Associations of endogenous testosterone and lipid profiles in middle-aged to older Taiwanese men

International Journal of Impotence Research

Volumn 23, Issue 2, 2011, Pages 62-69

  Jiann, B P ^a   Hsieh, J T ^b   Liu, S P ^b   Hsu, S H J ^b   Wu, H C ^c  

^a KAOHSIUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^c CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

high density lipoprotein cholesterol; low density lipoprotein cholesterol; postprandial triglycerides; testosterone

Indexed keywords

HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIPID; LOW DENSITY LIPOPROTEIN CHOLESTEROL; SEX HORMONE BINDING GLOBULIN; TESTOSTERONE; TRIACYLGLYCEROL;

ADULT; AGING; ANDROGEN DEFICIENCY; ARTICLE; BODY MASS; CONTROLLED STUDY; DIABETES MELLITUS; DIET RESTRICTION; HUMAN; HYPERTENSION; LIPID ANALYSIS; LIPID BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; TAIWAN; TESTOSTERONE BLOOD LEVEL;

ADULT; AGED; AGED, 80 AND OVER; FASTING; HUMANS; LIPIDS; MIDDLE AGED; SEX HORMONE-BINDING GLOBULIN; TAIWAN; TESTOSTERONE;

EID: 79955841551     PISSN: 09559930     EISSN: 14765489     Source Type: Journal    
DOI: 10.1038/ijir.2011.5     Document Type: Article

References (42)

