Repair of long bone defects with demineralized bone matrix and autogenous bone composite

Indian Journal of Orthopaedics

Volumn 45, Issue 3, 2011, Pages 226-230

  Ozdemir, Mehmet T ^a   Kir, Mustafa Ç ^b  

^a Department of Dermatology   (Turkey)

^b Istanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Education and Research Hospital   (Turkey)

Author keywords

bone defect; bone graft; Bone healing; fracture union

Indexed keywords

EID: 79955822889     PISSN: 00195413     EISSN: 19983727     Source Type: Journal    
DOI: 10.4103/0019-5413.80040     Document Type: Article

References (27)

1. Einhorn TA, Lane JM, Burstein AH, Kopman CR, Vigorita VJ. The healing of segmental bone defects induced by demineralized bone matrix. A radiographic and biomechanical study. J Bone Joint Surg Am 1984;66:274-9. (Pubitemid 14150394)
2. Bigham AS, Dehghani SN, Shafiei Z, Torabi Nezhad S. Xenogenic demineralized bone matrix and fresh autogenous cortical bone effects on experimental bone healing: Radiological, histopathological and biomechanical evaluation. J Orthop Traumatol 2008;9:73-80.
3. Chakkalakal DA, Strates BS, Mashoof AA, Garvin KL, Novak JR, Fritz ED, et al. Repair of segmental bone defects in the rat: An experimental model of human fracture healing. Bone 1999;25:321-32. (Pubitemid 29406058)
4. Edwards JT, Diegmann MH, Scarborough NL. Osteoinduction of human demineralized bone, osteoinduction in a rat model. Clin Orthop Relat Res 1998;357:219-28. (Pubitemid 29022452)
5. Rabie AB, Deng YM, Samman N, Hägg U. The effect of demineralized bone matrix on the healing of intramembranous bone grafts in the rabbit skull defects. J Dent Res 1996; 75:1045-51. (Pubitemid 32763592)
6. Yasko AW, Lane JM, Fellinger EJ, Rosen V, Wozney JM, Wang EA. The healing of segmental bone defects induced by recombinant bone morphogenetic protein (rhBMP-2). A radiographic, histological and biomechanical study in rats. J Bone Joint Surg Am 1992;74:659-70.
7. Bolander ME, Balian G. The use of demineralized bone matrix in the repair of segmental defects. Augmentation with extracted matrix proteins and a comparison with autologous grafts. J Bone Joint Surg Am 1986;68:1264-74. (Pubitemid 17179000)
8. Chakkalakal DA, Strates BS, Garvin KL, Novak JR, Fritz ED, Mollner TJ, et al. Demineralized bone matrix as a biological scaffold for bone repair. Tissue Eng 2001;7:161-77. (Pubitemid 32295151)
9. Cook SD, Baffes GC, Wolfe MW, Sampath TK, Rueger DC, Whitecloud TS 3rd. The effect of recombinant human osteogenic protein-1 on healing of large segmental bone defects. J Bone Joint Surg Am 1994;76:827-38. (Pubitemid 24213211)
10. Gebhart M, Lane J. A radiographical and biomechanical study of demineralized bone matrix implanted into a bone defect of rat femurs with and without bone marrow. Acta Orthop Belg 1991;57:130-43.
11. Rabie AB, Wong RW, Hagg U. Composite autogenous bone and demineralized bone matrices used to repair defects in the parietal bone of rabbits. Br J Oral Maxillofac Surg 2000; 38:565-70.
12. Tiedeman JJ, Garvin KL, Kile TA, Connolly JF. The role of composite, demineralized bone matrix and bone marrow in the treatment of osseous defects. Orthopedics 1995;18:1153-8.
13. Yang CY, Simmons DJ, Lozano R. The healing of grafts combining freeze dried and demineralized allogenic bone in rabbits. Clin Orthop Relat Res 1994;298:286-95. (Pubitemid 24023621)
14. Urrutia J, Thumm N, Apablaza D, Pizarro F, Zylberberg A, Quezada F. Autograft versus allograft with or without demineralized bone matrix in posterolateral lumbar fusion in rabbits. Laboratory investigation. J Neurosurg Spine 2008;9:84-9. (Pubitemid 351948781)
15. Turner TM, Urban RM, Hall DJ, Infanger S, Gitelis S, Petersen DW, et al. Osseous healing using injectable calcium sulfatebased putty for the delivery of demineralized bone matrix and cancellous bone chips. Orthopedics 2003;26:s571-5. (Pubitemid 36626258)
16. Oakes DA, Lee CC, Lieberman JR. An evaluation of human demineralized bone matrices in a rat femoral defect model. Clin Orthop Relat Res 2003;413:281-90. (Pubitemid 38063322)
17. Bostrom M, Lane JM, Tomin E, Browne M, Berberian W, Turek T, et al. Use of bone morphogenetic protein 2 in the rabbit ulnar nonunion model. Clin Orthop Relat Res 1996;327:272-82. (Pubitemid 26174996)
18. Reddi AH, Huggins C. Biochemical sequences in the transformation of normal fibroblasts in adolescent rats. Proc Natl Acad Sci U S A 1972;69:1601-5.
19. Lane JM, Yasko AW, Tomin E, Cole BJ, Waller S, Browne M, et al. Bone marrow and recombinant human bone morphogenetic protein-2 in osseous repair. Clin Orthop Relat Res 1999;361:216-27. (Pubitemid 29169812)
20. Markel MD, Morin RL, Wikenheiser MA, Lewallen DG, Chao EY. Quantitative CT for the evaluation of bone healing. Calcif Tissue Int 1991;49:427-32.
21. Feighan JE, Davy D, Prewett AB, Stevenson S. Induction of bone by a demineralized bone matrix gel. A study in a rat femoral defect model. J Orthop Res 1995;13:881-91. (Pubitemid 26032919)
22. Wittbjer J, Palmer B, Rohlin M, Thorngren KG. Osteogenic activity in composite rafts of demineralized compact bone and marrow. Clin Orthop Relat Res 1983;173:229-38.
23. Gepstein R, Weiss RE, Hallel T. Bridging large defects in bone by demineralized bone matrix in the form of a powder: A radiographical, histological and radioisotope uptake study in rats. J Bone Joint Surg Am 1987;69:984-92. (Pubitemid 18004693)
24. Solheim E, Pinholt EM, Andersen R, Bang G, Sudmann E. The effect of a composite of polyorthoester and demineralized bone on healing of large segmental defects of the radius in rats. J Bone Joint Surg Am 1992;74:1456-63. (Pubitemid 23046762)
25. Zhang M, Powers RM, Wolfinbarger L. Quantitative assessment of osteoinductivity of human demineralized bone matrix. J Periodontol 1997;68:1076-84. (Pubitemid 127513674)
26. Winn SR, Uludag H, Hollingery JO. Carrier systems for bone morphogenetic proteins. Clin Orthop Relat Res 1999;367: S95-107.
27. Martin GJ Jr, Boden SD, Titus L, Scarborough NL. New formulations of demineralized bone matrix as a more effective graft alternative in experimental posterolateral lumbar spine arthrodesis. Spine (Phila Pa 1976) 1999;24:637-45. (Pubitemid 29162905)