Lentivirus mediated IL-17R blockade improves diastolic cardiac function in spontaneously hypertensive rats

Experimental and Molecular Pathology

Volumn 91, Issue 1, 2011, Pages 362-367

  Liu, Wei ^a   Wang, Xueting ^a   Feng, Weiwei ^a   Li, Shuqing ^a   Tian, Wendan ^a   Xu, Tengfei ^a   Song, Yunyan ^b   Zhang, Zhiyi ^a  

^a THE FIRST AFFILIATED HOSPITAL OF HARBIN MEDICAL UNIVERSITY   (China)

^b Harbin Children's Hospital 150020   (China)

Author keywords

Cardiac fibrosis; Diastolic function; IL 17RA; SHR

Indexed keywords

COLLAGEN TYPE 1; COLLAGEN TYPE 3; GELATINASE A; GELATINASE B; GREEN FLUORESCENT PROTEIN; INTERLEUKIN 17; INTERLEUKIN 17 RECEPTOR; INTERLEUKIN 17 RECEPTOR A; LENTIVIRUS VECTOR; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLLAGEN METABOLISM; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; ECHOCARDIOGRAPHY; HEART FUNCTION; HEART MUSCLE FIBROSIS; HEART VENTRICLE HYPERTROPHY; HISTOPATHOLOGY; HUMAN; IMMUNOBLOTTING; MALE; NONHUMAN; PROTEIN CROSS LINKING; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; SPONTANEOUSLY HYPERTENSIVE RAT; SYSTOLIC BLOOD PRESSURE; VIRAL GENE DELIVERY SYSTEM; WISTAR KYOTO RAT;

ANIMALS; COLLAGEN TYPE III; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; ELECTROCARDIOGRAPHY; FIBROSIS; HEART; HEART FAILURE; HEART VENTRICLES; HEMODYNAMICS; HUMANS; HYPERTENSION; INTERLEUKIN-17; LENTIVIRUS; MALE; MATRIX METALLOPROTEINASES; MYOCARDIUM; RATS; RATS, INBRED SHR; RATS, INBRED WKY; RECEPTORS, INTERLEUKIN-17; TISSUE INHIBITOR OF METALLOPROTEINASES; TRANSFECTION;

LENTIVIRUS; RATTUS;

EID: 79955870570     PISSN: 00144800     EISSN: 10960945     Source Type: Journal    
DOI: 10.1016/j.yexmp.2011.04.003     Document Type: Article

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