P. falciparum modulates erythroblast cell gene expression in signaling and erythrocyte production pathways

PLoS ONE

Volumn 6, Issue 5, 2011, Pages

  Tamez, Pamela A ^a   Liu, Hui ^b   Wickrema, Amittha ^b   Haldar, Kasturi ^a  

^a UNIVERSITY OF NOTRE DAME   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHAPERONE;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL MATURATION; CHROMATOPHORE; CONTROLLED STUDY; CULTURE TECHNIQUE; ERYTHROBLAST; ERYTHROPOIESIS; GENE EXPRESSION REGULATION; HEAT SHOCK RESPONSE; HEMATOPOIETIC STEM CELL; HOST CELL; HOST PARASITE INTERACTION; HUMAN; HUMAN CELL; IMMUNOCOMPETENT CELL; IN VITRO STUDY; INFECTION SENSITIVITY; INTRACELLULAR SIGNALING; MALARIA FALCIPARUM; MOUSE; MULTINUCLEAR CELL; NONHUMAN; PLASMODIUM FALCIPARUM; TRANSCRIPTION REGULATION; ANIMAL; CELL CULTURE; CYTOLOGY; ERYTHROCYTE; GENETICS; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION;

PLASMODIUM FALCIPARUM;

ANIMALS; CELLS, CULTURED; ERYTHROBLASTS; ERYTHROCYTES; HEMATOPOIETIC STEM CELLS; HUMANS; PLASMODIUM FALCIPARUM; SIGNAL TRANSDUCTION;

EID: 79955775954     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0019307     Document Type: Article

References (30)

