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Volumn 11, Issue 3, 2011, Pages 211-217

Perivascular adipose tissue and its role in type 2 diabetes and cardiovascular disease

Author keywords

Endothelium; Insulin resistance; Intracellular signaling; Obesity

Indexed keywords

ADIPOCYTOKINE; ADIPONECTIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; LEPTIN; MONOCYTE CHEMOTACTIC PROTEIN 1; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA;

EID: 79955920129     PISSN: 15344827     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11892-011-0186-y     Document Type: Review
Times cited : (78)

References (50)
  • 2
    • 70349578367 scopus 로고    scopus 로고
    • Obesity promotes inflammation in periaortic adipose tissue and angiotensin II-induced abdominal aortic aneurysm formation
    • Police SB, Thatcher SE, Charnigo R, Daugherty A, Cassis LA. Obesity promotes inflammation in periaortic adipose tissue and angiotensin II-induced abdominal aortic aneurysm formation. Arterioscler Thromb Vasc Biol. 2009;29(10):1458-64.
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , Issue.10 , pp. 1458-1464
    • Police, S.B.1    Thatcher, S.E.2    Charnigo, R.3    Daugherty, A.4    Cassis, L.A.5
  • 3
    • 4444224867 scopus 로고    scopus 로고
    • Visceral periadventitial adipose tissue regulates arterial tone of mesenteric arteries
    • DOI 10.1161/01.HYP.0000140058.28994.ec
    • Verlohren S, Dubrovska G, Tsang SY, Essin K, Luft FC, Huang Y, et al. Visceral periadventitial adipose tissue regulates arterial tone of mesenteric arteries. Hypertension. 2004;44(3):271-6. (Pubitemid 39167221)
    • (2004) Hypertension , vol.44 , Issue.3 , pp. 271-276
    • Verlohren, S.1    Dubrovska, G.2    Tsang, S.-Y.3    Essin, K.4    Luft, F.C.5    Huang, Y.6    Gollasch, M.7
  • 4
    • 19744362790 scopus 로고    scopus 로고
    • "Vasocrine" signalling from perivascular fat: A mechanism linking insulin resistance to vascular disease
    • Yudkin JS, Eringa E, Stehouwer CD. "Vasocrine" signalling from perivascular fat: a mechanism linking insulin resistance to vascular disease. Lancet. 2005;365(9473):1817-20.
    • (2005) Lancet , vol.365 , Issue.9473 , pp. 1817-1820
    • Yudkin, J.S.1    Eringa, E.2    Stehouwer, C.D.3
  • 6
    • 65249102725 scopus 로고    scopus 로고
    • Local inflammation and hypoxia abolish the protective anticontractile properties of perivascular fat in obese patients
    • In this article, it is shown for the first time that adiponectin from human PAT surrounding resistance arteries increases NO bioavailability. In subjects with metabolic syndrome, this effect on vasodilation is blunted
    • Greenstein AS, Khavandi K, Withers SB, Sonoyama K, Clancy O, Jeziorska M, et al. Local inflammation and hypoxia abolish the protective anticontractile properties of perivascular fat in obese patients. Circulation. 2009;119(12):1661-70. In this article, it is shown for the first time that adiponectin from human PAT surrounding resistance arteries increases NO bioavailability. In subjects with metabolic syndrome, this effect on vasodilation is blunted.
    • (2009) Circulation , vol.119 , Issue.12 , pp. 1661-1670
    • Greenstein, A.S.1    Khavandi, K.2    Withers, S.B.3    Sonoyama, K.4    Clancy, O.5    Jeziorska, M.6
  • 7
    • 85047694430 scopus 로고    scopus 로고
    • Abundant progenitor cells in the adventitia contribute to atheroscleroses of vein grafts in ApoE-deficient mice
    • DOI 10.1172/JCI200419628
    • Hu Y, Zhang Z, Torsney E, Afzal AR, Davison F, Metzler B, et al. Abundant progenitor cells in the adventitia contribute to atherosclerosis of vein grafts in ApoE-deficient mice. J Clin Invest. 2004;113(9):1258-65. (Pubitemid 39069924)
    • (2004) Journal of Clinical Investigation , vol.113 , Issue.9 , pp. 1258-1265
    • Hu, Y.1    Zhang, Z.2    Torsney, E.3    Afzal, A.R.4    Davison, F.5    Metzler, B.6    Xu, Q.7
  • 8
    • 0018672096 scopus 로고
    • Ultrastructural features of mast cells in human omental veins
    • Thureson-Klein A, Stijarne L. Ultrastructural features of mast cells in human omental veins. Blood Vessels. 1979;16(6):311-9. (Pubitemid 10212284)
    • (1979) Blood Vessels , vol.16 , Issue.6 , pp. 311-319
    • Thureson-Klein, A.1    Stijarne, L.2
  • 10
    • 53549130485 scopus 로고    scopus 로고
    • White fat progenitor cells reside in the adipose vasculature
    • Tang W, Zeve D, Suh JM, Bosnakovski D, Kyba M, Hammer RE, et al. White fat progenitor cells reside in the adipose vasculature. Science. 2008;322(5901):583-6.
