Progress and prospects in cancer stem cell research for hepatocellular carcinoma

Chinese Journal of Cancer

Volumn 28, Issue 9, 2009, Pages

  Xu, Wen ^a   Cao, Lu ^a   Yin, Zheng Feng ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Cancer stem cells; Hepatocellular carcinoma; Stem cells

Indexed keywords

BETA CATENIN; BREAST CANCER RESISTANCE PROTEIN; CD133 ANTIGEN; EPITHELIAL CELL ADHESION MOLECULE; THY 1 ANTIGEN; TUMOR MARKER; WNT PROTEIN;

CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER RECURRENCE; CANCER RESEARCH; CANCER STEM CELL; CANCER SURGERY; HUMAN; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; METASTASIS; NONHUMAN; OUTCOME ASSESSMENT; POSTOPERATIVE COMPLICATION; PROTEIN EXPRESSION; RECURRENCE RISK; REVIEW; SIDE POPULATION CELL; SOLID TUMOR;

EID: 79955781825     PISSN: 1000467X     EISSN: 1944446X     Source Type: Journal    
DOI: 10.5732/cjc.008.10835     Document Type: Review

References (40)

1. Reya T, Morrison SJ, Clarke MF, et al. Stem cells, cancer, and cancer stem cells [J]. Nature, 2001, 414 (6859): 105-111.
2. Pardal R, Clarke MF, Morrison SJ. Applying the principles of stem-cell biology to cancer [J]. Nat Rev Cancer, 2003, 3 (12): 895-902.
3. Bergsagel DE, Valeriote FA. Growth characteristics of a mouse plasma cell tumor [J]. Cancer Res, 1968, 28 (11): 2187-2196.
4. Lapidot T, Sirard C, Vormoor J, et al. A cell initiating human acute myeloid leukaemia after transplantation into SCID mice [J]. Nature, 1994, 367(6464): 645-648.
5. Bonnet D, Dick JE. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell [J]. Nat Med, 1997, 3(7): 730-737.
6. Ni XG, Zhao P. Progress of cancer stem cells of solid tumor [J] Ai Zheng, 2006, 25(6): 775-778. [in Chinese]
7. Al-Hajj M, Wicha MS, Benito-Hernandez A, et al. Prospective identification of tumorigenic breast cancer cells [J]. Proc Natl Acad Sci USA, 2003, 100(7): 3983-3988.
8. Singh SK, Clarke ID, Terasaki M, et al. Identification of a cancer stem cell in human brain tumors [J]. Cancer Res, 2003, 63 (18): 5821-5828.
9. Singh SK, Hawkins C, Clarke ID, et al. Identification of human brain tumour initiating cells [J]. Nature, 2004, 432 (7015): 396-401.
10. Kim CF, Jackson EL, Woolfenden AE, et al. Identification of bronchioalveolar stem cells in normal lung and lung cancer [J]. Cell, 2005, 121 (6): 823-835.
11. Kuzmanov A, Hayrabedyan S, Karaivanov M, et al. Basal cell subpopulation as putative human prostate carcinoma stem cells [J]. Folia Histochem Cytobiol, 2007, 45(2): 75-80.
12. Li C, Heidt DG, Dalerba P, et al. Identification of pancreatic cancer stem cells [J]. Cancer Res, 2007, 67 (3): 1030-1037.
13. O'Brien CA, Pollett A, Gallinger S, et al. A human colon cancer cell capable of initiating tumour growth in immunodeficient mice [J]. Nature, 2007, 445 (7123): 106-110.
14. Friel AM, Sergent PA, Patnaude C, et al. Functional analyses of the cancer stem cell-like properties of human endometrial tumor initiating cells [J]. Cell Cycle, 2007, 7 (2): 242-249.
15. Alison MR. Liver cancer: a disease of stem cells? [J]. Panminerva Med, 2006, 48(3): 165-174.
16. Wu XZ, Yu XH. Bone marrow cells: the source of hepatocellular carcinoma? [J]. Medical Hypotheses, 2007, 69 (1): 36-42.
17. He YF, Liu YK, Lu HJ, et al. Comparative proteomic analysis of primary mouse liver c-Kit-(CD45/TER119)-stem/ progenitor cells [J]. J Cell Biochem, 2007, 102(4): 936-946.
18. Chiba T, Zheng YW, Kita K, et al. Enhanced self-renewal capability in hepatic stem/progenitor cells drives cancer initiation [J]. Gastroenterology, 2007, 133 (3): 937-950.
