-
1
-
-
33845965299
-
Inflammatory bowel disease: Is it really just another break in the wall?
-
DOI 10.1136/gut.2006.104182
-
Weber CR, Turner JR., Inflammatory bowel disease: is it really just another break in the wall? Gut. 2007; 56: 6-8. (Pubitemid 46044880)
-
(2007)
Gut
, vol.56
, Issue.1
, pp. 6-8
-
-
Weber, C.R.1
Turner, J.R.2
-
2
-
-
0035019636
-
Proteinase-activated receptors
-
Macfarlane SR, Seatter MJ, Kanke T, et al. Proteinase-activated receptors. Pharmacol Rev. 2001; 53: 245-282. (Pubitemid 32476117)
-
(2001)
Pharmacological Reviews
, vol.53
, Issue.2
, pp. 245-282
-
-
Macfarlane, S.R.1
Seatter, M.J.2
Kanke, T.3
Hunter, G.D.4
Plevin, R.5
-
3
-
-
19544392708
-
Clinical relevance of proteinase activated receptors (PARs) in the gut
-
DOI 10.1136/gut.2004.048876
-
Vergnolle N., Clinical relevance of proteinase activated receptors (PARs) in the gut. Gut. 2005; 54: 867-874. (Pubitemid 40732107)
-
(2005)
Gut
, vol.54
, Issue.6
, pp. 867-874
-
-
Vergnolle, N.1
-
5
-
-
34548205756
-
2+ signaling in mouse lung alveolar epithelial cells
-
DOI 10.1016/j.lfs.2007.06.026, PII S0024320507004699
-
Ando S, Otani H, Yagi Y, et al. Protease-activated receptor 4-mediated Ca2+ signaling in mouse lung alveolar epithelial cells. Life Sci. 2007; 81: 794-802. (Pubitemid 47332511)
-
(2007)
Life Sciences
, vol.81
, Issue.10
, pp. 794-802
-
-
Ando, S.1
Otani, H.2
Yagi, Y.3
Kawai, K.4
Araki, H.5
Nakamura, T.6
Fukuhara, S.7
Inagaki, C.8
-
6
-
-
1642574390
-
4) in the rat colon
-
DOI 10.1136/gut.2003.021899
-
Mule F, Pizzuti R, Capparelli A, et al. Evidence for the presence of functional protease activated receptor 4 (PAR4) in the rat colon. Gut. 2004; 53: 229-234. (Pubitemid 38125510)
-
(2004)
Gut
, vol.53
, Issue.2
, pp. 229-234
-
-
Mule, F.1
Pizzuti, R.2
Capparelli, A.3
Vergnolle, N.4
-
7
-
-
67649990850
-
Luminal cathepsin G and protease-activated receptor 4. A duet involved in alterations of the colonic epithelial barrier in ulcerative colitis
-
Dabek M, Ferrier L, Roka R, et al. Luminal cathepsin G and protease-activated receptor 4. A duet involved in alterations of the colonic epithelial barrier in ulcerative colitis. Am J Pathol. 2009; 175: 207-214.
-
(2009)
Am J Pathol.
, vol.175
, pp. 207-214
-
-
Dabek, M.1
Ferrier, L.2
Roka, R.3
-
8
-
-
0034629468
-
Cathepsin G activates protease-activated receptor-4 in human platelets
-
DOI 10.1074/jbc.275.10.6819
-
Sambrano GR, Huang W, Faruqi T, et al. Cathepsin G activates protease-activated receptor-4 in human platelets. J Biol Chem. 2000; 275: 6819-6823. (Pubitemid 30146221)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.10
, pp. 6819-6823
-
-
Sambrano, G.R.1
Huang, W.2
Faruqi, T.3
Mahrus, S.4
Craik, C.5
Coughlin, S.R.6
-
9
-
-
0037592155
-
Neutrophil cathepsin G promotes detachment-induced cardiomyocyte apoptosis via a protease-activated receptor-independent mechanism
-
DOI 10.1074/jbc.M302718200
-
Sabri A, Alcott SG, Elouardighi H, et al. Neutrophil cathepsin G promotes detachment-induced cardiomyocyte apoptosis via a protease-activated receptor-independent mechanism. J Biol Chem. 2003; 278: 23944-23954. (Pubitemid 36830223)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.26
, pp. 23944-23954
-
-
Sabri, A.1
Alcott, S.G.2
Elouardighi, H.3
Pak, E.4
Derian, C.5
Andrade-Gordon, P.6
Kinnally, K.7
Steinberg, S.F.8
-
10
-
-
27644557524
-
Neutrophils and the kallikrein-kinin system in proteinase-activated receptor 4-mediated inflammation in rodents
-
DOI 10.1038/sj.bjp.0706371, PII 0706371
-
Houle S, Papez MD, Ferazzini M, et al. Neutrophils and the kallikrein-kinin system in proteinase-activated receptor 4-mediated inflammation in rodents. Br J Pharmacol. 2005; 146: 670-678. (Pubitemid 41573618)
-
(2005)
