Determination of several psychiatric drugs in whole blood using capillary gas-liquid chromatography with nitrogen phosphorus detection: Comparison of two solid phase extraction procedures

Forensic Science International

Volumn 155, Issue 2-3, 2005, Pages 193-204

  Sánchez De La Torre, Carolina ^a   Martínez, María A ^a   Almarza, Elena ^a  

^a Biology Section Apdo 863 E 41080   (Spain)

Author keywords

GC; Psychiatric drugs; Screening; Solid phase extraction; Systematic toxicological analysis

Indexed keywords

AMINOPHENAZONE; ANTIDEPRESSANT AGENT; CHLORPROMAZINE; CLOMETHIAZOLE; CLOTIAPINE; CLOZAPINE; CYCLIZINE; EPHEDRINE; FENFLURAMINE; FLUOXETINE; HALOPERIDOL; LEVOMEPROMAZINE; LIDOCAINE; MEPIVACAINE; METHADONE; MIRTAZAPINE; NEUROLEPTIC AGENT; NITROGEN; OLANZAPINE; OXPRENOLOL; PHOSPHORUS; PIRACETAM; PRAZEPAM; PRIMIDONE; PROPRANOLOL; THIOPENTAL; THIORIDAZINE; UNINDEXED DRUG; VENLAFAXINE; VILOXAZINE;

ACCURACY; ARTICLE; CAPILLARY GAS CHROMATOGRAPHY; CONCENTRATION (PARAMETERS); DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG SCREENING; HUMAN; LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; SENSITIVITY ANALYSIS; SIGNAL NOISE RATIO; SOLID PHASE EXTRACTION;

EID: 26844444188     PISSN: 03790738     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.forsciint.2004.12.007     Document Type: Article

References (28)

