Antioxidant and cytotoxic properties of an aqueous extract from the Argentinean plant Hedeoma multiflorum

Pharmaceutical Biology

Volumn 49, Issue 6, 2011, Pages 633-639

  Dadé, Martín Miguel ^a   Schinella, Guillermo Raúl ^a,b   Fioravanti, Daniel Emilio ^a   Alfiotournier, Horacio ^a,b  

^a FACULTAD DE CIENCIAS MÉDICAS   (Argentina)

^b Universidad Provincial del Sudoeste   (Argentina)

Author keywords

apoptosis; Hedeoma multiflorum; lipid peroxidation; polymorphonuclear neutrophils; scavenger

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; 2,2' AZINOBIS(3 ETHYLBENZOTHIAZOLINE 6 SULFONIC ACID); 3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; 3,3' DIHEXYLOXACARBOCYANINE; ANTIOXIDANT; ASCORBIC ACID; CAFFEIC ACID; FERRIC ION; HEDEOMA MULTIFLORUM EXTRACT; ISOTHIOCYANIC ACID; LIPOCORTIN 5; PLANT EXTRACT; POLYPHENOL DERIVATIVE; PROPIDIUM IODIDE; REDUCING AGENT; SCAVENGER; UNCLASSIFIED DRUG; WATER;

ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARGENTINA; ARTICLE; BRAIN HOMOGENATE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DIPLOIDY; DRUG CYTOTOXICITY; DRUG MECHANISM; DRUG SCREENING; FLOW CYTOMETRY; FLUORESCENCE ANALYSIS; HEDEOMA; HEDEOMA MULTIFLORUM; HUMAN; HUMAN CELL; IN VITRO STUDY; LIPID PEROXIDATION; NONHUMAN; POLYMORPHONUCLEAR CELL; RAT;

HEDEOMA MULTIFLORUM; LAMIACEAE; RATTUS;

EID: 79955836918     PISSN: 13880209     EISSN: 17445116     Source Type: Journal    
DOI: 10.3109/13880209.2010.526949     Document Type: Article

References (36)

