-
1
-
-
77649126524
-
Heart disease and stroke statistics - 2010 Update: A report from the American Heart Association
-
Lloyd-Jones D, Adams RJ, Brown TM, et al.: Heart disease and stroke statistics - 2010 update: A report from the American Heart Association. Circulation 2010, 121:e46-e215.
-
(2010)
Circulation
, vol.121
-
-
Lloyd-Jones, D.1
Adams, R.J.2
Brown, T.M.3
-
2
-
-
39549119320
-
Evolving concepts and technologies in mitral valve repair
-
DOI 10.1161/CIRCULATIONAHA.107.702035, PII 0000301720080219000015
-
Fedak PW, McCarthy PM, Bonow RO: Evolving concepts and technologies in mitral valve repair. Circulation 2008, 117:963-974. (Pubitemid 351278391)
-
(2008)
Circulation
, vol.117
, Issue.7
, pp. 963-974
-
-
Fedak, P.W.M.1
McCarthy, P.M.2
Bonow, R.O.3
-
3
-
-
0027552609
-
Differential collagen distribution in the mitral valve and its influence on biomechanical behaviour
-
Kunzelman KS, Cochran RP, Murphree SS, et al.: Differential collagen distribution in the mitral valve and its influence on biomechanical behaviour. J Heart Valve Dis 1993, 2:236-244.
-
(1993)
J Heart Valve Dis
, vol.2
, pp. 236-244
-
-
Kunzelman, K.S.1
Cochran, R.P.2
Murphree, S.S.3
-
4
-
-
48449100805
-
Valve proteoglycan content and glycosaminoglycan fine structure are unique to microstructure, mechanical load and age: Relevance to an age-specific tissue-engineered heart valve
-
Stephens EH, Chu CK, Grande-Allen KJ: Valve proteoglycan content and glycosaminoglycan fine structure are unique to microstructure, mechanical load and age: Relevance to an age-specific tissue-engineered heart valve. Acta Biomater 2008, 4:1148-1160.
-
(2008)
Acta Biomater
, vol.4
, pp. 1148-1160
-
-
Stephens, E.H.1
Chu, C.K.2
Grande-Allen, K.J.3
-
5
-
-
33645498146
-
Biaixal stress-stretch behavior of the mitral valve anterior leaflet at physiologic strain rates
-
Grashow JS, Yoganathan AP, Sacks MS: Biaixal stress-stretch behavior of the mitral valve anterior leaflet at physiologic strain rates. Ann Biomed Eng 2006, 34:315-325.
-
(2006)
Ann Biomed Eng
, vol.34
, pp. 315-325
-
-
Grashow, J.S.1
Yoganathan, A.P.2
Sacks, M.S.3
-
6
-
-
0028820708
-
Biaxial mechanical behavior of excised porcine mitral valve leaflets
-
May-Newman K, Yin FC: Biaxial mechanical behavior of excised porcine mitral valve leaflets. Am J Physiol 1995, 269:H1319-1327.
-
(1995)
Am J Physiol
, vol.269
-
-
May-Newman, K.1
Yin, F.C.2
-
7
-
-
66949144033
-
Differences in collagen cross-linking between the four valves of the bovine heart: A possible role in adaptation to mechanical fatigue
-
This work finds considerable differences in collagen cross-linking between the semilunar and atrioventricular valves, which may have implications for the fundamental distinctions between aortic valve disease (calcific) and MV disease (myxomatous)
-
Aldous IG, Veres SP, Jahangir A, Lee JM: Differences in collagen cross-linking between the four valves of the bovine heart: A possible role in adaptation to mechanical fatigue. Am J Physiol Heart Circ Physiol 2009, 296:H1898-1906. This work finds considerable differences in collagen cross-linking between the semilunar and atrioventricular valves, which may have implications for the fundamental distinctions between aortic valve disease (calcific) and MV disease (myxomatous).
-
(2009)
Am J Physiol Heart Circ Physiol
, vol.296
-
-
Aldous, I.G.1
Veres, S.P.2
Jahangir, A.3
Lee, J.M.4
-
8
-
-
0038724493
-
A structural basis for the size-related mechanical properties of mitral valve chordae tendineae
-
DOI 10.1016/S0021-9290(03)00109-X
-
Liao J, Vesely I: A structural basis for the size-related mechanical properties of mitral valve chordae tendineae. J Biomech 2003, 36:1125-1133. (Pubitemid 36794109)
-
(2003)
Journal of Biomechanics
, vol.36
, Issue.8
, pp. 1125-1133
-
-
Liao, J.1
Vesely, I.2
-
9
-
-
68949176943
-
Ultrastructure of porcine mitral valve chordae tendineae
-
Liao J, Priddy LB, Wang B, et al.: Ultrastructure of porcine mitral valve chordae tendineae. J Heart Valve Dis 2009, 18:292-299.