19. Gil-Benso R, Martinez-Lorente A, Pellin-Perez A, et al. Characterization of a new rat cell line established from 2'AAF-induced combined hepatocellular cholangiocellular carcinoma [J]. In Vitro Cell Dev Biol Anim, 2001, 37 (1): 17-25.
20. Chiba T, Kita K, Zheng YW, et al. Side population purified from hepatocellular carcinoma cells harbors cancer stem cell-like properties [J]. Hepatology, 2006, 44(1): 240-251.
21. Shi GM, Xu Y, Fan J, et al. Identification of side population cells in human hepatocellular carcinoma cell lines with stepwise metastatic potentials [J]. J Cancer Res Clin Oncol, 2008, 134(11): 1155-1163.
22. Shen G, Shen F, Shi Z, et al. Identification of cancer stemlike cells in the C6 glioma cell line and the limitation of current identification methods [J]. In Vitro Cell Dev Biol Anim, 2008, 44(7): 280-289.
23. + hepatocellular carcinoma cells as cancer stem/ progenitor cells [J]. Biochem Biophys Res Commun, 2006, 351(4): 820-824.
24. Yin S, Li J, Hu C, et al. CD133 positive hepatocellular carcinoma cells possess high capacity for tumorigenicity [J]. Int J Cancer, 2007, 120 (7): 1444-1450.
25. Ma S, Chan KW, Hu L, et al. Identification and characterization of tumorigenic liver cancer stem/progenitor cells [J]. Gastroenterology, 2007, 132(7): 2542-2556.
26. Song W, Li H, Tao K, et al. Expression and clinical significance of the stem cell marker CD133 in hepatocellular carcinoma [J]. Int J Clin Pract, 2008, 62(8): 1212-1218.
27. Salnikov AV, Kusumawidjaja G, Rausch V, et al. Cancer stem cell marker expression in hepatocellular carcinoma and liver metastases is not sufficient as single prognostic parameter. Cancer Lett, 2009, 275(2): 185-193.
28. Ho JW, Pang RW, Lau C, et al. Significance of circulatingendothelial progenitor cells in hepatocellular carcinoma [J]. Hepatology, 2006, 44(4): 836-843.
29. Ma S, Chan KW, Lee TK, et al. Aldehyde dehydrogenase discriminates the CD133 liver cancer stem cell populations [J]. Mol Cancer Res, 2008, 6(7): 1146-1153.
30. + cancer stem cells in human liver cancer [J]. Cancer Cell, 2008, 13 (2): 153-166.
31. Yang ZF, Ngai P, Ho DW, et al. Identification of local and circulating cancer stem cells in human liver cancer [J]. Hepatology, 2008, 47(3): 919-928.
32. + HCC cancer stem cells confer chemoresistance by preferential expression of the Akt/PKB survival pathway [J]. Oncogene, 2008, 27(12): 1749-1758.
33. Yamashita T, Budhu A, Forgues M, et al. Activation of hepatic stem cell marker EpCAM by Wnt-beta-catenin signaling in hepatocellular carcinoma [J]. Cancer Res, 2007, 67(22): 10831-10839.
34. Yamashita T, Forgues M, Wang W, et al. EpCAM and alphafetoprotein expression defines novel prognostic subtypes of hepatocellular carcinoma [J]. Cancer Res, 2008, 68 (5): 1451-1461.
35. Yamashita T, Ji J, Budhu A, et al. EpCAM-positive hepatocellular carcinoma cells are tumor-initiating cells with stem/progenitor cell features [J]. Gastroenterology, 2009, 136 (3): 1012-1024.
36. Yang W, Yan HX, Chen L, et al. Wnt/beta-catenin signaling contributes to activation of normal and tumorigenic liver progenitor cells [J]. Cancer Res, 2008, 68 (11): 4287-4295.
37. Tang Y, Kitisin K, Jogunoori W, et al. Progenitor/stem cells give rise to liver cancer due to aberrant TGF-beta and IL-6 signaling [J]. Proc Natl Acad Sci USA, 2008, 105 (7): 2445-2450.
38. Korkaya H, Wicha MS. Selective targeting of cancer stem cells: a new concept in cancer therapeutics [J]. BioDrugs, 2007, 21(5): 299-310.
39. Kamohara Y, Haraguchi N, Mimori K, et al. The search for cancer stem cells in hepatocellular carcinoma [J]. Surgery, 2008, 144(2): 119-124.
40. Mishra L, Banker T, Murray J, et al. Liver stem cells and hepatocellular carcinoma [J]. Hepatology, 2009, 49 (1): 318-329.