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Volumn 43, Issue 6, 2011, Pages 936-945

Identification of serines 201 and 209 as sites of Pax3 phosphorylation and the altered phosphorylation status of Pax3-FOXO1 during early myogenic differentiation

Author keywords

Alveolar rhabdomyosarcoma; Myogenesis; Pax3; Pax3 FOXO1; Phosphorylation

Indexed keywords

GLYCOGEN SYNTHASE KINASE 3BETA; SERINE; TRANSCRIPTION FACTOR FKHR; TRANSCRIPTION FACTOR PAX3;

EID: 79955893149     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biocel.2011.03.010     Document Type: Article
Times cited : (25)

References (28)
  • 1
    • 45549098078 scopus 로고    scopus 로고
    • Phosphorylation regulates transcriptional activity of PAX3/FKHR and reveals novel therapeutic possibilities
    • R. Amstutz, M. Wachtel, H. Troxler, P. Kleinert, M. Ebauer, and T. Haneke Phosphorylation regulates transcriptional activity of PAX3/FKHR and reveals novel therapeutic possibilities Cancer Res 68 2008 3767 3776
    • (2008) Cancer Res , vol.68 , pp. 3767-3776
    • Amstutz, R.1    Wachtel, M.2    Troxler, H.3    Kleinert, P.4    Ebauer, M.5    Haneke, T.6
  • 4
    • 34447523329 scopus 로고    scopus 로고
    • Regulation of Pax3 by Proteasomal Degradation of Monoubiquitinated Protein in Skeletal Muscle Progenitors
    • DOI 10.1016/j.cell.2007.05.044, PII S0092867407006836
    • S.C. Boutet, M.H. Disatnik, L.S. Chan, K. Iori, and T.A. Rando Regulation of Pax3 by proteasomal degradation of monoubiquitinated protein in skeletal muscle progenitors Cell 130 2007 349 362 (Pubitemid 47081135)
    • (2007) Cell , vol.130 , Issue.2 , pp. 349-362
    • Boutet, S.C.1    Disatnik, M.-H.2    Chan, L.S.3    Iori, K.4    Rando, T.A.5
  • 5
    • 0025998840 scopus 로고
    • Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates
    • W.J. Boyle, P. van der Geer, and T. Hunter Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates Methods Enzymol 201 1991 110 149
    • (1991) Methods Enzymol , vol.201 , pp. 110-149
    • Boyle, W.J.1    Van Der Geer, P.2    Hunter, T.3
  • 6
    • 37549039009 scopus 로고    scopus 로고
    • A temporal switch from notch to Wnt signaling in muscle stem cells is necessary for normal adult myogenesis
    • A.S. Brack, I.M. Conboy, M.J. Conboy, J. Shen, and T.A. Rando A temporal switch from notch to Wnt signaling in muscle stem cells is necessary for normal adult myogenesis Cell Stem Cell 2 2008 50 59
    • (2008) Cell Stem Cell , vol.2 , pp. 50-59
    • Brack, A.S.1    Conboy, I.M.2    Conboy, M.J.3    Shen, J.4    Rando, T.A.5
  • 7
    • 36248952802 scopus 로고    scopus 로고
    • The role of Pax genes in the development of tissues and organs: Pax3 and Pax7 regulate muscle progenitor cell functions
    • M. Buckingham, and F. Relaix The role of Pax genes in the development of tissues and organs: Pax3 and Pax7 regulate muscle progenitor cell functions Annu Rev Cell Dev Biol 23 2007 645 673
    • (2007) Annu Rev Cell Dev Biol , vol.23 , pp. 645-673
    • Buckingham, M.1    Relaix, F.2
  • 8
    • 0030860934 scopus 로고    scopus 로고
    • Fusion genes resulting from alternative chromosomal translocations are overexpressed by gene-specific mechanisms in alveolar rhabdomyosarcoma
    • DOI 10.1073/pnas.94.15.8047
    • R.J. Davis, and F.G. Barr Fusion genes resulting from alternative chromosomal translocations are overexpressed by gene-specific mechanisms in alveolar rhabdomyosarcoma Proc Natl Acad Sci U S A 94 1997 8047 8051 (Pubitemid 27343774)
    • (1997) Proceedings of the National Academy of Sciences of the United States of America , vol.94 , Issue.15 , pp. 8047-8051
    • Davis, R.J.1    Barr, F.G.2
  • 9
    • 71549143788 scopus 로고    scopus 로고
    • Phosphorylation of serine 205 by the protein kinase CK2 persists on Pax3-FOXO1, but not Pax3, throughout early myogenic differentiation
    • K.N. Dietz, P.J. Miller, and A.D. Hollenbach Phosphorylation of serine 205 by the protein kinase CK2 persists on Pax3-FOXO1, but not Pax3, throughout early myogenic differentiation Biochemistry 48 2009 11786 11795
    • (2009) Biochemistry , vol.48 , pp. 11786-11795