    • (2008) Science , vol.322 , Issue.5901 , pp. 583-586
    • Tang, W.1    Zeve, D.2    Suh, J.M.3    Bosnakovski, D.4    Kyba, M.5    Hammer, R.E.6
  • 12
    • 53549086389 scopus 로고    scopus 로고
    • Perivascular fatty tissue at the brachial artery is linked to insulin resistance but not to local endothelial dysfunction
    • This article shows that the amount of PAT around the brachial artery correlates with wholebody insulin sensitivity; this correlation is independent from the amount of visceral adipose tissue
    • Rittig K, Staib K, Machann J, Bottcher M, Peter A, Schick F, et al. Perivascular fatty tissue at the brachial artery is linked to insulin resistance but not to local endothelial dysfunction. Diabetologia 2008;51(11):2093-9. This article shows that the amount of PAT around the brachial artery correlates with wholebody insulin sensitivity; this correlation is independent from the amount of visceral adipose tissue.
    • (2008) Diabetologia , vol.51 , Issue.11 , pp. 2093-2099
    • Rittig, K.1    Staib, K.2    Machann, J.3    Bottcher, M.4    Peter, A.5    Schick, F.6
  • 14
    • 0036318227 scopus 로고    scopus 로고
    • Mice lacking paternally expressed Pref-1/Dlk1 display growth retardation and accelerated adiposity
    • DOI 10.1128/MCB.22.15.5585-5592.2002
    • Moon YS, Smas CM, Lee K, Villena JA, Kim KH, Yun EJ, et al. Mice lacking paternally expressed Pref-1/Dlk1 display growth retardation and accelerated adiposity. Mol Cell Biol. 2002;22 (15):5585-92. (Pubitemid 34755767)
    • (2002) Molecular and Cellular Biology , vol.22 , Issue.15 , pp. 5585-5592
    • Moon, Y.S.1    Smas, C.M.2    Lee, K.3    Villena, J.A.4    Kim, K.-H.5    Yun, E.J.6    Sul, H.S.7
  • 15
    • 68349160704 scopus 로고    scopus 로고
    • Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice
    • Liu J, Divoux A, Sun J, Zhang J, Clement K, Glickman JN, et al. Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice. Nat Med. 2009;15(8):940-5.
    • (2009) Nat Med , vol.15 , Issue.8 , pp. 940-945
    • Liu, J.1    Divoux, A.2    Sun, J.3    Zhang, J.4    Clement, K.5    Glickman, J.N.6
  • 17
    • 34447516158 scopus 로고    scopus 로고
    • Activated human T lymphocytes express cyclooxygenase-2 and produce proadipogenic prostaglandins that drive human orbital fibroblast differentiation to adipocytes
    • DOI 10.2353/ajpath.2006.060434
    • Feldon SE, O'Loughlin CW, Ray DM, Landskroner-Eiger S, Seweryniak KE, Phipps RP. Activated human T lymphocytes express cyclooxygenase-2 and produce proadipogenic prostaglandins that drive human orbital fibroblast differentiation to adipocytes. Am J Pathol. 2006;169(4):1183-93. (Pubitemid 351194355)
    • (2006) American Journal of Pathology , vol.169 , Issue.4 , pp. 1183-1193
    • Feldon, S.E.1    O'Loughlin, C.W.2    Ray, D.M.3    Landskroner-Eiger, S.4    Seweryniak, K.E.5    Phipps, R.P.6
  • 18
    • 44949085653 scopus 로고    scopus 로고
    • Adventitialmast cells contribute to pathogenesis in the progression of abdominal aortic aneurysm
    • Tsuruda T, Kato J, Hatakeyama K, Kojima K, YanoM, Yano Y, et al. Adventitialmast cells contribute to pathogenesis in the progression of abdominal aortic aneurysm. Circ Res. 2008;102(11):1368-77.
