Mono- and dinuclear (η6-arene) ruthenium(II) benzaldehyde thiosemicarbazone complexes: Synthesis, characterization and cytotoxicity

Inorganic Chemistry Communications

Volumn 14, Issue 6, 2011, Pages 956-960

  Stringer, Tameryn ^a   Therrien, Bruno ^b   Hendricks, Denver T ^a   Guzgay, Hajira ^a   Smith, Gregory S ^a  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

^b UNIVERSITY OF NEUCHÂTEL   (Switzerland)

Author keywords

Anticancer drugs; Arene ruthenium(II); Bioorganometallic chemistry; Thiosemicarbazones

Indexed keywords

EID: 79955883452     PISSN: 13877003     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.inoche.2011.03.041     Document Type: Article

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52. 2 (24 hours), after which aqueous DMSO solutions of each compound (10 μl, with a constant final DMSO concentration of 0.2%) were plated at various concentrations. After a 48 hour incubation period, MTT (10 μl) solution was added to each well. After further 4 hour incubation, solubilisation solution (100 μl) was added to each well, and plates were incubated overnight. Plates were read at 595 nm using a BioTek microplate reader.