1. Berenson GS, Srinivasan SR, Cresanta JL, Foster TA, Webber LS. Dynamic changes of serum lipoproteins in children during adolescence and sexual maturation. Am J Epidemiol 1981; 113: 157-170. (Pubitemid 11183757)
2. Kirkland RT, Keenan BS, Probstfield JL, Patsch W, Lin TL, Clayton GWet al. Decrease in plasma high-density lipoprotein cholesterol levels at puberty in boys with delayed adoles¬cence: correlation with plasma testosterone levels. JAMA 1987; 257: 502-507. (Pubitemid 17000704)
3. Wu FC, von Eckardstein A. Androgens and coronary artery disease. Endocr Rev 2003; 24: 183-217. (Pubitemid 36515284)
4. Kaufman JM, Vermeulen A. The decline of androgen levels in elderly men and its clinical and therapeutic implications. Endocr Rev 2005; 26: 833-876. (Pubitemid 41428540)
5. Lloyd-Jones DM, Larson MG, Beiser A, Levy D. Lifetime risk of developing coronary heart disease. Lancet 1999; 353: 89-92. (Pubitemid 29088076)
6. Laughlin GA, Barrett-Connor E, Bergstrom J. Low serum testosterone and mortality in older men. J Clin Endocrinol Metab 2008; 93: 68-75.
7. Khaw KT, Dowsett M, Folkerd E, Bingham S, Wareham N, Luben R et al. Endogenous testosterone and mortality due to all causes, cardiovascular disease, and cancer in men: European prospective investigation into cancer in Norfolk (EPIC-Norfolk) Prospective Population Study. Circulation 2007; 116: 2694-2701. (Pubitemid 350291241)
8. Bagatell CJ, Bremner WJ. Androgen and progestagen effects on plasma lipids. Prog Cardiovasc Dis 1995; 38: 255-271.
9. Yasui T, Uemura H, Irahara M, Arai M, Kojimahara N, Okabe R et al. Associations of endogenous sex hormones and sex hormone-binding globulin with lipid profiles in aged Japanese men and women. Clin Chim Acta 2008; 398: 43-47.
10. Handa K, Ishii H, Kono S, Shinchi K, Imanishi K, Mihara H et al. Behavioral correlates of plasma sex hormones and their relationships with plasma lipids and lipoproteins in Japanese men. Atherosclerosis 1997; 130: 37-44. (Pubitemid 27158027)
11. Fukai S, Akishita M, Miyao M, Ishida K, Toba K, Ouchi Y. Age-related changes in plasma androgen levels and their associa¬tion with cardiovascular risk factors in male Japanese office workers. Geriatr Gerontol Int 2010; 10: 32-39.
12. Katabami T, Kato H, Asahina T, Hinohara S, Shin T, Kawata T et al. Serum free testosterone and metabolic syndrome in Japanese men. Endocr J 2010; 57: 533-539.
13. Vermeulen A, Verdonck L, Kaufman JM. A critical evaluation of simple methods for the estimation of free testosterone in serum. J Clin Endocrinol Metab 1999; 84: 3666-3672. (Pubitemid 30645223)
14. Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low-density lipoprotein cholesterol in plas¬ma, without use of preparative ultracentrifuge. Clin Chem 1972; 18: 499-502.
15. Zilversmit DB. Atherogenic nature of triglycerides, postpran¬dial lipidemia, and triglyceride-rich remnant lipoproteins. Clin Chem 1995; 41: 153-158.
16. Lichtenstein MJ, Yarnell JW, Elwood PC, Beswick AD, Sweetnam PM, Marks V et al. Sex hormones, insulin, lipids, and prevalent ischemic heart disease. Am J Epidemiol 1987; 126: 647-657. (Pubitemid 17142236)
17. Barrett-Connor E, Khaw KT. Endogenous sex hormones and cardiovascular disease in men. A prospective population-based study. Circulation 1988; 78: 539-545.
18. Khaw KT, Barrett-Connor E. Endogenous sex hormones, high density lipoprotein cholesterol and other lipoprotein fractions in men. Arterioscler Thromb 1991; 11: 489-494.
19. Yarnell JW, Beswick AD, Sweetnam PM, Riad-Fahmy D. Endogenous sex hormones and ischemic heart disease in men. The Caerphilly prospective study. Arterioscler Thromb 1993; 13: 517-520. (Pubitemid 23107124)
20. Agledahl I, Skjaerpe PA, Hansen JB, Svartberg J. Low serum testosterone in men is inversely associated with non-fasting serum triglycerides: the Tromsø study. Nutr Metab Cardiovasc Dis 2008; 18: 256-262. (Pubitemid 351707613)
21. Freedman DS, O'Brien TR, Flanders WD, DeStefano F, Barboriak JJ. Relation of serum testosterone levels to high density lipoprotein cholesterol and other characteristics in men. Arterioscler Thromb 1991; 11: 307-315.
22. Gyllenborg J, Rasmussen SL, Borch-Johnsen K, Heitmann BL, Skakkebaek NE, Juul A. Cardiovascular risk factors in men: the role of gonadal steroids and sex hormone-binding globulin. Metabolism 2001; 50: 882-888. (Pubitemid 32755003)
