-
1
-
-
26844555183
-
Molecular genetic pathways in Parkinson's disease: A review
-
DOI 10.1042/CS20050106
-
Jain S, Wood NW, Healy DG. Molecular genetic pathways in Parkinson's disease: a review. Clin Sci (Lond) 2005; 109: 355-364. (Pubitemid 41445243)
-
(2005)
Clinical Science
, vol.109
, Issue.4
, pp. 355-364
-
-
Jain, S.1
Wood, N.W.2
Healy, D.G.3
-
2
-
-
63149090431
-
Parkinson's disease: From monogenic forms to genetic susceptibility factors
-
Lesage S, Brice A. Parkinson's disease: from monogenic forms to genetic susceptibility factors. Hum Mol Genet 2009; 18: R48-R59.
-
(2009)
Hum Mol Genet
, vol.18
-
-
Lesage, S.1
Brice, A.2
-
3
-
-
68649110032
-
Mendelian forms of Parkinson's disease
-
Gasser T. Mendelian forms of Parkinson's disease. Biochim Biophys Acta 2009; 1792: 587-596.
-
(2009)
Biochim Biophys Acta
, vol.1792
, pp. 587-596
-
-
Gasser, T.1
-
4
-
-
33750594065
-
Genetics of Parkinson's disease and parkinsonism
-
DOI 10.1002/ana.21022
-
Hardy J, Cai H, Cookson MR, Gwinn-Hardy K, Singleton A. Genetics of Parkinson's disease and parkinsonism. Ann Neurol 2006; 60: 389-398. (Pubitemid 44684974)
-
(2006)
Annals of Neurology
, vol.60
, Issue.4
, pp. 389-398
-
-
Hardy, J.1
Cai, H.2
Cookson, M.R.3
Gwinn-Hardy, K.4
Singleton, A.5
-
5
-
-
69149089036
-
Molecular pathogenesis of Parkinson disease: Insights from genetic studies
-
Gasser T. Molecular pathogenesis of Parkinson disease: insights from genetic studies. Expert Rev Mol Med 2009; 11: e22.
-
(2009)
Expert Rev Mol Med
, vol.11
-
-
Gasser, T.1
-
6
-
-
0036550101
-
Parkinson-Like Neurodegeneration Induced by Targeted Overexpression of α-Synuclein in the Nigrostriatal System
-
Kirik D, Rosenblad C, Burger C, Lundberg C, Johansen TE, Muzyczka N et al. Parkinson-like neurodegeneration induced by targeted overexpression of alpha-synuclein in the nigrostriatal system. J Neurosci 2002; 22: 2780-2791. (Pubitemid 37465827)
-
(2002)
Journal of Neuroscience
, vol.22
, Issue.7
, pp. 2780-2791
-
-
Kirik, D.1
Rosenblad, C.2
Burger, C.3
Lundberg, C.4
Johansen, T.E.5
Muzyczka, N.6
Mandel, R.J.7
Bjorklund, A.8
-
7
-
-
33947127695
-
Long-term consequences of human alpha-synuclein overexpression in the primate ventral midbrain
-
DOI 10.1093/brain/awl382
-
Eslamboli A, Romero-Ramos M, Burger C, Bjorklund T, Muzyczka N, Mandel RJ et al. Long-term consequences of human alpha-synuclein overexpression in the primate ventral midbrain. Brain 2007; 130: 799-815. (Pubitemid 46410741)
-
(2007)
Brain
, vol.130
, Issue.3
, pp. 799-815
-
-
Eslamboli, A.1
Romero-Ramos, M.2
Burger, C.3
Bjorklund, T.4
Muzyczka, N.5
Mandel, R.J.6
Baker, H.7
Ridley, R.M.8
Kirik, D.9
-
8
-
-
0345269757
-
Nigrostriatal α-synucleinopathy induced by viral vector-mediated overexpression of human α-synuclein: A new primate model of Parkinson's disease
-
DOI 10.1073/pnas.0536383100
-
Kirik D, Annett LE, Burger C, Muzyczka N, Mandel RJ, Bjorklund A. Nigrostriatal alpha-synucleinopathy induced by viral vector-mediated overexpression of human alpha-synuclein: a new primate model of Parkinson's disease. Proc Natl Acad Sci USA 2003; 100: 2884-2889. (Pubitemid 36297593)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.5
, pp. 2884-2889
-
-
Kirik, D.1
Annett, L.E.2
Burger, C.3
Muzyczka, N.4
Mandel, R.J.5
Bjorklund, A.6
-
9
-
-
0041625923
-
Neuropathology and neurodegeneration in rodent brain induced by lentiviral vector-mediated overexpression of α-synuclein
-
Lauwers E, Debyser Z, Van Dorpe J, De Strooper B, Nuttin B, Baekelandt V. Neuro-pathology and neurodegeneration in rodent brain induced by lentiviral vector-mediated overexpression of alpha-synuclein. Brain Pathol 2003; 13: 364-372. (Pubitemid 36975826)