-
(2009)
J Heart Valve Dis
, vol.18
, pp. 292-299
-
-
Liao, J.1
Priddy, L.B.2
Wang, B.3
-
10
-
-
77449153840
-
Characterization of mitral valve anterior leaflet perfusion patterns
-
This study is the first in vivo demonstration of perfusion of the blood vessels within the MV leaflets and chordae
-
Swanson JC, Davis LR, Arata K, et al.: Characterization of mitral valve anterior leaflet perfusion patterns. J Heart Valve Dis 2009, 18:488-495. This study is the first in vivo demonstration of perfusion of the blood vessels within the MV leaflets and chordae.
-
(2009)
J Heart Valve Dis
, vol.18
, pp. 488-495
-
-
Swanson, J.C.1
Davis, L.R.2
Arata, K.3
-
11
-
-
20544450624
-
Structural characterization of the chordae tendineae in native porcine mitral valves
-
DOI 10.1016/j.athoracsur.2005.02.011, PII S000349750500189X
-
Ritchie J, Warnock JN, Yoganathan AP: Structural characterization of the chordae tendineae in native porcine mitral valves. Ann Thorac Surg 2005, 80:189-197. (Pubitemid 40840207)
-
(2005)
Annals of Thoracic Surgery
, vol.80
, Issue.1
, pp. 189-197
-
-
Ritchie, J.1
Warnock, J.N.2
Yoganathan, A.P.3
-
12
-
-
85047677733
-
The vascularization of the heart valves: A comparative study
-
Duran CM, Gunning AJ: The vascularization of the heart valves: A comparative study. Cardiovasc Res 1968, 2:290-296.
-
(1968)
Cardiovasc Res
, vol.2
, pp. 290-296
-
-
Duran, C.M.1
Gunning, A.J.2
-
13
-
-
33748474245
-
Innervation of the atrioventricular and semi-lunar heart valves: A review
-
DOI 10.2143/AC.61.4.2017309
-
Borin C, Vanhercke D, Weyns A: Innervation of the atrioventricular and semi-lunar heart valves: A review. Acta Cardiol 2006, 61:463-469. (Pubitemid 44348623)
-
(2006)
Acta Cardiologica
, vol.61
, Issue.4
, pp. 463-469
-
-
Borin, C.1
Vanhercke, D.2
Weyns, A.3
-
14
-
-
0026573843
-
Stress/strain characteristics of porcine mitral valve tissue: Parallel versus perpendicular collagen orientation
-
Kunzelman KS, Cochran RP: Stress/strain characteristics of porcine mitral valve tissue: Parallel versus perpendicular collagen orientation. J Card Surg 1992, 7:71-78.
-
(1992)
J Card Surg
, vol.7
, pp. 71-78
-
-
Kunzelman, K.S.1
Cochran, R.P.2
-
15
-
-
34248172837
-
The relation between collagen fibril kinematics and mechanical properties in the mitral valve anterior leaflet
-
DOI 10.1115/1.2401186
-
Liao J, Yang L, Grashow J, Sacks MS: The relation between collagen fibril kinematics and mechanical properties in the mitral valve anterior leaflet. J Biomech Eng 2007, 129:78-87. (Pubitemid 46722311)
-
(2007)
Journal of Biomechanical Engineering
, vol.129
, Issue.1
, pp. 78-87
-
-
Liao, J.1
Yang, L.2
Grashow, J.3
Sacks, M.S.4
-
16
-
-
77649260964
-
Age-related changes in material behavior of porcine mitral and aortic valves and correlation to matrix composition
-
Stephens EH, de Jonge N, McNeillMP, et al.: Age-related changes in material behavior of porcine mitral and aortic valves and correlation to matrix composition. Tissue Eng Part A 2010, 16:867-878.
