-
1
-
-
79955798348
-
-
National Diabetes Statistics [Last accessed 25 January 2011]
-
National Diabetes Statistics, 2007.Available from: http://diabetes.niddk. nih.gov/dm/pubs/statistics [Last accessed 25 January 2011]
-
(2007)
-
-
-
2
-
-
41349098117
-
An Albumin-Exendin-4 Conjugate Engages Central and Peripheral Circuits Regulating Murine Energy and Glucose Homeostasis
-
DOI 10.1053/j.gastro.2008.01.017, PII S0016508508000565
-
Baggio LL, Huang Q, Cao X, Drucker DJ.An albumin-exendin-4 conjugate engages central and peripheral circuits regulating murine energy and glucose homeostasis.Gastroenterology 2008;134:1137-47 (Pubitemid 351451971)
-
(2008)
Gastroenterology
, vol.134
, Issue.4
, pp. 1137-1147
-
-
Baggio, L.L.1
Huang, Q.2
Cao, X.3
Drucker, D.J.4
-
3
-
-
0036307610
-
The short half-life of glucagon-like peptide-1 in plasma does not reflect its long-lasting beneficial effects
-
Hui H, Farilla L, Merkel P, Perfetti R.The short half-life of glucagon like peptide-1 in plasma does not reflect its long-lasting beneficial effects.Eur J Endocrinol 2002;146:863-9 (Pubitemid 34705080)
-
(2002)
European Journal of Endocrinology
, vol.146
, Issue.6
, pp. 863-869
-
-
Hui, H.1
Farilla, L.2
Merkel, P.3
Perfetti, R.4
-
4
-
-
38549162147
-
Exenatide effects on diabetes, obesity, cardiovascular risk factors and hepatic biomarkers in patients with type 2 diabetes treated for at least 3 years
-
DOI 10.1185/030079907X253870
-
Klonoff DC, Buse JB, Nielsen LL, et al.Exenatide effects on diabetes, obesity, cardiovascular risk factors and hepatic biomarkers in patients with type 2 diabetes treated for at least three years.Curr Med Res Opin 2008;24:275-86 (Pubitemid 351160260)
-
(2008)
Current Medical Research and Opinion
, vol.24
, Issue.1
, pp. 275-286
-
-
Klonoff, D.C.1
Buse, J.B.2
Nielsen, L.L.3
Guan, X.4
Bowlus, C.L.5
Holcombe, J.H.6
Wintle, M.E.7
Maggs, D.G.8
-
5
-
-
34250829991
-
-
Amylin Pharmaceuticals, Eli Lilly, and Co Sept 2010
-
Amylin Pharmaceuticals, Eli Lilly, and Co.Byetta package insert.Sept 2010
-
Byetta Package Insert
-
-
-
7
-
-
59449101432
-
Liraglutide versus glimepiride monotherapy for type 2 diabetes (LEAD-3 Mono): A randomised, 52-week, phase III, double-blind, parallel-treatment trial
-
Garber A, Henry R, Ratner R, et al.Liraglutide versus glimepiride monotherapy for type 2 diabetes (LEAD-3 Mono): a randomised, 52-week, phase III, double-blind, parallel-treatment trial.Lancet 2009;373:473-81
-
(2009)
Lancet
, vol.373
, pp. 473-81
-
-
Garber, A.1
Henry, R.2
Ratner, R.3
-
8
-
-
77958045977
-
Liraglutide: A once daily human glucagon like peptide-1 analogue for type 2 diabetes mellitus
-
David Joffe.Liraglutide: a once daily human glucagon like peptide-1 analogue for type 2 diabetes mellitus.Am J Health Syst Pharm 2010;67:1326-36
-
(2010)
Am J Health Syst Pharm
, vol.67
, pp. 1326-36
-
-
Joffe, D.1
-
9
-
-
77950228684
-
Glucagon-like peptide-1 receptor agonists activate rodent thyroid C-cells causing calcitonin release and C-cell proliferation
-
Bjerre Knudsen L, Madsen LW, Andersen S, et al.Glucagon-like peptide-1 receptor agonists activate rodent thyroid C-cells causing calcitonin release and C-cell proliferation.Endocrinology 2010;151:1473-86
-
(2010)
Endocrinology
, vol.151
, pp. 1473-86
-
-
Bjerre Knudsen, L.1
Madsen, L.W.2
Andersen, S.3
-
10
-
-
45449105789
-
Safety and efficacy of sitagliptin in patients with type 2 diabetes and chronic renal insufficiency
-
DOI 10.1111/j.1463-1326.2008.00914.x
-
Chan JC, Scott R, Arjona Ferreira JC, et al.Safety and efficacy of sitagliptin in patients with type 2 diabetes and chronic renal insufficiency.Diabetes Obes Metab 2008;10:545-55 (Pubitemid 351850898)
-
(2008)
Diabetes, Obesity and Metabolism
, vol.10
, Issue.7
, pp. 545-555
-
-
Chan, J.C.N.1
Scott, R.2
Arjona Ferreira, J.C.3
Sheng, D.4
Gonzalez, E.5
Davies, M.J.6