    • (2008) Circ Res , vol.102 , Issue.11 , pp. 1368-1377
    • Tsuruda, T.1    Kato, J.2    Hatakeyama, K.3    Kojima, K.4    Yano, M.5    Yano, Y.6
  • 19
    • 61949318555 scopus 로고    scopus 로고
    • Proinflammatory phenotype of perivascular adipocytes: Influence of high-fat feeding
    • The authors show that PAT exhibits an increased proinflamma tory response after 2 weeks of high-fat diet; this response is stronger in PAT than in other adipose tissue depots. Therefore, PAT can be considered a distinctive depot of adipose tissue
    • Chatterjee TK, Stoll LL, Denning GM, Harrelson A, Blomkalns AL, Idelman G, et al. Proinflammatory phenotype of perivascular adipocytes: influence of high-fat feeding. Circ Res 2009;104(4):541-9. The authors show that PAT exhibits an increased proinflamma tory response after 2 weeks of high-fat diet; this response is stronger in PAT than in other adipose tissue depots. Therefore, PAT can be considered a distinctive depot of adipose tissue.
    • (2009) Circ Res , vol.104 , Issue.4 , pp. 541-549
    • Chatterjee, T.K.1    Stoll, L.L.2    Denning, G.M.3    Harrelson, A.4    Blomkalns, A.L.5    Idelman, G.6
  • 20
    • 33748992313 scopus 로고    scopus 로고
    • Adipocytokines: Mediators linking adipose tissue, inflammation and immunity
    • DOI 10.1038/nri1937, PII NRI1937
    • Tilg H, Moschen AR. Adipocytokines: mediators linking adipose tissue, inflammation and immunity. Nat Rev Immunol. 2006;6(10):772-83. (Pubitemid 44453463)
    • (2006) Nature Reviews Immunology , vol.6 , Issue.10 , pp. 772-783
    • Tilg, H.1    Moschen, A.R.2
  • 21
    • 33748933358 scopus 로고    scopus 로고
    • Serum Concentrations of Adiponectin and Risk of Type 2 Diabetes Mellitus and Coronary Heart Disease in Apparently Healthy Middle-Aged Men. Results From the 18-Year Follow-Up of a Large Cohort From Southern Germany
    • DOI 10.1016/j.jacc.2006.06.053, PII S0735109706018341
    • Koenig W, Khuseyinova N, Baumert J, Meisinger C, Lowel H. Serum concentrations of adiponectin and risk of type 2 diabetes mellitus and coronary heart disease in apparently healthy middle-aged men: results from the 18-year follow-up of a large cohort from southern Germany. J Am Coll Cardiol. 2006;48(7):1369-77. (Pubitemid 44436825)
    • (2006) Journal of the American College of Cardiology , vol.48 , Issue.7 , pp. 1369-1377
    • Koenig, W.1    Khuseyinova, N.2    Baumert, J.3    Meisinger, C.4    Lowel, H.5
  • 22
    • 4344665855 scopus 로고    scopus 로고
    • Adiponectin and the development of type 2 diabetes: The atherosclerosis risk in communities study
    • DOI 10.2337/diabetes.53.9.2473
    • Duncan BB, Schmidt MI, Pankow JS, Bang H, Couper D, Ballantyne CM, et al. Adiponectin and the development of type 2 diabetes: the atherosclerosis risk in communities study. Diabetes. 2004;53(9):2473-8. (Pubitemid 39145606)
    • (2004) Diabetes , vol.53 , Issue.9 , pp. 2473-2478
    • Duncan, B.B.1    Schmidt, M.I.2    Pankow, J.S.3    Bang, H.4    Couper, D.5    Ballantyne, C.M.6    Hoogeveen, R.C.7    Heiss, G.8
  • 23
    • 77951184667 scopus 로고    scopus 로고
    • Macrophage adiponectin expression improves insulin sensitivity and protects against inflammation and atherosclerosis
    • Luo N, Liu J, Chung BH, Yang Q, Klein RL, Garvey WT, et al. Macrophage adiponectin expression improves insulin sensitivity and protects against inflammation and atherosclerosis. Diabetes. 2010;59(4):791-9.