-
(2003)
Brain Pathology
, vol.13
, Issue.3
, pp. 364-372
-
-
Lauwers, E.1
Debyser, Z.2
Van Dorpe, J.3
De Strooper, B.4
Nuttin, B.5
Baekelandt, V.6
-
10
-
-
0036202813
-
Dopaminergic cell loss induced by human A30P α-synuclein gene transfer to the rat substantia nigra
-
DOI 10.1089/10430340252837206
-
Klein RL, King MA, Hamby ME, Meyer EM. Dopaminergic cell loss induced by human A30P alpha-synuclein gene transfer to the rat substantia nigra. Hum Gene Ther 2002; 13: 605-612. (Pubitemid 34264311)
-
(2002)
Human Gene Therapy
, vol.13
, Issue.5
, pp. 605-612
-
-
Klein, R.L.1
King, M.A.2
Hamby, M.E.3
Meyer, E.M.4
-
11
-
-
34548741834
-
RAAV-mediated nigral human parkin over-expression partially ameliorates motor deficits via enhanced dopamine neurotransmission in a rat model of Parkinson's disease
-
DOI 10.1016/j.expneurol.2007.06.019, PII S0014488607002592
-
Manfredsson FP, Burger C, Sullivan LF, Muzyczka N, Lewin AS, Mandel RJ. rAAV-mediated nigral human parkin over-expression partially ameliorates motor deficits via enhanced dopamine neurotransmission in a rat model of Parkinson's disease. Exp Neurol 2007; 207: 289-301. (Pubitemid 47429661)
-
(2007)
Experimental Neurology
, vol.207
, Issue.2
, pp. 289-301
-
-
Manfredsson, F.P.1
Burger, C.2
Sullivan, L.F.3
Muzyczka, N.4
Lewin, A.S.5
Mandel, R.J.6
-
12
-
-
33749453510
-
Parkin Protects against Neurotoxicity in the 6-Hydroxydopamine Rat Model for Parkinson's Disease
-
DOI 10.1016/j.ymthe.2006.06.009, PII S152500160600253X
-
Vercammen L, Van der Perren A, Vaudano E, Gijsbers R, Debyser Z, Van den Haute C et al. Parkin protects against neurotoxicity in the 6-hydroxydopamine rat model for Parkinson's disease. Mol Ther 2006; 14: 716-723. (Pubitemid 44507714)
-
(2006)
Molecular Therapy
, vol.14
, Issue.5
, pp. 716-723
-
-
Vercammen, L.1
Van Der Perren, A.2
Vaudano, E.3
Gijsbers, R.4
Debyser, Z.5
Van Den Haute, C.6
Baekelandt, V.7
-
13
-
-
37349129281
-
The parkin protein as a therapeutic target in Parkinson's disease
-
DOI 10.1517/14728222.11.12.1543
-
Winklhofer KF. The parkin protein as a therapeutic target in Parkinson's disease. Expert Opin Ther Targets 2007; 11: 1543-1552. (Pubitemid 350285004)
-
(2007)
Expert Opinion on Therapeutic Targets
, vol.11
, Issue.12
, pp. 1543-1552
-
-
Winklhofer, K.F.1
-
14
-
-
0032143368
-
Characterization of behavioral and neurodegenerative changes following partial lesions of the nigrostriatal dopamine system induced by intrastriatal 6-hydroxydopamine in the rat
-
DOI 10.1006/exnr.1998.6848
-
Kirik D, Rosenblad C, Bjorklund A. Characterization of behavioral and neurodegenera-tive changes following partial lesions of the nigrostriatal dopamine system induced by intrastriatal 6-hydroxydopamine in the rat. Exp Neurol 1998; 152: 259-277. (Pubitemid 28419264)
-
(1998)
Experimental Neurology
, vol.152
, Issue.2
, pp. 259-277
-
-
Kirik, D.1
Rosenblad, C.2
Bjorklund, A.3
-
15
-
-
0021273328
-
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in the common marmoset
-
Jenner P, Rupniak NM, Rose S, Kelly E, Kilpatrick G, Lees A et al. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in the common marmoset. Neurosci Lett 1984; 50: 85-90. (Pubitemid 14074930)
-
(1984)
Neuroscience Letters
, vol.50
, Issue.1-3
, pp. 85-90
-
-
Jenner, P.1
Rupniak, N.M.J.2
Rose, R.3
-
17
-
-
0034637267
-
Potentiated and preferential effects of combined paraquat and maneb on nigrostriatal dopamine systems: Environmental risk factors for Parkinson's disease?