1. R.J. Baldessarini Drugs and the treatment of psychiatric disorders: depression and anxiety disorders J. Hardman L. Limbird A. Gilman Goodman & Gilman's The Pharmacological Basis of Therapeutics 10th ed. 2001 McGraw-Hill New York 447 450
2. J.P. Franke, and R.A. de Zeeuw Solid-phase extraction procedures in systematic toxicological analysis J. Chromatogr. B 713 1998 51 59
3. T.J. Good, and J.S. Andrews The use of bonded-phase extraction columns for rapid sample preparation of benzodiazepines and metabolites from serum for HPLC analysis J. Chromatogr. Sci. 19 1981 562 566
4. G. Musch, and D.L. Massart Isolation of basic drugs from plasma using solid phase extraction with cyanopropyl-bonded phase J. Chromatogr. 432 1988 209 222
5. B.K. Logan, D.T. Stafford, I.R. Tebbett, and C.M. Moore Rapid screening for 100 basic drugs and metabolites in urine using cation exchange solid phase extraction and high-performance liquid chromatography with diode array detection J. Anal. Toxicol. 14 1990 154 159
6. Bond Elut Certify Instruction Manual 1992 Varian Inc. Harbor City, CA
7. X.-H. Chen, J. Wijsbeek, J.-P. Franke, and R.A. de Zeeuw A single-column procedure on Bond Elut Certify for systematic toxicological analysis of drugs in plasma and urine J. Forensic Sci. 37 1992 61 71
8. M. Balíková Selective system of identification and determination of antidepressants and neuroleptics in serum or plasma by solid-phase extraction followed by high-performance liquid chromatography with photodiode-array detection in analytical toxicology J. Chromatogr. 58 1992 175 181
9. H. Tokunaga, K. Kudo, T. Imamura, N. Jitsufuchi, and T. Nagata Sreening of antipsychotic drugs by wide-bore capillary gas chromatography with nitrogen phosphorus detection - detection levels in plasma Jpn. J. Legal Med. 50 1996 196 202
10. R. de la Torre, J. Ortuño, J.A. Pascual, S. González, and J. Ballesta Quantitative determination of tricyclic antidepressants and their metabolites in plasma by solid phase extraction (Bond-Elut TCA) and separation by capillary gas chromatography with nitrogen-phosphorous detection Ther. Drug Monit. 20 1998 340 346
11. C. Kratzsch, F.T. Peters, T. Kraemer, A.A. Weber, and H.H. Maurer Screening, library-assisted identification and validated quantification of fifteen neuroleptics and three of their metabolites in plasma by liquid chromatography/mass spectrometry with atmospheric pressure chemical ionization J. Mass Spectrom. 38 2003 283 295
12. C. Frahnert, M.L. Rao, and K. Grasmäder Analysis of eighteen antidepressants, four atypical antipsychotics and active metabolites in serum by liquid chromatography: a simple tool for therapeutic drug monitoring J. Chromatogr. B 794 2003 35 47
13. I.R. Tebbett Rapid extraction of codeine and morphine in whole blood for HPLC Chromatographia 23 1987 377 378
14. C.M. Moore, and I.R. Tebbett Rapid extraction of anti-inflammatory drugs in whole blood for HPLC Forensic Sci. Int. 34 1987 155 158
15. R.J. Hughes, and M.D. Osselton Comparison of methods for the analysis of tricyiclic antidepressants in small whole blood samples J. Anal. Toxicol. 13 1989 163 168
16. X.-H. Chen, J.-P. Franke, J. Wijsbeek, and R.A. de Zeeuw Isolation of acidic, neutral, and basic drugs from whole blood using a single mixed-mode solid-phase extraction column J. Anal. Toxicol. 16 1992 351 355
17. X.-H. Chen, J.-P. Franke, J. Wijsbeek, and R.A. de Zeeuw Pitfalls and solutions in the development of a fully automated solid-phase extraction method for drug screening purposes in plasma and whole blood J. Anal. Toxicol. 17 1993 421 426
18. P.G.M. Zweipfenning, A.H.C.M. Wilderink, P. Horsthuis, J.-P. Franke, and R.A. de Zeeuw Toxicological analysis of whole blood samples by means of Bond Elut Certify columns by gas chromatography with nitrogen-phosphorus detection J. Chromatogr. A 674 1994 87 95
19. X.-H. Chen, J.-P. Franke, J. Wijsbeek, and R.A. de Zeeuw Determination of basic drugs extracted from biological matrices by means of solid-phase extraction and wide-bore capillary gas chromatography with nitrogen-phosphorus detection J. Anal. Toxicol. 18 1994 150 153
20. M.A. Martínez, C. Sánchez de la Torre, and E. Almarza Simultaneous determination of viloxazine, venlafaxine, imipramine, desipramine, sertraline, and amoxapine in whole blood: comparison of two extraction/clean-up procedures for capillary gas-liquid chromatography with nitrogen-phosphorus detection J. Anal. Toxicol. 26 2002 296 302
21. ® column J. Anal. Toxicol. 26 2002 325 332
22. M.A. Martínez, C. Sánchez de la Torre, and E. Almarza A comparative solid-phase extraction study for the simultaneous determination of fluoxetine, amitriptyline, nortriptyline, trimipramine, maprotiline, clomipramine, and trazodone in whole blood by capillary gas-liquid chromatography with nitrogen-phosphorus detection J. Anal. Toxicol. 27 2003 353 358
23. M.A. Martínez, C. Sánchez de la Torre, and E. Almarza A comparative solid-phase extraction study for the simultaneous determination of fluvoxamine, mianserin, doxepine, citalopram, paroxetine, and etoperidone in whole blood by capillary gas-liquid chromatography with nitrogen-phosphorus detection J. Anal. Toxicol. 28 2004 174 180
24. J. Breiter, R. Helger, and H. Lang Evaluation of column extraction: a new procedure for the analysis of drugs in body fluids Forensic Sci. 7 1976 131 140
25. B.K. Logan, and D.T. Stafford Liquid/solid extraction on diatomaceus earth for drug analysis in postmortem blood J. Forensic Sci. 34 1989 553 564
26. C. Lora-Tamayo, M.A. Rams, and J.M.R. Chacon Gas chromatographic data for 187 nitrogen-or phosfhorus containing drugs and metabolites of toxicological interest analysed on methyl silicone capillary columns J. Chromatogr. 374 1986 73 85
27. The International Association of Forensic Toxicologists, Therapeutic and Toxic Drugs Concentrations List (OnLine), August 2004, TIAFT, 1995-2004, Created and maintained by CBFT, Padova & San Patrignano, Rimini, Italy. http://www.tiaft.org/tmembers/.
28. A.H. Stead, and A. Moffat A collection of therapeutic, toxic and fatal blood drug concentration in man Hum. Toxicol. 3 1983 437 464