Serum omega-3 and omega-6 fatty acids and cutaneous p53 expression in an Australian population

Cancer Epidemiology Biomarkers and Prevention

Volumn 20, Issue 3, 2011, Pages 530-536

  Van Der Pols, Jolieke C ^a   Xu, Chunxia ^b   Boyle, Glen M ^b   Hughes, Maria C ^a   Carr, Samuel J ^a   Parsons, Peter G ^b   Green, Adèle C ^a  

^a ROYAL BRISBANE AND WOMEN'S HOSPITAL   (Australia)

^b QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

DOCOSAHEXAENOIC ACID; ICOSAPENTAENOIC ACID; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID; PROTEIN P53;

ADULT; AGED; ARTICLE; AUSTRALIA; BASEMENT MEMBRANE; CIGARETTE SMOKING; CROSS-SECTIONAL STUDY; EPIDERMIS; FEMALE; HUMAN; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MAJOR CLINICAL STUDY; MALE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PUNCH BIOPSY; QUESTIONNAIRE; SKIN CARCINOGENESIS; SUN EXPOSURE; ULTRAVIOLET RADIATION;

ADULT; AGED; AUSTRALIA; CELL TRANSFORMATION, NEOPLASTIC; CROSS-SECTIONAL STUDIES; DOCOSAHEXAENOIC ACIDS; EICOSAPENTAENOIC ACID; FATTY ACIDS, OMEGA-3; FATTY ACIDS, OMEGA-6; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; SKIN; SKIN NEOPLASMS; TUMOR SUPPRESSOR PROTEIN P53; ULTRAVIOLET RAYS;

EID: 79955776199     PISSN: 10559965     EISSN: None     Source Type: Journal    
DOI: 10.1158/1055-9965.EPI-10-0961     Document Type: Article

References (25)

1. International Agency for Research on Cancer. IARC Monographs on the evaluation of carcinogenic risks to humans, vol.55. Solar and ultraviolet radiation. Lyon, France: IARC;1992.
2. Eller MS, Asarch A, Gilchrest BA. Photoprotection in human skin - a multifaceted SOS response. Photochem Photobiol 2008;84:339-49. (Pubitemid 351421385)
3. Campbell C, Quinn AG, Ro YS, Angus B, Rees JL. p53 mutations are common and early events that precede tumor invasion in squamous cell neoplasia of the skin. J Invest Dermatol 1993;100:746-8. (Pubitemid 23151232)
4. Lacour JP. Carcinogenesis of basal cell carcinomas: genetics and molecular mechanisms. Br J Dermatol 2002;146 Suppl 61:17-9. (Pubitemid 34437805)
5. Pfeifer GP, Besaratinia A. Mutational spectra of human cancer. Hum Genet 2009;125:493-506.
6. Vousden KH, Ryan KM. p53 and metabolism. Nat Rev Cancer 2009;9:691-700.
7. Black HS, Rhodes LE. The potential of omega-3 fatty acids in the prevention of non-melanoma skin cancer. Cancer Detect Prev 2006;30:224-32. (Pubitemid 44163058)
8. Rhodes LE, Shahbakhti H, Azurdia RM, Moison RM, Steenwinkel MJ, Homburg MI, et al. Effect of eicosapentaenoic acid, an omega-3 polyunsaturated fatty acid, on UVR-related cancer risk in humans. An assessment of early genotoxic markers. Carcinogenesis 2003;24:919-25. (Pubitemid 36748909)
9. Rhodes LE, Gledhill K, Masoodi M, Haylett AK, Brownrigg M, Thody AJ, et al. The sunburn response in human skin is characterized by sequential eicosanoid profiles that may mediate its early and late phases. FASEB J 2009;23(11):3947-56.
10. Black HS, Thornby JI, Gerguis J, Lenger W. Influence of dietary omega-6, -3 fatty acid sources on the initiation and promotion stages of photocarcinogenesis. Photochem Photobiol 1992;56:195-9.
11. Sauer LA, Blask DE, Dauchy RT. Dietary factors and growth and metabolism in experimental tumors. J Nutr Biochem 2007;18:637-49. (Pubitemid 47385161)
12. Harris RB, Foote JA, Hakim IA, Bronson DL, Alberts DS. Fatty acid composition of red blood cell membranes and risk of squamous cell carcinoma of the skin. Cancer Epidemiol Biomarkers Prev 2005;14:906-12. (Pubitemid 40478555)
13. Van Der Pols JC, Xu C, Boyle GM, Parsons PG, Whiteman DC, Green AC. Expression of p53 tumor suppressor protein in sun-exposed skin and associations with sunscreen use and time spent outdoors: a community-based study. Am J Epidemiol 2006;163:982-8. (Pubitemid 43987589)
14. Green A, Battistutta D, Hart V, Leslie D, Marks G, Williams G, et al. The Nambour Skin Cancer and Actinic Eye Disease Prevention Trial: design and baseline characteristics of participants. Control Clin Trials 1994;15:512-22. (Pubitemid 24359727)
15. Green A, Williams G, Neale R, Hart V, Leslie D, Parsons P, et al. Daily sunscreen application and betacarotene supplementation in prevention of basal-cell and squamous-cell carcinomas of the skin: a randomised controlled trial. Lancet 1999;354:723-9. (Pubitemid 29405786)
16. Stratigos AJ, Kapranos N, Petrakou E, Anastasiadou A, Pagouni A, Christofidou E, et al. Immunophenotypic analysis of the p53 gene in non-melanoma skin cancer and correlation with apoptosis and cell proliferation. J Eur Acad Dermatol Venereol 2005;19:180-6. (Pubitemid 40450421)
17. Hussein MR. The TP53 tumor suppressor gene and melanoma tumorigenesis: is there a relationship?Tumour Biol 2004;25:200-7.
18. Dowell SP, Lane DP, Hall PA. The immunocytochemical detection of p53 protein in cytological specimens: technical considerations. Cytopathology 1994;5:76-81. (Pubitemid 24179056)
19. Whiteman DC, Parsons PG, Green AC. p53 expression and risk factors for cutaneous melanoma: a case-control study. Int J Cancer 1998;77:843-8. (Pubitemid 28378131)
20. Ling G, Persson A, Berne B, Uhlen M, Lundeberg J, Ponten F. Persistent p53 mutations in single cells from normal human skin. Am J Pathol 2001;159:1247-53. (Pubitemid 32947954)
21. Mantzioris E, Cleland LG, Gibson RA, Neumann MA, Demasi M, James MJ. Biochemical effects of a diet containing foods enriched with n-3 fatty acids. Am J Clin Nutr 2000;72:42-8. (Pubitemid 30441655)
22. Takemura N, Takahashi K, Tanaka H, Ihara Y, Ikemoto A, Fujii Y, et al. Dietary, but not topical, alpha-linolenic acid suppresses UVB-induced skin injury in hairless mice when compared with linoleic acids. Photochem Photobiol 2002;76:657-63.
23. Rhodes LE. Preventive oncology. Lancet 2004;363:1736-7.
24. Iversen L, Kragballe K. Arachidonic acid metabolism in skin health and disease. Prostaglandins Other Lipid Mediat 2000;63:25-42.
25. van Dam RM, Huang Z, Giovannucci E, Rimm EB, Hunter DJ, Colditz GA, et al. Diet and basal cell carcinoma of the skin in a prospective cohort of men. Am J Clin Nutr 2000;71:135-41. (Pubitemid 30033596)