-
(2010)
Tissue Eng Part A
, vol.16
, pp. 867-878
-
-
Stephens, E.H.1
De McNeillmp, J.N.2
-
17
-
-
12344329453
-
Nonhomogeneous deformation in the anterior leaflet of the mitral valve
-
Chen L, McCulloch AD, May-Newman K: Nonhomogeneous deformation in the anterior leaflet of the mitral valve. Ann Biomed Eng 2004, 32:1599-1606. (Pubitemid 40121293)
-
(2004)
Annals of Biomedical Engineering
, vol.32
, Issue.12
, pp. 1599-1606
-
-
Chen, L.1
McCulloch, A.D.2
May-Newman, K.3
-
18
-
-
33748757430
-
In-Vivo Dynamic Deformation of the Mitral Valve Anterior Leaflet
-
DOI 10.1016/j.athoracsur.2006.03.117, PII S0003497506007247
-
Sacks MS, Enomoto Y, Graybill JR, et al.: In-vivo dynamic deformation of the mitral valve anterior leaflet. Ann Thorac Surg 2006, 82:1369-1377. (Pubitemid 44402317)
-
(2006)
Annals of Thoracic Surgery
, vol.82
, Issue.4
, pp. 1369-1377
-
-
Sacks, M.S.1
Enomoto, Y.2
Graybill, J.R.3
Merryman, W.D.4
Zeeshan, A.5
Yoganathan, A.P.6
Levy, R.J.7
Gorman, R.C.8
Gorman III, J.H.9
-
19
-
-
33845331713
-
Distribution of the microelastic properties within the human anterior mitral leaflet
-
DOI 10.1016/j.ultrasmedbio.2006.06.011, PII S0301562906016851
-
Jensen AS, Baandrup U, Hasenkam JM, et al.: Distribution of the microelastic properties within the human anterior mitral leaflet. Ultrasound Med Biol 2006, 32:1943-1948. (Pubitemid 44880536)
-
(2006)
Ultrasound in Medicine and Biology
, vol.32
, Issue.12
, pp. 1943-1948
-
-
Jensen, A.S.1
Baandrup, U.2
Hasenkam, J.M.3
Kundu, T.4
Jorgensen, C.S.5
-
20
-
-
34248161234
-
Planar biaxial creep and stress relaxation of the mitral valve anterior leaflet
-
Grashow JS, Sacks MS, Liao J, Yoganathan AP: Planar biaxial creep and stress relaxation of the mitral valve anterior leaflet. Ann Biomed Eng 2006, 34:1509-1518.
-
(2006)
Ann Biomed Eng
, vol.34
, pp. 1509-1518
-
-
Grashow, J.S.1
Sacks, M.S.2
Liao, J.3
Yoganathan, A.P.4
-
21
-
-
0030685087
-
Mitral subvalvular apparatus: Different functions of primary and secondary chordae
-
Obadia JF, Casali C, Chassignolle JF, Janier M: Mitral subvalvular apparatus: Different functions of primary and secondary chordae. Circulation 1997, 96:3124-3128. (Pubitemid 27500117)
-
(1997)
Circulation
, vol.96
, Issue.9
, pp. 3124-3128
-
-
Obadia, J.F.1
Casali, C.2
Chassignolle, J.F.3
Janier, M.4
-
22
-
-
0035991248
-
Differential tension between secondary and primary mitral chordae in an acute in-vivo porcine model
-
Lomholt M, Nielsen SL, Hansen SB, et al.: Differential tension between secondary and primary mitral chordae in an acute in-vivo porcine model. J Heart Valve Dis 2002, 11:337-345. (Pubitemid 34578449)
-
(2002)
Journal of Heart Valve Disease
, vol.11
, Issue.3
, pp. 337-345
-
-
Lomholt, M.1
Nielsen, S.L.2
Hansen, S.B.3
Andersen, N.T.4
Hasenkam, J.M.5
-
23
-
-
0017180684
-
Morphology and relationship to extensibility curves of human mitral valve chordae tendineae
-
Lim KO, Boughner DR: Morphology and relationship to extensibility curves of human mitral valve chordae tendineae. Circ Res 1976, 39:580-585.
