies Cancer Lett. 147 1999 195 198
14. MC.J. Wolvekamp, and RW.F. de Bruin Diamine oxidase: an overview of historical, biochemical and functional aspects Dig. Dis. 12 1994 2 14