Stein, P.P.7
Kaufman, K.D.8
Amatruda, J.M.9
Williams-Herman, D.10
-
11
-
-
42149194313
-
Glucose-lowering activity of the dipeptidyl peptidase-4 inhibitor saxagliptin in drug-naive patients with type 2 diabetes
-
DOI 10.1111/j.1463-1326.2008.00876.x
-
Rosenstock J, Sankoh S, List JF.Glucose-lowering activity of the dipeptidyl peptidase-4 inhibitor saxagliptin in drug-naive patients with type 2 diabetes.Diabetes Obes Metab 2008;10:376-86 (Pubitemid 351524285)
-
(2008)
Diabetes, Obesity and Metabolism
, vol.10
, Issue.5
, pp. 376-386
-
-
Rosenstock, J.1
Sankoh, S.2
List, J.F.3
-
12
-
-
77958540127
-
Vildagliptin: A review of its use in type 2 diabetes mellitus
-
Gm Keating.Vildagliptin: a review of its use in type 2 diabetes mellitus.Drugs 2010;70:2089-112
-
(2010)
Drugs
, vol.70
, pp. 2089-112
-
-
Keating, G.1
-
14
-
-
79955843010
-
-
Merck Pharmaceuticals.Onglyza (saxagliptin) prescribing information.revised and published Feb 2011
-
Merck Pharmaceuticals.Onglyza (saxagliptin) prescribing information.revised and published Feb 2011
-
-
-
-
15
-
-
79955820416
-
-
January 2009 [Last accessed 20 November 2010]
-
Fact Sheet Medisorb Microspheres Technology, January 2009.Available from: http://www.alkermes.com/media/42408/general%20medisorb% 20techonology%20fact%20sheet%20jan %202009%20-%20011409%20pdf [Last accessed 20 November 2010].
-
Fact Sheet Medisorb Microspheres Technology
-
-
-
16
-
-
0031040794
-
Tissue-specific expression of unique mRNAs that encode proglucagon- derived peptides or exendin 4 in the lizard
-
DOI 10.1074/jbc.272.7.4108
-
Chen YE, Drucker DJ.Tissue-specific expressions of unique mRNAs that encode proglucagon-derived peptides or exendin-4 in the lizard.J Biol Chem 1997;272:4108-15 (Pubitemid 27078475)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.7
, pp. 4108-4115
-
-
Chen, Y.E.1
Drucker, D.J.2
-
18
-
-
34249891874
-
Effects of once-weekly dosing of a long-acting release formulation of exenatide on glucose control and body weight in subjects with type 2 diabetes
-
DOI 10.2337/dc06-2375
-
Kim D, MacConell L, Zhuang D, et al.Effects of once-weekly dosing of a long-acting release formulation of exenatide on glucose control and body weight in subjects with type 2 diabetes.Diabetes Care 2007;30:1487-93 (Pubitemid 46871159)
-
(2007)
Diabetes Care
, vol.30
, Issue.6
, pp. 1487-1493
-
-
Kim, D.1
MacConell, L.2
Zhuang, D.3
Kothare, P.A.4
Trautmann, M.5
Fineman, M.6
Taylor, K.7
-
20
-
-
53249142132
-
Exenatide once weekly versus twice daily for the treatment of type 2 diabetes: A randomised open-label non-inferiority study
-
Drucker DJ, Buse JB, Taylor K, et al.; DURATION-1 Study Group.Exenatide once weekly versus twice daily for the treatment of type 2 diabetes: a randomised, open-label, non-inferiority study.Lancet 2008;372:1240-50
-
(2008)
Lancet
, vol.372
, pp. 1240-50
-
-
Drucker, D.J.1
Buse, J.B.2
Et Al., T.K.3
-
21
-
-
73549096393
-
Safety, tolerability, pharmacokinetics, and pharmacodynamics of exenatide once weekly in Japanese patients with type 2 diabetes
-
Iwamoto K, Nasu R, Yamamura A, et al.Safety, tolerability, pharmacokinetics, and pharmacodynamics of exenatide once weekly in Japanese patients with type 2 diabetes.Endocr J 2009;56:951-62
-
(2009)
Endocr J
, vol.56
, pp. 951-62
-
-
Iwamoto, K.1
Nasu, R.2
Yamamura, A.3
-
22
-
-
33646497453
-
Investigation of exenatide elimination and its in vivo and in vitro degredation
-
Copley K, McCowen K, Hiles R, et al.Investigation of exenatide elimination and its in vivo and in vitro degredation.Curr Drug Metab 2006;7:367-74
-
(2006)
Curr Drug Metab
, vol.7
, pp. 367-74
-
-
Copley, K.1
McCowen, K.2
Hiles, R.3
-
23
-
-
34548034895
-
Effect of renal impairment on the pharmacokinetics of exenatide
-
DOI 10.1111/j.1365-2125.2007.02890.x
-