British Journal of Pharmacology
, vol.146
, Issue.5
, pp. 670-678
-
-
Houle, S.1
Papez, M.D.2
Ferazzini, M.3
Hollenberg, M.D.4
Vergnolle, N.5
-
11
-
-
34247539019
-
A Pilot Study of Fecal Serine-Protease Activity: A Pathophysiologic Factor in Diarrhea-Predominant Irritable Bowel Syndrome
-
DOI 10.1016/j.cgh.2006.12.004, PII S1542356506012948
-
Roka R, Rosztoczy A, Leveque M, et al. A pilot study of fecal serine-protease activity: a pathophysiologic factor in diarrhea-predominant irritable bowel syndrome. Clin Gastroenterol Hepatol. 2007; 5: 550-555. (Pubitemid 46660764)
-
(2007)
Clinical Gastroenterology and Hepatology
, vol.5
, Issue.5
, pp. 550-555
-
-
Roka, R.1
Rosztoczy, A.2
Leveque, M.3
Izbeki, F.4
Nagy, F.5
Molnar, T.6
Lonovics, J.7
Garcia-Villar, R.8
Fioramonti, J.9
Wittmann, T.10
Bueno, L.11
-
12
-
-
42549168553
-
Increased faecal serine protease activity in diarrhoeic IBS patients: A colonic lumenal factor impairing colonic permeability and sensitivity
-
Gecse K, Roka R, Ferrier L, et al. Increased faecal serine protease activity in diarrhoeic IBS patients: a colonic lumenal factor impairing colonic permeability and sensitivity. Gut. 2008; 57: 591-599.
-
(2008)
Gut.
, vol.57
, pp. 591-599
-
-
Gecse, K.1
Roka, R.2
Ferrier, L.3
-
13
-
-
4444377666
-
2 activation alters colonic paracellular permeability in mice via IFN-γ-dependent and -independent pathways
-
DOI 10.1113/jphysiol.2004.061721
-
Cenac N, Chin AC, Garcia-Villar R, et al. PAR2 activation alters colonic paracellular permeability in mice via IFN-gamma-dependent and -independent pathways. J Physiol. 2004; 558: 913-925. (Pubitemid 39199112)
-
(2004)
Journal of Physiology
, vol.558
, Issue.3
, pp. 913-925
-
-
Cenac, N.1
Chin, A.C.2
Garcia-Villar, R.3
Salvador-Cartier, C.4
Ferrier, L.5
Vergnolle, N.6
Buret, A.G.7
Fioramonti, J.8
Bueno, L.9
-
14
-
-
33845995125
-
Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn's disease
-
DOI 10.1136/gut.2006.094375
-
Zeissig S, Burgel N, Gunzel D, et al. Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn's disease. Gut. 2007; 56: 61-72. (Pubitemid 46044890)
-
(2007)
Gut
, vol.56
, Issue.1
, pp. 61-72
-
-
Zeissig, S.1
Burgel, N.2
Gunzel, D.3
Richter, J.4
Mankertz, J.5
Wahnschaffe, U.6
Kroesen, A.J.7
Zeitz, M.8
Fromm, M.9
Schulzke, J.-D.10
-
15
-
-
0032958705
-
Altered tight junction structure contributes to the impaired epithelial barrier function in ulcerative colitis
-
DOI 10.1016/S0016-5085(99)70126-5
-
Schmitz H, Barmeyer C, Fromm M, et al. Altered tight junction structure contributes to the impaired epithelial barrier function in ulcerative colitis. Gastroenterology. 1999; 116: 301-309. (Pubitemid 29055352)
-
(1999)
Gastroenterology
, vol.116
, Issue.2
, pp. 301-309
-
-
Schmitz, H.1
Barmeyer, C.2
Fromm, M.3
Runkel, N.4
Foss, H.-D.5
Bentzel, C.J.6
Riecken, E.-O.7
Schulzke, J.-D.8
-
16
-
-
2142813761
-
A porous defense: The leaky epithelial barrier in intestinal disease
-
DOI 10.1038/labinvest.3700050
-
Clayburgh DR, Shen L, Turner JR., A porous defense: the leaky epithelial barrier in intestinal disease. Lab Invest. 2004; 84: 282-291. (Pubitemid 41656483)
-
(2004)
Laboratory Investigation
, vol.84
, Issue.3
, pp. 282-291
-
-
Clayburgh, D.R.1
Shen, L.2
Turner, J.R.3
-
17
-
-
26244450671
-
Myosin light chain kinase is involved in lipopolysaccharide-induced disruption of colonic epithelial barrier and bacterial translocation in rats
-
Moriez R, Salvador-Cartier C, Theodorou V, et al. Myosin light chain kinase is involved in lipopolysaccharide-induced disruption of colonic epithelial barrier and bacterial translocation in rats. Am J Pathol. 2005; 167: 1071-1079. (Pubitemid 41416259)
-
(2005)
American Journal of Pathology
, vol.167
, Issue.4
, pp. 1071-1079
-