    • (2010) Diabetes , vol.59 , Issue.4 , pp. 791-799
    • Luo, N.1    Liu, J.2    Chung, B.H.3    Yang, Q.4    Klein, R.L.5    Garvey, W.T.6
  • 24
    • 33646506876 scopus 로고    scopus 로고
    • Adiponectin produced in coronary circulation regulates coronary flow reserve in nondiabetic patients with angiographically normal coronary arteries
    • Date H, Imamura T, Ideguchi T, Kawagoe J, Sumi T, Masuyama H, et al. Adiponectin produced in coronary circulation regulates coronary flow reserve in nondiabetic patients with angiographically normal coronary arteries. Clin Cardiol. 2006;29(5):211-4.
    • (2006) Clin Cardiol , vol.29 , Issue.5 , pp. 211-214
    • Date, H.1    Imamura, T.2    Ideguchi, T.3    Kawagoe, J.4    Sumi, T.5    Masuyama, H.6
  • 25
    • 14644431030 scopus 로고    scopus 로고
    • Adiponectin expression in human epicardial adipose tissue in vivo is lower in patients with coronary artery disease
    • DOI 10.1016/j.cyto.2004.11.002
    • Iacobellis G, Pistilli D, Gucciardo M, Leonetti F, Miraldi F, Brancaccio G, et al. Adiponectin expression in human epicardial adipose tissue in vivo is lower in patients with coronary artery disease. Cytokine. 2005;29(6):251-5. (Pubitemid 40320925)
    • (2005) Cytokine , vol.29 , Issue.6 , pp. 251-255
    • Iacobellis, G.1    Pistilli, D.2    Gucciardo, M.3    Leonetti, F.4    Miraldi, F.5    Brancaccio, G.6    Gallo, P.7    Tiziana, D.G.C.R.8
  • 27
    • 0028139089 scopus 로고
    • Positional cloning of the mouse obese gene and its human homologue
    • DOI 10.1038/372425a0
    • Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM. Positional cloning of the mouse obese gene and its human homologue. Nature. 1994;372(6505):425-32. (Pubitemid 24365442)
    • (1994) Nature , vol.372 , Issue.6505 , pp. 425-432
    • Zhang, Y.1    Proenca, R.2    Maffei, M.3    Barone, M.4    Leopold, L.5    Friedman, J.M.6
  • 28
    • 0036897102 scopus 로고    scopus 로고
    • Insulin-mediated hemodynamic changes are impaired in muscle of Zucker obese rats
    • Wallis MG, Wheatley CM, Rattigan S, Barrett EJ, Clark ADH, Clark MG. Insulin-mediated hemodynamic changes are impaired in muscle of zucker obese rats. Diabetes. 2002;51(12):3492-8. (Pubitemid 35403455)
    • (2002) Diabetes , vol.51 , Issue.12 , pp. 3492-3498
    • Wallis, M.G.1    Wheatley, C.M.2    Rattigan, S.3    Barrett, E.J.4    Clark, A.D.H.5    Clark, M.G.6
  • 30
    • 77955981037 scopus 로고    scopus 로고
    • Epicardial perivascular adipose-derived leptin exacerbates coronary endothelial dysfunction in metabolic syndrome via a protein kinase C-beta pathway
    • Payne GA, Borbouse L, Kumar S, Neeb Z, Alloosh M, Sturek M, et al. Epicardial perivascular adipose-derived leptin exacerbates coronary endothelial dysfunction in metabolic syndrome via a protein kinase C-beta pathway. Arterioscler Thromb Vasc Biol. 2010;30(9):1711-7.
    • (2010) Arterioscler Thromb Vasc Biol , vol.30 , Issue.9 , pp. 1711-1717
    • Payne, G.A.1    Borbouse, L.2    Kumar, S.3    Neeb, Z.4    Alloosh, M.5    Sturek, M.6
  • 34
    • 67649663972 scopus 로고    scopus 로고
    • Endothelium-dependent relaxation factor released by perivascular adipose tissue
    • Lee RM, Lu C, Su LY, Gao YJ. Endothelium-dependent relaxation factor released by perivascular adipose tissue. J Hypertens. 2009;27(4):782-90.