Linnebjerg H, Kothare PA, Park S, et al.Effect of renal impairment on the pharmacokinetics of exenatide.Br J Clin Pharmacol 2007;64:317-27 (Pubitemid 47283860)
-
(2007)
British Journal of Clinical Pharmacology
, vol.64
, Issue.3
, pp. 317-327
-
-
Linnebjerg, H.1
Kothare, P.A.2
Park, S.3
Mace, K.4
Reddy, S.5
Mitchell, M.6
Lins, R.7
-
24
-
-
77953859640
-
Once weekly exenatide compared with insulin glargine titrated to target in patients with type 2 diabetes (DURATION-3): An open-label randomised trial
-
Diamant M, Van Gaal L, Stranks S, et al.Once weekly exenatide compared with insulin glargine titrated to target in patients with type 2 diabetes (DURATION-3): an open-label randomised trial.Lancet 2010;375:2234-43
-
(2010)
Lancet
, vol.375
, pp. 2234-43
-
-
Diamant, M.1
Van Gaal, L.2
Stranks, S.3
-
25
-
-
77953828230
-
DURATION-1 Study Group.DURATION-1: Exenatide once weekly produces sustained glycemic control and weight loss over 52 weeks
-
Buse JB, Drucker DJ, Taylor KL, et al.; DURATION-1 Study Group.DURATION-1: exenatide once weekly produces sustained glycemic control and weight loss over 52 weeks.Diabetes Care 2010;33:1255-61
-
(2010)
Diabetes Care
, vol.33
, pp. 1255-61
-
-
Buse, J.B.1
Drucker, D.J.2
-
26
-
-
77955573674
-
Efficacy and safety of exenatide once weekly versus sitagliptin or pioglitazone as an adjunct to metformin for treatment of type 2 diabetes (DURATION-2): A randomised trial
-
DURATION-2 Study Group
-
Bergenstal RM, Wysham C, Macconell L, et al.; DURATION-2 Study Group.Efficacy and safety of exenatide once weekly versus sitagliptin or pioglitazone as an adjunct to metformin for treatment of type 2 diabetes (DURATION-2): a randomised trial.Lancet 2010;376:431-9
-
(2010)
Lancet
, vol.376
, pp. 431-9
-
-
Bergenstal, R.M.1
Wysham, C.2
MacConell, L.3
-
27
-
-
79955960213
-
DURATION-2: Efficacy and safety of switching from maximum daily sitagliptin or pioglitazone to once-weekly exenatide
-
22 Mar 2011 [Epub ahead of print]
-
Wysham C, Bergenstal R, Malloy J, et al.DURATION-2: efficacy and safety of switching from maximum daily sitagliptin or pioglitazone to once-weekly exenatide.Diabet Med 22 Mar 2011 [Epub ahead of print]
-
Diabet Med
-
-
Wysham, C.1
Bergenstal, R.2
Malloy, J.3
-
28
-
-
79955818995
-
DURATION-4: Study results: BYDUREON efficacy and tolerability profile extended to monotherapy treatment
-
Amylin Pharmaceuticals [Last accessed 24 January 2011]
-
Amylin Pharmaceuticals.DURATION-4: study results: BYDUREON efficacy and tolerability profile extended to monotherapy treatment.Press release.Available from: http://investors.amylin.com/phoenix.zhtml?c=101911&p= irolnewsArticle&ID=1438147&highlight=) [Last accessed 24 January 2011]
-
Press Release
-
-
-
29
-
-
0037850667
-
Effect on glycemic control of exenatide (synthetic exendin-4) additive to existing metformin and/or sulfonylurea treatment in patients with type 2 diabetes
-
DOI 10.2337/diacare.26.8.2370
-
Fineman MS, Biscak TA, Shen LZ, et al.Effect on glycemic control of exenatide (synthetic exendin-4) additive to existing metformin and/or sulfonylurea treatment in patients with type 2 diabetes.Diabetes Care 2003;26:2370-7 (Pubitemid 36993328)
-
(2003)
Diabetes Care
, vol.26
, Issue.8
, pp. 2370-2377
-
-
Fineman, M.S.1
Bicsak, T.A.2
Shen, L.Z.3
Taylor, K.4
Gaines, E.5
Varns, A.6
Kim, D.7
Baron, A.D.8
-
30
-
-
79955794789
-
The incidence of antibody formation and the levels of antibodies are lower with liraglutide than exenatide in a head-to-head comparison [abstract 857-P]
-
20 - 24 September 2010, Stockholm, Sweden
-
Buse JB, Montanya E, Sesti G, et al.The incidence of antibody formation and the levels of antibodies are lower with liraglutide than exenatide in a head-to-head comparison [abstract 857-P].Presented at the 46th Annual Meeting of the European Association for the Study of Diabetes, 20 - 24 September 2010, Stockholm, Sweden.