1. World Health Organization (2009) World Malaria Report 2009.
2. Mishra SK, Newton CR, (2009) Diagnosis and management of the neurological complications of falciparum malaria. Nat Rev Neurol 5: 189-198.
3. Haldar K, Mohandas N, (2009) Malaria, erythrocytic infection, and anemia. Hematology Am Soc Hematol Educ Program pp. 87-93.
4. Hiller NL, Bhattacharjee S, van Ooij C, Liolios K, Harrison T, et al. (2004) A host-targeting signal in virulence proteins reveals a secretome in malarial infection. Science 306: 1934-1937.
5. Marti M, Good RT, Rug M, Knuepfer E, Cowman AF, (2004) Targeting malaria virulence and remodeling proteins to the host erythrocyte. Science 306: 1930-1933.
6. Sargeant TJ, Marti M, Caler E, Carlton JM, Simpson K, et al. (2006) Lineage-specific expansion of proteins exported to erythrocytes in malaria parasites. Genome Biol 7: R12.
7. van Ooij C, Tamez P, Bhattacharjee S, Hiller NL, Harrison T, et al. (2008) The malaria secretome: from algorithms to essential function in blood stage infection. PLoS Pathog 4: e1000084.
8. Panichakul T, Sattabongkot J, Chotivanich K, Sirichaisinthop J, Cui L, et al. (2007) Production of erythropoietic cells in vitro for continuous culture of Plasmodium vivax. Int J Parasitol 37: 1551-1557.
9. Pasvol G, Jungery M, (1983) Glycophorins and red cell invasion by Plasmodium falciparum. Ciba Found Symp 94: 174-195.
10. Tamez PA, Liu H, Fernandez-Pol S, Haldar K, Wickrema A, (2009) Stage-specific susceptibility of human erythroblasts to Plasmodium falciparum malaria infection. Blood 114: 3652-3655.
11. Bei AK, Brugnara C, Duraisingh MT In vitro genetic analysis of an erythrocyte determinant of malaria infection. J Infect Dis 202: 1722-1727.
12. Li C, Wong WH, (2001) Model-based analysis of oligonucleotide arrays: expression index computation and outlier detection. Proc Natl Acad Sci U S A 98: 31-36.
13. Reich M, Liefeld T, Gould J, Lerner J, Tamayo P, et al. (2006) GenePattern 2.0. Nat Genet 38: 500-501.
14. Kim DW, Gazourian L, Quadri SA, Romieu-Mourez R, Sherr DH, et al. (2000) The RelA NF-kappaB subunit and the aryl hydrocarbon receptor (AhR) cooperate to transactivate the c-myc promoter in mammary cells. Oncogene 19: 5498-5506.
15. Harrison T, Samuel BU, Akompong T, Hamm H, Mohandas N, et al. (2003) Erythrocyte G protein-coupled receptor signaling in malarial infection. Science 301: 1734-1736.
16. Lodish H, Flygare J, Chou S, From stem cell to erythroblast: regulation of red cell production at multiple levels by multiple hormones. IUBMB Life 62: 492-496.
17. de Koning-Ward TF, Gilson PR, Boddey JA, Rug M, Smith BJ, et al. (2009) A newly discovered protein export machine in malaria parasites. Nature 459: 945-949.
18. Kulzer S, Rug M, Brinkmann K, Cannon P, Cowman A, et al. (2010) Parasite-encoded Hsp40 proteins define novel mobile structures in the cytosol of the P. falciparum-infected erythrocyte. Cell Microbiol 12: 1398-1420.
19. Elagib KE, Xiao M, Hussaini IM, Delehanty LL, Palmer LA, et al. (2004) Jun blockade of erythropoiesis: role for repression of GATA-1 by HERP2. Mol Cell Biol 24: 7779-7794.
20. Rusten LS, Dybedal I, Blomhoff HK, Blomhoff R, Smeland EB, et al. (1996) The RAR-RXR as well as the RXR-RXR pathway is involved in signaling growth inhibition of human CD34+ erythroid progenitor cells. Blood 87: 1728-1736.
21. Zhu J, Heyworth CM, Glasow A, Huang QH, Petrie K, et al. (2001) Lineage restriction of the RARalpha gene expression in myeloid differentiation. Blood 98: 2563-2567.
22. de Mast Q, Syafruddin D, Keijmel S, Riekerink TO, Deky O, et al. Increased serum hepcidin and alterations in blood iron parameters associated with asymptomatic P. falciparum and P. vivax malaria. Haematologica 95.
23. Prentice AM, Ghattas H, Doherty C, Cox SE, (2007) Iron metabolism and malaria. Food Nutr Bull 28: S524-539.
24. Tanno T, Bhanu NV, Oneal PA, Goh SH, Staker P, et al. (2007) High levels of GDF15 in thalassemia suppress expression of the iron regulatory protein hepcidin. Nat Med 13: 1096-1101.
25. Skorokhod OA, Caione L, Marrocco T, Migliardi G, Barrera V, et al. (2010) Inhibition of erythropoiesis in malaria anemia: role of hemozoin and hemozoin-generated 4-hydroxynonenal. Blood 116: 4328-4337.
26. Casals-Pascual C, Kai O, Cheung JO, Williams S, Lowe B, et al. (2006) Suppression of erythropoiesis in malarial anemia is associated with hemozoin in vitro and in vivo. Blood 108: 2569-2577.
27. Wickramasinghe SN, Phillips RE, Looareesuwan S, Warrell DA, Hughes M, (1987) The bone marrow in human cerebral malaria: parasite sequestration within sinusoids. Br J Haematol 66: 295-306.
28. Kang JA, Zhou Y, Weis TL, Liu H, Ulaszek J, et al. (2008) Osteopontin regulates actin cytoskeleton and contributes to cell proliferation in primary erythroblasts. J Biol Chem 283: 6997-7006.
29. Lovegrove FE, Pena-Castillo L, Mohammad N, Liles WC, Hughes TR, et al. (2006) Simultaneous host and parasite expression profiling identifies tissue-specific transcriptional programs associated with susceptibility or resistance to experimental cerebral malaria. BMC Genomics 7: 295.
30. Blader IJ, Manger ID, Boothroyd JC, (2001) Microarray analysis reveals previously unknown changes in Toxoplasma gondii-infected human cells. J Biol Chem 276: 24223-24231.