    • (2009) J Hypertens , vol.27 , Issue.4 , pp. 782-790
    • Lee, R.M.1    Lu, C.2    Su, L.Y.3    Gao, Y.J.4
  • 36
    • 73349097268 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase uncoupling and perivascular adipose oxidative stress and inflammation contribute to vascular dysfunction in a rodent model of metabolic syndrome
    • Marchesi C, Ebrahimian T, Angulo O, Paradis P, Schiffrin EL. Endothelial nitric oxide synthase uncoupling and perivascular adipose oxidative stress and inflammation contribute to vascular dysfunction in a rodent model of metabolic syndrome. Hypertension. 2009;54(6):1384-92.
    • (2009) Hypertension , vol.54 , Issue.6 , pp. 1384-1392
    • Marchesi, C.1    Ebrahimian, T.2    Angulo, O.3    Paradis, P.4    Schiffrin, E.L.5
  • 37
    • 56049106597 scopus 로고    scopus 로고
    • Impaired microvascular perfusion: A consequence of vascular dysfunction and a potential cause of insulin resistance in muscle
    • Clark MG. Impaired microvascular perfusion: a consequence of vascular dysfunction and a potential cause of insulin resistance in muscle. Am J Physiol Endocrinol Metab. 2008;295(4):E732-50.
    • (2008) Am J Physiol Endocrinol Metab , vol.295 , Issue.4
    • Clark, M.G.1
  • 38
    • 57749177096 scopus 로고    scopus 로고
    • Endothelial dysfunction and diabetes: Roles of hyperglycemia, impaired insulin signaling and obesity
    • Bakker W, Eringa EC, Sipkema P, van Hinsberg VW. Endothelial dysfunction and diabetes: roles of hyperglycemia, impaired insulin signaling and obesity. Cell Tissue Res. 2009;335(1):165-89.
    • (2009) Cell Tissue Res , vol.335 , Issue.1 , pp. 165-189
    • Bakker, W.1    Eringa, E.C.2    Sipkema, P.3    Van Hinsberg, V.W.4
  • 39
    • 33644857995 scopus 로고    scopus 로고
    • Physiological concentrations of insulin induce endothelin-dependent vasoconstriction of skeletal muscle resistance arteries in the presence of tumor necrosis factor-alpha dependence on c-Jun N-terminal kinase
    • DOI 10.1161/01.ATV.0000198248.19391.3e, PII 0004360520060200000012
    • Eringa EC, Stehouwer CD, Walburg K, Clark AD, van Nieuw Amerongen GP, Westerhof N, et al. Physiological concentrations of insulin induce endothelin-dependent vasoconstriction of skeletal muscle resistance arteries in the presence of tumor necrosis factor-alpha dependence on c-Jun N-terminal kinase. Arterioscler Thromb Vasc Biol. 2006;26(2):274-80. (Pubitemid 43732187)
    • (2006) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.26 , Issue.2 , pp. 274-280
    • Eringa, E.C.1    Stehouwer, C.D.A.2    Walburg, K.3    Clark, A.D.4    Van Nieuw, A.G.P.5    Westerhof, N.6    Sipkema, P.7
  • 42
    • 77954588212 scopus 로고    scopus 로고
    • Adaptative nitric oxide overproduction in perivascular adipose tissue during early diet-induced obesity
    • Gil-Ortega M, Stucchi P, Guzman-Ruiz R, Cano V, Arribas S, Gonzalez MC, et al. Adaptative nitric oxide overproduction in perivascular adipose tissue during early diet-induced obesity. Endocrinology. 2010;151(7):3299-306.
    • (2010) Endocrinology , vol.151 , Issue.7 , pp. 3299-3306
    • Gil-Ortega, M.1    Stucchi, P.2    Guzman-Ruiz, R.3    Cano, V.4    Arribas, S.5    Gonzalez, M.C.6
  • 44
    • 58849085994 scopus 로고    scopus 로고
    • Effects of hyperglycemia on the modulation of vascular function by perivascular adipose tissue
    • Lee RM, Lu C, Su LY, Werstuck G, Gao YJ. Effects of hyperglycemia on the modulation of vascular function by perivascular adipose tissue. J Hypertens. 2009;27(1):118-31.