-
(1976)
Circ Res
, vol.39
, pp. 580-585
-
-
Lim, K.O.1
Boughner, D.R.2
-
24
-
-
33845671383
-
Skewness angle of interfibrillar proteoglycans increases with applied load on mitral valve chordae tendineae
-
DOI 10.1016/j.jbiomech.2005.12.011, PII S0021929005005531
-
Liao J, Vesely I: Skewness angle of interfibrillar proteoglycans increases with applied load on mitral valve chordae tendineae. J Biomech 2007, 40:390-398. (Pubitemid 44958569)
-
(2007)
Journal of Biomechanics
, vol.40
, Issue.2
, pp. 390-398
-
-
Liao, J.1
Vesely, I.2
-
25
-
-
77955346225
-
Mechanics of the mitral valve strut chordae insertion region
-
Padala M, Sacks MS, Liou SW, et al.: Mechanics of the mitral valve strut chordae insertion region. J Biomech Eng 2010, 132:081004.
-
(2010)
J Biomech Eng
, vol.132
, pp. 081004
-
-
Padala, M.1
Sacks, M.S.2
Liou, S.W.3
-
26
-
-
36348976915
-
The emerging role of valve interstitial cell phenotypes in regulating heart valve pathobiology
-
DOI 10.2353/ajpath.2007.070251
-
Liu AC, Joag VR, Gotlieb AI: The emerging role of valve interstitial cell phenotypes in regulating heart valve pathobiology. Am J Pathol. 2007, 171:1407-1418. (Pubitemid 350158303)
-
(2007)
American Journal of Pathology
, vol.171
, Issue.5
, pp. 1407-1418
-
-
Liu, A.C.1
Joag, V.R.2
Gotlieb, A.I.3
-
27
-
-
36949032340
-
Age-related changes in collagen synthesis and turnover in porcine heart valves
-
Stephens EH, Grande-Allen KJ: Age-related changes in collagen synthesis and turnover in porcine heart valves. J Heart Valve Dis 2007, 16:672-682. (Pubitemid 350238225)
-
(2007)
Journal of Heart Valve Disease
, vol.16
, Issue.6
, pp. 672-682
-
-
Stephens, E.H.1
Grande-Allen, K.J.2
-
28
-
-
78651393399
-
Functional coupling of valvular interstitial cells and collagen in the mitral leaflet
-
Stephens EH, Durst CA, Swanson JC, et al.: Functional coupling of valvular interstitial cells and collagen in the mitral leaflet. Cell Mol Bioeng 2010, 3:428-437.
-
(2010)
Cell Mol Bioeng
, vol.3
, pp. 428-437
-
-
Stephens, E.H.1
Durst, C.A.2
Swanson, J.C.3
-
29
-
-
33644805453
-
Correlation between heart valve interstitial cell stiffness and transvalvular pressure: Implications for collagen biosynthesis
-
Merryman WD, Youn I, Lukoff HD, et al.: Correlation between heart valve interstitial cell stiffness and transvalvular pressure: Implications for collagen biosynthesis. Am J Physiol Heart Circ Physiol 2006, 290:H224-231.
-
(2006)
Am J Physiol Heart Circ Physiol
, vol.290
-
-
Merryman, W.D.1
Youn, I.2
Lukoff, H.D.3
-
30
-
-
0035923477
-
Activated interstitial myofibroblasts express catabolic enzymes and mediate matrix remodeling in myxomatous heart valves
-
Rabkin E, Aikawa M, Stone JR, et al.: Activated interstitial myofibroblasts express catabolic enzymes and mediate matrix remodeling in myxomatous heart valves. Circulation 2001, 104:2525-2532. (Pubitemid 33104788)
-
(2001)
Circulation
, vol.104
, Issue.21
, pp. 2525-2532
-
-
Rabkin, E.1
Aikawa, M.2
Stone, J.R.3
Fukumoto, Y.4
Libby, P.5
Schoen, F.J.6
-
31
-
-
0037290726
-
The cardiac valve interstitial cell
-
DOI 10.1016/S1357-2725(02)00100-0, PII S1357272502001000
-
Taylor PM, Batten P, Brand NJ, et al.: The cardiac valve interstitial cell. Int J Biochem Cell Biol 2003, 35:113-118. (Pubitemid 35441268)
-
(2003)
