Correlation of haloperidol levels between saliva and plasma of acutely ill schizophrenic patients

Clinical Biochemistry

Volumn 44, Issue 8-9, 2011, Pages 675-680

  Jain, Tarun ^a   Bhandari, Anil ^a   Ram, Veerma ^a   Sharma, Sanjay ^a   Parakh, Manish ^b   Parakh, Mahaveer Chand ^b  

^a Jodhpur National University   (India)

^b DR S N MEDICAL COLLEGE   (India)

Author keywords

Clinical monitoring; Haloperidol saliva: plasma correlation; Non invasive monitoring; Salivary haloperidol levels

Indexed keywords

ACETIC ACID; ACETONITRILE; HALOPERIDOL; WATER;

ADULT; AGED; ARTICLE; CORRELATION ANALYSIS; CRITICALLY ILL PATIENT; DRUG BLOOD LEVEL; DRUG SALIVA LEVEL; FEMALE; FLOW RATE; HUMAN; MAJOR CLINICAL STUDY; MALE; MENTAL PATIENT; MONITORING; PH; PLASMA; PRIORITY JOURNAL; REVERSED PHASE LIQUID CHROMATOGRAPHY; SALIVA; SCHIZOPHRENIA; STEADY STATE; ULTRAVIOLET RADIATION;

ADOLESCENT; ADULT; AGED; HALOPERIDOL; HUMANS; MIDDLE AGED; MOLECULAR STRUCTURE; SALIVA; SCHIZOPHRENIA; YOUNG ADULT;

EID: 79955803299     PISSN: 00099120     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clinbiochem.2011.03.135     Document Type: Article

References (26)

1. Horning M.G., Brown L., Nowlin J., Lertratanangkoon K., Kellaway P., Zion T.E. Use of saliva in therapeutic drug monitoring. Clin Chem 1977, 23:157-164.
2. Drobitch R.K., Svensson C.K. Therapeutic drug monitoring in saliva an update. Clin Pharmacokinet 1992, 23:365-379.
3. Liu H., Delgado M.R. Therapeutic drug concentration monitoring using saliva samples focus on anticonvulsants. Clin Pharmacokinet 1999, 36:453-470.
4. Aps J.K., Martens L.C. Review: the physiology of saliva and transfer of drugs into saliva. Forensic Sci Int 2005, 150:119-131.
5. Miller S.M. Saliva testing-a non-traditional diagnostic tool. Clin Lab Sci 1994, 7:39-44.
6. Dasgupta A. Clinical utility of free drug monitoring. Clin Chem Lab Med 2002, 40:986-993.
7. May P.R., Putten T.V., Jenden D.J., Cho A.K. Test dose response in schizophrenia. Arc Gen Psychiatry 1978, 35:1091-1097.
8. Yamazumi S., Miura S. HPL concentrations in saliva and serum: determination by radioimmunoassay method. Int Pharmacopsychiatry 1981, 16:174-183.
9. DiGregorio G.J., Piraino A.J., Ruch E. Diazepam concentrations in paratoid saliva, mixed saliva, and plasma. Clin Pharmacol Ther 1978, 24:720-725.
10. Lena B., Bastable M. The reliability of salivary lithium estimation in children. IRCS J Med Sci 1978, 6:280.
11. Zohar J., Birmaher B., Schoenfeld H., Belmaker R.H. Salivary and blood levels of neuroleptics during outpatient maintenance treatment. Isr J Psychiatry Relat Sci 1986, 23:123-128.
12. Katzung B.G. Antipsychotic agents and lithium. Basic and clinical pharmacology 2001, The McGraw Hill Companies, USA. Third.
13. Zhang G., Terry A.V., Barlett M.G. Bioanalytical methods for the determination of antipsychotic drugs. Biomed Chromatogre 2008, 22:671-687.
14. Lawson G.M. Monitoring of serum HPL. M C P 1994, 69:189-190.
15. Gilman A.G., Rall T.W., Nies A.S., Taylor P. Goodman and Gilman's the pharmacological basis of therapeutics 1990, 1683. Pergamon Press, New York. 8th.
16. Eilers R. Therapeutic drug monitoring for the treatment of psychiatric disorders clinical use and cost effectiveness. C P 1995, 29:442-450.
17. Kudo S., Ishizaki T. Pharmacokinetics of HPL: an update. C P 1999, 435-456.
18. Noriyasu T., Kenji E., Kenji U., Yamaguchi M., Yasuo N. Correlation of HPL levels between submandibular saliva and brain in the rat. Arch Oral Biol 2006, 51:567-572.
19. Dysken M.W., Johnson S.B., Holden L., et al. HPL and reduced HPL in saliva and blood. J Clin Psychopharmacol 1992, 12:186-190.
20. Titier K., Bouchet S., Pehourcq F., Moore N., Molimard M. High-performance liquid chromatographic method with diode array detection to identify and quantify atypical antipsychotics and HPL in plasma after overdose. J Chromatogr B 2003, 788:179-185.
21. Kirchherr H., Kuhn-Velten W.N. Quantitative determination of forty-eight antidepressants and antipsychotics in human serum by HPLC tandem mass spectrometry: a multi-level, single-sample approach. J Chromatogr B 2006, 843:100-113.
22. Torre S.C., Martinez M.A., Almarza E. Determination of several psychiatric drugs in whole blood using capillary gas-liquid chromatography with nitrogen phosphorus detection: comparison of two solid phase extraction procedures. Forensic Sci Int 2005, 155:193.
23. Titier K.D., Cardone E., Abouelfath A., Moore N. Simplified high-performance liquid chromatographic method for determination of risperidone and 9-hydroxyrisperidone in plasma after overdose. J Chromatogr B 2002, 772:373.
24. Bianchetti G. P.L Morselli, Rapid and sensitive method for determination of HPL in human samples using nitrogen-phosphorus selective detection. J Chromatogr 1978, B153:203.
25. Guidance for industry: bioanalytical method validation. US Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research, Rockville (2001).
26. Kornhuber J., Schultz A., Wiltfang J., et al. Persistence of HPL in human brain tissue. Am J Psychiatry 1999, 156(6):885-890.