    • (2009) J Hypertens , vol.27 , Issue.1 , pp. 118-131
    • Lee, R.M.1    Lu, C.2    Su, L.Y.3    Werstuck, G.4    Gao, Y.J.5
  • 45
    • 34249709524 scopus 로고    scopus 로고
    • Modulation of vascular function by perivascular adipose tissue: The role of endothelium and hydrogen peroxide
    • DOI 10.1038/sj.bjp.0707228, PII 0707228
    • Gao YJ, Lu C, Su LY, Sharma AM, Lee RM. Modulation of vascular function by perivascular adipose tissue: the role of endothelium and hydrogen peroxide. Br J Pharmacol. 2007;151(3):323-31. (Pubitemid 46842669)
    • (2007) British Journal of Pharmacology , vol.151 , Issue.3 , pp. 323-331
    • Gao, Y.-J.1    Lu, C.2    Su, L.-Y.3    Sharma, A.M.4    Lee, R.M.K.W.5
  • 46
    • 33846456616 scopus 로고    scopus 로고
    • Elevated blood pressure in transgenic lipoatrophic mice and altered vascular function
    • Takemori K, Gao YJ, Ding L, Lu C, Su LY, An WS, et al. Elevated blood pressure in transgenic lipoatrophic mice and altered vascular function. Hypertension. 2007;49(2):365-72.
    • (2007) Hypertension , vol.49 , Issue.2 , pp. 365-372
    • Takemori, K.1    Gao, Y.J.2    Ding, L.3    Lu, C.4    Su, L.Y.5    An, W.S.6
  • 47
    • 66749103201 scopus 로고    scopus 로고
    • Intermuscular adipose tissue (IMAT): Association with other adipose tissue compartments and insulin sensitivity
    • Boettcher M, Machann J, Stefan N, Thamer C, Haring HU, Claussen CD, et al. Intermuscular adipose tissue (IMAT): association with other adipose tissue compartments and insulin sensitivity. J Magn Reson Imaging. 2009;29(6):1340-5.
    • (2009) J Magn Reson Imaging , vol.29 , Issue.6 , pp. 1340-1345
    • Boettcher, M.1    Machann, J.2    Stefan, N.3    Thamer, C.4    Haring, H.U.5    Claussen, C.D.6
  • 48
    • 0034107084 scopus 로고    scopus 로고
    • Thigh adipose tissue distribution is associated with insulin resistance in obesity and in type 2 diabetes mellitus
    • Goodpaster BH, Thaete FL, Kelley DE. Thigh adipose tissue distribution is associated with insulin resistance in obesity and in type 2 diabetes mellitus. Am J Clin Nutr. 2000;71(4):885-92. (Pubitemid 30176569)
    • (2000) American Journal of Clinical Nutrition , vol.71 , Issue.4 , pp. 885-892
    • Goodpaster, B.H.1    Thaete, F.L.2    Kelley, D.E.3
  • 49
    • 64149117276 scopus 로고    scopus 로고
    • The vascular actions of insulin control its delivery to muscle and regulate the rate-limiting step in skeletal muscle insulin action
    • Barrett EJ, Eggleston EM, Inyard AC, Wang H, Li G, Chai W, et al. The vascular actions of insulin control its delivery to muscle and regulate the rate-limiting step in skeletal muscle insulin action. Diabetologia. 2009;52(5):752-64.
    • (2009) Diabetologia , vol.52 , Issue.5 , pp. 752-764
    • Barrett, E.J.1    Eggleston, E.M.2    Inyard, A.C.3    Wang, H.4    Li, G.5    Chai, W.6
  • 50
    • 34447324638 scopus 로고    scopus 로고
    • Regulation of vascular function and insulin sensitivity by adipose tissue: Focus on perivascular adipose tissue
    • DOI 10.1080/10739680701303584, PII 779873905
    • Eringa EC, Bakker W, Smulders YM, Serne EH, Yudkin JS, Stehouwer CD. Regulation of vascular function and insulin sensitivity by adipose tissue: focus on perivascular adipose tissue. Microcirculation. 2007;14(4-5):389-402. (Pubitemid 47050030)
    • (2007) Microcirculation , vol.14 , Issue.4-5 , pp. 389-402
    • Eringa, E.C.1    Bakker, W.2    Smulders, Y.M.3    Serne, E.H.4    Yudkin, J.S.5    Stehouwer, C.D.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.