Regulation of hypoxiainduced mRNA expressions of HIF1α and osteopontin and in vitro radiosensitization by tirapazamine in human nasopharyngeal carcinoma HNE1 and CNE1 cells

Chinese Journal of Cancer

Volumn 29, Issue 2, 2010, Pages 126-130

  Xu, Peng ^a   Huang, Jian Ming ^b   Ren, Yuan ^b   Zha, Xiao ^b   Deng, Bi Fang ^b   Wu, Jun Hui ^b   Lang, Jin Yi ^b  

^a GUANGXI MEDICAL UNIVERSITY   (China)

^b SICHUAN CANCER HOSPITAL   (China)

Author keywords

HIF 1 ; Irradiation; Nasopharyngeal carcinoma; Osteopontin; Tirapazamine

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; MESSENGER RNA; OSTEOPONTIN; OXYGEN; TIRAPAZAMINE; ANTINEOPLASTIC AGENT; COBALT; RADIOSENSITIZING AGENT; SPP1 PROTEIN, HUMAN; TRIAZINE DERIVATIVE;

AEROBIC CAPACITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CELL ASSAY; CELL HYPOXIA; CELL SPECIFICITY; CELL STRAIN CNE 1; CELL STRAIN HNE 1; CELL SURVIVAL; COLONY FORMATION; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION REGULATION; GROWTH INHIBITION; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; NASOPHARYNX CARCINOMA; RADIATION EXPOSURE; RADIOSENSITIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SURVIVAL RATE; DRUG EFFECT; GENETICS; METABOLISM; NASOPHARYNX TUMOR; PATHOLOGY; RADIATION DOSE; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; CELL HYPOXIA; CELL LINE, TUMOR; CELL SURVIVAL; COBALT RADIOISOTOPES; DOWN-REGULATION; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INHIBITORY CONCENTRATION 50; NASOPHARYNGEAL NEOPLASMS; OSTEOPONTIN; RADIATION TOLERANCE; RADIATION-SENSITIZING AGENTS; RNA, MESSENGER; TRIAZINES;

EID: 79955847977     PISSN: 1000467X     EISSN: 1944446X     Source Type: Journal    
DOI: 10.5732/cjc.009.10500     Document Type: Article

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