-
46th Annual Meeting of the European Association for the Study of Diabetes
-
-
Buse, J.B.1
Montanya, E.2
Sesti, G.3
-
31
-
-
84920749196
-
-
18 June 2010 [Last accessed 6 March 2011]
-
Investor Update.18 June 2010.Available from: http://www.roche.com/ investors/ir-update [Last accessed 6 March 2011]
-
Investor Update
-
-
-
32
-
-
79955661908
-
DURATION-5: Exenatide once weekly resulted in greater improvements in glycemic control compared with exenatide twice daily in patients with type 2 diabetes
-
9 Feb 2011 [Epub ahead of print]
-
Blevins T, Pullman J, Malloy J, et al.DURATION-5: exenatide once weekly resulted in greater improvements in glycemic control compared with exenatide twice daily in patients with type 2 diabetes.J Clin Endocrinol Metab 9 Feb 2011 [Epub ahead of print]
-
J Clin Endocrinol Metab
-
-
Blevins, T.1
Pullman, J.2
Malloy, J.3
-
33
-
-
77955791233
-
Comparison of once-weekly with twice-daily exenatide in the treatment of type 2 diabetes (DURATION-1 trial)
-
Raskin P, Mohan A.Comparison of once-weekly with twice-daily exenatide in the treatment of type 2 diabetes (DURATION-1 trial).Expert Opin Pharmacother 2010;11:2269-71
-
(2010)
Expert Opin Pharmacother
, vol.11
, pp. 2269-71
-
-
Raskin, P.1
Mohan, A.2
-
34
-
-
67649304917
-
Use of a claims-based active drug safety surveillance system to assess the risk of acute pancreatitis with exenatide or sitagliptin compared to metformin or glyburide
-
Dore DD, Seeger JD, Arnold CK.Use of a claims-based active drug safety surveillance system to assess the risk of acute pancreatitis with exenatide or sitagliptin compared to metformin or glyburide.Curr Med Res Opin 2009;25:1019-27
-
(2009)
Curr Med Res Opin
, vol.25
, pp. 1019-27
-
-
Dore, D.D.1
Seeger, J.D.2
Arnold, C.K.3
-
35
-
-
79955832481
-
Incidence and relative incidence of medical record confirmed acute pancreatitis: Exenatide initiators compared to other antidiabetic drug initiators [abstract 543-P]
-
25 - 29 June 2010, Orlando, Florida, USA
-
Bloomgren G, Dore D, Wenton M, et al.Incidence and relative incidence of medical record confirmed acute pancreatitis: exenatide initiators compared to other antidiabetic drug initiators [abstract 543-P].Presented at the American Diabetes Association 70th Scientific Sessions, 25 - 29 June 2010, Orlando, Florida, USA.
-
American Diabetes Association 70th Scientific Sessions
-
-
Bloomgren, G.1
Dore, D.2
Wenton, M.3
-
36
-
-
79952696926
-
A retrospective cohort study to assess the relative risk of acute pancreatitis among initiators of exenatide compared to initiators of other antidiabetic medication: A follow up study [abstract 596-P]
-
25 - 29 June 2010, Orlando, Florida, USA
-
Wenten M, Gaebler J, Hussein M, et al.A retrospective cohort study to assess the relative risk of acute pancreatitis among initiators of exenatide compared to initiators of other antidiabetic medication: a follow up study [abstract 596-P].Presented at the American Diabetes Association 70th Scientific Sessions, 25 - 29 June 2010, Orlando, Florida, USA.
-
American Diabetes Association 70th Scientific Sessions
-
-
Wenten, M.1
Gaebler, J.2
Hussein, M.3
-
38
-
-
79955824993
-
The effects of exenatide on QTc interval in healthy subjects [abstract 597-P]
-
25 - 29 June 2010, Orlando, Florida, USA
-
Linnebjerg H, Seger M, Kothare P, et al.The effects of exenatide on QTc interval in healthy subjects [abstract 597-P].Presented at the American Diabetes Association 70th Scientific Sessions, 25 - 29 June 2010, Orlando, Florida, USA.
-
American Diabetes Association 70th Scientific Sessions
-
-
Linnebjerg, H.1
Seger, M.2
Kothare, P.3
|