-
Moriez, R.1
Salvador-Cartier, C.2
Theodorou, V.3
Fioramonti, J.4
Eutamene, H.5
Bueno, L.6
-
18
-
-
0020051148
-
Measurement of cutaneous inflammation: Estimation of neutrophil content with an enzyme marker
-
Bradley PP, Priebat DA, Christensen RD, et al. Measurement of cutaneous inflammation: estimation of neutrophil content with an enzyme marker. J Invest Dermatol. 1982; 78: 206-209. (Pubitemid 12171880)
-
(1982)
Journal of Investigative Dermatology
, vol.78
, Issue.3
, pp. 206-209
-
-
Bradley, P.P.1
Priebat, D.A.2
Christensen, R.D.3
Rothstein, G.4
-
19
-
-
0036840275
-
Induction of intestinal inflammation in mouse by activation of proteinase-activated receptor-2
-
Cenac N, Coelho AM, Nguyen C, et al. Induction of intestinal inflammation in mouse by activation of proteinase-activated receptor-2. Am J Pathol. 2002; 161: 1903-1915. (Pubitemid 35265547)
-
(2002)
American Journal of Pathology
, vol.161
, Issue.5
, pp. 1903-1915
-
-
Cenac, N.1
Coelho, A.-M.2
Nguyen, C.3
Compton, S.4
Andrade-Gordon, P.5
MacNaughton, W.K.6
Wallace, J.L.7
Hollenberg, M.D.8
Bunnett, N.W.9
Garcia-Villar, R.10
Bueno, L.11
Vergnolle, N.12
-
20
-
-
85047689926
-
A role for proteinase-activated receptor-1 in inflammatory bowel diseases
-
DOI 10.1172/JCI200421689
-
Vergnolle N, Cellars L, Mencarelli A, et al. A role for proteinase-activated receptor-1 in inflammatory bowel diseases. J Clin Invest. 2004; 114: 1444-1456. (Pubitemid 40385575)
-
(2004)
Journal of Clinical Investigation
, vol.114
, Issue.10
, pp. 1444-1456
-
-
Vergnolle, N.1
Cellars, L.2
Mencarelli, A.3
Rizzo, G.4
Swaminathan, S.5
Beck, P.6
Steinhoff, M.7
Andrade-Gordon, P.8
Bunnett, N.W.9
Hollenberg, M.D.10
Wallace, J.L.11
Cirino, G.12
Fiorucci, S.13
-
21
-
-
0036797590
-
Pepducin-based intervention of thrombin-receptor signaling and systemic platelet activation
-
DOI 10.1038/nm760
-
Covic L, Misra M, Badar J, et al. Pepducin-based intervention of thrombin-receptor signaling and systemic platelet activation. Nat Med. 2002; 8: 1161-1165. (Pubitemid 35175972)
-
(2002)
Nature Medicine
, vol.8
, Issue.10
, pp. 1161-1165
-
-
Covic, L.1
Misra, M.2
Badar, J.3
Singh, C.4
Kuliopulos, A.5
-
22
-
-
0033672942
-
Molecular physiology and pathophysiology of tight junctions. IV. Regulation of tight junctions by extracellular stimuli: Nutrients, cytokines, and immune cells
-
Nusrat A, Turner JR, Madara JL., Molecular physiology and pathophysiology of tight junctions. IV. Regulation of tight junctions by extracellular stimuli: nutrients, cytokines, and immune cells. Am J Physiol Gastrointest Liver Physiol. 2000; 279: G851-857.
-
(2000)
Am J Physiol Gastrointest Liver Physiol
, vol.279
-
-
Nusrat, A.1
Turner, J.R.2
Madara, J.L.3
-
23
-
-
33745193296
-
Myosin light chain phosphorylation regulates barrier function by remodeling tight junction structure
-
DOI 10.1242/jcs.02915
-
Shen L, Black ED, Witkowski ED, et al. Myosin light chain phosphorylation regulates barrier function by remodeling tight junction structure. J Cell Sci. 2006; 119: 2095-2106. (Pubitemid 43904964)
-
(2006)
Journal of Cell Science
, vol.119
, Issue.10
, pp. 2095-2106
-
-
Shen, L.1
Black, E.D.2
Witkowski, E.D.3
Lencer, W.I.4
Guerriero, V.5
Schneeberger, E.E.6
Turner, J.R.7
-
24
-
-
30944443377
-
Epithelial myosin light chain kinase expression and activity are upregulated in inflammatory bowel disease
-
DOI 10.1038/labinvest.3700373, PII 3700373
-
Blair SA, Kane SV, Clayburgh DR, et al. Epithelial myosin light chain kinase expression and activity are upregulated in inflammatory bowel disease. Lab Invest. 2006; 86: 191-201. (Pubitemid 43117598)
-
(2006)
Laboratory Investigation
, vol.86
, Issue.2
, pp. 191-201
-
-
Blair, S.A.1
Kane, S.V.2
Clayburgh, D.R.3
Turner, J.R.4
|