International Journal of Biochemistry and Cell Biology
, vol.35
, Issue.2
, pp. 113-118
-
-
Taylor, P.M.1
Batten, P.2
Brand, N.J.3
Thomas, P.S.4
Yacoub, M.H.5
-
32
-
-
39149087647
-
Mitral valvular interstitial cells demonstrate regional, adhesional, and synthetic heterogeneity
-
DOI 10.1159/000108582
-
Blevins TL, Peterson SB, Lee EL, et al.: Mitral valvular interstitial cells demonstrate regional, adhesional, and synthetic heterogeneity. Cells Tissues Organs 2008, 187:113-122. (Pubitemid 351252946)
-
(2008)
Cells Tissues Organs
, vol.187
, Issue.2
, pp. 113-122
-
-
Blevins, T.L.1
Peterson, S.B.2
Lee, E.L.3
Bailey, A.M.4
Frederick, J.D.5
Huynh, T.N.6
Gupta, V.7
Grande-Allen, K.J.8
-
33
-
-
4043127381
-
Valvular myofibroblast activation by transforming growth factor-beta: Implications for pathological extracellular matrix remodeling in heart valve disease
-
DOI 10.1161/01.RES.0000136520.07995.aa
-
Walker GA, Masters KS, Shah DN, et al.: Valvular myofibroblast activation by transforming growth factor-beta: Implications for pathological extracellular matrix remodeling in heart valve disease. Circ Res 2004, 95:253-260. (Pubitemid 39056285)
-
(2004)
Circulation Research
, vol.95
, Issue.3
, pp. 253-260
-
-
Walker, G.A.1
Masters, K.S.2
Shah, D.N.3
Anseth, K.S.4
Leinwand, L.A.5
-
34
-
-
55349103073
-
Transforming growth factor-beta regulates in vitro heart valve repair by activated valve interstitial cells
-
Liu AC, Gotlieb AI: Transforming growth factor-beta regulates in vitro heart valve repair by activated valve interstitial cells. Am J Pathol 2008, 173:1275-1285.
-
(2008)
Am J Pathol
, vol.173
, pp. 1275-1285
-
-
Liu, A.C.1
Gotlieb, A.I.2
-
35
-
-
0036737923
-
Fibroblast growth factor 2 regulation of mitral valve interstitial cell repair in vitro
-
Gotlieb AI, Rosenthal A, Kazemian P: Fibroblast growth factor 2 regulation of mitral valve interstitial cell repair in vitro. J Thorac Cardiovasc Surg 2002, 124:591-597.
-
(2002)
J Thorac Cardiovasc Surg
, vol.124
, pp. 591-597
-
-
Gotlieb, A.I.1
Rosenthal, A.2
Kazemian, P.3
-
36
-
-
44949107350
-
Fibroblast growth factor represses Smad-mediated myofibroblast activation in aortic valvular interstitial cells
-
DOI 10.1096/fj.07-087627
-
Cushing MC, Mariner PD, Liao JT, et al.: Fibroblast growth factor represses smad-mediated myofibroblast activation in aortic valvular interstitial cells. Faseb J 2008, 22:1769-1777. (Pubitemid 351811454)
-
(2008)
FASEB Journal
, vol.22
, Issue.6
, pp. 1769-1777
-
-
Cushing, M.C.1
Mariner, P.D.2
Liao, J.-T.3
Sims, E.A.4
Anseth, K.S.5
-
37
-
-
70349785588
-
Significant changes in mitral valve leaflet matrix composition and turnover with tachycardia-induced cardiomyopathy
-
Stephens EH, Timek TA, Daughters GT, et al.: Significant changes in mitral valve leaflet matrix composition and turnover with tachycardia-induced cardiomyopathy. Circulation 2009, 120: S112-119.
-
(2009)
Circulation
, vol.120
-
-
Stephens, E.H.1
Timek, T.A.2
Daughters, G.T.3
-
38
-
-
57849140532
-
Effect of cyclic mechanical strain on glycosaminoglycan and proteoglycan synthesis by heart valve cells
-
Gupta V, Tseng H, Lawrence BD, Grande-Allen KJ: Effect of cyclic mechanical strain on glycosaminoglycan and proteoglycan synthesis by heart valve cells. Acta Biomater 2009, 5:531-540.
