Hepoxilin A3 protects β-cells from apoptosis in contrast to its precursor, 12-hydroperoxyeicosatetraenoic acid

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1811, Issue 6, 2011, Pages 361-369

  Zafiriou, Maria Patapia ^a,d   Zelarayan, Laura Cecilia ^b   Noack, Claudia ^c   Renger, Anke ^c   Nigam, Santosh ^a   Siafaka Kapadai, Athanassia ^d  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b UNIVERSITY OF GÖTTINGEN   (Germany)

^c MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^d UNIVERSITY OF ATHENS   (Greece)

Author keywords

12(S) HpETE; Apoptosis; HXA3; Oxidative stress; Pancreatic beta cell

Indexed keywords

12 HYDROPEROXYICOSATETRAENOIC ACID; 15 HYDROPEROXYARACHIDONIC ACID; APOPTOSIS SIGNAL REGULATING KINASE 1; HEAT SHOCK PROTEIN 90; HEPOXILIN A; PHOSPHATASE; PHOSPHATASE 5; PROTEIN BCL 2; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; NONHUMAN; OXIDATIVE STRESS; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION;

12-HYDROXY-5,8,10,14-EICOSATETRAENOIC ACID; 8,11,14-EICOSATRIENOIC ACID; ANIMALS; APOPTOSIS; ARACHIDONATE 12-LIPOXYGENASE; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CELL LINE, TUMOR; CELL SURVIVAL; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, NEOPLASTIC; IMMUNOBLOTTING; INSULIN-SECRETING CELLS; MAP KINASE KINASE KINASE 5; NUCLEAR PROTEINS; PHOSPHOPROTEIN PHOSPHATASES; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 79955774318     PISSN: 13881981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbalip.2011.03.002     Document Type: Article

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