-
DOI 10.1016/S0006-8993(00)02496-3, PII S0006899300024963
-
Thiruchelvam M, Brockel BJ, Richfield EK, Baggs RB Cory-Slechta DA. Potentiated and preferential effects of combined paraquat and maneb on nigrostriatal dopamine systems: environmental risk factors for Parkinson's disease? Brain Res 2000; 873: 225-234. (Pubitemid 30619046)
-
(2000)
Brain Research
, vol.873
, Issue.2
, pp. 225-234
-
-
Thiruchelvam, M.1
Brockel, B.J.2
Richfield, E.K.3
Baggs, R.B.4
Cory-Slechta, D.A.5
-
18
-
-
26844527655
-
Genetic mouse models of Parkinsonism: Strengths and limitations
-
DOI 10.1602/neurorx.2.3.495
-
Fleming SM, Fernagut PO, Chesselet MF. Genetic mouse models of parkinsonism: strengths and limitations. NeuroRx 2005; 2: 495-503. (Pubitemid 41444883)
-
(2005)
NeuroRx
, vol.2
, Issue.3
, pp. 495-503
-
-
Fleming, S.M.1
Fernagut, P.-O.2
Chesselet, M.-F.3
-
19
-
-
34447570901
-
Age-dependent cognitive decline and amygdala pathology in α-synuclein transgenic mice
-
DOI 10.1016/j.neurobiolaging.2006.06.013, PII S0197458006002235
-
Freichel C, Neumann M, Ballard T, Muller V, Woolley M, Ozmen L et al. Age-dependent cognitive decline and amygdala pathology in alpha-synuclein transgenic mice. Neurobiol Aging 2007; 28: 1421-1435. (Pubitemid 47081234)
-
(2007)
Neurobiology of Aging
, vol.28
, Issue.9
, pp. 1421-1435
-
-
Freichel, C.1
Neumann, M.2
Ballard, T.3
Muller, V.4
Woolley, M.5
Ozmen, L.6
Borroni, E.7
Kretzschmar, H.A.8
Haass, C.9
Spooren, W.10
Kahle, P.J.11
-
20
-
-
0141891953
-
Parkin-deficient Mice Exhibit Nigrostriatal Deficits but not Loss of Dopaminergic Neurons
-
DOI 10.1074/jbc.M308947200
-
Goldberg MS, Fleming SM, Palacino JJ, Cepeda C, Lam HA, Bhatnagar A et al. Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons. J Biol Chem 2003; 278: 43628-43635. (Pubitemid 37345989)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.44
, pp. 43628-43635
-
-
Goldberg, M.S.1
Fleming, S.M.2
Palacino, J.J.3
Cepeda, C.4
Lam, H.A.5
Bhatnagar, A.6
Meloni, E.G.7
Wu, N.8
Ackerson, L.C.9
Klapstein, G.J.10
Gajendiran, M.11
Roth, B.L.12
Chesselet, M.-F.13
Maidment, N.T.14
Levine, M.S.15
Shen, J.16
-
21
-
-
10744221310
-
Parkin gene inactivation alters behaviour and dopamine neurotransmission in the mouse
-
DOI 10.1093/hmg/ddg239
-
Itier JM, Ibanez P, Mena MA, Abbas N, Cohen-Salmon C, Bohme GA et al. Parkin gene inactivation alters behaviour and dopamine neurotransmission in the mouse. Hum Mol Genet 2003; 12: 2277-2291. (Pubitemid 37160872)
-
(2003)
Human Molecular Genetics
, vol.12
, Issue.18
, pp. 2277-2291
-
-
Itier, J.-M.1
Ibanez, P.2
Mena, M.A.3
Abbas, N.4
Cohen-Salmon, C.5
Bohme, G.A.6
Laville, M.7
Pratt, J.8
Corti, O.9
Pradier, L.10
Ret, G.11
Joubert, C.12
Periquet, M.13
Araujo, F.14
Negroni, J.15
Casarejos, M.J.16
Canals, S.17
Solano, R.18
Serrano, A.19
Gallego, E.20
Sanchez, M.21
Denefle, P.22
Benavides, J.23
Tremp, G.24
Rooney, T.A.25
Brice, A.26
Garcia De Yebenes, J.27
more..