-
(2009)
Acta Biomater
, vol.5
, pp. 531-540
-
-
Gupta, V.1
Tseng, H.2
Lawrence, B.D.3
Grande-Allen, K.J.4
-
39
-
-
33846647470
-
Synthesis of glycosaminoglycans in differently loaded regions of collagen gels seeded with valvular interstitial cells
-
DOI 10.1089/ten.2006.0091
-
Gupta V, Werdenberg JA, Blevins TL, Grande-Allen KJ: Synthesis of glycosaminoglycans in differently loaded regions of collagen gels seeded with valvular interstitial cells. Tissue Eng 2007, 13:41-49. (Pubitemid 46178380)
-
(2007)
Tissue Engineering
, vol.13
, Issue.1
, pp. 41-49
-
-
Gupta, V.1
Werdenberg, J.A.2
Blevins, T.L.3
Grande-Allen, K.J.4
-
40
-
-
44649176440
-
Reversible secretion of glycosaminoglycans and proteoglycans by cyclically stretched valvular cells in 3d culture
-
Gupta V, Werdenberg JA, Lawrence BD, et al.: Reversible secretion of glycosaminoglycans and proteoglycans by cyclically stretched valvular cells in 3d culture. Ann Biomed Eng 2008, 36:1092-1103.
-
(2008)
Ann Biomed Eng
, vol.36
, pp. 1092-1103
-
-
Gupta, V.1
Werdenberg, J.A.2
Lawrence, B.D.3
-
41
-
-
68249138605
-
Active adaptation of the tethered mitral valve: Insights into a compensatory mechanism for functional mitral regurgitation
-
This investigation builds on previous studies of MV remodeling in functional mitral regurgitation by demonstrating that the valvular cells undergo a reactivation of embryonic remodeling pathways
-
Dal-Bianco JP, Aikawa E, Bischoff J, et al.: Active adaptation of the tethered mitral valve: insights into a compensatory mechanism for functional mitral regurgitation. Circulation 2009, 120:334-342. This investigation builds on previous studies of MV remodeling in functional mitral regurgitation by demonstrating that the valvular cells undergo a reactivation of embryonic remodeling pathways.
-
(2009)
Circulation
, vol.120
, pp. 334-342
-
-
Dal-Bianco, J.P.1
Aikawa, E.2
Bischoff, J.3
-
42
-
-
33748754258
-
Reference models for mitral valve tissue engineering based on valve cell phenotype and extracellular matrix analysis
-
DOI 10.1159/000094902
-
Flanagan TC, Black A, O'Brien M, et al.: Reference models for mitral valve tissue engineering based on valve cell phenotype and extracellular matrix analysis. Cells Tissues Organs 2006, 183:12-23. (Pubitemid 44401339)
-
(2006)
Cells Tissues Organs
, vol.183
, Issue.1
, pp. 12-23
-
-
Flanagan, T.C.1
Black, A.2
O'Brien, M.3
Smith, T.J.4
Pandit, A.S.5
-
43
-
-
28844491710
-
A collagen-glycosaminoglycan co-culture model for heart valve tissue engineering applications
-
DOI 10.1016/j.biomaterials.2005.10.031, PII S0142961205010082
-
Flanagan TC, Wilkins B, Black A, et al.: A collagen-glycosaminoglycan co-culture model for heart valve tissue engineering applications. Biomaterials 2006, 27:2233-2246. (Pubitemid 41774535)
-
(2006)
Biomaterials
, vol.27
, Issue.10
, pp. 2233-2246
-
-
Flanagan, T.C.1
Wilkins, B.2
Black, A.3
Jockenhoevel, S.4
Smith, T.J.5
Pandit, A.S.6
-
44
-
-
17644380642
-
Spatial heterogeneity of endothelial phenotypes correlates with side-specific vulnerability to calcification in normal porcine aortic valves
-
DOI 10.1161/01.RES.0000161998.92009.64
-
Simmons CA, Grant GR, Manduchi E, Davies PF: Spatial heterogeneity of endothelial phenotypes correlates with side-specific vulnerability to calcification in normal porcine aortic valves. Circ Res 2005, 96:792-799. (Pubitemid 40559519)
-
(2005)
Circulation Research
, vol.96
, Issue.7
, pp. 792-799
-
-
Simmons, C.A.1
Grant, G.R.2
Manduchi, E.3
Davies, P.F.4
-
45
-
-
1642286936
-
Characterization of statically loaded tissue-engineered mitral valve chordae tendineae
-
Shi Y, Vesely I: Characterization of statically loaded tissue-engineered mitral valve chordae tendineae. J Biomed Mater Res A 2004, 69:26-39. (Pubitemid 38364957)
-
(2004)
Journal of Biomedical Materials Research - Part A
, vol.69
, Issue.1
, pp. 26-39
-
-
Shi, Y.1
Vesely, I.2
-
46
-
-
33846917993
-
Progress in developing a composite tissue-engineered aortic valve
-