    • Dietz, K.N.1    Miller, P.J.2    Hollenbach, A.D.3
  • 10
    • 0037383322 scopus 로고    scopus 로고
    • GSK-3: Tricks of the trade for a multi-tasking kinase
    • DOI 10.1242/jcs.00384
    • B.W. Doble, and J.R. Woodgett GSK-3: tricks of the trade for a multi-tasking kinase J Cell Sci 116 2003 1175 1186 (Pubitemid 36410657)
    • (2003) Journal of Cell Science , vol.116 , Issue.7 , pp. 1175-1186
    • Doble, B.W.1    Woodgett, J.R.2
  • 11
    • 0029074993 scopus 로고
    • Pax3 inhibits myogenic differentiation of cultured myoblast cells
    • J.A. Epstein, P. Lam, L. Jepeal, R.L. Maas, and D.N. Shapiro Pax3 inhibits myogenic differentiation of cultured myoblast cells J Biol Chem 270 1995 11719 11722
    • (1995) J Biol Chem , vol.270 , pp. 11719-11722
    • Epstein, J.A.1    Lam, P.2    Jepeal, L.3    Maas, R.L.4    Shapiro, D.N.5
  • 12
    • 0031861728 scopus 로고    scopus 로고
    • Tumor-specific PAX3-FKHR transcription factor, but not PAX3, activates the platelet-derived growth factor alpha receptor
    • J.A. Epstein, B. Song, M. Lakkis, and C. Wang Tumor-specific PAX3-FKHR transcription factor, but not PAX3, activates the platelet-derived growth factor alpha receptor Mol Cell Biol 18 1998 4118 4130 (Pubitemid 28287935)
    • (1998) Molecular and Cellular Biology , vol.18 , Issue.7 , pp. 4118-4130
    • Epstein, J.A.1    Song, B.2    Lakkis, M.3    Wang, C.4
  • 13
    • 0035477020 scopus 로고    scopus 로고
    • GSK3 takes centre stage more than 20 years after its discovery
    • DOI 10.1042/0264-6021:3590001
    • S. Frame, and P. Cohen GSK3 takes centre stage more than 20 years after its discovery Biochem J 359 2001 1 16 (Pubitemid 32939202)
    • (2001) Biochemical Journal , vol.359 , Issue.1 , pp. 1-16
    • Frame, S.1    Cohen, P.2
  • 14
    • 0028881603 scopus 로고
    • The PAX3-FKHR fusion protein created by the t(2;13) translocation in alveolar rhabdomyosarcomas is a more potent transcriptional activator than PAX3
    • W.J. Fredericks, N. Galili, S. Mukhopadhyay, G. Rovera, J. Bennicelli, and F.G. Barr The PAX3-FKHR fusion protein created by the t(2;13) translocation in alveolar rhabdomyosarcomas is a more potent transcriptional activator than PAX3 Mol Cell Biol 15 1995 1522 1535
    • (1995) Mol Cell Biol , vol.15 , pp. 1522-1535
    • Fredericks, W.J.1    Galili, N.2    Mukhopadhyay, S.3    Rovera, G.4    Bennicelli, J.5    Barr, F.G.6
  • 16
    • 0023257034 scopus 로고
    • Characterization of cell lines derived from xenografts of childhood rhabdomyosarcoma
    • B.J. Hazelton, J.A. Houghton, D.M. Parham, E.C. Douglass, P.M. Torrance, and H. Holt Characterization of cell lines derived from xenografts of childhood rhabdomyosarcoma Cancer Res 47 1987 4501 4507 (Pubitemid 17128155)
    • (1987) Cancer Research , vol.47 , Issue.16 , pp. 4501-4507
    • Hazelton, B.J.1    Houghton, J.A.2    Parham, D.M.3
  • 17
    • 0033168203 scopus 로고    scopus 로고
    • The Pax3-FKHR oncoprotein is unresponsive to the Pax3-associated repressor hDaxx
    • DOI 10.1093/emboj/18.13.3702
    • A.D. Hollenbach, J.E. Sublett, C.J. McPherson, and G. Grosveld The Pax3-FKHR oncoprotein is unresponsive to the Pax3-associated repressor hDaxx EMBO J 18 1999 3702 3711 (Pubitemid 29308849)
    • (1999) EMBO Journal , vol.18 , Issue.13 , pp. 3702-3711
    • Hollenbach, A.D.1    Sublett, J.E.2    McPherson, C.J.3    Grosveld, G.4
  • 18
    • 0026636883 scopus 로고
    • The regulation of transcription by phosphorylation
    • T. Hunter, and M. Karin The regulation of transcription by phosphorylation Cell 70 1992 375 387
    • (1992) Cell , vol.70 , pp. 375-387
    • Hunter, T.1    Karin, M.2
  • 20
    • 0032906216 scopus 로고    scopus 로고
    • The oncogenic potential of the Pax3-FKHR fusion protein requires the Pax3 homeodomain recognition helix but not the Pax3 paired-box DNA binding domain
    • P.Y. Lam, J.E. Sublett, A.D. Hollenbach, and M.F. Roussel The oncogenic potential of the Pax3-FKHR fusion protein requires the Pax3 homeodomain recognition helix but not the Pax3 paired-box DNA binding domain Mol Cell Biol 19 1999 594 601 (Pubitemid 29018461)