-
22
-
-
36949031267
-
α-Synucleinopathy models and human neuropathology: Similarities and differences
-
DOI 10.1007/s00401-007-0302-x
-
Kahle PJ. alpha-Synucleinopathy models and human neuropathology: similarities and differences. Acta Neuropathol 2008; 115: 87-95. (Pubitemid 350238669)
-
(2008)
Acta Neuropathologica
, vol.115
, Issue.1
, pp. 87-95
-
-
Kahle, P.J.1
-
23
-
-
37549032800
-
In vivo gene delivery for development of mammalian models for Parkinson's disease
-
Ulusoy A, Bjorklund T, Hermening S, Kirik D. In vivo gene delivery for development of mammalian models for Parkinson's disease. Exp Neurol 2008; 209: 89-100.
-
(2008)
Exp Neurol
, vol.209
, pp. 89-100
-
-
Ulusoy, A.1
Bjorklund, T.2
Hermening, S.3
Kirik, D.4
-
24
-
-
0036679197
-
{alpha}-Synucleinopathy and selective dopaminergic neuron loss in a rat lentiviral-based model of Parkinson's disease
-
Lo Bianco C, Ridet JL, Schneider BL, Deglon N, Aebischer P. {alpha}-Synucleinopathy and selective dopaminergic neuron loss in a rat lentiviral-based model of Parkinson's disease. Proc Natl Acad Sci USA 2002; 99: 10813-10818.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 10813-10818
-
-
Lo Bianco, C.1
Ridet, J.L.2
Schneider, B.L.3
Deglon, N.4
Aebischer, P.5
-
25
-
-
10644281090
-
Lentiviral vector delivery of parkin prevents dopaminergic degeneration in an α-synuclein rat model of Parkinson's disease
-
DOI 10.1073/pnas.0405313101
-
Lo Bianco C, Schneider BL, Bauer M, Sajadi A, Brice A, Iwatsubo T et al. Lentiviral vector delivery of parkin prevents dopaminergic degeneration in an alpha-synuclein rat model of Parkinson's disease. Proc Natl Acad Sci USA 2004; 101: 17510-17515. (Pubitemid 39657434)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.50
, pp. 17510-17515
-
-
Lo Bianco, C.1
Schneider, B.L.2
Bauer, M.3
Sajadi, A.4
Brice, A.5
Iwatsubo, T.6
Aebischer, P.7
-
26
-
-
47049084912
-
Viral vectors, animal models and new therapies for Parkinson's disease
-
Schneider B, Zufferey R, Aebischer P. Viral vectors, animal models and new therapies for Parkinson's disease. Parkinsonism Relat Disord 2008; 14(Suppl 2): S169-S171.
-
(2008)
Parkinsonism Relat Disord
, vol.14
, Issue.SUPPL. 2
-
-
Schneider, B.1
Zufferey, R.2
Aebischer, P.3
-
27
-
-
2942689239
-
Transduction profiles of recombinant adeno-associated virus vectors derived from serotypes 2 and 5 in the nigrostriatal system of rats
-
DOI 10.1128/JVI.78.13.6808-6817.2004
-
Paterna JC, Feldon J, Bueler H. Transduction profiles of recombinant adeno-associated virus vectors derived from serotypes 2 and 5 in the nigrostriatal system of rats. J Virol 2004; 78: 6808-6817. (Pubitemid 38781518)
-
(2004)
Journal of Virology
, vol.78
, Issue.13
, pp. 6808-6817
-
-
Paterna, J.-C.1
Feldon, J.2
Bueler, H.3
-
28
-
-
4344566457
-
Recombinant AAV viral vectors pseudotyped with viral capsids from serotypes 1, 2, and 5 display differential efficiency and cell tropism after delivery to different regions of the central nervous system
-
DOI 10.1016/j.ymthe.2004.05.024, PII S1525001604001911
-
Burger C, Gorbatyuk OS, Velardo MJ, Peden CS, Williams P, Zolotukhin S et al. Recombinant AAV viral vectors pseudotyped with viral capsids from serotypes 1, 2, and 5 display differential efficiency and cell tropism after delivery to different regions of the central nervous system. Mol Ther 2004; 10: 302-317. (Pubitemid 39117875)