1616150, Proceedings of the 2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005
-
Vesely I, Shi Y, Dobkin D, et al.: Progress in developing a composite tissue-engineered aortic valve. Conf Proc IEEE Eng Med Biol Soc 2005, 7:7129-7130. (Pubitemid 46230622)
-
(2005)
Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
, vol.7 VOLS
, pp. 7129-7130
-
-
Vesely, I.1
Shi, Y.2
Dobkin, D.3
Iyer, R.4
Soundararajan, A.5
-
47
-
-
33750620529
-
Novel geometries for tissue-engineered tendonous collagen constructs
-
DOI 10.1089/ten.2006.12.2601
-
Shi Y, Rittman L, Vesely I: Novel geometries for tissue-engineered tendonous collagen constructs. Tissue Eng 2006, 12:2601-2609. (Pubitemid 46141282)
-
(2006)
Tissue Engineering
, vol.12
, Issue.9
, pp. 2601-2609
-
-
Shi, Y.1
Rittman, L.2
Vesely, I.3
-
48
-
-
79953215687
-
Design and mechanical evaluation of a physiological mitral valve organ culture system
-
Gheewala N, Grande-Allen KJ: Design and mechanical evaluation of a physiological mitral valve organ culture system. Cardiovasc Eng Technol 2010, 1:123-131.
-
(2010)
Cardiovasc Eng Technol
, vol.1
, pp. 123-131
-
-
Gheewala, N.1
Grande-Allen, K.J.2
-
49
-
-
77952009418
-
Design of a miniature tissue culture system to culture mouse heart valves
-
This new bioreactor device will allow the in vitro culture of a mouse heart. Using this system, scientists can leverage the enormous range of knockout and transgenic mouse models of cardiovascular and other diseases to understand the impact of these genes on the biology and pathology of heart valves and other cardiac tissues
-
Lieber SC, Kruithof BP, Aubry N, et al.: Design of a miniature tissue culture system to culture mouse heart valves. Ann Biomed Eng 2010, 38:674-682. This new bioreactor device will allow the in vitro culture of a mouse heart. Using this system, scientists can leverage the enormous range of knockout and transgenic mouse models of cardiovascular and other diseases to understand the impact of these genes on the biology and pathology of heart valves and other cardiac tissues.
-
(2010)
Ann Biomed Eng
, vol.38
, pp. 674-682
-
-
Lieber, S.C.1
Kruithof, B.P.2
Aubry, N.3
-
50
-
-
78149234492
-
Transforming growth factor beta, bone morphogenetic protein, and vascular endothelial growth factor mediate phenotype maturation and tissue remodeling by embryonic valve progenitor cells: Relevance for heart valve tissue engineering
-
This work exemplifies the innovative combination of developmental biology and bioengineering strategies to understand the remodeling principles that are desired in the regeneration of replacement tissues. These approaches can also be used to investigate pathologic remodeling of heart valves, because it is believed that some valve disease mechanisms may invoke regression to embryonic phenotypes
-
Chiu YN, Norris RA, Mahler G, et al.: Transforming growth factor beta, bone morphogenetic protein, and vascular endothelial growth factor mediate phenotype maturation and tissue remodeling by embryonic valve progenitor cells: Relevance for heart valve tissue engineering. Tissue Eng Part A 2010, 16:3375-3383. This work exemplifies the innovative combination of developmental biology and bioengineering strategies to understand the remodeling principles that are desired in the regeneration of replacement tissues. These approaches can also be used to investigate pathologic remodeling of heart valves, because it is believed that some valve disease mechanisms may invoke regression to embryonic phenotypes.
-
(2010)
Tissue Eng Part A
, vol.16
, pp. 3375-3383
-
-
Chiu, Y.N.1
Norris, R.A.2
Mahler, G.3
-
51
-
-
78049420977
-
Mitral valvular interstitial cell responses to substrate stiffness depend on age and anatomic region
-
Stephens EH, Durst CA, West JL, Grande-Allen KJ: Mitral valvular interstitial cell responses to substrate stiffness depend on age and anatomic region. Acta Biomater 2011, 7:75-82.
-
(2011)
Acta Biomater
, vol.7
, pp. 75-82
-
-
Stephens, E.H.1
Durst, C.A.2
West, J.L.3
Grande-Allen, K.J.4
|