    • (1999) Molecular and Cellular Biology , vol.19 , Issue.1 , pp. 594-601
    • Lam, P.Y.P.1    Sublett, J.E.2    Hollenbach, A.D.3    Roussel, M.F.4
  • 21
    • 55549094839 scopus 로고    scopus 로고
    • Identification of serine 205 as a site of phosphorylation on Pax3 in proliferating but not differentiating primary myoblasts
    • P.J. Miller, K.N. Dietz, and A.D. Hollenbach Identification of serine 205 as a site of phosphorylation on Pax3 in proliferating but not differentiating primary myoblasts Protein Sci 17 2008 1979 1986
    • (2008) Protein Sci , vol.17 , pp. 1979-1986
    • Miller, P.J.1    Dietz, K.N.2    Hollenbach, A.D.3
  • 22
    • 34548525530 scopus 로고    scopus 로고
    • The oncogenic fusion protein Pax3-FKHR has a greater post-translational stability relative to Pax3 during early myogenesis
    • DOI 10.1016/j.bbagen.2007.06.016, PII S030441650700150X
    • P.J. Miller, and A.D. Hollenbach The oncogenic fusion protein Pax3-FKHR has a greater post-translational stability relative to Pax3 during early myogenesis Biochim Biophys Acta 1770 2007 1450 1458 (Pubitemid 47384992)
    • (2007) Biochimica et Biophysica Acta - General Subjects , vol.1770 , Issue.10 , pp. 1450-1458
    • Miller, P.J.1    Hollenbach, A.D.2
  • 23
    • 0033760404 scopus 로고    scopus 로고
    • Pediatric rhabdomyosarcoma cell lines are resistant to Fas-induced apoptosis and highly sensitive to TRAIL-induced apoptosis
    • I. Petak, L. Douglas, D.M. Tillman, R. Vernes, and J.A. Houghton Pediatric rhabdomyosarcoma cell lines are resistant to Fas-induced apoptosis and highly sensitive to TRAIL-induced apoptosis Clin Cancer Res 6 2000 4119 4127
    • (2000) Clin Cancer Res , vol.6 , pp. 4119-4127
    • Petak, I.1    Douglas, L.2    Tillman, D.M.3    Vernes, R.4    Houghton, J.A.5
  • 24
    • 0030635069 scopus 로고    scopus 로고
    • Methods for myoblast transplantation
    • T.A. Rando, and H.M. Blau Methods for myoblast transplantation Methods Cell Biol 52 1997 261 272 (Pubitemid 128787397)
    • (1997) Methods in Cell Biology , Issue.52 , pp. 261-272
    • Rando, T.A.1    Blau, H.M.2
  • 25
    • 0027366917 scopus 로고
    • Fusion of PAX3 to a member of the forkhead family of transcription factors in human alveolar rhabdomyosarcoma
    • D.N. Shapiro, J.E. Sublett, B. Li, J.R. Downing, and C.W. Naeve Fusion of PAX3 to a member of the forkhead family of transcription factors in human alveolar rhabdomyosarcoma Cancer Res 53 1993 5108 5112 (Pubitemid 23333374)
    • (1993) Cancer Research , vol.53 , Issue.21 , pp. 5108-5112
    • Shapiro, D.N.1    Sublett, J.E.2    Li, B.3    Downing, J.R.4    Naeve, C.W.5
  • 26
    • 38049134604 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3 suppresses myogenic differentiation through negative regulation of NFATc3
    • J.L. van der Velden, A.M. Schols, J. Willems, M.C. Kelders, and R.C. Langen Glycogen synthase kinase 3 suppresses myogenic differentiation through negative regulation of NFATc3 J Biol Chem 283 2008 358 366
    • (2008) J Biol Chem , vol.283 , pp. 358-366
    • Van Der Velden, J.L.1    Schols, A.M.2    Willems, J.3    Kelders, M.C.4    Langen, R.C.5
  • 27
    • 0028345647 scopus 로고
    • Pax-3 expression in segmental mesoderm marks early stages in myogenic cell specification
    • B.A. Williams, and C.P. Ordahl Pax-3 expression in segmental mesoderm marks early stages in myogenic cell specification Development 120 1994 785 796 (Pubitemid 24111544)
    • (1994) Development , vol.120 , Issue.4 , pp. 785-796
    • Williams, B.A.1    Ordahl, C.P.2
  • 28
    • 72949120805 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3 regulates PAX3-FKHR-mediated cell proliferation in human alveolar rhabdomyosarcoma cells
    • F.Y. Zeng, H. Dong, J. Cui, L. Liu, and T. Chen Glycogen synthase kinase 3 regulates PAX3-FKHR-mediated cell proliferation in human alveolar rhabdomyosarcoma cells Biochem Biophys Res Commun 391 2010 1049 1055
    • (2010) Biochem Biophys Res Commun , vol.391 , pp. 1049-1055
    • Zeng, F.Y.1    Dong, H.2    Cui, J.3    Liu, L.4    Chen, T.5


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