-
(2004)
Molecular Therapy
, vol.10
, Issue.2
, pp. 302-317
-
-
Burger, C.1
Gorbatyuk, O.S.2
Velardo, M.J.3
Peden, C.S.4
Williams, P.5
Zolotukhin, S.6
Reier, P.J.7
Mandel, R.J.8
Muzyczka, N.9
-
29
-
-
34247271439
-
Comparative analysis of adeno-associated viral vector serotypes 1, 2, 5, 7, and 8 in mouse brain
-
DOI 10.1089/hum.2006.178
-
Taymans JM, Vandenberghe LH, Haute CV, Thiry I, Deroose CM, Mortelmans L et al. Comparative analysis of adeno-associated viral vector serotypes 1, 2, 5, 7, and 8 in mouse brain. Hum Gene Ther 2007; 18: 195-206. (Pubitemid 46626459)
-
(2007)
Human Gene Therapy
, vol.18
, Issue.3
, pp. 195-206
-
-
Taymans, J.-M.1
Vandenberghe, L.H.2
Van Den Haute, C.3
Thiry, I.4
Deroose, C.M.5
Mortelmans, L.6
Wilson, J.M.7
Debyser, Z.8
Baekelandt, V.9
-
30
-
-
64149106830
-
Comparison of transduction efficiency of recombinant AAV serotypes 1, 2, 5, and 8 in the rat nigrostriatal system
-
McFarland NR, Lee JS, Hyman BT, McLean PJ. Comparison of transduction efficiency of recombinant AAV serotypes 1, 2, 5, and 8 in the rat nigrostriatal system. J Neurochem 2009; 109: 838-845.
-
(2009)
J Neurochem
, vol.109
, pp. 838-845
-
-
McFarland, N.R.1
Lee, J.S.2
Hyman, B.T.3
McLean, P.J.4
-
31
-
-
77649270699
-
Differential transduction following basal ganglia administration of distinct pseudotyped AAV capsid serotypes in nonhuman primates
-
Dodiya HB, Bjorklund T, Stansell III J, Mandel RJ, Kirik D, Kordower JH. Differential transduction following basal ganglia administration of distinct pseudotyped AAV capsid serotypes in nonhuman primates. Mol Ther 2009; 18: 579-587.
-
(2009)
Mol Ther
, vol.18
, pp. 579-587
-
-
Dodiya, H.B.1
Bjorklund, T.2
Stansell Iii, J.3
Mandel, R.J.4
Kirik, D.5
Kordower, J.H.6
-
32
-
-
72249104303
-
Adeno-associated viral vector (AAV)-mediated gene transfer in the red nucleus of the adult rat brain: Comparative analysis of the transduction properties of seven AAV serotypes and lentiviral vectors
-
Blits B, Derks S, Twisk J, Ehlert E, Prins J, Verhaagen J. Adeno-associated viral vector (AAV)-mediated gene transfer in the red nucleus of the adult rat brain: comparative analysis of the transduction properties of seven AAV serotypes and lentiviral vectors. J Neurosci Methods 2009; 185: 257-263.
-
(2009)
J Neurosci Methods
, vol.185
, pp. 257-263
-
-
Blits, B.1
Derks, S.2
Twisk, J.3
Ehlert, E.4
Prins, J.5
Verhaagen, J.6
-
33
-
-
0034724209
-
Recombinant adeno-associated virus type 2, 4, and 5 vectors: Transduction of variant cell types and regions in the mammalian central nervous system
-
DOI 10.1073/pnas.050581197
-
Davidson BL, Stein CS, Heth JA, Martins I, Kotin RM, Derksen TA et al. Recombinant adeno-associated virus type 2, 4, and 5 vectors: transduction of variant cell types and regions in the mammalian central nervous system. Proc Natl Acad Sci USA 2000; 97: 3428-3432. (Pubitemid 30183319)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.7
, pp. 3428-3432
-
-
Davidson, B.L.1
Stein, C.S.2
Heth, J.A.3
Martins, I.4
Kotin, R.M.5
Derksen, T.A.6
Zabner, J.7
Ghodsi, A.8
Chiorini, J.A.9
-
34
-
-
1542529998
-
Gene delivery to the mouse brain with adeno-associated virus
-
Passini MA, Watson DJ, Wolfe JH. Gene delivery to the mouse brain with adeno-associated virus. Methods Mol Biol 2004; 246: 225-236.
