Erythrocyte G protein-coupled receptor signaling in malarial infection

Science

Volumn 301, Issue 5640, 2003, Pages 1734-1736

  Harrison, Travis ^a   Samuel, Benjamin U ^a,d   Akompong, Thomas ^a   Hamm, Heidi ^b   Mohandas, Narra ^c   Lomasney, Jon W ^a   Haldar, Kasturi ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NEW YORK BLOOD CENTER   (United States)

^d UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; DISEASES; MALARIA CONTROL; PROTEINS;

HUMAN MALARIA PARASITE;

BIOMEDICAL ENGINEERING;

ALPRENOLOL; CYCLIC AMP; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; ISOPRENALINE; PROPRANOLOL;

MALARIA; PROTEIN;

ARTICLE; DRUG EFFECT; DRUG MECHANISM; ERYTHROCYTE; HUMAN; IN VITRO STUDY; IN VIVO STUDY; LETHAL DOSE; MALARIA; NONHUMAN; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN SYNTHESIS; REGULATORY MECHANISM;

ADRENERGIC BETA-AGONISTS; ADRENERGIC BETA-ANTAGONISTS; ALPRENOLOL; ANIMALS; CATECHOLAMINES; CYCLIC AMP; ERYTHROCYTE MEMBRANE; ERYTHROCYTES; GTP-BINDING PROTEIN ALPHA SUBUNITS, GS; HUMANS; MALARIA; MEMBRANE MICRODOMAINS; MICE; PARASITEMIA; PEPTIDE FRAGMENTS; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM; PROPRANOLOL; RECEPTORS, ADRENERGIC, BETA-2; RECEPTORS, PURINERGIC P1; SIGNAL TRANSDUCTION; STEREOISOMERISM; VACUOLES;

PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM; PROTOZOA;

EID: 0141654989     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1089324     Document Type: Article

References (26)

1. L. H. Hiller, D. I. Baruch, K. Harsh, O. K. Doumbo, Nature 415. 673 (2002).
2. J. A. Dvorak, L. H. Miller, W. C. Whitehouse, T. Shiroshi, Science 187, 748 (1975).
3. H. E. Hamm, J. Biol. Chem. 273, 669 (1998).
4. S. R. Neves, P. T. Ram, R. Iyengar, Science 296, 1636 (2002).
5. K. L. Pierce, R. T. Premont, R. J. Lefkowitz, Nature Rev. Mol. Cell Biol. 3, 639 (2002).
6. S. L. Schrier, Clin. Haematol. 14, 1 (1985).
7. J. A. Chasis, M. Prenant, A. Leung, N. Mohandas, Blood 74, 1112 (1989).
8. S. A. Lauer et al., EMBO J. 19, 3556 (2000).
9. B. U. Samuel et al., J. Biol. Chem. 276, 29319 (2001).
10. A. Gilchrist et al., J. Biol. Chem. 273, 14912 (1998).
11. Single-letter abbreviations for the amino acid residues are as follows: E, Glu; H, His; L, Leu; M, Met; Q, Gln; R, Arg; and Y, Tyr.
12. A. Gilchrist, M. Bunemann, A. Li, M. M. Hosey, H. E. Hamm, J. Biol. Chem. 274, 6610 (1999).
13. M. J. Gardner et al., Nature 419, 498 (2002).
14. M. Dyer, K. Day, Mol. Biochem. Parasitol. 110, 437 (2000).
15. S. A. Desai, R. L. Rosenberg, Proc. Natl. Acad. Sci. U.S.A. 94, 2045 (1997).
16. T. Kenakin, Annu. Rev. Pharmacol. Toxicol. 42, 349 (2002).
17. R. A. Bond et al., Nature 374, 272 (1995).
18. C. Maack et al., Br. J. Pharmacol. 132, 1817 (2001).
19. W. Peters, B. L. Robinson, Ann. Trop. Med. Parasitol. 78, 561 (1984).
20. E. Nagao, K. B. Seydel, J. A. Dvorak, Exp. Parasitol. 102, 57 (2002).
21. J. M. Green et al., J. Cell. Biol. 146, 673 (1999).
22. J. E. Brittain, K. J. Mlinar, C. S. Anderson, E. P. Orringer, L. V. Parise, J. Clin. Investig. 107, 1555 (2001).
23. S. Etienne-Manneville, A. Hall, Nature 240, 629 (2002).
24. J. F. Vanhauwe et al., J. Biol. Chem. 277, 34143 (2002).
25. Materials and methods are available as supporting material on Science Online.
26. Supported by grants from the NIH to K.H. (AI39071 and HL69630), J.W.L. (HL55591 and HL03961), N.M. (DK32094), and H.H. (EY06062 and EY10291).