23. Bataille V, Perret B, Evans A, Amouyel P, Arveiler D, Ducimetière P et al. Sex hormone-binding globulin is a major determinant of the lipid profiles: the PRIME study. Athero¬sclerosis 2005; 179: 369-373. (Pubitemid 40364633)
24. Lapauw B, Ouwens M, 't Hart LM, Wuyts B, Holst JJ, T'Sjoen G et al. Sex steroids affect triglyceride handling, glucose-dependent insulinotropic popypeptide, and insulin sensitiv¬ity. Diabet Care 2010; 33: 1831-1833.
25. Tsai EC, Boyko EJ, Leonetti DL, Fujimoto WY. Low serum testosterone level as a predictor of increased visceral fat in Japanese-American men. Int J Obes Relat Metab Disord 2000; 24: 485-491. (Pubitemid 30198102)
26. Adiels M, Taskinen MR, Packard C, Caslake MJ, Soro-Paavonen A, Westerbacka J et al. Overproduction of large VLDL particles is driven by increased liver fat content in man. Diabetologia 2006; 49: 755-765. (Pubitemid 43357551)
27. Oka R, Yagi K, Hifumi S, Miyamoto S, Mabuchi H, Yamagishi M et al. Postprandial triglyceridaemia in men with impaired fasting glucose, impaired glucose tolerance and diabetes. Diabet Med 2008; 25: 1008-1010.
28. Miller GJ, Wheeler MJ, Price SG, Beckles GL, Kirkwood BR, Carson DC. Serum high density lipoprotein subclasses, testosterone and sex-hormone binding globulin in Trinidadian men of African and Indian descent. Atherosclerosis 1985; 55: 251-258. (Pubitemid 15000528)
29. Van Pottelbergh I, Braeckman L, De Bacquer D, De Backer G, Kaufman JM. Differential contribution of testosterone and estradiol in the determination of cholesterol and lipoprotein profile in healthy middle-aged men. Atherosclerosis 2003; 166: 95-102. (Pubitemid 35449605)
30. Page ST, Mohr BA, Link CL, O'Donnell AB, Bremner WJ, McKinlay JB. Higher testosterone levels are associated with increased high-density lipoprotein cholesterol in men with cardiovascular disease: results from the Massachusetts Male Aging Study. Asian J Androl 2008; 10: 193-200. (Pubitemid 351337979)
31. Vaidya D, Dobs A, Gapstur SM, Golden SH, Hankinson A, Liu K et al. The association of endogenous sex hormones with lipoprotein subfraction profile in the Multi-Ethnic Study of Atherosclerosis. Metabolism 2008; 57: 782-790. (Pubitemid 351697909)
32. Gordon DJ, Probstfield JL, Garrison RJ, Neaton JD, Castelli WP, Knoke JD et al. High-density lipoprotein cholesterol and cardiovascular disease. Four prospective American studies. Circulation 1989; 79: 8-15. (Pubitemid 19043669)
33. Baigent C, Keech A, Kearney PM, Blackwell L, Buck G, Pollicino C et al. Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90056 participants in 14 randomised trials of statins. Lancet 2005; 366: 1267-1278.
34. Langsted A, Freiberg JJ, Nordestgaard BG. Fasting and nonfasting lipid levels: influence of normal food intake on lipids, lipoproteins, apolipoproteins, and cardiovascular risk prediction. Circulation 2008; 118: 2047-2056.
35. Zilversmit DB. Atherogenesis: a postprandial phenomenon. Circulation 1979; 60: 473-485. (Pubitemid 9254048)
36. Proctor SD, Mamo JC. Retention of fluorescent-labelled chylomicron remnants within the intima of the arterial wall-evidence that plaque cholesterol may be derived from post-prandial lipoprotein. Eur J Clin Invest 1998; 28: 497-503. (Pubitemid 28326416)
37. Nordestgaard BG, Benn M, Schnohr P, Tybjaerg-Hansen A. Nonfasting triglycerides and risk of myocardial infarction, ischemic heart disease, and death in men and women. JAMA 2007; 298: 299-308. (Pubitemid 47080484)
38. Bansal S, Buring JE, Rifai N, Mora S, Sacks FM, Ridker PM. Fasting compared with nonfasting triglycerides and risk of cardiovascular events in women. JAMA 2007; 298: 309-316. (Pubitemid 47080485)
39. Dai WS, Kuller LH, LaPorte RE, Gutai JP, Falvo-Gerard L, Caggiula A. The epidemiology of plasma testosterone levels in middle-aged men. Am J Epidemiol 1981; 114: 804-816. (Pubitemid 12246669)
40. Lu CC, Jiann BP, Sun CC, Lam HC, Chu CH, Lee JK. Association of glycemic control with risk of erectile dysfunction in men with type 2 diabetes. J Sex Med 2009; 6: 1719-1728.
41. Wall JR, Jarrett RJ, Zimmet PZ, Bailes M, Ramage CM. Fall in plasma-testosterone levels in normal male subjects in response to an oral glucose load. Lancet 1973; 1: 967-968.
42. Oka R, Kobayashi J, Miura K, Nagasawa S, Moriuchi T, Hifumi S et al. Difference between fasting and nonfasting triglycer-idemia; the influence of waist circumference. J Atheroscler Thromb 2009; 16: 633-640.