-
(2004)
Methods Mol Biol
, vol.246
, pp. 225-236
-
-
Passini, M.A.1
Watson, D.J.2
Wolfe, J.H.3
-
35
-
-
0037015049
-
Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy
-
DOI 10.1073/pnas.182412299
-
Gao GP, Alvira MR, Wang L, Calcedo R, Johnston J, Wilson JM. Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy. Proc Natl Acad Sci USA 2002; 99: 11854-11859. (Pubitemid 34994488)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.18
, pp. 11854-11859
-
-
Gao, G.-P.1
Alvira, M.R.2
Wang, L.3
Calcedo, R.4
Johnston, J.5
Wilson, J.M.6
-
36
-
-
2642512201
-
Clades of adeno-associated viruses are widely disseminated in human tissues
-
DOI 10.1128/JVI.78.12.6381-6388.2004
-
Gao G, Vandenberghe LH, Alvira MR, Lu Y, Calcedo R, Zhou X et al. Clades of Adeno-associated viruses are widely disseminated in human tissues. J Virol 2004; 78: 6381-6388. (Pubitemid 38715936)
-
(2004)
Journal of Virology
, vol.78
, Issue.12
, pp. 6381-6388
-
-
Gao, G.1
Vandenberghe, L.H.2
Alvira, M.R.3
Lu, Y.4
Calcedo, R.5
Zhou, X.6
Wilson, J.M.7
-
37
-
-
73849120718
-
Naturally occurring singleton residues in AAV capsid impact vector performance and illustrate structural constraints
-
Vandenberghe LH, Breous E, Nam HJ, Gao G, Xiao R, Sandhu A et al. Naturally occurring singleton residues in AAV capsid impact vector performance and illustrate structural constraints. Gene Therapy 2009; 16: 1416-1428.
-
(2009)
Gene Therapy
, vol.16
, pp. 1416-1428
-
-
Vandenberghe, L.H.1
Breous, E.2
Nam, H.J.3
Gao, G.4
Xiao, R.5
Sandhu, A.6
-
39
-
-
0036428796
-
Promoters and regulatory elements that improve adeno-associated virus transgene expression in the brain
-
DOI 10.1016/S1046-2023(02)00227-X, PII S104620230200227X
-
Fitzsimons HL, Bland RJ, During MJ. Promoters and regulatory elements that improve adeno-associated virus transgene expression in the brain. Methods 2002; 28: 227-236. (Pubitemid 35341086)
-
(2002)
Methods
, vol.28
, Issue.2
, pp. 227-236
-
-
Fitzsimons, H.L.1
Bland, R.J.2
During, M.J.3
-
40
-
-
77958083331
-
Efficient serotype-dependent release of functional vector into the culture medium during adeno-associated virus manufacturing
-
Vandenberghe LH, Xiao R, Lock M, Lin J, Korn M, Wilson JM. Efficient serotype-dependent release of functional vector into the culture medium during adeno-associated virus manufacturing. Hum Gene Ther 2010; 21: 1251-1257.
-
(2010)
Hum Gene Ther
, vol.21
, pp. 1251-1257
-
-
Vandenberghe, L.H.1
Xiao, R.2
Lock, M.3
Lin, J.4
Korn, M.5
Wilson, J.M.6
-
41
-
-
79955941085
-
-
submitted
-
Toelen J, VdP A, Carlon M, Michiels M, Lock M, Vandenberghe L et al. Gene Therapy submitted.
-
Gene Therapy
-
-
Toelen, J.1
Vdp, A.2
Carlon, M.3
Michiels, M.4
Lock, M.5
Vandenberghe, L.6
-
42
-
-
77958104835
-
Rapid, simple, and versatile manufacturing of recombinant adeno-associated viral vectors at scale
-
Lock M, Alvira M, Vandenberghe LH, Samanta A, Toelen J, Debyser Z et al. Rapid, simple, and versatile manufacturing of recombinant adeno-associated viral vectors at scale. Hum Gene Ther 2010; 21: 1259-1271.