1. Aruoma OI, Bahorun T, Jen LS. (2003). Neuroprotection by bioactive components in medicinal and food plant extracts. Mutat Res, 544, 203-215. (Pubitemid 37487662)
2. Benzie IF, Strain JJ. (1996). Te ferric reducing ability of plasma (FRAP) as a measure of "antioxidant power": Te FRAP assay. Anal Biochem, 239, 70-76.
3. Chilvers ER, Cadwallader KA, Reed BJ, White JF, Condlife AM. (2000). Te function and fate of neutrophils at the infamed site: Prospects for therapeutic intervention. J R Coll Physicians Lond, 34, 68-74. (Pubitemid 30113753)
4. Cos P, Calomme M, Pieters L, Vlietinck AJ, Vanden Berghe D. (2000). Structure-activity relationship of favonoids as antioxidant and pro-oxidant compounds. In: Studies in Natural Products Chemistry, Vol. 22: 307-341. Ed. Rahman, A.U.,Elseiver, Amsterdam.
5. Del Rio D, Costa LG, Lean ME, Crozier A. (2010). Polyphenols and health: What compounds are involved? Nutr Metab Cardiovasc Dis, 20, 1-6.
6. Geronikaki AA, Gavalas AM. (2006). Antioxidants and infammatory disease: Synthetic and natural antioxidants with anti-infammatory activity. Comb Chem High Troughput Screen, 9, 425-442. (Pubitemid 44024700)
7. Goleniowski ME, Bongiovanni GA, Palacio L, Nuñez CO, Cantero JJ. (2006). Medicinal plants from the "Sierra de Comechingones", Argentina. J Ethnopharmacol, 107, 324-341. (Pubitemid 44344438)
8. Góngora L, Giner RM, Máñez S, Recio Mdel C, Schinella G, Ríos JL. (2002). Efects of cafeoyl conjugates of isoprenyl- hydroquinone glucoside and quinic acid on leukocyte function. Life Sci, 71, 2995-3004. (Pubitemid 35217876)
9. Gutteridge JM, Halliwell B. (1994). Oxygen-derived species: Teir relation to human disease and environmental stress. Environ Health Perspec, 102(Suppl 10), 5-12.
10. Hallett JM, Leitch AE, Riley NA, Dufn R, Haslett C, Rossi AG. (2008). Novel pharmacological strategies for driving infammatory cell apoptosis and enhancing the resolution of infammation. Trends Pharmacol Sci, 29, 250-257.
11. Halliwell B. (1999). Antioxidant defence mechanisms: From the beginning to the end (of the beginning). Free Radic Res, 31, 261-272. (Pubitemid 29452853)
12. Halliwell B. (2006). Phagocyte-derived reactive species: Salvation or suicide? Trends Biochem Sci, 31, 509-515. (Pubitemid 44279983)
13. Halliwell B. (2009). Te wanderings of a free radical. Free Radic Biol Med, 46, 531-542.
14. Homburg CH, de Haas M, von dem Borne AE, Verhoeven AJ, Reutelingsperger CP, Roos D. (1995). Human neutrophils lose their surface Fc gamma RIII and acquire Annexin V binding sites during apoptosis in vitro. Blood, 85, 532-540.
15. Javanmardi J, Stushnof C, Locke E, Vivanco JM. (2003). Antioxidant activity and total phenolic content of Iranian Ocimum accessions. Food Chem, 83, 547-550. (Pubitemid 37162807)
16. Juan ME, Wenzel U, Ruiz-Gutierrez V, Daniel H, Planas JM. (2006). Olive fruit extracts inhibit proliferation and induce apoptosis in HT-29 human colon cancer cells. J Nutr, 136, 2553-2557. (Pubitemid 44521612)
17. Kumar N, Shibata D, Helm J, Coppola D, Malafa M. (2007). Green tea polyphenols in the prevention of colon cancer. Frontiers in Bioscience, 12, 2309-2315.
18. Macho A, Hirsch T, Marzo I, Marchetti P, Dallaporta B, Susin SA, Zamzami N, Kroemer G. (1997). Glutathione depletion is an early and calcium elevation is a late event of thymocyte apoptosis. J Immunol, 158, 4612-4619. (Pubitemid 127483779)
19. Morel I, Abaléa V, Sergent O, Cillard P, Cillard J. (1998). Involvement of phenoxyl radical intermediates in lipid antioxidant action of myricetin in iron-treated rat hepatocyte culture. Biochem Pharmacol, 55, 1399-1404. (Pubitemid 28298520)
20. Mosmann T. (1983). Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J Immunol Methods, 65, 55-63. (Pubitemid 14203433)
21. Mower DA Jr, Peckham DW, Illera VA, Fishbaugh JK, Stunz LL, Ashman RF. (1994). Decreased membrane phospholipid packing and decreased cell size precede DNA cleavage in mature mouse B cell apoptosis. J Immunol, 152, 4832-4842. (Pubitemid 24139076)
22. Nicoletti I, Migliorati G, Pagliacci MC, Grignani F, Riccardi C. (1991). A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and fow cytometry. J Immunol Methods, 139, 271-279.
23. Pompella A, Maellaro E, Casini AF, Ferrali M, Ciccoli L, Comporti M. (1987). Measurement of lipid peroxidation in vivo: A comparison of diferent procedures. Lipids, 22, 206-211.
24. Rao YK, Geethangili M, Fang SH, Tzeng YM. (2007). Antioxidant and cytotoxic activities of naturally occurring phenolic and related compounds: A comparative study. Food Chem Toxicol, 45, 1770-1776. (Pubitemid 47102515)
25. + radical cation decolorization assay. Free Radic Biol Med, 26, 1231-1237. (Pubitemid 29262709)
26. Singleton VL, Rossi JA. (1965). Colorimetry of total phenolics with phospho-molybdic-phosphotungstic acid reagents. Am J Enol Viticul, 16, 144-158.
27. Schinella GR, Tournier HA, Máñez S, de Buschiazzo PM, Del Carmen Recio M, Ríos JL. (2007). Tiliroside and gnaphaliin inhibit human low density lipoprotein oxidation. Fitoterapia, 78, 1-6. (Pubitemid 44909361)
28. Slanis AC, Bulacio E. (2005). Hedeoma mandonianum (Lamiaceae) en Argentina. Bol Soc Argent Bol, 40, 3-4.
29. Spranger T, Finckh B, Fingerhut R, Kohlschütter A, Beisiegel U, Kontush A. (1998). How diferent constituents of human plasma and low density lipoprotein determine plasma oxidizability by copper. Chem Phys Lipids, 91, 39-52. (Pubitemid 28056879)
30. Toursarkissian M. (1980). In: Plantas Medicinales de la Argentina. Ed. H. Sur Buenos Aires 63-178.
31. Ulrich-Merzenich G, Zeitler H, Vetter H, Kraft K. (2009). Synergy research: Vitamins and secondary plant components in the maintenance of the redox-homeostasis and in cell signaling. Phytomedicine, 16, 2-16.
32. Viveros-Valdez E, Rivas-Morales C, Carranza-Rosales P, Mendoza S, Schmeda-Hirschmann G. (2008). Free radical scavengers from the Mexican herbal tea "poleo" (Hedeoma drummondii). z Naturforsch, C, J Biosci, 63, 341-346.
33. Ward C, Dransfeld I, Chilvers ER, Haslett C, Rossi AG. (1999). Pharmacological manipulation of granulocytes apoptosis: Potential therapeutic targets. Trends in Pharmacol Sci, 20, 503-509. (Pubitemid 30004023)
34. Wu Y, Yang L, Wang F, Wu X, Zhou C, Shi S, Mo J, Zhao Y. (2007). Hepatoprotective and antioxidative efects of total phenolics from Laggera pterodonta on chemical-induced injury in primary cultured neonatal rat hepatocytes. Food Chem Toxicol, 45, 1349-1355. (Pubitemid 47039266)
35. Yonathan M, Asres K, Assefa A, Bucar F. (2006). In vivo anti-infammatory and anti-nociceptive activities of Cheilanthes farinosa. J Ethnopharmacol, 108, 462-470. (Pubitemid 44693113)
36. Zielinska-Przyjemska M, Ignatowicz E. (2008). Citrus fruit favonoids infuence on neutrophil apoptosis and oxidative metabolism. Phytother Res, 22, 1557-1562.