-
(2010)
Hum Gene Ther
, vol.21
, pp. 1259-1271
-
-
Lock, M.1
Alvira, M.2
Vandenberghe, L.H.3
Samanta, A.4
Toelen, J.5
Debyser, Z.6
-
43
-
-
0035151061
-
Neuron-specific expression of therapeutic proteins: Evaluation of different cellular promoters in recombinant adenoviral vectors
-
DOI 10.1006/mcne.2000.0929
-
Kugler S, Meyn L, Holzmuller H, Gerhardt E, Isenmann S, Schulz JB et al. Neuron-specific expression of therapeutic proteins: evaluation of different cellular promoters in recombinant adenoviral vectors. Mol Cell Neurosci 2001; 17: 78-96. (Pubitemid 32113540)
-
(2001)
Molecular and Cellular Neuroscience
, vol.17
, Issue.1
, pp. 78-96
-
-
Kugler, S.1
Meyn, L.2
Holzmuller, H.3
Gerhardt, E.4
Isenmann, S.5
Schulz, J.B.6
Bahr, M.7
-
44
-
-
0030062098
-
Neuron-specific gene expression of synapsin I: Major role of a negative regulatory mechanism
-
DOI 10.1074/jbc.271.6.3317
-
Schoch S, Cibelli G, Thiel G. Neuron-specific gene expression of synapsin I. Major role of a negative regulatory mechanism. J Biol Chem 1996; 271: 3317-3323. (Pubitemid 26055638)
-
(1996)
Journal of Biological Chemistry
, vol.271
, Issue.6
, pp. 3317-3323
-
-
Schoch, S.1
Cibelli, G.2
Thiel, G.3
-
45
-
-
1542369977
-
From virus evolution to vector revolution: Use of naturally occurring serotypes of adeno-associated virus (AAV) as novel vectors for human gene therapy
-
Grimm D, Kay MA. From virus evolution to vector revolution: use of naturally occurring serotypes of adeno-associated virus (AAV) as novel vectors for human gene therapy. Curr Gene Ther 2003; 3: 281-304.
-
(2003)
Curr Gene Ther
, vol.3
, pp. 281-304
-
-
Grimm, D.1
Kay, M.A.2
-
46
-
-
77950858020
-
High AAV vector purity results in serotype-and tissue-independent enhancement of transduction efficiency
-
Ayuso E, Mingozzi F, Montane J, Leon X, Anguela XM, Haurigot V et al. High AAV vector purity results in serotype-and tissue-independent enhancement of transduction efficiency. Gene Therapy 2009; 17: 503-510.
-
(2009)
Gene Therapy
, vol.17
, pp. 503-510
-
-
Ayuso, E.1
Mingozzi, F.2
Montane, J.3
Leon, X.4
Anguela, X.M.5
Haurigot, V.6
-
47
-
-
37549061385
-
AAV8, 9, Rh10, Rh43 vector gene transfer in the rat brain: Effects of serotype, promoter and purification method
-
Klein RL, Dayton RD, Tatom JB, Henderson KM, Henning PP. AAV8, 9, Rh10, Rh43 vector gene transfer in the rat brain: effects of serotype, promoter and purification method. Mol Ther 2008; 16: 89-96.
-
(2008)
Mol Ther
, vol.16
, pp. 89-96
-
-
Klein, R.L.1
Dayton, R.D.2
Tatom, J.B.3
Henderson, K.M.4
Henning, P.P.5
-
48
-
-
34547118339
-
Time course of transgene expression after intrastriatal pseudotyped rAAV2/1, rAAV2/2, rAAV2/5, and rAAV2/8 transduction in the rat
-
DOI 10.1038/sj.mt.6300227, PII 6300227
-
Reimsnider S, Manfredsson FP, Muzyczka N, Mandel RJ. Time course of transgene expression after intrastriatal pseudotyped rAAV2/1, rAAV2/2, rAAV2/5, and rAAV2/8 transduction in the rat. Mol Ther 2007; 15: 1504-1511. (Pubitemid 47103062)
-
(2007)
Molecular Therapy
, vol.15
, Issue.8
, pp. 1504-1511
-
-
Reimsnider, S.1
Manfredsson, F.P.2
Muzyczka, N.3
Mandel, R.J.4
-
49
-
-
77649271981
-
Comparative transduction efficiency of AAV vector serotypes 1-6 in the substantia nigra and striatum of the primate brain
-
Markakis EA, Vives KP, Bober J, Leichtle S, Leranth C, Beecham J et al. Comparative transduction efficiency of AAV vector serotypes 1-6 in the substantia nigra and striatum of the primate brain. Mol Ther 2010; 18: 588-593.
-
(2010)
Mol Ther
, vol.18
, pp. 588-593
-
-
Markakis, E.A.1
Vives, K.P.2
Bober, J.3
Leichtle, S.4
Leranth, C.5
Beecham, J.6
-
50
-
-
77649272865
-
Dual reporter comparative indexing of rAAV pseudotyped vectors in chimpanzee airway
-
Flotte TR, Fischer AC, Goetzmann J, Mueller C, Cebotaru L, Yan Z et al. Dual reporter comparative indexing of rAAV pseudotyped vectors in chimpanzee airway. Mol Ther 2010; 18: 594-600.
-
(2010)
Mol Ther
, vol.18
, pp. 594-600
-
-
Flotte, T.R.1
Fischer, A.C.2
Goetzmann, J.3
Mueller, C.4
Cebotaru, L.5
Yan, Z.6
-
51
-
-
0030010409
-
Inactivation of the very strong HCMV immediate early promoter by DNA CpG methylation in vitro
-
Prosch S, Stein J, Staak K, Liebenthal C, Volk HD, Kruger DH. Inactivation of the very strong HCMV immediate early promoter by DNA CpG methylation in vitro. Biol Chem Hoppe Seyler 1996; 377: 195-201.
-
(1996)
Biol Chem Hoppe Seyler
, vol.377
, pp. 195-201
-
-
Prosch, S.1
Stein, J.2
Staak, K.3
Liebenthal, C.4
Volk, H.D.5
Kruger, D.H.6
-
52
-
-
21244460769
-
New recombinant serotypes of AAV vectors
-
DOI 10.2174/1566523054065057
-
Gao G, Vandenberghe LH, Wilson JM. New recombinant serotypes of AAV vectors. Curr Gene Ther 2005; 5: 285-297. (Pubitemid 40895013)
-
(2005)
Current Gene Therapy
, vol.5
, Issue.3
, pp. 285-297
-
-
Gao, G.1
Vandenberghe, L.H.2
Wilson, J.M.3
-
53
-
-
68949216338
-
Highly efficient multicistronic lentiviral vectors with peptide 2A sequences
-
Ibrahimi A, Vande Velde G, Reumers V, Toelen J, Thiry I, Vandeputte C et al. Highly efficient multicistronic lentiviral vectors with peptide 2A sequences. Hum Gene Ther 2009; 20: 845-860.
-
(2009)
Hum Gene Ther
, vol.20
, pp. 845-860
-
-
Ibrahimi, A.1
Vande Velde, G.2
Reumers, V.3
Toelen, J.4
Thiry, I.5
Vandeputte, C.6
-
54
-
-
33746883603
-
Noninvasive Monitoring of Long-Term Lentiviral Vector-Mediated Gene Expression in Rodent Brain with Bioluminescence Imaging
-
DOI 10.1016/j.ymthe.2006.05.007, PII S1525001606001821
-
Deroose CM, Reumers V, Gijsbers R, Bormans G, Debyser Z, Mortelmans L et al. Noninvasive monitoring of long-term lentiviral vector-mediated gene expression in rodent brain with bioluminescence imaging. Mol Ther 2006; 14: 423-431. (Pubitemid 44184969)
-
(2006)
Molecular Therapy
, vol.14
, Issue.3
, pp. 423-431
-
-
Deroose, C.M.1
Reumers, V.2
Gijsbers, R.3
Bormans, G.4
Debyser, Z.5
Mortelmans, L.6
Baekelandt, V.7
-
55
-
-
0036247444
-
Characterization of lentiviral vector-mediated gene transfer in adult mouse brain
-
DOI 10.1089/10430340252899019
-
Baekelandt V, Claeys A, Eggermont K, Lauwers E, De Strooper B, Nuttin B et al. Characterization of lentiviral vector-mediated gene transfer in adult mouse brain. Hum Gene Ther 2002; 13: 841-853. (Pubitemid 34493977)
-
(2002)
Human Gene Therapy
, vol.13
, Issue.7
, pp. 841-853
-
-
Baekelandt, V.1
Claeys, A.2
Eggermont, K.3
Lauwers, E.4
De Strooper, B.5
Nuttin, B.6
Debyser, Z.7
-
56
-
-
11844300345
-
Design-based stereology in neuroscience
-
DOI 10.1016/j.neuroscience.2004.08.050, PII S0306452204008516
-
Schmitz C, Hof PR. Design-based stereology in neuroscience. Neuroscience 2005; 130: 813-831. (Pubitemid 40094616)
-
(2005)
Neuroscience
, vol.130
, Issue.4
, pp. 813-831
-
-
Schmitz, C.1
Hof, P.R.2
|